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List of works by Ludwig Aigner

1H-nuclear magnetic resonance spectroscopy of glioblastoma cancer stem cells

scientific article published on 6 March 2011

A new technique for minimal invasive complete spinal cord injury in minipigs.

scientific article published on 12 January 2018

A nuclear magnetic resonance biomarker for neural progenitor cells: is it all neurogenesis?

scientific article published on 01 February 2009

A possible effect of montelukast on neurological aging examined by the use of register data

scientific article published on 09 October 2020

A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons

scientific article published on 31 December 2010

Adult hippocampus derived soluble factors induce a neuronal-like phenotype in mesenchymal stem cells

scientific article published on 17 August 2006

Adult mesenchymal stem cell therapy for myelin repair in Multiple Sclerosis

scientific article published on January 1, 2012

Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways

scientific article published in August 2003

Adult retinal pigment epithelium cells express neural progenitor properties and the neuronal precursor protein doublecortin

scientific article

Age Influences Microglial Activation After Cuprizone-Induced Demyelination

scientific article published on 20 September 2018

Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis

scientific article

Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination

scientific article published on 30 April 2019

Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.

scientific article published on 28 June 2016

Antisense Oligonucleotide in LNA-Gapmer Design Targeting TGFBR2-A Key Single Gene Target for Safe and Effective Inhibition of TGFβ Signaling

scientific article published on 12 March 2020

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

scientific article

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

scientific article published on 01 February 2020

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

scientific article published on 27 July 2020

Autologous adult rodent neural progenitor cell transplantation represents a feasible strategy to promote structural repair in the chronically injured spinal cord

scientific article published in March 2006

Beyond Clotting: A Role of Platelets in CNS Repair?

scientific article published in January 2015

Biomarkers in Traumatic Spinal Cord Injury-Technical and Clinical Considerations: A Systematic Review

scientific article published on 23 January 2020

Bone morphogenetic proteins prevent bone marrow stromal cell-mediated oligodendroglial differentiation of transplanted adult neural progenitor cells in the injured spinal cord

scientific article published on 16 May 2013

Brain and Retinal Pericytes: Origin, Function and Role

scientific article

Brain pericyte plasticity as a potential drug target in CNS repair

scientific article published on 22 December 2012

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

scientific article

Caffeine Compromises Proliferation of Human Hippocampal Progenitor Cells

scientific article published on 08 September 2020

Cellular Plasticity in the Adult Murine Piriform Cortex: Continuous Maturation of Dormant Precursors Into Excitatory Neurons.

scientific article published on 21 April 2018

Cerebrolysin protects PC12 cells from CoCl2-induced hypoxia employing GSK3β signaling

scientific article published on 2 August 2014

Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective

scientific article published on 24 September 2013

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease

scientific article published on 08 January 2020

Corrigendum: Human Cerebrospinal Fluid Promotes Neuronal Viability and Activity of Hippocampal Neuronal Circuits In Vitro

scientific article published on 10 October 2016

Cysteinyl leukotriene receptor 1 modulates autophagic activity in retinal pigment epithelial cells

scientific article published on 19 October 2020

Cystometric and External Urethral Sphincter Measurements in Awake Rats with Implanted Catheter and Electrodes Allowing for Repeated Measurements.

scientific article published on 30 January 2018

DCX+ neuronal progenitors contribute to new oligodendrocytes during remyelination in the hippocampus

scientific article published on 18 November 2020

DCX-Related Disorders

scientific article published on 7 February 2019

Deciphering the oligodendrogenic program of neural progenitors: cell intrinsic and extrinsic regulators.

scientific article published on May 2010

Diet-Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort

scientific article published on 09 July 2019

Dimethylsulfoxide Inhibits Oligodendrocyte Fate Choice of Adult Neural Stem and Progenitor Cells

scientific article published on 26 November 2019

Direct Potential Modulation of Neurogenic Differentiation Markers by Granulocyte-Colony Stimulating Factor (G-CSF) in the Rodent Brain

scientific article published in 2022

Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor

scientific article published on 01 July 2004

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

scientific journal article

Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration.

scientific article published in February 2008

Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?

scientific article published on 6 April 2018

Doublecortin expression levels in adult brain reflect neurogenesis

scientific article

Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease

scientific article published on 20 August 2016

Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition

article published in the Proceedings of the National Academy of Sciences of the United States of America

