List of works - Matthias Wiens

A (1-->3)-beta-D-glucan recognition protein from the sponge Suberites domuncula. Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression

scientific article

A cryptochrome-based photosensory system in the siliceous sponge Suberites domuncula (Demospongiae).

scientific article published in February 2010

A synthetic biology approach for the fabrication of functional (fluorescent magnetic) bioorganic-inorganic hybrid materials in sponge primmorphs

scientific article published on 18 February 2020

Acquisition of structure-guiding and structure-forming properties during maturation from the pro-silicatein to the silicatein form

scientific article

Advances in Research on Siliceous Sponge Spicules:Novel Insight into the Understanding of Biomineralization Mechanisms and Bionic Applications

article published in 2011

Allograft rejection in the mixed cell reaction system of the demosponge Suberites domuncula is controlled by differential expression of apoptotic genes

scientific article

An evolutionary perspective on the role of mesencephalic astrocyte-derived neurotrophic factor (MANF): At the crossroads of poriferan innate immune and apoptotic pathways

scientific article published on 18 March 2017

Arginine kinase in the demosponge Suberites domuncula: regulation of its expression and catalytic activity by silicic acid

scientific article published in February 2005

Assessing the root of bilaterian animals with scalable phylogenomic methods

scientific article

Axial (apical-basal) expression of pro-apoptotic and pro-survival genes in the lake baikal demosponge Lubomirskia baicalensis

scientific article

Bauplan of urmetazoa: basis for genetic complexity of metazoa

scientific article published in January 2004

Bio-silica and bio-polyphosphate: applications in biomedicine (bone formation).

scientific article published on 25 February 2012

Bio-sintering processes in hexactinellid sponges: fusion of bio-silica in giant basal spicules from Monorhaphis chuni

scientific article

Bio-vaterite formation by glycoproteins from freshwater pearls

scientific article published on 25 January 2010

Bioengineering of the silica-polymerizing enzyme silicatein-alpha for a targeted application to hydroxyapatite

scientific article published on 10 March 2010

Biogenic inorganic polysilicates (biosilica): formation and biomedical applications

scientific article published on January 2013

Biogenic origin of polymetallic nodules from the Clarion-Clipperton Zone in the Eastern Pacific Ocean: electron microscopic and EDX evidence

scientific article

Biosilica-based strategies for treatment of osteoporosis and other bone diseases

scientific article published on 01 January 2011

Biosilica: Molecular Biology, Biochemistry and Function in Demosponges as well as its Applied Aspects for Tissue Engineering

scientific article published on January 2012

Caspase-mediated apoptosis in sponges: cloning and function of the phylogenetic oldest apoptotic proteases from Metazoa

scientific article

Cellular effects of bacterial N-3-Oxo-dodecanoyl-L-Homoserine lactone on the sponge Suberites domuncula (Olivi, 1792): insights into an intimate inter-kingdom dialogue

scientific article

Characterization and osteogenic activity of a silicatein/biosilica-coated chitosan-graft-polycaprolactone

scientific article

Chemical Mimicry: Hierarchical 1D TiO2@ZrO2Core−Shell Structures Reminiscent of Sponge Spicules by the Synergistic Effect of Silicatein-α and Silintaphin-1

scientific article published on 01 April 2011

Circumferential spicule growth by pericellular silica deposition in the hexactinellid sponge Monorhaphis chuni

scientific article published on June 2011

Common genetic denominators for Ca++-based skeleton in Metazoa: role of osteoclast-stimulating factor and of carbonic anhydrase in a calcareous sponge

scientific article (publication date: 2012)

Concept of biogenic ferromanganese crust formation: coccoliths as bio-seeds in crusts from Central Atlantic Ocean (Senghor Seamount/Cape Verde).

scientific article published in May 2011

Deep metazoan phylogeny: when different genes tell different stories.

