List of works - Jochen Springer

ACE Inhibitors and Sarcopenia: Covering All the BASEs?

scientific article published on 01 November 2016

Acylated ghrelin treatment normalizes skeletal muscle mitochondrial oxidative capacity and AKT phosphorylation in rat chronic heart failure

scientific article published on 3 November 2017

Adiponectin resistance in heart failure and the emerging pattern of metabolic failure in chronic heart failure

scientific article published on 01 March 2010

Advances in cachexia and sarcopenia research in the heart failure context: call for action

scientific article

Animal models of cachexia and sarcopenia in chronic illness: Cardiac function, body composition changes and therapeutic results

scientific article published on 2 April 2017

Atrial natriuretic peptide and related peptides

scientific article published on January 2007

Bile acids for cachexia therapy : Reply to the letter by Shailendra Kapoor: Ursodeoxycholic acid and its emerging role in attenuation of tumor growth in gastrointestinal malignancies

scientific article published on December 2012

Biomarkers for cancer cachexia: where do we stand?

scientific article published on 30 November 2020

Biomarkers for chronic heart failure.

scientific article published on January 2007

Blocking myostatin: muscle mass equals muscle strength?

scientific article published on 01 December 2020

Body weight changes and incidence of cachexia after stroke

scientific article published on 24 January 2019

Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?!

scientific article

Cachexia in chronic heart failure: prognostic implications and novel therapeutic approaches

scientific article

Cachexia in heart disease: highlights from the ESC 2010

scientific article

Cachexia research in Japan: facts and numbers on prevalence, incidence and clinical impact

scientific article published on 12 April 2016

Cardiac cachexia: a systematic overview

scientific article

Cardiac cachexia: hic et nunc

scientific article

Cardiac cachexia: hic et nunc: "hic et nunc" - here and now.

scientific article published on 23 October 2015

Cardiac expression of neutrophil gelatinase-associated lipocalin in a model of cancer cachexia-induced cardiomyopathy

scientific article published on 26 October 2018

Cardiac muscle wasting in individuals with cancer cachexia

scientific article

Cardiovascular function and predictors of exercise capacity in patients with colorectal cancer

scientific article published in September 2014

Catabolic signaling and muscle wasting after acute ischemic stroke in mice: indication for a stroke-specific sarcopenia

scientific article published on 28 October 2014

Clinical perspective for wasting in diaphragm, an ever-trained muscle

scientific article published on 13 June 2016

Clinical problems of patients with cachexia due to chronic illness: a congress report

scientific article published on 04 October 2020

Comparison of sarcopenia and cachexia in men with chronic heart failure: results from the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF)

scientific article published on 30 August 2018

Concern regarding quality and quality of muscle

scientific article published on 3 November 2015

Considering technique of assessment and method for normalizing skeletal muscle mass

scientific article

Detection of muscle wasting in patients with chronic heart failure using C-terminal agrin fragment: results from the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF).

scientific article published on 9 October 2015

Developing models for cachexia and their implications in drug discovery

scientific article published on 30 April 2015

Effect of application route of the ghrelin analog BIM-28131 (RM-131) on body weight and body composition in a rat heart failure model

scientific article published on 7 March 2013

Effect of ghrelin and its analogues, BIM‐28131 and BIM‐28125, on the expression of myostatin in a rat heart failure model ⬇️

scientific article published on September 18, 2012

Energy metabolism in human renin-gene transgenic rats: does renin contribute to obesity?

