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List of works by Timothy M Willson

A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation

scientific article published on 20 November 2020

A new, highly selective murine peroxisome proliferator-activated receptor δ agonist increases responsiveness to thermogenic stimuli and glucose uptake in skeletal muscle in obese mice ⬇️

scientific article published on January 27, 2011

Activation of the orphan receptor RIP14 by retinoids ⬇️

scientific article published on July 22, 1997

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway ⬇️

scientific article published on January 9, 1998

Cloning and Characterization of Human Estrogen Receptor β Isoforms ⬇️

scientific article published on June 9, 1998

Comprehensive characterization of the Published Kinase Inhibitor Set

scientific article

Dissection of the Molecular Mechanism of Action of GW5638, a Novel Estrogen Receptor Ligand, Provides Insights into the Role of Estrogen Receptor in Bone* ⬇️

scientific article published on 01 September 1997

Erratum: Corrigendum: The promise and peril of chemical probes

scientific article published in November 2015

GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbα ⬇️

scientific article published on October 15, 2010

Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor

scientific article published on 10 July 2019

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase.

scientific article

Identification of a series of PPARγ/δ dual agonists via solid-Phase parallel synthesis ⬇️

scientific article published on November 19, 2001

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ ⬇️

scientific article published on September 10, 1998

Ligand-Dependent Regulation of the Activity of the Orphan Nuclear Receptor, Small Heterodimer Partner (SHP), in the Repression of Bile Acid BiosyntheticCYP7A1andCYP8B1Genes ⬇️

scientific article published on May 12, 2011

Optimization of 3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines as Potent, Orally Active CCK-A Agonists ⬇️

scientific article published on August 15, 1997

Peroxisome proliferator-activated receptor agonists ⬇️

scientific article published on August 1, 1997

Probing the Structure and Function of the Estrogen Receptor Ligand Binding Domain by Analysis of Mutants with Altered Transactivation Characteristics ⬇️

scientific article published on August 1, 1997

Quantifying CDK inhibitor selectivity in live cells

scientific article published on 02 June 2020

Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor ⬇️

scientific article published on November 12, 2001

SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK)

scientific article published on 26 February 2019

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors ⬇️

scientific article published on November 6, 2001

Synthesis and biological activity of l-tyrosine-based PPARγ agonists with reduced molecular weight ⬇️

scientific article published on December 17, 2001

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions ⬇️

scientific article published on September 1, 1998

The importance of chronobiology to drug discovery ⬇️

scientific article published on 02 June 2012

The nuclear receptor PPARγ-bigger than fat ⬇️

scientific article published on 01 October 1998

The promise and peril of chemical probes

scientific article

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