scientific article

Demosponge EST sequencing reveals a complex genetic toolkit of the simplest metazoans

scientific article (publication date: December 2010)

Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine) ⬇️

scientific article published on 18 January 2012

Differentiation capacity of epithelial cells in the sponge Suberites domuncula

scientific article published on 16 March 2004

Distribution of microfossils within polymetallic nodules: biogenic clusters within manganese layers

scientific article

Dual effect of inorganic polymeric phosphate/polyphosphate on osteoblasts and osteoclasts in vitro

scientific article

Dynamics of skeleton formation in the Lake Baikal sponge Lubomirskia baicalensis. Part II. Molecular biological studies

article

Evagination of cells controls bio-silica formation and maturation during spicule formation in sponges

scientific article

Evidence for a biogenic, microorganismal origin of rock varnish from the Gangdese Belt of Tibet

scientific article published on 13 December 2010

Evolution of metazoan cell junction proteins: the scaffold protein MAGI and the transmembrane receptor tetraspanin in the demosponge Suberites domuncula

scientific article published in July 2004

Flashing light signaling circuit in sponges: endogenous light generation after tissue ablation in Suberites domuncula.

scientific article

Formation of a micropatterned titania photocatalyst by microcontact printed silicatein on gold surfaces

scientific article published on 01 November 2012

Hardening of bio-silica in sponge spicules involves an aging process after its enzymatic polycondensation: evidence for an aquaporin-mediated water absorption

scientific article published on 2 May 2011

Identification and isolation of a retrotransposon from the freshwater sponge Lubomirskia baicalensis: implication in rapid evolution of endemic sponges

scientific article published on January 2009

Inducible ASABF-type antimicrobial peptide from the sponge Suberites domuncula: microbicidal and hemolytic activity in vitro and toxic effect on molluscs in vivo

scientific article published on 19 October 2011

Innate immune defense of the sponge Suberites domuncula against bacteria involves a MyD88-dependent signaling pathway. Induction of a perforin-like molecule

scientific article

Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2+ level in osteoblasts (SaOS-2 cells) in vitro

scientific article published on 30 March 2011

Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1.

scientific article published on 16 September 2011

Isolation and characterization of a Mn(II)-oxidizing Bacillus strain from the demosponge Suberites domuncula

scientific article

Isolation and characterization of two T-box genes from sponges, the phylogenetically oldest metazoan taxon

scientific article published on 24 July 2003

Isolation of the silicatein-α interactor silintaphin-2 by a novel solid-phase pull-down assay

scientific article

Manganese/polymetallic nodules: micro-structural characterization of exolithobiontic- and endolithobiontic microbial biofilms by scanning electron microscopy

scientific article

Mitochondrial genome of Suberites domuncula: palindromes and inverted repeats are abundant in non-coding regions

scientific article published on 10 January 2008

Molecular biomineralization: toward an understanding of the biogenic origin of polymetallic nodules, seamount crusts, and hydrothermal vents

scientific article

Molecular control of serial module formation along the apical-basal axis in the sponge Lubomirskia baicalensis: silicateins, mannose-binding lectin and mago nashi

scientific article published on 28 December 2005

Molecular mechanism of spicule formation in the demosponge Suberites domuncula: silicatein--collagen--myotrophin.

scientific article published on January 2003

Morphology of Sponge Spicules: Silicatein a Structural Protein for Bio-Silica Formation

NanoSIMS: Insights into the Organization of the Proteinaceous Scaffold within Hexactinellid Sponge Spicules

scientific article published on 01 May 2010

Nocturnin in the demosponge Suberites domuncula: a potential circadian clock protein controlling glycogenin synthesis in sponges

scientific article published on 01 December 2012

Novel photoreception system in sponges?

