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List of works by Roger S Buxton

A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor

scientific journal article

A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor

article

A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice

scientific journal article

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice

scientific article

An attenuated mutant of the Rv1747 ATP-binding cassette transporter of Mycobacterium tuberculosis and a mutant of its cognate kinase, PknF, show increased expression of the efflux pump-related iniBAC operon

scientific article published on 23 August 2013

An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis

scientific article

Characterisation of complex formation between members of the Mycobacterium tuberculosis complex CFP-10/ESAT-6 protein family: towards an understanding of the rules governing complex formation and thereby functional flexibility

scientific journal article

Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence

scientific article

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

scientific article

Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches

scientific article published on 07 February 2014

Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents

scientific article

Erratum to “Genome analysis shows a common evolutionary origin for the dominant strains of Mycobacterium tuberculosis in a UK South Asian community” [Tuberculosis 87 (2007) 426–436]

article

EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.

scientific article published on 9 December 2011

Forkhead-associated (FHA) domain containing ABC transporter Rv1747 is positively regulated by Ser/Thr phosphorylation in Mycobacterium tuberculosis

scientific article

Genome analysis shows a common evolutionary origin for the dominant strains of Mycobacterium tuberculosis in a UK South Asian community

scientific article

Genome structure in the vole bacillus, Mycobacterium microti, a member of the Mycobacterium tuberculosis complex with a low virulence for humans

scientific article

Genomic mapping of cAMP receptor protein (CRP Mt) in Mycobacterium tuberculosis: relation to transcriptional start sites and the role of CRPMt as a transcription factor

scientific article

Global analysis of the regulon of the transcriptional repressor LexA, a key component of SOS response in Mycobacterium tuberculosis.

scientific article

Induced ectopic expression of HigB toxin in Mycobacterium tuberculosis results in growth inhibition, reduced abundance of a subset of mRNAs and cleavage of tmRNA

scientific journal article

Long range transcriptional control of virulence critical genes inMycobacterium tuberculosisby nucleoid-associated proteins? ⬇️

scientific article published on June 22, 2012

Long-range transcriptional control of an operon necessary for virulence-critical ESX-1 secretion in Mycobacterium tuberculosis

scientific article

Mechanistic insight into the nitrosylation of the [4Fe-4S] cluster of WhiB-like proteins

scientific article

Mycobacterium tuberculosis WhiB1 is an essential DNA-binding protein with a nitric oxide-sensitive iron-sulfur cluster

scientific journal article

Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2 ⬇️

scientific article published on March 29, 2012

Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties

scientific journal article

New anti-tuberculosis agents amongst known drugs

scientific article

Novel regulatory roles of cAMP receptor proteins in fast-growing environmental mycobacteria

scientific article published on 18 December 2014

Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response

scientific article published on 06 July 2013

Single nucleotide polymorphisms that cause structural changes in the cyclic AMP receptor protein transcriptional regulator of the tuberculosis vaccine strain Mycobacterium bovis BCG alter global gene expression without attenuating growth

scientific article published on 10 March 2008

Structural and functional analysis of phosphothreonine-dependent FHA domain interactions

scientific article

Structure of a Wbl protein and implications for NO sensing by M. tuberculosis.

scientific article published on 22 December 2017

Structure-Function Relationships of the Mycobacterium tuberculosis Transcription Factor WhiB1 ⬇️

scientific article published on July 5, 2012

Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis

scientific article

The majority of inducible DNA repair genes in Mycobacterium tuberculosis are induced independently of RecA

scientific article published on 01 November 2003

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