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List of works by Tanguy Y Seiwert

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

scientific article published on 8 December 2016

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation ⬇️

scientific article published on October 26, 2012

A phase I study of pemetrexed, carboplatin, and concurrent radiotherapy in patients with locally advanced or metastatic non-small cell lung or esophageal cancer

scientific article published on 01 January 2007

A phase I trial of docetaxel based induction and concomitant chemotherapy in patients with locally advanced head and neck cancer

scientific article published in September 2007

A phase II study of lapatinib in recurrent/metastatic squamous cell carcinoma of the head and neck.

scientific article published on 27 February 2012

A pilot study of the pan-class I PI3K inhibitor buparlisib in combination with cetuximab in patients with recurrent or metastatic head and neck cancer

scientific article published on 04 September 2019

A randomized phase 2 network trial of tivantinib plus cetuximab versus cetuximab in patients with recurrent/metastatic head and neck squamous cell carcinoma

scientific article published on 19 February 2020

A randomized phase 2 study of temsirolimus and cetuximab versus temsirolimus alone in recurrent/metastatic, cetuximab-resistant head and neck cancer: The MAESTRO study

scientific article published on 04 May 2020

A randomized phase II study of 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy compared with bevacizumab plus 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy for intermediate-stage and T4N0-1 head and neck cancers ⬇️

scientific article published on February 17, 2011

A randomized, phase II study of afatinib versus cetuximab in metastatic or recurrent squamous cell carcinoma of the head and neck

scientific article

A value framework in head and neck cancer care

scientific article published in January 2014

AHNS Series - Do you know your guidelines? Principles of treatment for nasopharyngeal cancer: A review of the National Comprehensive Cancer Network guidelines

scientific article published on 29 November 2016

Abstract 1847: Influence of growth factors on resistance to EGFR inhibitor treatment in HNSCC - Temsirolimus as a potential concept

Abstract 2746: An evaluation of poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer

Abstract 2832: Fibroblast growth factors in head and neck cancer: Genetic alterations and therapeutic targeting with ponatinib

Abstract 4919: Pathway profiling of head and neck cancer cell lines

Abstract LB-398: Detection of copy number alterations in 124 head and neck squamous cell carcinomas using the Nanostring nCounter assay

Adjuvant chemoradiotherapy for locoregionally advanced and high-risk salivary gland malignancies ⬇️

scientific article published on July 26, 2011

An Immunogenomic Investigation of Oral Cavity Squamous Cell Carcinoma in Patients Aged 45 Years and Younger

scientific article published on 16 April 2020

Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort.

scientific article published on 19 September 2016

Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck

scientific article published on 25 April 2017

Chemoradiation for patients with large‐volume laryngeal cancers ⬇️

scientific article published on November 3, 2011

Chemoradiotherapy for locally advanced head and neck cancer

scientific article published on September 2007

Clinical Validation of a Next-Generation Sequencing Genomic Oncology Panel via Cross-Platform Benchmarking against Established Amplicon Sequencing Assays

scientific article published on 8 November 2016

Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040)

scientific article published on 03 April 2019

Comparison of outcomes of locoregionally advanced oropharyngeal and non-oropharyngeal squamous cell carcinoma over two decades

scientific article published on 30 October 2014

DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer

scientific article

Definitive chemoradiation for locally-advanced oral cavity cancer: A 20-year experience

scientific article published on 16 March 2018

Deintensification of treatment for human papillomavirus-related oropharyngeal cancer: Current state and future directions

scientific article published on 02 April 2020

Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer

scientific article published on 10 June 2019

Dose and Volume De-Escalation for Human Papillomavirus-Positive Oropharyngeal Cancer is Associated with Favorable Post-Treatment Functional Outcomes

scientific article published on 17 April 2020

EGFR-directed treatments in SCCHN ⬇️

scientific article published on June 6, 2013

Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin ⬇️

scientific article published on March 24, 2011

Effects of Vascular Endothelial Growth Factor Signaling Inhibition on Human Erythropoiesis ⬇️

scientific article published on July 30, 2013

Efficacy and safety of pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma: pooled analyses after long-term follow-up in KEYNOTE-012

scientific article published on 29 June 2018

Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study

scientific article

Ex vivo antibody-dependent cellular cytotoxicity inducibility predicts efficacy of cetuximab

scientific article

Expression and mutational analysis of MET in human solid cancers

scientific article published on December 2008

Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma

scientific article published on 26 May 2016

Final Results of a Randomized Phase 2 Trial Investigating the Addition of Cetuximab to Induction Chemotherapy and Accelerated or Hyperfractionated Chemoradiation for Locoregionally Advanced Head and Neck Cancer.

scientific article published on 7 May 2016

Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma

scientific article published on January 2006

Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation

scientific article published in January 2006

Genetic Landscape of Human Papillomavirus-Associated Head and Neck Cancer and Comparison to Tobacco-Related Tumors

scientific article

Genetic profiling of advanced radioactive iodine-resistant differentiated thyroid cancer and correlation with axitinib efficacy.

scientific article published on 29 January 2015

Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.

scientific article published on 23 February 2015

Growth factor expression mediates resistance to EGFR inhibitors in head and neck squamous cell carcinomas.

scientific article published on 26 March 2016

HPV-Associated Head and Neck Cancer

scientific article

HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas

scientific article

How Standard Is Second-Line Cetuximab in Recurrent or Metastatic Head and Neck Cancer in 2017?