scientific article published on 26 January 2009

Erythropoietin improves cardiac wasting and outcomes in a rat model of liver cancer cachexia

scientific article published on 14 May 2016

Febuxostat improves outcome in a rat model of cancer cachexia

scientific article published on 21 April 2015

Formoterol in the treatment of experimental cancer cachexia: effects on heart function

scientific article published on 29 August 2014

Furosemide induces mortality in a rat model of chronic heart failure

scientific article

Ghrelin and its analogues, BIM-28131 and BIM-28125, improve body weight and regulate the expression of MuRF-1 and MAFbx in a rat heart failure model

scientific article

Growth differentiation factor-15 as a prognostic biomarker in cancer patients

scientific article published on 22 May 2016

Heart failure epidemiology and novel treatments in Japan: facts and numbers

scientific article published on 2 August 2016

Highlights of mechanistic and therapeutic cachexia and sarcopenia research 2010 to 2012 and their relevance for cardiology.

scientific article

Highlights of the mechanistic and therapeutic cachexia and sarcopenia research 2010 to 2012 and their relevance for cardiology

scientific article

Hypermetabolism: should cancer types, pathological stages and races be considered in assessing metabolism and could elevated resting energy expenditure be the therapeutic target in patients with advanced cancer?

scientific article

IGF-1 treatment reduces weight loss and improves outcome in a rat model of cancer cachexia

scientific article

Impact of Plasma Kynurenine Level on Functional Capacity and Outcome in Heart Failure　- Results From Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF).

scientific article

In vivomodels of cardiac diseases: application to drug development and screening ⬇️

scientific article published on January 1, 2010

Influence of cancer cachexia on drug liver metabolism and renal elimination in rats

scientific article

Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia

scientific article published on 9 July 2012

Insulin resistance in heart failure: differences between patients with reduced and preserved left ventricular ejection fraction

scientific article published on 21 July 2015

Irisin - a myokine potentially bridging muscle and fat tissue in cachexia

scientific article published on 21 October 2015

Is cardiac wasting accompanied by skeletal muscle loss in breast cancer patients receiving anticancer treatment?

scientific article published on 28 August 2017

Leukocyte redistribution: effects of beta blockers in patients with chronic heart failure

scientific article

Lipopolysaccharide responsiveness is an independent predictor of death in patients with chronic heart failure

scientific article published on 8 August 2015

Liquid chromatography-tandem mass spectrometry method for simultaneous quantification of bisoprolol, ramiprilat, propranolol and midazolam in rat dried blood spots

scientific article published on 15 March 2014

Liver metabolism in cardiac cachexia ⬇️

scientific article published on November 2, 2012

MT-102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia

scientific article published on 17 February 2020

Mechanism and novel therapeutic approaches to wasting in chronic disease

scientific article published on 09 May 2013

Megestrol acetate improves cardiac function in a model of cancer cachexia-induced cardiomyopathy by autophagic modulation

scientific article published on 7 April 2016

MicroRNAs in muscle wasting

Molecular mechanisms and treatment targets of muscle wasting and cachexia in heart failure: an overview

scientific article published on March 2014

Muscle Wasting and Sarcopenia in Heart Failure-The Current State of Science

scientific article published on 08 September 2020

Muscle wasting and cachexia in heart failure: mechanisms and therapies

scientific article

Muscle wasting and sarcopenia in heart failure and beyond: update 2017.

scientific article published in November 2017

Muscle wasting in cardiac cachexia

scientific article

Muscle wasting in heart failure: An overview

scientific article published on 07 May 2013

Muscle wasting: an overview of recent developments in basic research

scientific article

Muscle wasting: an overview of recent developments in basic research

scientific article published on 23 August 2014

Myostatin signaling is up-regulated in female patients with advanced heart failure

scientific article published on 4 April 2017

Myostatin: Regulator of muscle wasting in heart failure and treatment target for cardiac cachexia.

scientific article

Neuromuscular electrical stimulation for muscle wasting in heart failure patients

scientific article

No effects of human ghrelin on cardiac function despite profound effects on body composition in a rat model of heart failure

scientific article published on 23 August 2008

Novel mechanism of ghrelin therapy for cachexia

scientific article published on 27 October 2015

Novel treatment approaches to cachexia and sarcopenia: highlights from the 5th Cachexia Conference

scientific article published on 01 April 2010

Nutrition in cachexia: from bench to bedside

scientific article published on 11 March 2016

Overweight and obesity are associated with improved survival, functional outcome, and stroke recurrence after acute stroke or transient ischaemic attack: observations from the TEMPiS trial ⬇️

scientific article published on October 16, 2012

Pharmacokinetics of drugs in cachectic patients: a systematic review

scientific article (publication date: 2013)

