List of works by Philippe Alexandre Cassier

A Phase 1 dose-escalation study to evaluate safety, pharmacokinetics and pharmacodynamics of AsiDNA, a first-in-class DNA repair inhibitor, administered intravenously in patients with advanced solid tumours

scientific article published on 25 August 2020

A Retrospective Multicentric Study of Ewing Sarcoma Family of Tumors in Patients Older Than 50: Management and Outcome.

scientific article published on 20 December 2017

A phase 2 trial of whole-brain radiotherapy combined with intravenous chemotherapy in patients with brain metastases from breast cancer

scientific article

A phase I study of single-agent nilotinib or in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors

scientific article

Abstract 2267: Long term prognostic impact of CD4 and CD8 lymphopenia and rapid recovery in a cohort of 220 patients with a 10 years follow-up

Abstract 5578: IGF-1R nuclear staining in tumor cells identifies sarcoma patients with a prolonged progression free survival after IGF-1R monoclonal antibody therapy

Antiangiogenic effects in patients with progressive desmoplastic small round cell tumor: data from the French national registry dedicated to the use of off-labeled targeted therapy in sarcoma (OUTC's)

scientific article

Autophagy as a therapeutic target in pancreatic cancer

scientific article published on 15 September 2020

CD4 lymphopenia to identify end-of-life metastatic cancer patients

scientific article published on 13 December 2012

Complete response of hepatocellular carcinoma with systemic combination chemotherapy: not to get out the chemotherapy?

scientific article published in August 2010

Efficacy of trabectedin for advanced sarcomas in clinical trials versus compassionate use programs: analysis of 92 patients treated in a single institution

scientific article published in January 2010

Emerging drugs for the treatment of soft tissue sarcomas

scientific article published on March 2007

Gastrointestinal stromal tumors (GIST): a rare entity, a tumor model for personalized therapy, and yet ten different molecular subtypes

scientific article published on May 2012

Generation of a conditional Flpo/FRT mouse model expressing constitutively active TGFβ in fibroblasts

scientific article published on 03 March 2020

Imatinib and solid tumours

scientific article published in January 2008

Imatinib mesilate for the treatment of gastrointestinal stromal tumour

scientific article published on May 2008

Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas

scientific article

Is there a role for discontinuing imatinib in patients with advanced gastrointestinal stromal tumour?

scientific article published on July 2009

KIT exon 10 variant (c.1621 A > C) single nucleotide polymorphism as predictor of GIST patient outcome

scientific article published on 24 October 2015

Long term term follow-up of tyrosine kinase inhibitors treatments in inoperable or relapsing diffuse type tenosynovial giant cell tumors (dTGCT)

scientific article published on 20 May 2020

Long-term efficacy of imatinib mesylate in patients with advanced Tenosynovial Giant Cell Tumor

scientific article published on 10 October 2019

Long-term outcome and effect of maintenance therapy in patients with advanced sarcoma treated with trabectedin: an analysis of 181 patients of the French ATU compassionate use program

scientific article

Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas

scientific article published on 23 June 2009

Neoadjuvant imatinib in patients with locally advanced non metastatic GIST in the prospective BFR14 trial

scientific article

Nilotinib in locally advanced pigmented villonodular synovitis: a multicentre, open-label, single-arm, phase 2 trial.

scientific article published on 20 March 2018

Novel approaches to gastrointestinal stromal tumors resistant to imatinib and sunitinib

scientific article published on December 2008

Outcome of patients receiving chemotherapy for advanced biliary tract or gallbladder carcinoma

scientific article published in September 2010

Outcome of patients with advanced solitary fibrous tumors: the Centre Léon Bérard experience

scientific article

Paclitaxel Given Once Per Week With or Without Bevacizumab in Patients With Advanced Angiosarcoma: A Randomized Phase II Trial

scientific article published on 27 July 2015

Pazopanib plus best supportive care versus best supportive care alone in advanced gastrointestinal stromal tumours resistant to imatinib and sunitinib (PAZOGIST): a randomised, multicentre, open-label phase 2 trial

scientific article published on 5 April 2016

Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer

scientific article

Recombinant erythropoietin for the anaemia of patients with advanced Gastrointestinal Stromal Tumours (GIST) receiving imatinib: an active agent only in non progressive patients

scientific article

Serum creatine kinase increase in patients treated with tyrosine kinase inhibitors for solid tumors.

scientific article

Soft tissue sarcomas: are all soft tissue sarcomas treated with the same drugs?

scientific article published on September 2011

Survival impact of centralization and clinical guidelines for soft tissue sarcoma (A prospective and exhaustive population-based cohort)

scientific article

Targeted therapy of sarcomas

scientific article

The off-label use of targeted therapies in sarcomas: the OUTC'S program

scientific article

The sum of gains and losses of genes encoding the protein tyrosine kinase targets predicts response to multi-kinase inhibitor treatment: Characterization, validation, and prognostic value

scientific article

Therapeutic pipeline for soft-tissue sarcoma

scientific article published on 13 September 2011

[Molecular biology of sarcoma and therapeutic choices].

scientific article published on 13 January 2015

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