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List of works by Oleg Schmidt-Kittler

A frequent kinase domain mutation that changes the interaction between PI3K  and the membrane

scientific article

A precision therapy against cancers driven by KIT/PDGFRA mutations.

scientific article published in November 2017

Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis

scientific article

Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket

scientific article published on September 2008

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

scientific article published on June 2005

PI3Kα Inhibitors That Inhibit Metastasis ⬇️

scientific article published on September 1, 2010

Somatic mutations in PI3Kalpha: structural basis for enzyme activation and drug design

scientific article

Structural basis of nSH2 regulation and lipid binding in PI3Kα.

scientific article

Synthesis and Pharmacological Evaluation of 4-Iminothiazolidinones for Inhibition of PI3 Kinase

scientific article published on January 2012

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

scientific article

Thiazolidinedione-based PI3Kα inhibitors: an analysis of biochemical and virtual screening methods

scientific article

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