Physical activity for the prevention and treatment of sarcopenic obesity

scientific article published on June 2017

Preserved Skeletal Muscle Mitochondrial Function, Redox State, Inflammation and Mass in Obese Mice with Chronic Heart Failure

scientific article published on 04 November 2020

Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

scientific article published on 29 August 2013

Procalcitonin-guided antibiotic treatment in heart failure

scientific article

Prognosis and therapy approaches of cardiac cachexia

scientific article

Promising models for cancer-induced cachexia drug discovery

scientific article published on 13 February 2020

Protein levels in Keap1-Nrf2 system in human failing heart

scientific article published in October 2016

Publication trends in cachexia and sarcopenia in elderly heart failure patients

scientific article published on 24 November 2016

Reply to letter to the editor "suramin against myostatin signaling may be considered to intervene in female patients with advanced heart failure".

scientific article published in November 2017

Reply: Cardiovascular function and exercise capacity in patients with colorectal cancer: does anticancer therapy matter?

scientific article published on 01 April 2015

Repurposing of approved cardiovascular drugs

scientific article

Resting heart rate is an independent predictor of death in patients with colorectal, pancreatic, and non-small cell lung cancer: results of a prospective cardiovascular long-term study

scientific article published in December 2016

Role of microRNAs in wasting in heart failure

scientific article published on 3 August 2017

Rosiglitazone reduces body wasting and improves survival in a rat model of cancer cachexia

scientific article published on 14 December 2013

Sarcopenia and Endothelial Function in Patients With Chronic Heart Failure: Results From the Studies Investigating Comorbidities Aggravating Heart Failure (SICA-HF).

scientific article published on 2 November 2016

Sarcopenia, cachexia, and muscle performance in heart failure: Review update 2016.

scientific article

Significance of animal models of cardiac cachexia and impact of gender on cardiac cachexia

scientific article published on 20 August 2016

Simvastatin reduces wasting and improves cardiac function as well as outcome in experimental cancer cachexia

scientific article published on 13 May 2013

Single-nucleotide polymorphisms in cachexia-related genes: Can they optimize the treatment of cancer cachexia?

scientific article published on June 2017

Six1 is down-regulated in end-stage human dilated cardiomyopathy independently of Ezh2.

scientific article published on December 2014

Skeletal muscle wasting in chronic heart failure

article

Studies on bacterial endotoxin and intestinal absorption function in patients with chronic heart failure

scientific article published on 28 December 2010

TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy

scientific article published on 27 January 2013

Tandospirone reduces wasting and improves cardiac function in experimental cancer cachexia

scientific article published on 12 October 2013

The 10th year of the Journal of Cachexia, Sarcopenia and Muscle

scientific article published on 01 December 2020

The anabolic catabolic transforming agent (ACTA) espindolol increases muscle mass and decreases fat mass in old rats

scientific article

The cholesterol paradox revisited: heart failure, systemic inflammation, and beyond

scientific article published in April 2008

The concept that focuses on oral motor and feeding function in cancer patients with muscle wasting: Skeletal muscle mass is associated with severe dysphagia in cancer patients

scientific article published on 2 May 2016

The impact of iron deficiency and anaemia on exercise capacity and outcomes in patients with chronic heart failure. Results from the Studies Investigating Co-morbidities Aggravating Heart Failure

scientific article published on 2 December 2015

The influence of age and sex on disease development in a novel animal model of cardiac cachexia

scientific article published on 25 February 2009

The need for a standardized definition for cachexia in chronic illness

scientific article

The role of myostatin in muscle wasting: an overview

scientific article

The underestimated impact of cachexia ⬇️

scientific article published on January 1, 2010

The xanthine oxidase inhibitor oxypurinol reduces cancer cachexia-induced cardiomyopathy

scientific article published on 14 June 2013

Theophylline is able to partially revert cachexia in tumour-bearing rats.

