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List of works by Betsy C Herold

619. Intestinal Microbiome Changes Associated with Immune Status and Clostridium difficile Colonization in Hospitalized Children

A Multicenter Consortium to Define the Epidemiology and Outcomes of Inpatient Respiratory Viral Infections in Pediatric Hematopoietic Stem Cell Transplant Recipients.

scientific article published in July 2017

A Multicenter Consortium to Define the Epidemiology and Outcomes of Pediatric Solid Organ Transplant Recipients With Inpatient Respiratory Virus Infection

scientific article published on 10 March 2018

A Perspective on Progress and Gaps in HIV Prevention Science ⬇️

scientific article published on November 1, 2012

A compartmental pharmacokinetic evaluation of long-acting rilpivirine in HIV-negative volunteers for pre-exposure prophylaxis.

scientific article published on 26 May 2014

A comprehensive murine model to evaluate topical vaginal microbicides: mucosal inflammation and susceptibility to genital herpes as surrogate markers of safety

scientific article published on 19 March 2007

A hybrid strategy for the prevention of cytomegalovirus-related complications in pediatric liver transplantation recipients.

scientific article published in May 2009

A multicenter study to define the epidemiology and outcomes of Clostridioides difficile infection in pediatric hematopoietic cell and solid organ transplant recipients

scientific article published on 16 February 2020

A phase 1 randomized placebo-controlled safety and pharmacokinetic trial of a tenofovir disoproxil fumarate vaginal ring.

scientific article published on 24 November 2015

A phase I randomized safety study of a single-size silicone rubber diaphragm used with or without a lactic-acid-containing diaphragm gel

scientific article published on 21 August 2019

A pilot program to evaluate deceased donor disease transmission risk: the New York Organ Donor Network Infectious Disease Working Group

scientific article published on October 2014

A prospective, comparative study of the immune response to inactivated influenza vaccine in pediatric liver transplant recipients and their healthy siblings

scientific article

A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel.

scientific article

A single-cycle glycoprotein D deletion viral vaccine candidate, ΔgD-2, elicits polyfunctional antibodies that protect against ocular herpes simplex virus

scientific article published on 15 April 2020

ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations

scientific article published on 16 August 2006

Access to nectin favors herpes simplex virus infection at the apical surface of polarized human epithelial cells

scientific article

Adenovirus infection in pediatric small bowel transplantation recipients

scientific article published in July 2003

Altered biomarkers of mucosal immunity and reduced vaginal Lactobacillus concentrations in sexually active female adolescents

scientific article

Amphipathic DNA polymers are candidate vaginal microbicides and block herpes simplex virus binding, entry and viral gene expression.

scientific article published on January 2007

An HSV-2 single-cycle candidate vaccine deleted in glycoprotein D, ΔgD-2, protects male mice from lethal skin challenge with clinical isolates of HSV-1 and HSV-2.

scientific article published on 5 December 2017

An innate antiviral pathway acting before interferons at epithelial surfaces

scientific article

Antiviral activity of genital tract secretions after oral or topical tenofovir pre-exposure prophylaxis for HIV-1.

scientific article published on May 2014

Antiviral agents for herpes viruses ⬇️

scientific article published on July 1, 1998

Assessment of adherence to product dosing in a pilot microbicide study.

scientific article published on December 2007

Association between herpes simplex virus-1 infection and idiopathic unilateral facial paralysis in children and adolescents

scientific article published in May 2008

Association of High-Risk Human Papillomavirus with Genital Tract Mucosal Immune Factors in HIV-Infected Women

scientific article

Association of bactericidal activity of genital tract secretions with Escherichia coli colonization in pregnancy

scientific article

Bacterial Vaginosis and Subclinical Markers of Genital Tract Inflammation and Mucosal Immunity

scientific article

Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study

scientific article published on 17 May 2008

Bridging the gap between preclinical and clinical microbicide trials: blind evaluation of candidate gels in murine models of efficacy and safety

scientific article

Bullous pemphigoid after liver transplantation for liver failure.

scientific article published in November 2006

Calicivirus enteritis in an intestinal transplant recipient

scientific article published on 01 June 2003

Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model

scientific article published on 23 April 2008

Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action.

scientific article

Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread

scientific article

Cervical intraepithelial neoplasia is associated with genital tract mucosal inflammation

scientific article published on August 2012

Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection

scientific article published on 13 October 2005

Changes in the soluble mucosal immune environment during genital herpes outbreaks

scientific article published on October 2012

Characterization of a BHK(TK-) cell clone resistant to postattachment entry by herpes simplex virus types 1 and 2 ⬇️

scientific article published on August 1, 1997

Characterization of an acyclovir-resistant herpes simplex virus type 2 strain isolated from a premature neonate.