scientific article published on 02 June 2005

Okadaic acid, an apoptogenic toxin for symbiotic/parasitic annelids in the demosponge Suberites domuncula

scientific article

Osteogenic potential of a biosilica-coated P(UDMA-co-MPS) copolymer

scientific article published on 05 June 2013

Osteogenic potential of biosilica on human osteoblast-like (SaOS-2) cells

scientific article published on 20 August 2010

Pathogen-Mimicking MnO Nanoparticles for Selective Activation of the TLR9 Pathway and Imaging of Cancer Cells

Regional and modular expression of morphogenetic factors in the demosponge Lubomirskia baicalensis

scientific article published on 22 February 2007

Retinoid X receptor and retinoic acid response in the marine sponge Suberites domuncula

scientific article published in September 2003

Self-assembly and photocatalytic activity of branched silicatein/silintaphin filaments decorated with silicatein-synthesized TiO2 nanoparticles.

scientific article published on 5 May 2016

Silica transport in the demosponge Suberites domuncula: fluorescence emission analysis using the PDMPO probe and cloning of a potential transporter

scientific article (publication date: August 2004)

Silicase, an enzyme which degrades biogenous amorphous silica: contribution to the metabolism of silica deposition in the demosponge Suberites domuncula

scientific article published on January 2003

Silicatein expression in the hexactinellid Crateromorpha meyeri: the lead marker gene restricted to siliceous sponges

scientific article published on 31 May 2008

Silicatein-mediated incorporation of titanium into spicules from the demosponge Suberites domuncula.

scientific article published on 11 December 2009

Silicatein: nanobiotechnological and biomedical applications.

scientific article published in January 2009

Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber-like spicules

scientific article published on 17 April 2012

Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber-like spicules

scientific article published on 23 March 2018

Silicateins, the major biosilica forming enzymes present in demosponges: protein analysis and phylogenetic relationship

scientific article published on 28 February 2007

Silintaphin-1--interaction with silicatein during structure-guiding bio-silica formation

scientific article published on 04 March 2011

Sponge biosilica formation involves syneresis following polycondensation in vivo.

scientific article

Sponge spicules as blueprints for the biofabrication of inorganic-organic composites and biomaterials

scientific article (publication date: June 2009)

The 2'-5'-oligoadenylate synthetase in the lowest metazoa: isolation, cloning, expression and functional activity in the sponge Lubomirskia baicalensis

scientific article published on 12 September 2007

The molecular basis for the evolution of the metazoan bodyplan: extracellular matrix-mediated morphogenesis in marine demosponges

scientific article published in January 2003

The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells

scientific article published on 29 July 2010

The role of the silicatein-alpha interactor silintaphin-1 in biomimetic biomineralization

scientific article published on January 2009

The silicatein propeptide acts as inhibitor/modulator of self-organization during spicule axial filament formation

scientific article

The unique invention of the siliceous sponges: their enzymatically made bio-silica skeleton

scientific article published in January 2011

Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).

scientific article published on 26 December 2006

Towards a molecular systematics of the Lake Baikal/Lake Tuva sponges

scientific article

Traditional and Modern Biomedical Prospecting: Part II—The Benefits

scientific article

Two-Armed Activation of Bone Mineral Deposition by the Flavones Baicalin and Baicalein, Encapsulated in Polyphosphate Microparticles

scientific article published on 2 April 2017

Uptake of polyphosphate microparticles in vitro (SaOS-2 and HUVEC cells) followed by an increase of the intracellular ATP pool size

scientific article published on 29 December 2017

List of works by Matthias Wiens

A (1-->3)-beta-D-glucan recognition protein from the sponge Suberites domuncula. Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression

A cryptochrome-based photosensory system in the siliceous sponge Suberites domuncula (Demospongiae).

