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List of works by B Mark Evers

A Retrospective Review: Patient-Reported Preoperative Prescription Opioid, Sedative, or Antidepressant Use is Associated with Worse Outcomes in Colorectal Surgery

scientific article published on 31 March 2020

A functional in vitro model to examine signaling mechanisms in gastrin-mediated human cell growth

scientific article published on January 1997

A new cecal slurry preparation protocol with improved long-term reproducibility for animal models of sepsis

scientific article

Absence of neurotensin attenuates intestinal dysbiosis and inflammation by maintaining Mmp7/α-defensin axis in diet-induced obese mice

scientific article published on 02 May 2020

Activation and role of MAP kinases in 15d-PGJ2-induced apoptosis in the human pancreatic cancer cell line MIA PaCa-2.

scientific article published on March 2004

Activation of AMPK Stimulates Neurotensin Secretion in Neuroendocrine Cells

scientific article

Activation of NF-kappaB binding in HT-29 colon cancer cells by inhibition of phosphatidylinositol 3-kinase

scientific article published on July 2000

Activation of PPARgamma increases PTEN expression in pancreatic cancer cells

scientific article published in January 2003

Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model

scientific article

Activation of conventional PKC isoforms increases expression of the pro-apoptotic protein Bad and TRAIL receptors

scientific article published on January 2002

Activation of phosphatidylinositol-3 kinase regulates pancreatic duodenal homeobox-1 in duct cells during pancreatic regeneration

scientific article published on March 2008

Acute pancreatitis results in induction of heat shock proteins 70 and 27 and heat shock factor-1

scientific article published on 01 October 2000

Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer.

scientific article published on 02 February 2017

Age-Associated Increase in Cytokine Production During Systemic Inflammation-II: The Role of IL-1β in Age-Dependent IL-6 Upregulation in Adipose Tissue

scientific article

Age-associated changes in gene expression patterns in the liver

scientific article published in May 2002

Age-associated increase in cytokine production during systemic inflammation: adipose tissue as a major source of IL-6

scientific article

Age-dependent increase of neurotensin expression in the ileum

scientific article published on 01 April 1994

Age-dependent reduction of the PI3K regulatory subunit p85α suppresses pancreatic acinar cell proliferation

scientific article

Age-dependent vulnerability to endotoxemia is associated with reduction of anticoagulant factors activated protein C and thrombomodulin

scientific article

Age-related changes in polyamine biosynthesis after fasting and refeeding

scientific article published in November 1993

Age‐dependent vulnerability to experimental acute pancreatitis is associated with increased systemic inflammation and thrombosis ⬇️

scientific article published on 04 July 2012

Aging is associated with decreased pancreatic acinar cell regeneration and phosphatidylinositol 3-kinase/Akt activation

scientific article published in May 2005

Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis.

scholarly article

Alterations of MAPK activities associated with intestinal cell differentiation

scientific article published on 01 June 2001

Alternative medicine products as a novel treatment strategy for inflammatory bowel disease

scientific article published on January 2008

Amiloride inhibits the growth of human colon cancer cells in vitro

scientific article published on 01 December 1992

Amplification of the HER-2/neu protooncogene in human endocrine tumors

scientific article published on 01 August 1992

An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors

scientific article published on 16 December 2019

An analysis of trends and growth factor receptor expression of GI carcinoid tumors

scientific article

An obligatory role for neurotensin in high-fat-diet-induced obesity

scientific article

Analysis of differential gene expression patterns in colon cancer and cancer stroma using microdissected tissues

scientific article

Analysis of multiple molecular changes in human endocrine tumours

scientific article published on June 1994

Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway

scientific article published on 19 April 2012

Assessment of differential gene expression patterns in human colon cancers

scientific article published on October 2000

Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line.

