List of works - Gabriela Trevisan

A novel, potent, oral active and safe antinociceptive pyrazole targeting kappa opioid receptors.

scientific article

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

scientific article published on 18 August 2010

Analgesic and side effects of intravenous recombinant Phα1β

scientific article published on 17 April 2020

Analgesic effect in rodents of native and recombinant Ph alpha 1beta toxin, a high-voltage-activated calcium channel blocker isolated from armed spider venom

scientific article

Anti-genotoxic and anti-mutagenic effects of melatonin supplementation in a mouse model of melanoma

scientific article published on 17 February 2020

Anti-inflammatory and antioxidant effects of Aloe saponaria Haw in a model of UVB-induced paw sunburn in rats

scientific article published on 12 March 2014

Anti-nociceptive effect of stigmasterol in mouse models of acute and chronic pain.

scientific article

Antiinflammatory effects of Viola tricolor gel in a model of sunburn in rats and the gel stability study.

scientific article published on 3 September 2013

Antinociceptive activity and mechanism of action of hydroalcoholic extract and dichloromethane fraction of Amphilophium crucigerum seeds in mice

scientific article published on 15 November 2016

Antinociceptive activity of Copaifera officinalis Jacq. L oil and kaurenoic acid in mice

scientific article published on 16 May 2019

Antinociceptive activity of Mirabilis jalapa in mice

scientific article published on 8 August 2008

Antinociceptive and anti-inflammatory effects of Aloe saponaria Haw on thermal injury in rats.

scientific article published on 17 January 2013

Antinociceptive effect of Mirabilis jalapa on acute and chronic pain models in mice

scientific article published on 29 July 2013

Antiplatelet, Antithrombotic, and Fibrinolytic Activities of Campomanesia xanthocarpa

scientific article

Biomarkers of Subclinical Atherosclerosis and Natural Products as Complementary Alternative Medicine

scientific article

Buddleja thyrsoides Lam. crude extract presents antinociceptive effect on an arthritic pain model in mice

scientific article published on 23 July 2017

Characterisation of nociception and inflammation observed in a traumatic muscle injury model in rats

scientific article published on 14 July 2020

Characterization of Cancer-Induced Nociception in a Murine Model of Breast Carcinoma

scientific article published on 08 March 2019

Copaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice

scientific article published on 12 December 2019

Dacarbazine alone or associated with melanoma-bearing cancer pain model induces painful hypersensitivity by TRPA1 activation in mice

scientific article published on 08 October 2019

Diosmetin as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive activity in mice

scientific article published on 14 November 2018

Effects of Campomanesia xanthocarpa on inflammatory processes, oxidative stress, endothelial dysfunction and lipid biomarkers in hypercholesterolemic individuals

scientific article published on 25 February 2014

Eriodictyol: a flavonoid antagonist of the TRPV1 receptor with antioxidant activity

scientific article published on 16 November 2010

Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice

scientific article published on 11 April 2014

Hydroalcoholic extract of leaf of Arachis hypogaea L. (Fabaceae) did not induce toxic effects in the repeated-dose toxicity study in rats

scientific article published on 13 May 2020

Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties

scientific article published on 26 July 2012

Inhibitory effect of Scutia buxifolia extracts, fractions, and ursolic acid on Na(+), K(+)-ATPase activity in vitro in membranes purified from rat hearts.

scientific article published on 21 December 2015

Involvement of TRPV1 and the efficacy of α-spinasterol on experimental fibromyalgia symptoms in mice

scientific article published on 08 January 2020

Involvement of mast cells in a mouse model of postoperative pain

scientific article

Macrophages and Schwann cell TRPA1 mediate chronic allodynia in a mouse model of complex regional pain syndrome type I

scientific article published on 18 April 2020

Management of Neuropathic Chronic Pain with Methadone Combined with Ketamine: A Randomized, Double Blind, Active-Controlled Clinical Trial

scientific article published in March 2017

Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum.

scientific article published in August 2013

Mechanisms involved in the nociception triggered by the venom of the armed spider Phoneutria nigriventer

scientific article

Nasturtium officinale R. Br. effectively reduces the skin inflammation induced by croton oil via glucocorticoid receptor-dependent and NF-κB pathways without causing toxicological effects in mice

scientific article published on 17 October 2018

Neuronal and non-neuronal transient receptor potential ankyrin 1 mediates UVB radiation-induced skin inflammation in mice

scientific article published on 07 October 2020

Nociception in a Progressive Multiple Sclerosis Model in Mice Is Dependent on Spinal TRPA1 Channel Activation

scientific article published on 24 February 2020

Nociceptive mechanisms involved in the acute and chronic phases of a complex regional pain syndrome type 1 model in mice

scientific article published on 18 July 2019

Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.

scientific article published on 8 August 2013

Participation of the TRPV1 receptor in the development of acute gout attacks

scientific article published on 31 October 2013

Participation of transient receptor potential vanilloid 1 in paclitaxel-induced acute visceral and peripheral nociception in rodents.