scientific article published on 13 April 2000

Clinical Characteristics and Outcomes of Hospitalized and Critically Ill Children and Adolescents with Coronavirus Disease 2019 (COVID-19) at a Tertiary Care Medical Center in New York City

scientific article published on 11 May 2020

Clinical Vignettes: Donor-Derived Infections

scientific article published on 01 December 2018

Comparison of Follicular and Luteal Phase Mucosal Markers of HIV Susceptibility in Healthy Women

scientific article published on 10 January 2016

Comparison of Mucosal Markers of Human Immunodeficiency Virus Susceptibility in Healthy Premenopausal Versus Postmenopausal Women

scientific article published on 11 April 2017

Comparison of the vaginal microbial communities in women with recurrent genital HSV receiving acyclovir intravaginal rings

scientific article

Correction: Performance of Swabs, Lavage, and Diluents to Quantify Biomarkers of Female Genital Tract Soluble Mucosal Mediators.

scientific article published on 26 January 2012

Decreased vaginal disease in J-chain-deficient mice following herpes simplex type 2 genital infection.

scientific article published in May 2000

Diagnosis and management of community-associated MRSA infections in children

scientific article published on February 2010

Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy

scientific article

Differential Mechanisms of Tenofovir and Tenofovir Disoproxil Fumarate Cellular Transport and Implications for Topical Preexposure Prophylaxis.

scientific article published on 28 December 2015

Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety

scientific article

Dynamics of cell-mediated immune responses to cytomegalovirus in pediatric transplantation recipients

scientific article published on 18 July 2011

Dynasore disrupts trafficking of herpes simplex virus proteins

scientific article published on 15 April 2015

Effect of Epstein-Barr virus sequence variation on performance of the Roche real-time LightCycler PCR assay

scientific article published on 14 May 2008

Efficacy and safety of a new vaginal contraceptive antimicrobial formulation containing high molecular weight poly(sodium 4-styrenesulfonate).

scientific article published on April 2002

Efficacy of the Herpes Simplex Virus 2 (HSV-2) Glycoprotein D/AS04 Vaccine against Genital HSV-2 and HSV-1 Infection and Disease in the Cotton Rat Sigmodon hispidus Model.

scientific article

Evaluation of 3 approaches for assessing adherence to vaginal gel application in clinical trials

scientific article

Female genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections

scientific article

Female genital tract secretions inhibit herpes simplex virus infection: correlation with soluble mucosal immune mediators and impact of hormonal contraception.

scientific article published on 15 December 2009

Female genital tract shedding of HIV-1 is rare in women with suppressed HIV-1 in plasma

scientific article published on 01 January 2020

First case of toxoplasmosis following small bowel transplantation and systematic review of tissue-invasive toxoplasmosis following noncardiac solid organ transplantation

scientific article

Focal adhesion kinase plays a pivotal role in herpes simplex virus entry

scientific article published on July 2005

Generation of IL-3-Secreting CD4+ T Cells by Microbial Challenge at Skin and Mucosal Barriers

scientific article published on 16 May 2019

Genital herpes simplex virus type 2 infection in humanized HIV-transgenic mice triggers HIV shedding and is associated with greater neurological disease

scientific article published on 29 August 2013

Genital tract HIV RNA levels and their associations with human papillomavirus infection and risk of cervical precancer

scientific article

Glycoprotein B plays a predominant role in mediating herpes simplex virus type 2 attachment and is required for entry and cell-to-cell spread

scientific article published in September 2002

Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity ⬇️

scientific article published on March 1, 1991

Griffithsin protects mice from genital herpes by preventing cell-to-cell spread

scientific article published on 27 March 2013

HIV, sexual violence and special populations: adolescence and pregnancy

scientific article

HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression.

scientific article

HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target

scientific article

HSV-2 ΔgD elicits FcγR-effector antibodies that protect against clinical isolates

scientific article

HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses

scientific article published on 01 August 2020

Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease.

scientific article

Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergy

scientific article published on 14 November 2012

Herpes simplex virus as a model vector system for gene therapy in renal disease

scientific article

Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanism

scientific article published on 30 July 2008

Herpes simplex virus entry is associated with tyrosine phosphorylation of cellular proteins.

scientific article published on April 1999

Herpes simplex virus triggers activation of calcium-signaling pathways

scientific article

Herpes simplex virus type 2 glycoprotein H interacts with integrin αvβ3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells.

