List of works - Menghang Xia

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

scientific article

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries

scientific article

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

scientific article

Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition

scientific article

Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening

scientific article published on 19 February 2008

Compound cytotoxicity profiling using quantitative high-throughput screening

scientific article

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

scientific article

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

scientific article

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

scientific article published on 31 March 2016

High-throughput screening assays for the identification of chemical probes

scientific article published on August 2007

Identification and Profiling of Environmental Chemicals That Inhibit the TGFβ/SMAD Signaling Pathway

scientific article published on 11 November 2019

Identification of Compounds for Butyrylcholinesterase Inhibition

scientific article published on 16 July 2021

Identification of a potent new chemotype for the selective inhibition of PDE4

scientific article

Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory

scholarly article

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

scientific article

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

scientific article

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

scientific article

Phosphodiesterase 4 inhibitors enhance sexual pleasure-seeking activity in rodents

scientific article

Predictive Models for Human Organ Toxicity Based on In Vitro Bioactivity Data and Chemical Structure

scientific article published on 03 March 2020

Pyrazole-4-Carboxamide (YW2065): A Therapeutic Candidate for Colorectal Cancer via Dual Activities of Wnt/β-Catenin Signaling Inhibition and AMP-Activated Protein Kinase (AMPK) Activation

scientific article published on 10 December 2019

Systematic Identification of Molecular Targets and Pathways Related to Human Organ Level Toxicity

scientific article published on 29 November 2020

The pilot phase of the NIH Chemical Genomics Center

scientific article

Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features

scientific article published on 04 October 2009

List of works by Menghang Xia

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition

Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening

Compound cytotoxicity profiling using quantitative high-throughput screening

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

High-throughput screening assays for the identification of chemical probes

Identification and Profiling of Environmental Chemicals That Inhibit the TGFβ/SMAD Signaling Pathway

Identification of Compounds for Butyrylcholinesterase Inhibition

Identification of a potent new chemotype for the selective inhibition of PDE4

Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

Phosphodiesterase 4 inhibitors enhance sexual pleasure-seeking activity in rodents

Predictive Models for Human Organ Toxicity Based on In Vitro Bioactivity Data and Chemical Structure

Pyrazole-4-Carboxamide (YW2065): A Therapeutic Candidate for Colorectal Cancer via Dual Activities of Wnt/β-Catenin Signaling Inhibition and AMP-Activated Protein Kinase (AMPK) Activation

Systematic Identification of Molecular Targets and Pathways Related to Human Organ Level Toxicity

The pilot phase of the NIH Chemical Genomics Center

Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features