scientific article published on 21 August 2012

Therapeutic considerations of sarcopenia in heart failure patients

scientific article

Treatment of Muscle Wasting: An Overview of Promising Treatment Targets

scientific article published in December 2015

Treatment of pulmonary hypertension: bench to bedside

scientific article published in October 2011

Uric acid and xanthine oxidase in heart failure - Emerging data and therapeutic implications

scientific article

Uric acid in chronic heart failure--current pathophysiological concepts

scientific article published on 13 November 2008

Ursodeoxycholic acid in patients with chronic heart failure: a double-blind, randomized, placebo-controlled, crossover trial

scientific article published in February 2012

Ursodeoxycholic acid treatment in a rat model of cancer cachexia

scientific article published on 21 October 2011

Vagal nerve stimulation in chronic heart failure: an antiinflammatory intervention?

scientific article published on 01 July 2004

List of works by Jochen Springer

ACE Inhibitors and Sarcopenia: Covering All the BASEs?

Acylated ghrelin treatment normalizes skeletal muscle mitochondrial oxidative capacity and AKT phosphorylation in rat chronic heart failure

Adiponectin resistance in heart failure and the emerging pattern of metabolic failure in chronic heart failure

Advances in cachexia and sarcopenia research in the heart failure context: call for action

Animal models of cachexia and sarcopenia in chronic illness: Cardiac function, body composition changes and therapeutic results

Atrial natriuretic peptide and related peptides

Bile acids for cachexia therapy : Reply to the letter by Shailendra Kapoor: Ursodeoxycholic acid and its emerging role in attenuation of tumor growth in gastrointestinal malignancies

Biomarkers for cancer cachexia: where do we stand?

Biomarkers for chronic heart failure.

Blocking myostatin: muscle mass equals muscle strength?

Body weight changes and incidence of cachexia after stroke

Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?!

Cachexia in chronic heart failure: prognostic implications and novel therapeutic approaches

Cachexia in heart disease: highlights from the ESC 2010

Cachexia research in Japan: facts and numbers on prevalence, incidence and clinical impact

Cardiac cachexia: a systematic overview

Cardiac cachexia: hic et nunc

Cardiac cachexia: hic et nunc: "hic et nunc" - here and now.

Cardiac expression of neutrophil gelatinase-associated lipocalin in a model of cancer cachexia-induced cardiomyopathy

Cardiac muscle wasting in individuals with cancer cachexia

Cardiovascular function and predictors of exercise capacity in patients with colorectal cancer

Catabolic signaling and muscle wasting after acute ischemic stroke in mice: indication for a stroke-specific sarcopenia

Clinical perspective for wasting in diaphragm, an ever-trained muscle

Clinical problems of patients with cachexia due to chronic illness: a congress report

Comparison of sarcopenia and cachexia in men with chronic heart failure: results from the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF)

Concern regarding quality and quality of muscle

Considering technique of assessment and method for normalizing skeletal muscle mass

Detection of muscle wasting in patients with chronic heart failure using C-terminal agrin fragment: results from the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF).

Developing models for cachexia and their implications in drug discovery

Effect of application route of the ghrelin analog BIM-28131 (RM-131) on body weight and body composition in a rat heart failure model

Effect of ghrelin and its analogues, BIM‐28131 and BIM‐28125, on the expression of myostatin in a rat heart failure model ⬇️

Energy metabolism in human renin-gene transgenic rats: does renin contribute to obesity?