scientific article

Herpes simplex viruses activate phospholipid scramblase to redistribute phosphatidylserines and Akt to the outer leaflet of the plasma membrane and promote viral entry

scientific article published on 2 January 2018

Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection

scientific article published in December 2006

Humoral and cell-mediated immune responses to monovalent 2009 influenza A/H1N1 and seasonal trivalent influenza vaccines in high-risk children

scientific article

Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients

scientific article published on 21 September 2020

Immunization of pediatric solid-organ transplantation candidates: immunizations in transplant candidates

scientific article

Impact of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus Dual Infection on Female Genital Tract Mucosal Immunity and the Vaginal Microbiome

scientific article published on 01 July 2019

Impact of Sex on the Pharmacokinetics and Pharmacodynamics of 1% Tenofovir Gel

scientific article

Impact of microbicides and sexually transmitted infections on mucosal immunity in the female genital tract

scientific article published on November 2006

Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection

article

Impact of surveillance stool culture guided selection of antibiotics in the management of pediatric small bowel transplant recipients

scientific article

Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer system

scientific article

Innate Antibacterial Activity in Female Genital Tract Secretions Is Associated with Increased Risk of HIV Acquisition

scientific article

Interlaboratory reproducibility of female genital tract cytokine measurements by Luminex: implications for microbicide safety studies

scientific article

Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection

scientific article

Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges

scientific article published on 16 September 2013

Lactobacillus crispatus dominant vaginal microbiome is associated with inhibitory activity of female genital tract secretions against Escherichia coli

scientific article

Lactobacillus proteins are associated with the bactericidal activity against E. coli of female genital tract secretions

scientific article

Levels of Genital Tract Defensins and Cytokines Differ between HIV-Uninfected US and African Women

scientific article

Loss of Innate Host Defense Following Unprotected Vaginal Sex

scientific article published on 13 October 2015

Low Birth Weight in Human Immunodeficiency Virus-Exposed Uninfected Infants in Bronx, New York

scientific article published on 30 December 2017

Lower levels of interleukin-12 precede the development of tuberculosis among HIV-infected women

scientific article

Mandelic acid condensation polymer: novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entry

scientific article

Maternal Immunization with a Single-Cycle Herpes Simplex Virus (HSV) Candidate Vaccine, ΔgD-2, Protects Neonatal Mice from Lethal Viral Challenge.

scientific article published on 4 October 2017

Microbiota control immune regulation in humanized mice

scientific article published on 2 November 2017

Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity

scientific article published on 07 May 2020

Molecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infections

scientific article published on 9 May 2007

Mounting Evidence Suggests Safety and Efficacy of Immunizations Posttransplantation ⬇️

scientific article published on 01 November 2012

Mucosal Escherichia coli bactericidal activity and immune mediators are associated with HIV-1 seroconversion in women participating in the HPTN 035 trial

scientific article

Multiple receptor interactions trigger release of membrane and intracellular calcium stores critical for herpes simplex virus entry

scientific article

Murine Model of Maternal Immunization Demonstrates Protective Role for Antibodies That Mediate Antibody-Dependent Cellular Cytotoxicity in Protecting Neonates From Herpes Simplex Virus Type 1 and Type 2

scientific article published on 01 February 2020

NP-1, a rabbit alpha-defensin, prevents the entry and intercellular spread of herpes simplex virus type 2

scientific article

Neonatal Herpes Infection Associated With Direct Orogenital Suction During Ritual Jewish Circumcision.

scientific article published on 24 April 2015

Novel approaches in fighting herpes simplex virus infections

scientific article published on June 2009

Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties

scientific article published on 24 October 2013

Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa

scientific article published on 20 August 2013

PRO 2000 elicits a decline in genital tract immune mediators without compromising intrinsic antimicrobial activity

scientific article published in February 2007

PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial

scientific article published on 17 November 2005

Performance of swabs, lavage, and diluents to quantify biomarkers of female genital tract soluble mucosal mediators

scientific article

Persulfated molecular umbrellas as anti-HIV and anti-HSV agents

scientific article

Pharmacokinetic evaluation of tenofovir disoproxil fumarate released from an intravaginal ring in pigtailed macaques after 6 months of continuous use.

scientific article

Phase I randomized safety study of twice daily dosing of acidform vaginal gel: candidate antimicrobial contraceptive

scientific article

Plasma and mucosal HIV viral loads are associated with genital tract inflammation in HIV-infected women

scientific article published on August 2013

Postcoital bioavailability and antiviral activity of 0.5% PRO 2000 gel: implications for future microbicide clinical trials

scientific article (publication date: 22 January 2010)

