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List of works by Simon M Cool

A genomic biomarker that identifies human bone marrow-derived mesenchymal stem cells with high scalability

scientific article published on 08 June 2020

Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2)

scientific article

Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility ⬇️

scientific article

Comparative Assessment of the Effects of Gender-specific Heparan Sulfates on Mesenchymal Stem Cells ⬇️

scientific article published on March 25, 2011

Concise Review: Multifaceted Characterization of Human Mesenchymal Stem Cells for Use in Regenerative Medicine.

scientific article published on 26 October 2017

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.

scientific article

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria ⬇️

scientific article published on September 14, 2010

Glycosaminoglycans modulate RANKL-induced osteoclastogenesis

scientific article

Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrow

scientific article

Heparan sulfate mediates the proliferation and differentiation of rat mesenchymal stem cells

scientific journal article

Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity

scientific article

Heparan sulfate regulates the anabolic activity of MC3T3-E1 preosteoblast cells by induction of Runx2.

scientific article published on January 2007

High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells.

scientific article

Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2

scientific article published on 9 June 2012

Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production

scientific article published on 11 August 2016

In Reply

scientific article published on 20 August 2020

Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2

scientific article published on 24 April 2020

Loss of CHSY1, a Secreted FRINGE Enzyme, Causes Syndromic Brachydactyly in Humans via Increased NOTCH Signaling ⬇️

scientific article published on December 10, 2010

MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma

scientific article published on 29 May 2013

Osteogenic Stimulation of Human Adipose-Derived Mesenchymal Stem Cells Using a Fungal Metabolite That Suppresses the Polycomb Group Protein EZH2.

scientific article published on 27 December 2017

Porcine bone marrow stromal cell differentiation on heparin-adsorbed poly(e-caprolactone)-tricalcium phosphate-collagen scaffolds.

scientific article

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

scientific article published on December 2009

Sulfated glycosaminoglycans mediate the effects of FGF2 on the osteogenic potential of rat calvarial osteoprogenitor cells

scientific journal article

Sustained release and osteogenic potential of heparan sulfate-doped fibrin glue scaffolds within a rat cranial model.

scientific article published on 12 September 2007

Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway

scientific article

The Effect of Human Bone Marrow Stroma-Derived Heparan Sulfate on the Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem Cells ⬇️

scientific article published on December 24, 2010

The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesis.

scientific article published on September 2009

The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts

scientific article

The synovial microenvironment of osteoarthritic joints alters RNA-seq expression profiles of human primary articular chondrocytes

scientific article published on July 2016

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