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List of works by Bernd Gruhn

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The impact of the methotrexate administration schedule and dose in the treatment of children and adolescents with B-cell neoplasms: a report of the BFM Group Study NHL-BFM95.

scientific article
Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial

scientific article published on 23 February 2012
Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell transplantation: possible role for pre-emptive immunotherapy?

scientific article
Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

scientific article published on 23 October 2013
Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party

scientific article
Hematopoietic stem-cell transplantation for advanced systemic mastocytosis

scientific article
Stem-cell transplantation in children with acute lymphoblastic leukemia: A prospective international multicenter trial comparing sibling donors with matched unrelated donors-The ALL-SCT-BFM-2003 trial

scientific article published on 9 March 2015
Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation

scientific article published on 26 September 2011
Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT

scientific article published on January 23, 2015
Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemia

scientific article published on April 2006
Pneumococcal conjugate vaccine provides early protective antibody responses in children after related and unrelated allogeneic hematopoietic stem cell transplantation

scientific article published on 7 November 2006
Transplantation of CD3/CD19 depleted allografts from haploidentical family donors in paediatric leukaemia

scientific article published on 4 March 2014
Clinical implications of PRAME gene expression in childhood acute myeloid leukemia

scientific article (publication date: March 2002)
Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency

scientific article
Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure

scientific article published on 15 January 2007
ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia

scientific article published in July 2006
The multidrug resistance-associated protein 3 (MRP3) is associated with a poor outcome in childhood ALL and may account for the worse prognosis in male patients and T-cell immunophenotype

scientific article published on 19 June 2003
Minimal residual disease prior to allogeneic hematopoietic cell transplantation in acute myeloid leukemia: a meta-analysis

scientific article
Monitoring of Epstein-Barr virus load after hematopoietic stem cell transplantation for early intervention in post-transplant lymphoproliferative disease

scientific article published in March 2008
Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

scientific article published on 28 February 2011
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML

scientific article published on 11 January 2012
Prevalence of BK virus subtype I in Germany

scientific article
Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in children

scientific article
Impact of chemotherapy for childhood leukemia on brain morphology and function

scientific article
The expression of histone deacetylase 4 is associated with prednisone poor-response in childhood acute lymphoblastic leukemia

scientific article published on August 12, 2013
Pharmacokinetics and safety of gadobutrol-enhanced magnetic resonance imaging in pediatric patients

scientific article published on December 2009
PRAME gene expression in childhood acute lymphoblastic leukemia

scientific article (publication date: October 2002)
Prospective validation of a new method of monitoring minimal residual disease in childhood acute myelogenous leukemia

scientific article published on 11 December 2014
Population pharmacokinetics of oral busulfan in children

scientific article published on 17 June 2003
Evaluation of Three Commercial Varicella-Zoster Virus IgG Enzyme-Linked Immunosorbent Assays in Comparison to the Fluorescent-Antibody-to-Membrane-Antigen Test

scientific article published on June 20, 2012
Treosulfan-based conditioning regimen for children and adolescents with hemophagocytic lymphohistiocytosis

scientific article
The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis

scientific article published on 20 April 2016
B cell depletion for autoimmune diseases in paediatric patients

scientific article
Mesothelin, a possible target for immunotherapy, is expressed in primary AML cells

scientific article
Coexpression of Multiple ABC-Transporters is Strongly Associated with Treatment Response in Childhood Acute Myeloid Leukemia

scientific article published on 29 October 2015
Cytotoxicity of dimethylacetamide and pharmacokinetics in children receiving intravenous busulfan

scientific article published on May 2007
Flow cytometry as a diagnostic tool for hereditary spherocytosis

scientific article published in January 2006
Toxicity and pharmacokinetics of i.v. busulfan in children before stem cell transplantation

scientific article published in March 2005
Development of hypertension is less frequent after bilateral nephron sparing surgery for bilateral Wilms tumor in a long-term survey

scientific article published on 7 August 2014
Therapy with low-dose azacitidine for MDS in children and young adults: a retrospective analysis of the EWOG-MDS study group.

scientific article
EZH2 mutations and promoter hypermethylation in childhood acute lymphoblastic leukemia

scientific article
Treatment of extensive chronic cutaneous graft-versus-host disease in an infant with topical pimecrolimus

scientific article
Heparanase polymorphisms: influence on incidence of hepatic sinusoidal obstruction syndrome in children undergoing allogeneic hematopoietic stem cell transplantation

scientific article published on October 22, 2014
PRAME expression is not associated with down-regulation of retinoic acid signaling in primary acute myeloid leukemia

scientific article published in August 2007
Children with myelodysplastic syndrome (MDS) and increasing mixed chimaerism after allogeneic stem cell transplantation have a poor outcome which can be improved by pre-emptive immunotherapy

scientific article published on 01 March 2005
X‐linked protoporphyria: Iron supplementation improves protoporphyrin overload, liver damage and anaemia

scientific article published on July 20, 2015
Chronic cutaneous graft-versus-host disease in two children responds to UVA1 therapy: improvement of skin lesions, joint mobility, and quality of life

scientific article published in August 2004
Prognostic impact of WT1 expression prior to hematopoietic stem cell transplantation in children with malignant hematological diseases

scientific article published on September 20, 2014
Childhood acute myelogenous leukaemia: association between PRAME, apoptosis- and MDR-related gene expression

scientific article published on 15 September 2006
Increased activity of histone deacetylases in childhood acute lymphoblastic leukaemia and acute myeloid leukaemia: support for histone deacetylase inhibitors as antileukaemic agents

scientific article published on June 12, 2012

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