scientific article

BON cells display the intestinal pattern of neurotensin/neuromedin N precursor processing

scientific article published on August 1994

Biliary tract large cell neuroendocrine carcinoma: current evidence

scientific article published on 21 November 2019

Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: lessons learned of the EPR effect and image-guided drug delivery

scientific article published on 03 August 2013

Bombesin improves survival from methotrexate-induced enterocolitis

scientific article published on 01 October 1994

Bombesin induces angiogenesis and neuroblastoma growth

scientific article published on 26 March 2007

Bombesin inhibits growth of pancreatic ductal adenocarcinoma (H2T) in nude mice

scientific article published on September 1994

Bombesin stimulates growth of human gastrinoma

scientific article published on December 1, 1992

Bombesin stimulates mucosal growth in jejunal and ileal Thiry-Vella fistulas

scientific article published on 01 May 1995

Bombesin-mediated AP-1 activation in a human gastric cancer (SIIA).

scientific article

Breast Implant-Associated Anaplastic Large Cell Lymphoma: An Evidence-Based Systematic Review

scientific article published on 23 November 2020

Burn-induced transcriptional regulation of small intestinal ornithine decarboxylase ⬇️

scientific article published on January 1, 1992

Butyrate inhibits pancreatic cancer invasion ⬇️

scientific article published on November 1, 2003

Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis

scientific article published in August 2001

Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1 ⬇️

scientific article published on August 1, 1998

COX-2 inhibition results in alterations in nuclear factor (NF)-kappaB activation but not cytokine production in acute pancreatitis

scientific article published in May 2004

Caloric restriction increases the expression of heat shock protein in the gut.

scientific article published in May 1996

Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer.

scientific article

Capecitabine and Temozolomide in Neuroendocrine Tumor of Unknown Primary.

scientific article

Career track of Society of University Surgeons Resident Research Award recipients

scientific article

Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network

scientific article

Characterization of Promoter Elements Regulating the Expression of the Human Neurotensin/Neuromedin N Gene ⬇️

scientific article published on October 28, 2010

Characterization of functional neurotensin receptors on human lymphocytes.

scientific article published on August 1994

Characterization of promoter elements required for cell-specific expression of the neurotensin/neuromedin N gene in a human endocrine cell line

scientific article published on July 1995

Characterization of two novel proabsorptive peptide YY analogs, BIM-43073D and BIM-43004C

scientific article published on 01 March 1999

Chronic inflammation and pathogenesis of GI and pancreatic cancers.

scientific article

Colorectal cancer lung metastasis treatment with polymer-drug nanoparticles

scientific article published on 5 February 2018

Colorectal cancer: A new innate immune sensor - functions from inside the colonic epithelium

scientific article published on 15 February 2017

Comparative effects of neurotensin and neuromedin N on growth of human pancreatic cancer, MIA PaCa-2.

scientific article published on October 1993

Composition of PLGA and PEI/DNA nanoparticles improves ultrasound-mediated gene delivery in solid tumors in vivo.

scientific article published on 31 December 2007

Controllable self-assembly of RNA dendrimers

scientific article published on 2 December 2015

Cortivazol increases glucocorticoid receptor expression and inhibits growth of hamster pancreatic cancer (H2T) in vivo

scientific article published on 01 January 1993

Cotargeting the PI3K and RAS pathways for the treatment of neuroendocrine tumors

scientific article published on 17 January 2014

Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells

scientific article

Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.

scientific article

Current management of gastrointestinal carcinoid tumors

scientific article published in September 2004

Cyclic adenosine 5'-monophosphate-stimulated neurotensin secretion is mediated through Rap1 downstream of both Epac and protein kinase A signaling pathways.

scientific article published on 26 October 2006

Cyclooxygenase-2 gene disruption attenuates the severity of acute pancreatitis and pancreatitis-associated lung injury

scientific article published in October 2002

Cystosarcoma phyllodes (phyllodes tumor) of the male breast

scientific article published on 01 June 2003

Cytokine regulation of gut ornithine decarboxylase gene expression and enzyme activity

scientific article published on August 1, 1992

DNA methylation contributes to expression of the human neurotensin/neuromedin N gene ⬇️

scientific article published on March 1, 1998

De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer

scientific article published on 28 August 2018

Decreased pulmonary extracellular superoxide dismutase during systemic inflammation

scientific article

Delivery of RNA nanoparticles into colorectal cancer metastases following systemic administration

scientific article

Deptor is a novel target of Wnt/β-catenin/c-Myc and contributes to colorectal cancer cell growth.

