List of works - Jaime Imitola

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

scientific article published in December 2017

Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease

scientific article

Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis

scientific article

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation

scientific article published in Nature Communications

Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration

scientific article

Corticotropin-releasing hormone contributes to the peripheral inflammatory response in experimental autoimmune encephalomyelitis

scientific article

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

scientific article

Cytokines in multiple sclerosis: from bench to bedside

scientific article

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

scientific article

Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis

scientific article published on 01 March 2006

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

scientific article

Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis

scientific article published on 26 June 2008

Elevated expression of granulocyte-macrophage colony-stimulating factor receptor in multiple sclerosis lesions

scientific article published on 22 December 2017

Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration

scientific article published on May 2007

Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex

scientific article published in November 2004

Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy

scientific article published on 27 April 2015

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

scientific article

Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis

scientific article

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

scholarly article

Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies

scientific article

Interferon-beta treatment alters peripheral blood monocytes chemokine production in MS patients

scientific article published on 01 May 2002

Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

scientific article

Microglia-mediated nitric oxide cytotoxicity of T cells following amyloid beta-peptide presentation to Th1 cells

scientific article published on 01 September 2003

Mild COVID-19 infection despite chronic B cell depletion in a patient with aquaporin-4-positive neuromyelitis Optica spectrum disorder.

scientific article published on 19 May 2020

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice

scientific article

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

scientific article (publication date: 2004)

Neural stem cell biology may be well suited for improving brain tumor therapies.

scientific article

Neural stem cells and the future treatment of neurological diseases: raising the standard

scientific article

Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets.

scientific article published in July 2006

Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli

scientific article

Neurology Grand Rounds Complications from "Stem Cell Tourism" in Neurology

scientific article published on 07 July 2020

Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis

scientific article

Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis

scientific article published on 22 September 2007

Persistent inflammation alters the function of the endogenous brain stem cell compartment

scientific article published on 30 August 2008

Reversible neural stem cell niche dysfunction in a model of multiple sclerosis.

scientific article

Safety and Efficacy of Rituximab: Experience of a Single Multiple Sclerosis Center

scientific article published on 31 January 2018

Stem cells: cross-talk and developmental programs

scientific article

Subventricular zone microglia transcriptional networks

scientific article

Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance.

scientific article

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

scientific article

The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice

scientific journal article

Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.

scientific article published in July 2005

iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases

scientific article published on 19 October 2017

List of works by Jaime Imitola

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease

Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation

Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration

Corticotropin-releasing hormone contributes to the peripheral inflammatory response in experimental autoimmune encephalomyelitis

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

Cytokines in multiple sclerosis: from bench to bedside

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis

Elevated expression of granulocyte-macrophage colony-stimulating factor receptor in multiple sclerosis lesions

Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration

Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex

Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies

Interferon-beta treatment alters peripheral blood monocytes chemokine production in MS patients

Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

Microglia-mediated nitric oxide cytotoxicity of T cells following amyloid beta-peptide presentation to Th1 cells

Mild COVID-19 infection despite chronic B cell depletion in a patient with aquaporin-4-positive neuromyelitis Optica spectrum disorder.

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

Neural stem cell biology may be well suited for improving brain tumor therapies.

Neural stem cells and the future treatment of neurological diseases: raising the standard

Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets.

Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli

Neurology Grand Rounds Complications from "Stem Cell Tourism" in Neurology

Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis

Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis

Persistent inflammation alters the function of the endogenous brain stem cell compartment

Reversible neural stem cell niche dysfunction in a model of multiple sclerosis.

Safety and Efficacy of Rituximab: Experience of a Single Multiple Sclerosis Center

Stem cells: cross-talk and developmental programs

Subventricular zone microglia transcriptional networks

Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance.

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice

Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.

iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases