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List of works by Bernd Gruhn

A pediatric prognostic score for patients undergoing allogeneic hematopoietic stem cell transplantation

scientific article

ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia

scientific article

Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT.

scientific article published on 23 January 2015

Allogeneic hematopoietic stem cell transplantation from unrelated donors is associated with higher infection rates in children with acute lymphoblastic leukemia-A prospective international multicenter trial on behalf of the BFM-SG and the EBMT-PDWP

scientific article published on 29 May 2019

Allogeneic stem cell transplantation for acquired pure red cell aplasia

scientific article published on 09 September 2019

Are MTT assays the right tool to analyze drug resistance caused by ABC-transporters in patient samples?

scientific article published in September 2005

B cell depletion for autoimmune diseases in paediatric patients

scientific article

Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

scientific article published on 07 December 2018

CTLA-4 polymorphism rs231775: Influence on relapse and survival after allogeneic hematopoietic stem cell transplantation in childhood

scientific article published on 07 January 2019

CTLA-4 polymorphisms: influence on transplant-related mortality and survival in children undergoing allogeneic hematopoietic stem cell transplantation.

scientific article published on 15 January 2018

Childhood acute myelogenous leukaemia: association between PRAME, apoptosis- and MDR-related gene expression

scientific article published on 15 September 2006

Children with myelodysplastic syndrome (MDS) and increasing mixed chimaerism after allogeneic stem cell transplantation have a poor outcome which can be improved by pre-emptive immunotherapy

scientific article published on 01 March 2005

Chronic cutaneous graft-versus-host disease in two children responds to UVA1 therapy: improvement of skin lesions, joint mobility, and quality of life.

scientific article published in August 2004

Clinical implications of PRAME gene expression in childhood acute myeloid leukemia

scientific article (publication date: March 2002)

Coexpression of Multiple ABC-Transporters is Strongly Associated with Treatment Response in Childhood Acute Myeloid Leukemia

scientific article published on 29 October 2015

Comparison of a LightCycler-based real-time PCR for quantitation of Epstein-Barr viral load in different clinical specimens with semiquantitative PCR.

scientific article published on May 2006

Comparison of different rabbit ATG preparation effects on early lymphocyte subset recovery after allogeneic HSCT and its association with EBV-mediated PTLD.

scientific article published on 25 June 2014

Continuous molecular remission and regression of side effects after discontinuation of salvage therapy with sorafenib and donor lymphocyte infusions in a young patient with relapsed AML

scientific article published on 16 March 2016

Correction: Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial

scientific article published on 25 November 2019

Cytotoxicity of dimethylacetamide and pharmacokinetics in children receiving intravenous busulfan

scientific article published on May 2007

Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial

scientific article published on 23 February 2012

Detection of relapse after hematopoietic stem cell transplantation in childhood by monitoring of WT1 expression and chimerism.

scientific article

Development of hypertension is less frequent after bilateral nephron sparing surgery for bilateral Wilms tumor in a long-term survey.

scientific article published on 7 August 2014

EBV load in whole blood correlates with LMP2 gene expression after pediatric heart transplantation or allogeneic hematopoietic stem cell transplantation

scientific article published on May 2014

EZH2 mutations and promoter hypermethylation in childhood acute lymphoblastic leukemia.

scientific article

Electrical impedance scanning?application of this new technique for lymph node evaluation in children ⬇️

scientific article published on 01 May 2003

Evaluating STAT5 Phosphorylation as a Mean to Assess T Cell Proliferation

article by Michael Bitar et al published 5 April 2019 in Frontiers in Immunology

Evaluation of Three Commercial Varicella-Zoster Virus IgG Enzyme-Linked Immunosorbent Assays in Comparison to the Fluorescent-Antibody-to-Membrane-Antigen Test ⬇️

scientific article published on June 20, 2012

Extended Treatment With Mesenchymal Stromal Cells-Frankfurt am Main (MSC-FFM, Obnitix) in a Pediatric Patient With Steroid-refractory Acute Gastrointestinal Graft-Versus-Host Disease (GVHD): Case Report and Review of the Literature

scientific article published on 28 February 2020

Favorable outcomes of hematopoietic stem cell transplantation in children and adolescents with Diamond-Blackfan anemia

scientific article published on 01 April 2020

Flow cytometry as a diagnostic tool for hereditary spherocytosis

scientific article published in January 2006

Frequent ASXL1 mutations in children and young adults with chronic myeloid leukemia

scientific article published on 13 June 2018

Gemtuzumab ozogamicin in children with relapsed or refractory acute myeloid leukemia: a report by Berlin-Frankfurt-Münster study group

scholarly article by Naghmeh Niktoreh et al published January 2019 in Haematologica

Gonadal Function after Busulfan Compared with Treosulfan in Children and Adolescents Undergoing Allogeneic Hematopoietic Stem Cell Transplant

scientific article published on 11 May 2019

Haploidentical Stem Cell Transplantation for Refractory/Relapsed Neuroblastoma.

scientific article published on 4 January 2018

Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial

scientific article published on 02 October 2019

Hematopoietic stem-cell transplantation for advanced systemic mastocytosis

scientific article

Heparanase polymorphisms: influence on incidence of hepatic sinusoidal obstruction syndrome in children undergoing allogeneic hematopoietic stem cell transplantation.

scientific article

High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia.

scientific article published on 30 June 2015

Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemia

scientific article published on April 2006

Identification of miRNAs and associated pathways regulated by Leukemia Inhibitory Factor in trophoblastic cell lines

scientific article published on 12 September 2019

Immunosuppressive Total Nodal Irradiation-Based Reconditioning Regimens After Graft Rejection or Graft Failure in Pediatric Patients Treated With Myeloablative Allogeneic Hematopoietic Cell Transplantation

scientific article published on 26 December 2018

Impact of chemotherapy for childhood leukemia on brain morphology and function

scientific article

In acute leukemia, the polymorphism −211C>T in the promoter region of the multidrug resistance-associated protein 3 (MRP3) does not determine the expression level of the gene

article

Increased activity of histone deacetylases in childhood acute lymphoblastic leukaemia and acute myeloid leukaemia: support for histone deacetylase inhibitors as antileukaemic agents ⬇️

scientific article published on June 12, 2012

Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell transplantation: possible role for pre-emptive immunotherapy?

scientific article

Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

scientific article published on 28 February 2011

Long term survival in children with acute leukaemia and complications requiring mechanical ventilation

scientific article

Low incidence of symptomatic osteonecrosis after allogeneic HSCT in children with high-risk or relapsed ALL - results of the ALL-SCT 2003 trial

scientific article published on 20 July 2018

MLLT10 and IL3 rearrangement together with a complex four-way translocation and trisomy 4 in a patient with early T-cell precursor acute lymphoblastic leukemia: A case report

scientific article published on 25 November 2014

Mesothelin, a possible target for immunotherapy, is expressed in primary AML cells

scientific article

Minimal residual disease prior to allogeneic hematopoietic cell transplantation in acute myeloid leukemia: a meta-analysis

scientific article

Molecular remission using three monoclonal antibodies followed by allogeneic bone marrow transplantation in an infant with refractory ALL

scientific article published on 18 February 2020

Monitoring of Epstein-Barr virus load after hematopoietic stem cell transplantation for early intervention in post-transplant lymphoproliferative disease

scientific article published in March 2008

Monitoring of hematopoietic chimerism after transplantation for pediatric myelodysplastic syndrome: real-time or conventional short tandem repeat PCR in peripheral blood or bone marrow?

scientific article published on 31 July 2014

Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency

scientific article

NOD2/CARD15 gene polymorphisms affect outcome in pediatric allogeneic stem cell transplantation

scientific article published on 01 July 2011

PRAME expression is not associated with down-regulation of retinoic acid signaling in primary acute myeloid leukemia

scientific article

PRAME gene expression in childhood acute lymphoblastic leukemia

scientific article (publication date: October 2002)

Pharmacokinetics and safety of gadobutrol-enhanced magnetic resonance imaging in pediatric patients

scientific article published on December 2009

Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia

scientific article published on 10 December 2019

Pneumococcal conjugate vaccine provides early protective antibody responses in children after related and unrelated allogeneic hematopoietic stem cell transplantation

scientific article published on 7 November 2006

Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in children

scientific article

Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia

scientific article

Population pharmacokinetics of oral busulfan in children

scientific article published on 17 June 2003

Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation

scientific article published on 26 September 2011

Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL

scientific article published on 14 May 2019

Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders

scientific article published on 26 May 2020

Prevalence of BK virus subtype I in Germany

scientific article

Prognostic impact of WT1 expression prior to hematopoietic stem cell transplantation in children with malignant hematological diseases

scientific article published on 20 September 2014

Prospective validation of a new method of monitoring minimal residual disease in childhood acute myelogenous leukemia

scientific article published on 11 December 2014

Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL.