scientific article published on 17 April 2018

Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors ⬇️

scientific article published on January 25, 2013

Development and characterization of a novel in vivo model of carcinoid syndrome

scientific article

Development of Halofluorochromic Polymer Nanoassemblies for the Potential Detection of Liver Metastatic Colorectal Cancer Tumors Using Experimental and Computational Approaches

scientific article published on 24 August 2017

Development of murine bariatric surgery models: lessons learned

scientific article published on 10 May 2018

Developmental expression of the neurotensin gene in the rat liver

scientific journal article

Diacylglycerol kinase regulation of protein kinase D during oxidative stress-induced intestinal cell injury

scientific article published on 09 August 2008

Differential effects of gut hormones on pancreatic and intestinal growth during administration of an elemental diet

scientific article published in May 1990

Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells

scientific article published on 27 July 2015

Differential expression of the neurotensin gene in the developing rat and human gastrointestinal tract

scientific article published in September 1993

Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer

scientific article

Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells

scientific article

Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop.

scientific article published on 17 November 2003

Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer

scientific article published on 15 February 2018

Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation

scientific article published on 15 February 2017

Effect of 5-fluorouracil, Optison and ultrasound on MCF-7 cell viability.

scientific article published in May 2006

Effect of aging on neurotensin-stimulated growth of rat small intestine

scientific article published on 01 August 1994

Effect of aging on the adaptive and proliferative capacity of the small bowel

scientific article

Effect of gut transposition on the expression of the endocrine gene neurotensin

scientific article published on 01 May 1998

Effect of ileocolonic transposition on gut morphology, gene expression, and function

scientific article published in January 2003

Effect of neurotensin on gut mucosal growth in rats with jejunal and ileal Thiry-Vella fistulas

scientific article published on 01 October 1992

Effect of total jejunoileal denervation on fat-stimulated release of peptide YY and cholecystokinin.

scientific article

Effectiveness of siRNA uptake in target tissues by various delivery methods

scientific article published on August 2007

Effects of 5-Azacytidine and Butyrate on Differentiation and Apoptosis of Hepatic Cancer Cell Lines ⬇️

scientific article published on June 1, 1998

Effects of aging on mortality, hypothermia, and cytokine induction in mice with endotoxemia or sepsis

scientific article published on 01 December 2003

Endocrine gene neurotensin: molecular mechanisms and a model of intestinal differentiation

scientific article

Endogenous cholecystokinin regulates growth of human cholangiocarcinoma

scientific article published on September 1989

Engineered nanopore of Phi29 DNA-packaging motor for real-time detection of single colon cancer specific antibody in serum

scientific article published on 30 October 2013

Enhancement of drug delivery in tumors by using interaction of nanoparticles with ultrasound radiation

scientific article

Enterotrophic effects of glucagon-like peptide 2 are enhanced by neurotensin.

scientific article

Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth ⬇️

scientific article published on August 1, 1991

Ets transcriptional regulation of gastrin-releasing peptide receptor in neuroblastomas

scientific article published on 01 August 2004

Ets1 transcription factor mediates gastrin-releasing peptide-induced IL-8 regulation in neuroblastoma cells

scientific article published on March 2007

Expression of neurotensin messenger RNA in a human carcinoid tumor

scientific article published on October 1991

Expression of neurotensin messenger RNA in a human pancreatic carcinoid tumor

scientific article published on 01 January 1992

FFAR4 Is Involved in Regulation of Neurotensin Release From Neuroendocrine Cells and Male C57BL/6 Mice.

scientific article published in August 2018

FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

scientific article (publication date: 6 December 2002)

Factors Contributing to Delay in Specialist Care After Colorectal Cancer Diagnosis in Kentucky

scientific article published on 20 October 2020

Fetal and neoplastic expression of the neurotensin gene in the human colon

scientific article published in May 1996

Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells.

scientific article published on 3 March 2017

Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression.

scientific article

FluorinatedN,N-Dialkylaminostilbenes Repress Colon Cancer by Targeting MethionineS-Adenosyltransferase 2A ⬇️

scientific article published on February 6, 2013

Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas

scientific article published on 19 May 2005

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

scientific article published on 12 March 2012

Gastrin-releasing peptide is a growth factor for human neuroblastomas.

scientific article

Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma

scholarly article

Gastrin-releasing peptide-induced down-regulation of tumor suppressor protein PTEN (phosphatase and tensin homolog deleted on chromosome ten) in neuroblastomas

scientific article published on 01 May 2005

Gastrinomas demonstrate amplification of the HER-2/neu proto-oncogene

scientific article published on June 1994

Gastrointestinal growth factors and neoplasia

scientific article

Geldanamycin decreases Raf-1 and Akt levels and induces apoptosis in neuroblastomas

scientific article published on January 2003

Gene expression profile of mouse white adipose tissue during inflammatory stress: age‐dependent upregulation of major procoagulant factors ⬇️

scientific article published on January 30, 2013

Global burden of neuroendocrine tumors and changing incidence in Kentucky.

scientific article

Glucagon-like peptide 2 is a potent growth factor for small intestine and colon

scientific article published on 01 March 1998

Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase

scientific article

Gut peptide receptor expression in human pancreatic cancers

scientific article

Gynecologic large cell neuroendocrine carcinoma: A review

scientific article published on 29 October 2020

Heat shock proteins are differentially expressed in human gastrointestinal cancers.

scientific article published in August 1995

High plasma levels of pro-NT are associated with increased colon cancer risk

scientific article published on 01 November 2020

Human colorectal cancers express a constitutively active cholecystokinin-B/gastrin receptor that stimulates cell growth

scientific article

Hydrodynamic delivery protocols

scientific article published on 01 January 2010

IGF-1 protects intestinal epithelial cells from oxidative stress-induced apoptosis

scientific article published on 26 September 2006

Immune checkpoint inhibitors in large cell neuroendocrine carcinoma: current status.

scientific article published on 22 February 2018

Immune checkpoint inhibitors in neuroendocrine tumors: A single institution experience with review of literature.

scientific article

Impact of the Affordable Care Act on Colorectal Cancer Screening, Incidence, and Survival in Kentucky

scientific article published on 22 February 2019

Improving the Quality of Cancer Care in Community Hospitals

scientific article published on 25 July 2020

In vivo investigation of hybrid Paclitaxel nanocrystals with dual fluorescent probes for cancer theranostics

scientific article published on 26 April 2013

Increased cell survival, migration, invasion, and Akt expression in PTHrP-overexpressing LoVo colon cancer cell lines

scientific article published on 10 January 2007

Increased coagulation and suppressed generation of activated protein C in aged mice during intra-abdominal sepsis

scientific article

Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

scientific article published on 20 April 2015

Increased incidence of well-differentiated thyroid cancer associated with Hashimoto thyroiditis and the role of the PI3k/Akt pathway.

scientific article published on 23 February 2007

Increases in nup475 and c-jun are early molecular events that precede the adaptive hyperplastic response after small bowel resection

scientific article published on 01 July 1995

Indirect inhibitory effect of a neurotensin receptor antagonist on human colon cancer (LoVo) growth

scientific article published on 01 October 1996

Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

scientific article published on 15 March 2019

Induction of apoptosis in human gastric cancer by sodium butyrate

scientific article published on 01 March 2000

Induction of cIAP-2 in Human Colon Cancer Cells through PKCδ/NF-κB ⬇️

scientific article published on 03 October 2003

Inflammation and the development of pancreatic cancer

scientific article

Inflammatory cytokine gene expression in mesenteric adipose tissue during acute experimental colitis

scientific article

Inflammatory mechanisms contributing to pancreatic cancer development

scientific article

Inhibition of aldose reductase prevents colon cancer metastasis

scientific article

Inhibition of alpha5 integrin decreases PI3K activation and cell adhesion of human colon cancers.