A synthetic biology approach for the fabrication of functional (fluorescent magnetic) bioorganic-inorganic hybrid materials in sponge primmorphs

Acquisition of structure-guiding and structure-forming properties during maturation from the pro-silicatein to the silicatein form

Advances in Research on Siliceous Sponge Spicules:Novel Insight into the Understanding of Biomineralization Mechanisms and Bionic Applications

Allograft rejection in the mixed cell reaction system of the demosponge Suberites domuncula is controlled by differential expression of apoptotic genes

An evolutionary perspective on the role of mesencephalic astrocyte-derived neurotrophic factor (MANF): At the crossroads of poriferan innate immune and apoptotic pathways

Arginine kinase in the demosponge Suberites domuncula: regulation of its expression and catalytic activity by silicic acid

Assessing the root of bilaterian animals with scalable phylogenomic methods

Axial (apical-basal) expression of pro-apoptotic and pro-survival genes in the lake baikal demosponge Lubomirskia baicalensis

Bauplan of urmetazoa: basis for genetic complexity of metazoa

Bio-silica and bio-polyphosphate: applications in biomedicine (bone formation).

Bio-sintering processes in hexactinellid sponges: fusion of bio-silica in giant basal spicules from Monorhaphis chuni

Bio-vaterite formation by glycoproteins from freshwater pearls

Bioengineering of the silica-polymerizing enzyme silicatein-alpha for a targeted application to hydroxyapatite

Biogenic inorganic polysilicates (biosilica): formation and biomedical applications

Biogenic origin of polymetallic nodules from the Clarion-Clipperton Zone in the Eastern Pacific Ocean: electron microscopic and EDX evidence

Biosilica-based strategies for treatment of osteoporosis and other bone diseases

Biosilica: Molecular Biology, Biochemistry and Function in Demosponges as well as its Applied Aspects for Tissue Engineering

Caspase-mediated apoptosis in sponges: cloning and function of the phylogenetic oldest apoptotic proteases from Metazoa

Cellular effects of bacterial N-3-Oxo-dodecanoyl-L-Homoserine lactone on the sponge Suberites domuncula (Olivi, 1792): insights into an intimate inter-kingdom dialogue

Characterization and osteogenic activity of a silicatein/biosilica-coated chitosan-graft-polycaprolactone

Chemical Mimicry: Hierarchical 1D TiO2@ZrO2Core−Shell Structures Reminiscent of Sponge Spicules by the Synergistic Effect of Silicatein-α and Silintaphin-1

Circumferential spicule growth by pericellular silica deposition in the hexactinellid sponge Monorhaphis chuni

Common genetic denominators for Ca++-based skeleton in Metazoa: role of osteoclast-stimulating factor and of carbonic anhydrase in a calcareous sponge

Concept of biogenic ferromanganese crust formation: coccoliths as bio-seeds in crusts from Central Atlantic Ocean (Senghor Seamount/Cape Verde).

Deep metazoan phylogeny: when different genes tell different stories.

Demosponge EST sequencing reveals a complex genetic toolkit of the simplest metazoans

Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine) ⬇️

Differentiation capacity of epithelial cells in the sponge Suberites domuncula

Distribution of microfossils within polymetallic nodules: biogenic clusters within manganese layers

Dual effect of inorganic polymeric phosphate/polyphosphate on osteoblasts and osteoclasts in vitro

Dynamics of skeleton formation in the Lake Baikal sponge Lubomirskia baicalensis. Part II. Molecular biological studies

Evagination of cells controls bio-silica formation and maturation during spicule formation in sponges

Evidence for a biogenic, microorganismal origin of rock varnish from the Gangdese Belt of Tibet

Evolution of metazoan cell junction proteins: the scaffold protein MAGI and the transmembrane receptor tetraspanin in the demosponge Suberites domuncula

Flashing light signaling circuit in sponges: endogenous light generation after tissue ablation in Suberites domuncula.

