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List of works by Tom Coleman

Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases

scientific article published on 24 February 2020

CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives

scientific article published in 2015

Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation

scientific article published on 17 May 2018

Different Geometric Requirements for Cytochrome P450-Catalyzed Aliphatic Versus Aromatic Hydroxylation Results in Chemoselective Oxidation

scientific article published on 6 January 2022

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

scientific article published in December 2022

Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation

scientific article published on 14 December 2022

Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions

scientific article published on 27 December 2022

Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions

scientific article published on 13 November 2019

Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes

scientific article published on 04 April 2020

The Biochemical Impact of Extracting an Embedded Adenylate Kinase Domain Using Circular Permutation

scientific article published on 15 February 2024

The Oxidation of Oxygen and Sulfur‐Containing Heterocycles by Cytochrome P450 Enzymes

scientific article published on 2 August 2023

The importance of the benzoic acid carboxylate moiety for substrate recognition by CYP199A4 from Rhodopseudomonas palustris HaA2.

scientific article

To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme

scientific article published on 15 December 2021