scientific article published on August 2004

Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer

scientific article published on 19 January 2012

Inhibition of gastric cancer by camptothecin involves apoptosis and multiple cellular pathways

scientific article published in August 1999

Inhibition of heat-shock protein 70 induction in intestinal cells overexpressing cyclooxygenase 2

scientific article published on 01 December 1998

Inhibition of mitochondrial gene transcription suppresses neurotensin secretion in the human carcinoid cell line BON.

scientific article published on 9 September 2004

Inhibition of neuroblastoma xenograft growth by Hsp90 inhibitors.

scientific article published on May 2006

Inhibition of neurotensin-induced pancreatic carcinoma growth by a nonpeptide neurotensin receptor antagonist, SR48692

scientific article published on 01 May 1997

Inhibition of pancreatic cancer cell growth and induction of apoptosis with novel therapies directed against protein kinase A.

scientific article published in August 2003

Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer

scientific article published on 24 September 2020

Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation

scientific article published in May 2001

Inhibition of transforming growth factor-beta/Smad signaling by phosphatidylinositol 3-kinase pathway

scientific article published on 18 January 2006

Integrating a 92-Gene Expression Analysis for the Management of Neuroendocrine Tumors of Unknown Primary

article

Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer.

scientific article published on 07 May 2012

Interferon-gamma induces caspase-8 in neuroblastomas without affecting methylation of caspase-8 promoter

scientific article published on April 2004

Interferon-mediated activation of the STAT signaling pathway in a human carcinoid tumor

scientific article published on 01 October 1998

Intestinal mitochondrial apoptotic signaling is activated during oxidative stress ⬇️

scientific article published on March 13, 2011

JMV1155: a novel inhibitor of glycine-extended progastrin-mediated growth of a human colon cancer in vivo

scientific article published on 01 January 1999

KLF4 deletion alters gastric cell lineage and induces MUC2 expression

scientific article published on 9 June 2016

Ketogenesis contributes to intestinal cell differentiation.

scientific article published on 09 December 2016

Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling

scientific article published on 27 March 2019

Longer operative time: deterioration of clinical outcomes of laparoscopic colectomy versus open colectomy

scientific article published on May 2014

Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

scientific article published on 28 February 2013

Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis

scientific article

MYCN silencing induces differentiation and apoptosis in human neuroblastoma cells.

scientific article published on 12 October 2006

Management of gallstone pancreatitis.

scientific article published on January 2006

Methods and assays for specific targeting and delivery of RNA nanoparticles to cancer metastases

scientific article published on 01 January 2015

Mitochondrial DNA damage and altered membrane potential (delta psi) in pancreatic acinar cells induced by reactive oxygen species

scientific article published on 01 August 1999

Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma

scientific article published on 04 August 2020

Molecular mechanisms contributing to glutamine-mediated intestinal cell survival

scientific article published on 4 October 2007

Molecular mechanisms contributing to necrotizing enterocolitis

scientific article published on 01 June 2001

Murine portal vein catheterization to analyze liver-directed therapies

scientific article published on 17 July 2013

Myristoylated alanine-rich C kinase substrate-mediated neurotensin release via protein kinase C-delta downstream of the Rho/ROK pathway.

scientific article

NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation.

scientific article published on 13 June 2013

NFATc1 Regulation of TRAIL Expression in Human Intestinal Cells ⬇️

scientific article published on May 16, 2011

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

scientific article published on 11 December 2017

Neurotensin Receptor 3/Sortilin Contributes to Tumorigenesis of Neuroendocrine Tumors Through Augmentation of Cell Adhesion and Migration

scientific article published on 19 December 2017

Neurotensin and growth of normal and neoplastic tissues

scientific article published on 9 August 2006

Neurotensin augments intestinal regeneration after small bowel resection in rats

scientific article published on 01 May 1992

Neurotensin expression and release in human colon cancers

scientific article published on 01 October 1992

Neurotensin phosphorylates GSK-3alpha/beta through the activation of PKC in human colon cancer cells

scientific article

Neurotensin prevents intestinal mucosal hypoplasia in rats fed an elemental diet ⬇️