scientific article published on 22 March 2018

Peanut leaf extract has antioxidant and anti-inflammatory activity but no acute toxic effects

scientific article published on 18 June 2019

PhKv a toxin isolated from the spider venom induces antinociception by inhibition of cholinesterase activating cholinergic system

scientific article published on 26 October 2017

Phα1β, a peptide from the venom of the spider Phoneutria nigriventer shows antinociceptive effects after continuous infusion in a neuropathic pain model in rats

scientific article published on 01 July 2014

Potentiation of Paclitaxel-Induced Pain Syndrome in Mice by Angiotensin I Converting Enzyme Inhibition and Involvement of Kinins.

scientific article published on 14 November 2016

Prevalence of depression and anxiety in the different clinical forms of multiple sclerosis and associations with disability: A systematic review and meta-analysis

scientific article published in 2022

Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats

scientific article published on 07 May 2011

Role of transient receptor potential ankyrin 1 (TRPA1) on nociception caused by a murine model of breast carcinoma

scientific article published on 29 November 2019

Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

scientific article published in December 2017

Spider peptide Phα1β induces analgesic effect in a model of cancer pain.

scientific article published on 25 June 2013

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.

scientific article

Structural improvement of compounds with analgesic activity: AC-MPF4, a compound with mixed anti-inflammatory and antinociceptive activity via opioid receptor

scientific article published on 13 December 2014

Study of oxidative and inflammatory parameters in LDLr-KO mice treated with a hypercholesterolemic diet: Comparison between the use of Campomanesia xanthocarpa and acetylsalicylic acid

scientific article published on 12 December 2015

TRPA1 activation mediates nociception behaviors in a mouse model of relapsing-remitting experimental autoimmune encephalomyelitis

scientific article published on 08 February 2020

TRPA1 involvement in analgesia induced by Tabernaemontana catharinensis ethyl acetate fraction in mice

scientific article published on 18 September 2018

TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress

scientific article published on 16 March 2016

TRPA1 receptor stimulation by hydrogen peroxide is critical to trigger hyperalgesia and inflammation in a model of acute gout

scientific article published on 26 April 2014

Tabernaemontana catharinensis leaves effectively reduce the irritant contact dermatitis by glucocorticoid receptor-dependent pathway in mice

scientific article published on 04 November 2018

Tabernaemontana catharinensis leaves exhibit topical anti-inflammatory activity without causing toxicity

scientific article published on 13 November 2018

The TRPA1 channel in migraine mechanism and treatment

scientific article

The antinociceptive and anti-inflammatory effects of the crude extract of Jatropha isabellei in a rat gout model

scientific article published on 2 November 2012

The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain

scientific article published on 10 December 2014

The potential antidepressant-like effect of imidazoline I2 ligand 2-BFI in mice

scientific article published on 21 November 2011

The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents

scientific article

The spider toxin Phα1β recombinant possesses strong analgesic activity

scientific article published on 17 May 2017

Topical transient receptor potential ankyrin 1 antagonist treatment attenuates nociception and inflammation in an ultraviolet B radiation-induced burn model in mice

scientific article published on 18 January 2020

Topical treatment with a transient receptor potential ankyrin 1 (TRPA1) antagonist reduced nociception and inflammation in a thermal lesion model in rats

scientific article published on 17 September 2018

Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain

article

Transient receptor potential ankyrin 1 receptor stimulation by hydrogen peroxide is critical to trigger pain during monosodium urate-induced inflammation in rodents

scientific article

TsNTxP, a non-toxic protein from Tityus serrulatus scorpion venom, induces antinociceptive effects by suppressing glutamate release in mice

scientific article published on 03 May 2019

α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.

scientific article

List of works by Gabriela Trevisan

A novel, potent, oral active and safe antinociceptive pyrazole targeting kappa opioid receptors.

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

Analgesic and side effects of intravenous recombinant Phα1β

Analgesic effect in rodents of native and recombinant Ph alpha 1beta toxin, a high-voltage-activated calcium channel blocker isolated from armed spider venom

Anti-genotoxic and anti-mutagenic effects of melatonin supplementation in a mouse model of melanoma

Anti-inflammatory and antioxidant effects of Aloe saponaria Haw in a model of UVB-induced paw sunburn in rats

Anti-nociceptive effect of stigmasterol in mouse models of acute and chronic pain.

Antiinflammatory effects of Viola tricolor gel in a model of sunburn in rats and the gel stability study.

Antinociceptive activity and mechanism of action of hydroalcoholic extract and dichloromethane fraction of Amphilophium crucigerum seeds in mice

Antinociceptive activity of Copaifera officinalis Jacq. L oil and kaurenoic acid in mice

Antinociceptive activity of Mirabilis jalapa in mice

Antinociceptive and anti-inflammatory effects of Aloe saponaria Haw on thermal injury in rats.

