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List of works by Chad M Thompson

A chronic oral reference dose for hexavalent chromium-induced intestinal cancer

scientific article

A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes.

scientific article published on 17 September 2013

A response to "A quantitative assessment of the carcinogenicity of hexavalent chromium by the oral route and its relevance to human exposure"

scientific article published on 12 February 2011

A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates

scientific article published on 21 April 2018

A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats

scientific article published on 13 May 2015

An Adverse Outcome Pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events

scientific article published on 21 April 2018

An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet

scientific article published on 04 November 2020

Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium

scientific article (publication date: 2011)

Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis

scientific article

Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water.

scientific article published on 9 April 2013

Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: an in silico comparison with mutagenic and nonmutagenic carcinogens across tissues

scientific article published on 15 June 2012

Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks

scientific article published on 06 March 2020

Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures

scientific article published on 28 August 2014

Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans

scientific article published on 05 May 2018

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans

scientific article

Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats

scientific article

Assessment of the mutagenic potential of hexavalent chromium in the duodenum of big blue® rats

scientific article published on 4 July 2017

Benchmark Dose Modeling Estimates of the Concentrations of Inorganic Arsenic That Induce Changes to the Neonatal Transcriptome, Proteome, and Epigenome in a Pregnancy Cohort.

scientific article

Comparative toxicogenomic analysis of oral Cr(VI) exposure effects in rat and mouse small intestinal epithelia

scientific article published on 28 April 2012

Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway

scientific article published on 26 September 2019

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium

scientific article published in January 2017

Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium.

scientific article published on 6 March 2016

Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: implications for carcinogenic modes of action.

scientific article published on 19 October 2011

Comparison of threshold of toxicological concern (TTC) values to oral reference dose (RfD) values

scientific article published on 27 March 2020

Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium

scientific article published on 01 February 2022

Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling ⬇️

scientific article published on August 31, 2012

Development of an oral reference dose for the perfluorinated compound GenX

scientific article published on 18 June 2019

Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations

scientific article

Development of toxicity values and exposure estimates for tetrabromobisphenol A: application in a margin of exposure assessment.

scientific article published on 30 March 2015

Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy.

scientific article published on 14 May 2015

Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice

scientific article published on 08 July 2020

Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water

scientific article published on December 2011

Hexavalent chromium reduction kinetics in rodent stomach contents

scientific article published on 08 June 2012

High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice

scientific article published on 10 January 2014

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure

scientific article

Identifying Attributes That Influence In Vitro-to-In Vivo Concordance by Comparing In Vitro Tox21 Bioactivity Versus In Vivo DrugMatrix Transcriptomic Responses Across 130 Chemicals.

scientific article published in January 2019

Inhalation cancer risk assessment of cobalt metal

scientific article published on 10 May 2016

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium.

scientific article published on 24 October 2017

Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium.

scientific article

Letter to the Editor Regarding Banu et al. (2018). Chromium Accumulation on Human Placental Oxidative Stress and Apoptosis

scientific article published on 01 October 2018

Reevaluation and Classification of Duodenal Lesions in B6C3F1 Mice and F344 Rats from 4 Studies of Hexavalent Chromium in Drinking Water

scientific article published on 4 November 2015

Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis

scientific article published on 25 January 2019

Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water

scientific article

Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents

scientific article

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.

scientific article

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