scientific article published on 01 March 1992

Neurotensin stimulates growth of colon cancer

scientific article published on April 1, 1992

Neurotensin stimulates growth of colonic mucosa in young and aged rats ⬇️

scientific article published on 01 July 1992

Neurotensin, a novel target of Wnt/β-catenin pathway, promotes growth of neuroendocrine tumor cells

scientific article

Nonadherence to Standard of Care for Locally Advanced Colon Cancer as a Contributory Factor for High Mortality Rates in Kentucky

scientific article published on 13 February 2020

Novel Therapy for the Treatment of Human Carcinoid ⬇️

scientific article published on May 1, 1991

Novel and quantitative DNA dot-blotting method for assessment of in vivo proliferation.

scientific article published on 11 November 2004

Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation

scientific article published on 24 October 2019

Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression

scientific article

Novel expression and regulation of gastrin gene in human ovarian cancer cell line, SW626

scientific article published on July 1, 1998

Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer.

scientific article

Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer

scientific article published on August 2012

Nuclear factor of activated T cells (NFAT) signaling regulates PTEN expression and intestinal cell differentiation ⬇️

scientific article published on December 9, 2010

Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells ⬇️

scientific article published on June 13, 2012

Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway

scientific article

Optimal drug and gene delivery in cancer cells by ultrasound-induced cavitation.

scientific article

Organ physiology of aging.

scientific article published on February 1994

Overexpression of wild-type PKD2 leads to increased proliferation and invasion of BON endocrine cells

scientific article

Oxidative stress-induced intestinal epithelial cell apoptosis is mediated by p38 MAPK.

scientific article published on 29 September 2006

PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail

scientific article published on 10 February 2016

PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways

scientific article published on December 2010

PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.

scientific article

PI3K/Akt activation is critical for early hepatic regeneration after partial hepatectomy

scientific article published on 3 April 2008

PKCdelta-mediated regulation of FLIP expression in human colon cancer cells

scientific article published on January 2006

PKD prevents H2O2-induced apoptosis via NF-kappaB and p38 MAPK in RIE-1 cells

scientific article published on 04 December 2008

PKD1, PKD2, and their substrate Kidins220 regulate neurotensin secretion in the BON human endocrine cell line

scientific article published on 29 November 2007

PKD3 is the predominant protein kinase D isoform in mouse exocrine pancreas and promotes hormone-induced amylase secretion

scientific article

PKI-587 and Sorafenib Targeting PI3K/AKT/mTOR and Ras/Raf/MAPK Pathways Synergistically Inhibit HCC Cell Proliferation ⬇️

scientific article published on November 21, 2011

PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation

scientific article

PPAR-gamma agonist protects against intestinal injury during necrotizing enterocolitis

scientific article published on 27 December 2008

PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway

scientific article published in October 2002

PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells.

scientific article

PTHrP increases xenograft growth and promotes integrin alpha6beta4 expression and Akt activation in colon cancer.

scientific article published on 26 October 2007

PTP-PEST controls motility, adherens junction assembly, and Rho GTPase activity in colon cancer cells

scientific article

Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells

scientific article published on January 2002

Phorbol ester-induced alteration in the pattern of secretion and storage of chromogranin A and neurotensin in a human pancreatic carcinoid cell line

scientific article published on 01 May 1995

Phorbol ester-mediated neurotensin secretion is dependent on the PKC-alpha and -delta isoforms

scientific article published on November 2002

Phosphatidylinositol 3-kinase inhibition down-regulates survivin and facilitates TRAIL-mediated apoptosis in neuroblastomas

scientific article published on April 2004

Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells

scientific article published on October 2003

Phosphatidylinositol 3-kinase pathway regulates hypoxia-inducible factor-1 to protect from intestinal injury during necrotizing enterocolitis.

scientific article published on August 2007

Phosphatidylinositol 3-kinase regulation of gastrin-releasing peptide-induced cell cycle progression in neuroblastoma cells

scientific article published on 20 February 2007

Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis

scientific article

Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients

scientific article published on 11 August 2020

Postmastectomy Radiotherapy: Barriers to Implementation in a Disparate Population

scientific article published on 01 April 2020

Posttranscriptional regulation of neurotensin in the gut

scientific article published on August 1, 1991

Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.