Antinociceptive effect of Mirabilis jalapa on acute and chronic pain models in mice

Antiplatelet, Antithrombotic, and Fibrinolytic Activities of Campomanesia xanthocarpa

Biomarkers of Subclinical Atherosclerosis and Natural Products as Complementary Alternative Medicine

Buddleja thyrsoides Lam. crude extract presents antinociceptive effect on an arthritic pain model in mice

Characterisation of nociception and inflammation observed in a traumatic muscle injury model in rats

Characterization of Cancer-Induced Nociception in a Murine Model of Breast Carcinoma

Copaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice

Dacarbazine alone or associated with melanoma-bearing cancer pain model induces painful hypersensitivity by TRPA1 activation in mice

Diosmetin as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive activity in mice

Effects of Campomanesia xanthocarpa on inflammatory processes, oxidative stress, endothelial dysfunction and lipid biomarkers in hypercholesterolemic individuals

Eriodictyol: a flavonoid antagonist of the TRPV1 receptor with antioxidant activity

Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice

Hydroalcoholic extract of leaf of Arachis hypogaea L. (Fabaceae) did not induce toxic effects in the repeated-dose toxicity study in rats

Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties

Inhibitory effect of Scutia buxifolia extracts, fractions, and ursolic acid on Na(+), K(+)-ATPase activity in vitro in membranes purified from rat hearts.

Involvement of TRPV1 and the efficacy of α-spinasterol on experimental fibromyalgia symptoms in mice

Involvement of mast cells in a mouse model of postoperative pain

Macrophages and Schwann cell TRPA1 mediate chronic allodynia in a mouse model of complex regional pain syndrome type I

Management of Neuropathic Chronic Pain with Methadone Combined with Ketamine: A Randomized, Double Blind, Active-Controlled Clinical Trial

Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum.

Mechanisms involved in the nociception triggered by the venom of the armed spider Phoneutria nigriventer

Nasturtium officinale R. Br. effectively reduces the skin inflammation induced by croton oil via glucocorticoid receptor-dependent and NF-κB pathways without causing toxicological effects in mice

Neuronal and non-neuronal transient receptor potential ankyrin 1 mediates UVB radiation-induced skin inflammation in mice

Nociception in a Progressive Multiple Sclerosis Model in Mice Is Dependent on Spinal TRPA1 Channel Activation

Nociceptive mechanisms involved in the acute and chronic phases of a complex regional pain syndrome type 1 model in mice

Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.

Participation of the TRPV1 receptor in the development of acute gout attacks

Participation of transient receptor potential vanilloid 1 in paclitaxel-induced acute visceral and peripheral nociception in rodents.

Peanut leaf extract has antioxidant and anti-inflammatory activity but no acute toxic effects

PhKv a toxin isolated from the spider venom induces antinociception by inhibition of cholinesterase activating cholinergic system

Phα1β, a peptide from the venom of the spider Phoneutria nigriventer shows antinociceptive effects after continuous infusion in a neuropathic pain model in rats

Potentiation of Paclitaxel-Induced Pain Syndrome in Mice by Angiotensin I Converting Enzyme Inhibition and Involvement of Kinins.

Prevalence of depression and anxiety in the different clinical forms of multiple sclerosis and associations with disability: A systematic review and meta-analysis

Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats

Role of transient receptor potential ankyrin 1 (TRPA1) on nociception caused by a murine model of breast carcinoma

Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

Spider peptide Phα1β induces analgesic effect in a model of cancer pain.

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.

Structural improvement of compounds with analgesic activity: AC-MPF4, a compound with mixed anti-inflammatory and antinociceptive activity via opioid receptor

Study of oxidative and inflammatory parameters in LDLr-KO mice treated with a hypercholesterolemic diet: Comparison between the use of Campomanesia xanthocarpa and acetylsalicylic acid

TRPA1 activation mediates nociception behaviors in a mouse model of relapsing-remitting experimental autoimmune encephalomyelitis

TRPA1 involvement in analgesia induced by Tabernaemontana catharinensis ethyl acetate fraction in mice

TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress

TRPA1 receptor stimulation by hydrogen peroxide is critical to trigger hyperalgesia and inflammation in a model of acute gout

Tabernaemontana catharinensis leaves effectively reduce the irritant contact dermatitis by glucocorticoid receptor-dependent pathway in mice

Tabernaemontana catharinensis leaves exhibit topical anti-inflammatory activity without causing toxicity

The TRPA1 channel in migraine mechanism and treatment

The antinociceptive and anti-inflammatory effects of the crude extract of Jatropha isabellei in a rat gout model

The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain

The potential antidepressant-like effect of imidazoline I2 ligand 2-BFI in mice

The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents

The spider toxin Phα1β recombinant possesses strong analgesic activity

Topical transient receptor potential ankyrin 1 antagonist treatment attenuates nociception and inflammation in an ultraviolet B radiation-induced burn model in mice

Topical treatment with a transient receptor potential ankyrin 1 (TRPA1) antagonist reduced nociception and inflammation in a thermal lesion model in rats

Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain

Transient receptor potential ankyrin 1 receptor stimulation by hydrogen peroxide is critical to trigger pain during monosodium urate-induced inflammation in rodents

TsNTxP, a non-toxic protein from Tityus serrulatus scorpion venom, induces antinociceptive effects by suppressing glutamate release in mice

α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.