List of works - Adam Golebiowski

2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors

scientific article

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase

scientific article published on 24 April 2020

Boronic acid-based arginase inhibitors in cancer immunotherapy

scientific article published on 23 July 2020

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases

scientific article published on 23 July 2019

Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2

scientific article published on 24 April 2006

Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1

scientific article published on 02 May 2006

Development of N-4,6-pyrimidine-N-alkyl-N'-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase

scientific article published on 08 May 2006

Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3).

scientific article published on 9 December 2006

Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production

scientific article

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors

scientific article published on 13 March 2020

Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury

scientific article

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis

scientific article published on 20 October 2020

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase

scientific article published on 22 December 2017

Lead compounds discovered from libraries: part 2.

scientific article

Solid-supported synthesis of putative peptide beta-turn mimetics via Ugi reaction for diketopiperazine formation

scientific article

Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction

scientific article

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

scientific article published on 28 December 2017

The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

scientific article published on 25 September 2006

The development of monocyclic pyrazolone based cytokine synthesis inhibitors

scientific article

The development of new bicyclic pyrazole-based cytokine synthesis inhibitors

scientific article published in October 2004

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production

scientific article

The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck)

scientific article published on 06 June 2006

The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production

scientific article published on 5 June 2006

The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones

scientific article

The synthesis and evaluation of indolylureas as PKCα inhibitors

scientific article published on 26 February 2011

List of works by Adam Golebiowski

2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase

Boronic acid-based arginase inhibitors in cancer immunotherapy

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases

Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2

Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1

Development of N-4,6-pyrimidine-N-alkyl-N'-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase

Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3).

Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors

Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase

Lead compounds discovered from libraries: part 2.

Solid-supported synthesis of putative peptide beta-turn mimetics via Ugi reaction for diketopiperazine formation

Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

The development of monocyclic pyrazolone based cytokine synthesis inhibitors

The development of new bicyclic pyrazole-based cytokine synthesis inhibitors

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production

The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck)

The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production

The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones

The synthesis and evaluation of indolylureas as PKCα inhibitors