scientific article

Preoperative opioid, sedative, and antidepressant use is associated with increased postoperative hospital costs in colorectal surgery

scientific article published on 09 October 2020

Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin ⬇️

scientific article published on September 1, 2003

Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells

scientific article published on 23 January 2004

Protein kinase Cdelta negatively regulates hedgehog signaling by inhibition of Gli1 activity

scientific article

Protein kinase D protects against oxidative stress-induced intestinal epithelial cell injury via Rho/ROK/PKC-delta pathway activation

scientific article published on 18 January 2006

Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation.

scientific article published in August 2005

RNA Nanoparticles Derived from Three-Way Junction of Phi29 Motor pRNA Are Resistant to I-125 and Cs-131 Radiation.

scientific article published on 27 May 2015

RNA interference: mechanisms of action and therapeutic consideration

scientific article published on November 2006

RORα suppresses breast tumor invasion by inducing SEMA3F expression

scientific article

Radiation-enhanced therapeutic targeting of galectin-1 enriched malignant stroma in triple negative breast cancer

scientific article published on 19 May 2016

Recent Advances in the Diagnosis and Treatment of Gastrointestinal Carcinoids ⬇️

scientific article published on January 1, 2011

Regulation of Ketogenic Enzyme HMGCS2 by Wnt/β-catenin/PPARγ Pathway in Intestinal Cells

scientific article published on 19 September 2019

Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition

scientific article published on August 2007

Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells

scientific article published on 24 July 2002

Regulation of growth of human gastric cancer by gastrin and glycine- extended progastrin ⬇️

scientific article published on 01 September 1997

Regulation of pancreatic duct cell differentiation by phosphatidylinositol-3 kinase. ⬇️

scientific article

Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway

scientific article published on March 2004

Regulation of proliferation, apoptosis and cell cycle in gastrointestinal disorders

scientific article published on 31 July 2009

Regulation of the potential marker for intestinal cells, Bmi1, by β-catenin and the zinc finger protein KLF4: implications for colon cancer

scientific article published on 14 December 2011

Requirement of c-Jun NH2-terminal kinase activation in interferon-alpha-induced apoptosis through upregulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in Daudi B lymphoma cells

scientific article published on October 2005

Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells ⬇️

scientific article published on January 20, 2012

Role of Gastrointestinal Hormones in the Proliferation of Normal and Neoplastic Tissues ⬇️

scientific article published on October 1, 2003

Role of bombesin on gut mucosal growth

scientific article published on 01 July 1995

Role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis

scientific article published on 11 December 2002

Role of gastrointestinal hormones in neuroblastoma

scientific article

Role of polyamine biosynthesis during gut mucosal adaptation after burn injury

scientific article published on 01 January 1993

Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells

scientific article (publication date: 2004)

S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2

scientific article published on 18 March 2019

SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and Differentiation

scientific article published on 16 January 2020

Selection criteria for combined resection of synchronous colorectal cancer hepatic metastases: a cautionary note

scientific article published on 11 January 2014

Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator

scientific article published in August 2003

Selective inhibition of NF-kappaB attenuates the severity of cerulein-induced acute pancreatitis

scientific article published in October 2002

Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death

scientific article published on August 2002

Sensitization of human colon cancer cells to TRAIL-mediated apoptosis

scientific article published in January 2001

Short-term caloric restriction augments age-related decreases in gastrin content and release

scientific article published in May 1996

Signal transduction pathways involved in oxidative stress-induced intestinal epithelial cell apoptosis

scientific article published on December 2005

Signaling mechanisms regulating bombesin-mediated AP-1 gene induction in the human gastric cancer SIIA

scientific article published on 01 August 2000

Small C-terminal domain phosphatase enhances snail activity through dephosphorylation

scientific article

Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1.