Preclinical evaluation of sodium cellulose sulfate (Ushercell) as a contraceptive antimicrobial agent.

scientific article published on May 2002

Prioritizing prevention of HIV and sexually transmitted infections: first-generation vaginal microbicides.

scientific article

Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women.

scientific article published on 28 June 2018

Recommended Curriculum for Training in Pediatric Transplant Infectious Diseases

scientific article

Repeated administration of high-dose depot medroxyprogesterone acetate does not alter SHIVSF162p3 viral kinetics and tenofovir pharmacokinetics when delivered via intravaginal rings.

scientific article

Research gaps in defining the biological link between HIV risk and hormonal contraception

scientific article

Rigorous pre-clinical evaluation of topical microbicides to prevent transmission of human immunodeficiency virus

scientific article

Role of Interleukin 32 in Human Immunodeficiency Virus Reactivation and Its Link to Human Immunodeficiency Virus-Herpes Simplex Virus Coinfection

scientific article published on 22 December 2016

Role of mucosal immunity in preventing genital herpes infection

scientific article

SARS-CoV-2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth

scientific article published on 13 November 2020

Safety and pharmacokinetics of aciclovir in women following release from a silicone elastomer vaginal ring ⬇️

scientific article published on May 3, 2012

Seminal plasma reduces the effectiveness of topical polyanionic microbicides

scientific article

Soluble Immune Mediators and Vaginal Bacteria Impact Innate Genital Mucosal Antimicrobial Activity in Young Women

scientific article

Stage of change behavioral assessment tool fails to predict the prevalence of chlamydia in an urban adolescent health clinic

scientific article published on August 2006

Strategies for the prevention of cytomegalovirus infection and disease in pediatric liver transplantation recipients

scientific article

Sulfated carbohydrate compounds prevent microbial adherence by sexually transmitted disease pathogens ⬇️

scientific article published on December 1, 1997

Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety

scientific article

Tenofovir disoproxil fumarate intravaginal ring for HIV pre-exposure prophylaxis in sexually active women: a phase 1, single-blind, randomised, controlled trial

scientific article published on 15 July 2019

Tenofovir disoproxil fumarate intravaginal ring protects high-dose depot medroxyprogesterone acetate-treated macaques from multiple SHIV exposures.

scientific article

The Effect of Hormonal Contraception on Cervicovaginal Mucosal End Points Associated with HIV Acquisition

scientific article published on 14 May 2019

The Vaginal Acquisition and Dissemination of HIV-1 Infection in a Novel Transgenic Mouse Model Is Facilitated by Coinfection with Herpes Simplex Virus 2 and Is Inhibited by Microbicide Treatment.

scientific article

The changing face of post-transplant lymphoproliferative disease in the era of molecular EBV monitoring

scientific article published on 07 January 2010

The cotton rat provides a novel model to study genital herpes infection and to evaluate preventive strategies

scientific article

Therapeutic blockade of sexually transmitted pathogens ⬇️

scientific article published on October 1, 1997

Theta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry

scientific article published on May 2004

Topical microbicides for the prevention of genital herpes infection

scientific article

Topical prophylaxis for HIV prevention in women: becoming a reality

scientific article

US6 Gene Deletion in Herpes Simplex Virus Type 2 Enhances Dendritic Cell Function and T Cell Activation.

scientific article published on 10 November 2017

Understanding basic mechanisms and optimizing assays to evaluate the efficacy of vaginal microbicides

scientific article published on March 2009

Use of mandelic acid condensation polymer (SAMMA), a new antimicrobial contraceptive agent, for vaginal prophylaxis

scientific article

Use of the dye stain assay and ultraviolet light test for assessing vaginal insertion of placebo-filled applicators before and after sex

scientific article

Vaccination Route as a Determinant of Protective Antibody Responses against Herpes Simplex Virus

scientific article published on 05 June 2020

Vaginal microbiome modulates topical antiretroviral drug pharmacokinetics

Vaginally delivered tenofovir disoproxil fumarate provides greater protection than tenofovir against genital herpes in a murine model of efficacy and safety.

scientific article published on 09 December 2013

Very low incidence of <i>Clostridioides difficile</i> infection in pediatric sickle cell disease patients

scientific article published on 14 September 2020

Viral and cellular requirements for entry of herpes simplex virus type 1 into primary neuronal cells ⬇️

scientific article published on March 1, 1998

Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING.

scientific article published on 17 June 2012

Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women

scientific article

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