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List of works by Patrick R Griffin

A Combined Ligand‐ and Structure‐Based Virtual Screening Protocol Identifies Submicromolar PPARγ Partial Agonists

scientific article published on January 3, 2011

A Java API for working with PubChem datasets

scientific article published on January 6, 2011

A molecular switch regulating transcriptional repression and activation of PPARγ

scientific article published on 19 February 2020

A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects

scientific article published on May 25, 2011

Automated Hydrogen/Deuterium Exchange Electron Transfer Dissociation High Resolution Mass Spectrometry Measured at Single-Amide Resolution

scientific article published on December 1, 2011

Binding of the N-terminal Region of Coactivator TIF2 to the Intrinsically Disordered AF1 Domain of the Glucocorticoid Receptor Is Accompanied by Conformational Reorganizations

scientific article published on November 6, 2012

Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors

scientific article published on June 24, 2013

Correction: HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

scientific article published on 18 October 2019

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex

scientific article published on 7 January 2022

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex

scientific article published on April 10, 2011

Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ

scientific article published on 20 December 2019

Development of Novel Pharmacotherapeutics for Tobacco Dependence: Progress and Future Directions

scientific article published on September 27, 2012

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions

scientific article published on February 1, 2011

Direct interaction of a vancomycin derivative with bacterial enzymes involved in cell wall biosynthesis

scientific article published on November 1, 2001

Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1α/ERRγ complex

scientific article published on November 2, 2011

Genomic and Nongenomic Signaling Induced by 1α,25(OH)2-Vitamin D3 Promotes the Recovery of Amyloid-β Phagocytosis by Alzheimer's Disease Macrophages

scientific article published on January 1, 2012

HDX Workbench: Software for the Analysis of H/D Exchange MS Data

scientific article published on June 13, 2012

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity

scientific article published in Nature Communications

HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

scientific article published on 7 June 2019

Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling

scientific article published on 09 January 2019

Hydrogen/Deuterium Exchange Reveals Distinct Agonist/Partial Agonist Receptor Dynamics within Vitamin D Receptor/Retinoid X Receptor Heterodimer

scientific article published on October 13, 2010

Hydrophobic Interactions Improve Selectivity to ERα for Benzothiophene SERMs

scientific article published on March 8, 2012

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

scientific article published on July 6, 1995

Method To Compare Collision-Induced Dissociation Spectra of Peptides: Potential for Library Searching and Subtractive Analysis

scientific article published on September 1, 1998

Methods for the analysis of high precision differential hydrogen–deuterium exchange data

scientific article published on April 30, 2011

Molecular Cloning and Functional Expression of Mannitol-1-phosphatase from the Apicomplexan Parasite Eimeria tenella

scientific article published on February 13, 1998

Molecular glue CELMoD compounds are regulators of cereblon conformation

scientific article published on 4 November 2022

Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6

scientific article published on 16 October 2020

PubChem promiscuity: a web resource for gathering compound promiscuity data from PubChem

scientific article published on November 13, 2011

Quantitative structural assessment of graded receptor agonism

scientific article published on 14 October 2019

Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone

scientific article published on 07 February 2019

Structural and mechanistic bases for a potent HIV-1 capsid inhibitor

scientific article

Targeting Orphan Nuclear Receptors for Treatment of Metabolic Diseases and Autoimmunity

scientific article published on January 27, 2012

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.

scientific article published on 29 November 2018

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

scientific article published on July 25, 2013

Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways

scientific article published on 15 April 2019