article by Petr Szturz et al published 10 July 2017 in Journal of Clinical Oncology

IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade.

scientific article

Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma: implications for immunotherapy

scientific article published on 01 January 2019

Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma

scholarly article by Lili Ren et al published 2019 in OncoImmunology

Immune profiles in primary squamous cell carcinoma of the head and neck

scientific article published on 12 July 2019

Immunotherapy for Head and Neck Squamous Cell Carcinoma: A Review of Current and Emerging Therapeutic Options

scientific article

Impact of warm ischemia on phosphorylated biomarkers in head and neck squamous cell carcinoma

scientific article

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes

scientific article published on 9 December 2014

Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas

scientific article

MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma

scientific article

MET/PKCbeta expression correlate with metastasis and inhibition is synergistic in lung cancer

scientific article published on January 2009

Methylation of RAD51B, XRCC3 and other homologous recombination genes is associated with expression of immune checkpoints and an inflammatory signature in squamous cell carcinoma of the head and neck, lung and cervix

scientific article

Molecular Pathways in Head and Neck Cancer: EGFR, PI3K, and More ⬇️

scientific article published on January 1, 2013

Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition ⬇️

scientific article published on November 14, 2012

Molecular profiling of cancer--the future of personalized cancer medicine: a primer on cancer biology and the tools necessary to bring molecular testing to the clinic

scientific article published on April 2011

Molecular targeted therapies in head and neck cancer--an update of recent developments-

scientific article published on 14 April 2010

OPTIMA: a phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer

scientific article published on 01 October 2019

OPTIMA: a phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer

scientific article published on 01 February 2019

OPTIMA—A Phase 2 Trial of Induction Chemotherapy Response-Stratified Radiation Therapy Dose and Volume De-escalation for HPV+ Oropharyngeal Cancer: Efficacy, Toxicity, and HPV Subtype Analysis

article

Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA ⬇️

scientific article published on March 13, 2013

PD-L2 Expression in Human Tumors: Relevance to Anti-PD-1 Therapy in Cancer

scientific article

Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy

scientific article published in Science

Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion

scientific article

Pembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study.

scientific article published on 22 March 2017

Phase I Study of Apitolisib (GDC-0980), Dual Phosphatidylinositol-3-Kinase and Mammalian Target of Rapamycin Kinase Inhibitor, in Patients with Advanced Solid Tumors

scientific article

Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer

scientific article published in April 2008

Phase II study of gefitinib adaptive dose escalation to skin toxicity in recurrent or metastatic squamous cell carcinoma of the head and neck ⬇️

scientific article published on April 17, 2012

Phase II trial of pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated patients with squamous cell carcinoma of the head and neck ⬇️

scientific article published on 08 March 2011

Phase II trial of single-agent foretinib (GSK1363089) in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

scientific article published on 24 August 2012

Phase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer

scientific article

Phase Ib study of duligotuzumab (MEHD7945A) plus cisplatin/5-fluorouracil or carboplatin/paclitaxel for first-line treatment of recurrent/metastatic squamous cell carcinoma of the head and neck

scientific article

Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer

scientific article

Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation ⬇️

scientific article published on June 13, 2011

Prognostic value of pre-treatment CT texture analysis in combination with change in size of the primary tumor in response to induction chemotherapy for HPV-positive oropharyngeal squamous cell carcinoma

Protein kinase C beta in malignant pleural mesothelioma

scientific article published on October 2008

RON(MST1R)is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma ⬇️

scientific article published on July 1, 2011

Rare occurrence of EGFRvIII deletion in head and neck squamous cell carcinoma

scientific article published on 23 September 2014

Relationship between immune gene signatures and clinical response to PD-1 blockade with pembrolizumab (MK-3475) in patients with advanced solid tumors

scientific article published on 4 November 2015

Reply to s. Chakraborty et al

scientific article published on 09 February 2015

Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer

scientific article

Role of c-MET in upper aerodigestive malignancies--from biology to novel therapies

scientific article

Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population

scientific article

Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial

scientific article published on 27 May 2016

Similarity and difference in tumor-infiltrating lymphocytes in original tumor tissues and those of in vitro expanded populations in head and neck cancer

scientific article published on 19 December 2017

Single sample expression-anchored mechanisms predict survival in head and neck cancer

scientific article

Somatic mitochondrial mutation discovery using ultra-deep sequencing of the mitochondrial genome reveals spatial tumor heterogeneity in head and neck squamous cell carcinoma

scientific article published on 10 December 2019

State-of-the-art management of locally advanced head and neck cancer

scientific article

Targeting angiogenesis in head and neck cancer

scientific article published on 01 June 2008

The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma

scientific article

The chemoradiation paradigm in head and neck cancer

scientific article published on March 2007

The concurrent chemoradiation paradigm--general principles

scientific article published on February 2007

Ties that bind: p16 as a prognostic biomarker and the need for high-accuracy human papillomavirus testing

scientific article published on 3 November 2014

Time to Debunk an Urban Myth? The "Abscopal Effect" With Radiation and Anti-PD-1

scientific article published on 28 September 2020

Variations in HPV function are associated with survival in squamous cell carcinoma

scientific article published on 10 January 2019

WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.

scientific article published on 3 October 2014

mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas

scientific article

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