scientific article published on 22 September 2017

Recent developments in the prevention and treatment of Epstein–Barr virus-associated lymphoproliferative diseases ⬇️

scientific article published on April 1, 2004

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

scientific article published on 23 October 2013

Risk assessment of relapse by lineage-specific monitoring of chimerism in children undergoing allogeneic stem cell transplantation for acute lymphoblastic leukemia

scientific article published on 11 February 2016

Risk factors for mixed chimerism in children with hemophagocytic lymphohistiocytosis after reduced toxicity conditioning

scientific article published on 03 July 2020

Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party

scientific article

Solid organ transplantation after hematopoietic stem cell transplantation in childhood: A multicentric retrospective survey

scientific article published on 25 January 2019

Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML

scientific article published on 11 January 2012

Stem-cell transplantation in children with acute lymphoblastic leukemia: A prospective international multicenter trial comparing sibling donors with matched unrelated donors-The ALL-SCT-BFM-2003 trial

scientific article published on 9 March 2015

Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure

scientific article published on 15 January 2007

Superior outcome using cyclosporin A alone versus cyclosporin A plus methotrexate for post-transplant immunosuppression in children with acute leukemia undergoing sibling hematopoietic stem cell transplantation

scientific article published on 06 December 2014

Supportive mistletoe therapy in a patient with metastasised neuroblastoma

Surgical Implications for Diagnosis and Treatment of Intestinal Aspergillosis in Pediatric Patients with ALL.

scientific article published on 25 September 2017

Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis

scientific article published on 01 May 2020

The expression of histone deacetylase 4 is associated with prednisone poor-response in childhood acute lymphoblastic leukemia

scientific article published on 12 August 2013

The impact of the methotrexate administration schedule and dose in the treatment of children and adolescents with B-cell neoplasms: a report of the BFM Group Study NHL-BFM95.

scientific article

The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis

scientific article published on 20 April 2016

The multidrug resistance-associated protein 3 (MRP3) is associated with a poor outcome in childhood ALL and may account for the worse prognosis in male patients and T-cell immunophenotype

scientific article published on 19 June 2003

Therapy with low-dose azacitidine for MDS in children and young adults: a retrospective analysis of the EWOG-MDS study group.

scientific article

Toll-Like 4 Receptor Variant, Asp299Gly, and Reduced Risk of Hemorrhagic Cystitis after Hematopoietic Stem Cell Transplantation

Toxicity and pharmacokinetics of i.v. busulfan in children before stem cell transplantation

scientific article published in March 2005

Transplantation of CD3/CD19 depleted allografts from haploidentical family donors in paediatric leukaemia

scientific article published on 4 March 2014

Treatment of a patient with chronic immune thrombocytopenic purpura with rituximab and monitoring by flow cytometric analysis

scientific article

Treatment of extensive chronic cutaneous graft-versus-host disease in an infant with topical pimecrolimus

scientific article

Treatment of graft failure with TNI-based reconditioning and haploidentical stem cells in paediatric patients.

scientific article published on 24 June 2016

Treosulfan-based conditioning regimen for children and adolescents with hemophagocytic lymphohistiocytosis

scientific article

Treosulfan-fludarabine-thiotepa-based conditioning treatment before allogeneic hematopoietic stem cell transplantation for pediatric patients with hematological malignancies

scientific article published on 20 March 2020

Viruses and atypical bacteria in the respiratory tract of immunocompromised and immunocompetent patients with airway infection

scientific article published on 27 May 2020

Wilms tumor gene single nucleotide polymorphism rs16754 predicts a favorable outcome in children with acute lymphoblastic leukemia

scientific article published on 30 July 2015

X-linked protoporphyria: Iron supplementation improves protoporphyrin overload, liver damage and anaemia

scientific article published on 20 July 2015

Yoga in school sports improves functioning of autonomic nervous system in young adults: A non-randomized controlled pilot study

scientific article published on 13 April 2020

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