Early sacral neuromodulation ameliorates urinary bladder function and structure in complete spinal cord injury minipigs

scientific article published on 23 December 2019

Editorial: The Vascular Niche in Tissue Repair: A Therapeutic Target for Regeneration

scientific article published on 29 September 2017

Extracellular Vesicles Can Deliver Anti-inflammatory and Anti-scarring Activities of Mesenchymal Stromal Cells After Spinal Cord Injury

scientific article published on 29 November 2019

Functional Integration of Neuronal Precursors in the Adult Murine Piriform Cortex

scientific article published on 01 March 2020

Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis

scientific article published in March 2012

Genetic reprogramming of somatic cells into neuroblasts through a co-induction of the doublecortin gene along the Yamanaka factors: A promising approach to model neuroregenerative disorders

scientific article published on 12 April 2019

Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage

scientific article published on 28 July 2015

High Efficacy of Clonal Growth and Expansion of Adult Neural Stem Cells

scientific article published on 01 July 2003

Hippocampal neurogenesis and antidepressive therapy: shocking relations

scientific article

Human Adult Neurogenesis: Evidence and Remaining Questions

scientific article published on 18 April 2018

Human Cerebrospinal Fluid Promotes Neuronal Viability and Activity of Hippocampal Neuronal Circuits In Vitro

scientific article published on 4 March 2016

Human Wild-Type α-Synuclein Impairs Neurogenesis

article

Human in vitro reporter model of neuronal development and early differentiation processes

scientific article

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state

scientific article published on 27 October 2018

Identity, fate and potential of cells grown as neurospheres: species matters

scientific article published on 01 November 2011

Impaired TGF-β induced growth inhibition contributes to the increased proliferation rate of neural stem cells harboring mutant p53

scientific article

Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease.

scientific article

Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice

scientific article published on 23 December 2020

Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug

scientific article published on 25 February 2019

In Vivo Optical Imaging of Neurogenesis: Watching New Neurons in the Intact Brain

article

In situ labeling and imaging of endogenous neural stem cell proliferation and migration

scientific article

In vivo imaging of adult neurogenesis

scientific article published on March 1, 2011

In vivo monitoring of adult neurogenesis in health and disease.

scientific article

In vivo optical imaging of neurogenesis: watching new neurons in the intact brain

scientific article published in January 2008

Inhibition of leukotriene receptors boosts neural progenitor proliferation

scientific article published on 15 December 2011

Intrinsically active and pacemaker neurons in pluripotent stem cell-derived neuronal populations.

scientific article published on 20 February 2014

Lactation-induced reduction in hippocampal neurogenesis is reversed by repeated stress exposure

scientific article published on 19 February 2014

Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells

scientific article

Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons

scientific article published on 17 April 2008

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

scientific article published on 20 January 2020

Mesenchymal stem cell conditioning promotes rat oligodendroglial cell maturation

scientific article

Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells

scientific article published on 8 June 2006

Mesenchymal stem cells prime proliferating adult neural progenitors toward an oligodendrocyte fate

scientific article

Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures

scientific article published on 3 August 2009

Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer's Disease mice

scientific article published on 08 August 2020

Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice

scientific article published on 21 September 2018

Mitotic impairment by doublecortin is diminished by doublecortin mutations found in patients

scientific article published on 25 March 2004

Motor deficits following dorsal corticospinal tract transection in rats: voluntary versus skilled locomotion readouts.

scientific article

Mutational and expression analysis of the reelin pathway components CDK5 and doublecortin in gangliogliomas

scientific article published on 19 June 2002

Neural crest origin of retinal and choroidal pericytes

scientific article

Neural stem cells for spinal cord repair.

scientific article published on 03 March 2012

Neurodifferentiating potential of 8-prenylnaringenin and related compounds in neural precursor cells and correlation with estrogen-like activity

scientific article

Neurogenesis and neuronal regeneration in status epilepticus

scientific article

Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis

scientific article

Neurogenesis, Cellular Plasticity and Cognition: The Impact of Stem Cells in the Adult and Aging Brain – A Mini-Review

scientific article published on February 11, 2011

Neuroinflammatory alterations in trait anxiety: modulatory effects of minocycline

scientific article published on 30 July 2020

Neuronal precursor-specific activity of a human doublecortin regulatory sequence

scientific article published in January 2005

Neuroplasticity, limbic neuroblastosis and neuro-regenerative disorders

scientific article published on 01 August 2018

Nontraumatic spinal cord injury at the neurological intensive care unit: spectrum, causes of admission and predictors of mortality

scientific article published on 11 December 2015

Novel POMGnT1 mutations define broader phenotypic spectrum of muscle-eye-brain disease