scientific article published on 20 December 2017

Somatostatin and Analogues in the Treatment of Cancer ⬇️

scientific article published on March 1, 1991

Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA ⬇️

scientific article published on June 13, 2012

Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression

scientific article published on 26 June 2020

Src-mediated activation of the human neurotensin/neuromedin N promoter ⬇️

scientific article published on August 1, 1997

Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion

scientific article

Stabilization of the transcription factors slug and twist by the deubiquitinase dub3 is a key requirement for tumor metastasis ⬇️

scientific article published on 24 August 2017

Stable RNA nanoparticles as potential new generation drugs for cancer therapy

scientific article

Stem cells in clinical practice

scientific article

Stem cells: what is their future in surgery?

scientific article

Stimulation of the intestinal Cdx2 homeobox gene by butyrate in colon cancer cells

scientific article published on April 2002

Suppression of Neurotensin Receptor Type 1 Expression and Function by Histone Deacetylase Inhibitors in Human Colorectal Cancers ⬇️

scientific article published on July 27, 2010

TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium.

scientific article published on 5 February 2015

Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL).

scientific article published on August 2005

Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer

scientific article

Targeted molecular therapy of the PI3K pathway: therapeutic significance of PI3K subunit targeting in colorectal carcinoma

scientific article published on June 2006

Targeting molecular pathways with camptothecin as novel therapy for gastric cancer

scientific article published on 01 November 1999

Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer

scientific article published in Nature Communications

Targeting the Wnt/β-catenin signaling pathway in liver cancer stem cells and hepatocellular carcinoma cell lines with FH535

scientific article

Temperature induces significant changes in both glycolytic reserve and mitochondrial spare respiratory capacity in colorectal cancer cell lines

scientific article

Temporal-specific and spatial-specific patterns of neurotensin gene expression in the small bowel

scientific article published on 01 November 1994

The PPARgamma ligand, 15d-PGJ2, attenuates the severity of cerulein-induced acute pancreatitis

scientific article

The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1

scientific article

The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies

scientific article published on 07 October 2020

The Society of University Surgeons in the 21st century--the mission, the vision, and the commitment to excellence

scientific article published in August 2002

The combined effect of epigenetic inhibitors for LSD1 and BRD4 alters prostate cancer growth and invasion

scientific article published on 05 January 2020

The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells

scientific article published on 26 September 2013

The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer ⬇️

scientific article published on March 5, 2012

The effect of PTEN on serotonin synthesis and secretion from the carcinoid cell line BON

scientific article

The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation

scientific article

The evolving role of the surgeon scientist

scientific article published on 14 January 2015

The human carcinoid cell line, BON. A model system for the study of carcinoid tumors

scientific article published on September 1994

The role of PI3K/mTOR inhibition in combination with sorafenib in hepatocellular carcinoma treatment

scientific article published on July 1, 2012

The role of ROS generation from magnetic nanoparticles in an alternating magnetic field on cytotoxicity.

scientific article

The role of Src family kinases in the normal and neoplastic gastrointestinal tract.

scientific article published on October 1996

The role of neurotensin in physiologic and pathologic processes

scientific article published on February 2011

The role of protein kinase D in neurotensin secretion mediated by protein kinase C-alpha/-delta and Rho/Rho kinase.

scientific article published on 27 April 2004

Toll-like receptor 4 activation increases Akt phosphorylation in colon cancer cells

scientific article

Translational research in gastric malignancy

scientific article published on April 2008

Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors

scientific article

Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1

scientific journal article

Tumor necrosis factor-alpha and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis

scientific article

Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration

scientific article published on 09 April 2013

Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy

scientific article published on 20 February 2020

Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers

scientific article published in August 2012

Unexpected growth-stimulatory effect of somatostatin analogue on cultured human pancreatic carcinoid cells

scientific article published in June 1992

Upregulation and redistribution of integrin alpha6beta4 expression occurs at an early stage in pancreatic adenocarcinoma progression

scientific article

Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer

scientific article published on 10 September 2020

VEGFR-2 expression in carcinoid cancer cells and its role in tumor growth and metastasis

scientific article

mTOR inhibitors in cancer therapy.

scientific article

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

scientific article published on 23 March 2011

mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON ⬇️

scientific article published on April 20, 2011

p27 Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells

scientific article published on 8 February 2008

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