Formation of a micropatterned titania photocatalyst by microcontact printed silicatein on gold surfaces

Hardening of bio-silica in sponge spicules involves an aging process after its enzymatic polycondensation: evidence for an aquaporin-mediated water absorption

Identification and isolation of a retrotransposon from the freshwater sponge Lubomirskia baicalensis: implication in rapid evolution of endemic sponges

Inducible ASABF-type antimicrobial peptide from the sponge Suberites domuncula: microbicidal and hemolytic activity in vitro and toxic effect on molluscs in vivo

Innate immune defense of the sponge Suberites domuncula against bacteria involves a MyD88-dependent signaling pathway. Induction of a perforin-like molecule

Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2+ level in osteoblasts (SaOS-2 cells) in vitro

Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1.

Isolation and characterization of a Mn(II)-oxidizing Bacillus strain from the demosponge Suberites domuncula

Isolation and characterization of two T-box genes from sponges, the phylogenetically oldest metazoan taxon

Isolation of the silicatein-α interactor silintaphin-2 by a novel solid-phase pull-down assay

Manganese/polymetallic nodules: micro-structural characterization of exolithobiontic- and endolithobiontic microbial biofilms by scanning electron microscopy

Mitochondrial genome of Suberites domuncula: palindromes and inverted repeats are abundant in non-coding regions

Molecular biomineralization: toward an understanding of the biogenic origin of polymetallic nodules, seamount crusts, and hydrothermal vents

Molecular control of serial module formation along the apical-basal axis in the sponge Lubomirskia baicalensis: silicateins, mannose-binding lectin and mago nashi

Molecular mechanism of spicule formation in the demosponge Suberites domuncula: silicatein--collagen--myotrophin.

Morphology of Sponge Spicules: Silicatein a Structural Protein for Bio-Silica Formation

NanoSIMS: Insights into the Organization of the Proteinaceous Scaffold within Hexactinellid Sponge Spicules

Nocturnin in the demosponge Suberites domuncula: a potential circadian clock protein controlling glycogenin synthesis in sponges

Novel photoreception system in sponges?

Okadaic acid, an apoptogenic toxin for symbiotic/parasitic annelids in the demosponge Suberites domuncula

Osteogenic potential of a biosilica-coated P(UDMA-co-MPS) copolymer

Osteogenic potential of biosilica on human osteoblast-like (SaOS-2) cells

Pathogen-Mimicking MnO Nanoparticles for Selective Activation of the TLR9 Pathway and Imaging of Cancer Cells

Regional and modular expression of morphogenetic factors in the demosponge Lubomirskia baicalensis

Retinoid X receptor and retinoic acid response in the marine sponge Suberites domuncula

Self-assembly and photocatalytic activity of branched silicatein/silintaphin filaments decorated with silicatein-synthesized TiO2 nanoparticles.

Silica transport in the demosponge Suberites domuncula: fluorescence emission analysis using the PDMPO probe and cloning of a potential transporter

Silicase, an enzyme which degrades biogenous amorphous silica: contribution to the metabolism of silica deposition in the demosponge Suberites domuncula

Silicatein expression in the hexactinellid Crateromorpha meyeri: the lead marker gene restricted to siliceous sponges

Silicatein-mediated incorporation of titanium into spicules from the demosponge Suberites domuncula.

Silicatein: nanobiotechnological and biomedical applications.

Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber-like spicules

Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber-like spicules

Silicateins, the major biosilica forming enzymes present in demosponges: protein analysis and phylogenetic relationship

Silintaphin-1--interaction with silicatein during structure-guiding bio-silica formation

Sponge biosilica formation involves syneresis following polycondensation in vivo.

Sponge spicules as blueprints for the biofabrication of inorganic-organic composites and biomaterials

The 2'-5'-oligoadenylate synthetase in the lowest metazoa: isolation, cloning, expression and functional activity in the sponge Lubomirskia baicalensis

The molecular basis for the evolution of the metazoan bodyplan: extracellular matrix-mediated morphogenesis in marine demosponges

The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells

The role of the silicatein-alpha interactor silintaphin-1 in biomimetic biomineralization

The silicatein propeptide acts as inhibitor/modulator of self-organization during spicule axial filament formation