scientific article published on 29 September 2007

Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis

scientific article published on 26 May 2008

Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors

scientific article published on 11 September 2008

Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice

scientific article published on October 20, 1995

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells

scientific article published on 27 March 2019

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

scientific article published on August 2017

Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease

scientific article published on 21 April 2007

Platelets in Amyloidogenic Mice Are Activated and Invade the Brain

scientific article published on 03 March 2020

Prolactin induces MAPK signaling in neural progenitors without alleviating glucocorticoid-induced inhibition of in vitro neurogenesis

scientific article published on 4 November 2009

Prolactin prevents chronic stress-induced decrease of adult hippocampal neurogenesis and promotes neuronal fate

scientific article published in February 2009

Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells

scientific article published on March 31, 1998

Proseek single-plex protein assay kit system to detect sAxl and Gas6 in serological material of brain tumor patients.

scientific article

Rat choroidal pericytes as a target of the autonomic nervous system

scientific article

Reactive Neuroblastosis in Huntington's Disease: A Putative Therapeutic Target for Striatal Regeneration in the Adult Brain

scientific article published on 9 March 2018

Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington's disease is accompanied by striatal invasion of neuroblasts

scientific article

Retinal Pericytes: Characterization of Vascular Development-Dependent Induction Time Points in an Inducible NG2 Reporter Mouse Model

scientific article published on 18 July 2018

SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina

scientific article published on 3 March 2017

Safe and Effective Cynomolgus Monkey GLP—Tox Study with Repetitive Intrathecal Application of a TGFBR2 Targeting LNA-Gapmer Antisense Oligonucleotide as Treatment Candidate for Neurodegenerative Disorders

scientific article published in 2022

Sex-dependent regulation of hippocampal neurogenesis under basal and chronic stress conditions in rats.

scientific article published on 18 March 2013

Smad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent manner

scientific article

SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis

scientific article

Stem cell metabolic and spectroscopic profiling

scientific article published on 04 February 2013

Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease

scientific article published on July 2010

Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb

scientific article published on 24 October 2005

Striatal transplantation for multiple system atrophy--are grafts affected by alpha-synucleinopathy?

scientific article

Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug

scientific article

TGF-beta in neural stem cells and in tumors of the central nervous system

scientific article published on 21 August 2007

TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons

scientific article

TGF-β Signaling: A Therapeutic Target to Reinstate Regenerative Plasticity in Vascular Dementia?

scientific article published on 23 July 2020

Tamoxifen Activation of Cre-Recombinase Has No Persisting Effects on Adult Neurogenesis or Learning and Anxiety

scientific article published on February 2017

Targeted transgene expression in neuronal precursors: watching young neurons in the old brain.

scientific article published in September 2006

Targeting TGF-ß in the Central Nervous System: Assessment of Cynomolgus Monkey—Toxicity and Pharmacokinetics for an LNA-Antisense Oligonucleotide

scientific article published in 2022

The Austrian Spinal Cord Injury Study: a registry for patients living with a traumatic spinal cord injury

scientific article published on 23 October 2017

The L-type calcium channel Cav1.3 is required for proper hippocampal neurogenesis and cognitive functions

scientific article published on 3 October 2015

The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies

scientific article published on 18 February 2020

The Leukotriene Receptor Antagonist Montelukast as a Potential COVID-19 Therapeutic

scientific article published on 17 December 2020

The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons

scientific article published on 24 July 2019

The TGF-β System As a Potential Pathogenic Player in Disease Modulation of Amyotrophic Lateral Sclerosis

scientific article published on 15 December 2017

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

scientific article

The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival

scientific article (publication date: September 2011)

The leukotriene signaling pathway: a druggable target in Alzheimer's disease

scientific article published on 18 September 2018

The maternal brain: an organ with peripartal plasticity

scientific article

The neurogenic competence of progenitors from the postnatal rat retina in vitro

scientific article published in May 2004

The remyelination Philosopher's Stone: stem and progenitor cell therapies for multiple sclerosis.

scientific article published on 10 February 2012

Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease

scientific article published on 19 May 2011

Transforming growth factor-beta1 is a negative modulator of adult neurogenesis

scientific article

Transforming growth factor-β1 primes proliferating adult neural progenitor cells to electrophysiological functionality

scientific article published on 30 August 2013

Transient expression of doublecortin during adult neurogenesis

scientific article (publication date: December 2003)

p57kip2 regulates glial fate decision in adult neural stem cells

scientific article published on 8 August 2012