Erythropoietin improves cardiac wasting and outcomes in a rat model of liver cancer cachexia

Febuxostat improves outcome in a rat model of cancer cachexia

Formoterol in the treatment of experimental cancer cachexia: effects on heart function

Furosemide induces mortality in a rat model of chronic heart failure

Ghrelin and its analogues, BIM-28131 and BIM-28125, improve body weight and regulate the expression of MuRF-1 and MAFbx in a rat heart failure model

Growth differentiation factor-15 as a prognostic biomarker in cancer patients

Heart failure epidemiology and novel treatments in Japan: facts and numbers

Highlights of mechanistic and therapeutic cachexia and sarcopenia research 2010 to 2012 and their relevance for cardiology.

Highlights of the mechanistic and therapeutic cachexia and sarcopenia research 2010 to 2012 and their relevance for cardiology

Hypermetabolism: should cancer types, pathological stages and races be considered in assessing metabolism and could elevated resting energy expenditure be the therapeutic target in patients with advanced cancer?

IGF-1 treatment reduces weight loss and improves outcome in a rat model of cancer cachexia

Impact of Plasma Kynurenine Level on Functional Capacity and Outcome in Heart Failure - Results From Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF).

In vivomodels of cardiac diseases: application to drug development and screening ⬇️

Influence of cancer cachexia on drug liver metabolism and renal elimination in rats

Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia

Insulin resistance in heart failure: differences between patients with reduced and preserved left ventricular ejection fraction

Irisin - a myokine potentially bridging muscle and fat tissue in cachexia

Is cardiac wasting accompanied by skeletal muscle loss in breast cancer patients receiving anticancer treatment?

Leukocyte redistribution: effects of beta blockers in patients with chronic heart failure

Lipopolysaccharide responsiveness is an independent predictor of death in patients with chronic heart failure

Liquid chromatography-tandem mass spectrometry method for simultaneous quantification of bisoprolol, ramiprilat, propranolol and midazolam in rat dried blood spots

Liver metabolism in cardiac cachexia ⬇️

MT-102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia

Mechanism and novel therapeutic approaches to wasting in chronic disease

Megestrol acetate improves cardiac function in a model of cancer cachexia-induced cardiomyopathy by autophagic modulation

MicroRNAs in muscle wasting

Molecular mechanisms and treatment targets of muscle wasting and cachexia in heart failure: an overview

Muscle Wasting and Sarcopenia in Heart Failure-The Current State of Science

Muscle wasting and cachexia in heart failure: mechanisms and therapies

Muscle wasting and sarcopenia in heart failure and beyond: update 2017.

Muscle wasting in cardiac cachexia

Muscle wasting in heart failure: An overview

Muscle wasting: an overview of recent developments in basic research

Muscle wasting: an overview of recent developments in basic research

Myostatin signaling is up-regulated in female patients with advanced heart failure

Myostatin: Regulator of muscle wasting in heart failure and treatment target for cardiac cachexia.

Neuromuscular electrical stimulation for muscle wasting in heart failure patients

No effects of human ghrelin on cardiac function despite profound effects on body composition in a rat model of heart failure

Novel mechanism of ghrelin therapy for cachexia

Novel treatment approaches to cachexia and sarcopenia: highlights from the 5th Cachexia Conference

Nutrition in cachexia: from bench to bedside

Overweight and obesity are associated with improved survival, functional outcome, and stroke recurrence after acute stroke or transient ischaemic attack: observations from the TEMPiS trial ⬇️

Pharmacokinetics of drugs in cachectic patients: a systematic review

Physical activity for the prevention and treatment of sarcopenic obesity

Preserved Skeletal Muscle Mitochondrial Function, Redox State, Inflammation and Mass in Obese Mice with Chronic Heart Failure

Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

Procalcitonin-guided antibiotic treatment in heart failure

Impact of Plasma Kynurenine Level on Functional Capacity and Outcome in Heart Failure　- Results From Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF).