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List of works by Emanuela Caci

2-(dialkylamino)-4H-1-benzopyran-4-one derivatives modify chloride conductance in CFTR expressing cells

scientific article published in September 2003

A minimal isoform of the TMEM16A protein associated with chloride channel activity.

scientific article published on 30 May 2011

A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree.

scientific article published on 10 October 2012

Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy

scientific article published on 07 August 2018

Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.

scientific article published on 8 September 2005

Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia.

scientific article

Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.

scientific article published on 3 February 2007

CD4(+)CD25(high)CD127(-) regulatory T-cells in COPD: smoke and drugs effect

scientific article

CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds

scientific article published on 21 March 2003

Click-tambjamines as efficient and tunable bioactive anion transporters

scientific article published on 01 March 2020

Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.

scientific article

Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway

scientific article published on August 2012

Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.

scientific article

Effect of inflammatory stimuli on airway ion transport.

scientific article

Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA.

scientific article published on 21 August 2008

Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis

scientific article published in September 2013

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

scientific article published on 10 March 2016

Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis.

scientific article

Functional analysis of acid-activated Cl⁻ channels: properties and mechanisms of regulation.

scientific article published on January 2015

Functional human CFTR produced by a stable minichromosome

scientific article published on 16 August 2002

Gelsolin Secretion in Interleukin-4–treated Bronchial Epithelia and in Asthmatic Airways

scientific article published on 11 August 2005

Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.

scientific article published on 17 July 2015

Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release

scientific article published on 27 October 2016

High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel.

scientific article published on 20 November 2017

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions

scientific article

IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro

scientific article published on 01 January 2002

Increased expression of ATP12A proton pump in cystic fibrosis airways

scientific article published on 18 October 2018

Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms.

scientific article published on 24 June 2015

Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells

scientific article published on 13 September 2020

Methods for the Development and Analysis of Human Primary Airway Epithelia

article

Murine Rankl-/- Mesenchymal Stromal Cells Display an Osteogenic Differentiation Defect Improved by a RANKL-Expressing Lentiviral Vector

scientific article published on 18 January 2017

Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.

scientific article published on 02 June 2009

Non-canonical translation start sites in the TMEM16A chloride channel

scientific article published on 28 August 2013

Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia

scientific article published on 10 May 2018

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways

scientific article published on 7 April 2016

Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.

scientific article

SWATH label-free proteomics for cystic fibrosis research

scholarly article by Clarissa Braccia et al published 19 October 2018 in Journal of Cystic Fibrosis

Small Molecule Anion Carriers Correct Abnormal Airway Surface Liquid Properties in Cystic Fibrosis Airway Epithelia

scientific article published on 21 February 2020

Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.

scientific article

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

scientific article

TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels.

scientific article published in June 2013

The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism

The TMEM16A chloride channel as an alternative therapeutic target in cystic fibrosis.

scientific article published on April 2014

Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels

scientific article

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

scientific article published on 04 April 2019

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia.

scientific article published on 8 February 2018

Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin

scientific article published on 29 June 2015

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