List of works by Johan Grunewald

A Gene-Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis

scientific article published on 09 December 2019

A method for generating pulmonary neutrophilia using aerosolized lipopolysaccharide

scientific article published on 15 December 2014

A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination

scientific article published on January 2006

A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1

scientific article

A quantitative proteomic analysis of soluble bronchoalveolar fluid proteins from patients with sarcoidosis and chronic beryllium disease

scientific article published on 01 March 2007

Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation

scientific article

Alterations in the membrane-associated proteome fraction of alveolar macrophages in sarcoidosis.

scientific article published on 29 March 2016

Altered Fc galactosylation in IgG4 is a potential serum marker for chronic lung disease

scientific article published on 31 July 2018

Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis

scientific article published on 29 May 2009

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

scientific article

Antigen-specific multifunctional T-cells in sarcoidosis patients with Lofgren's syndrome

scientific article published on 19 December 2011

Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples

scientific article published on 24 July 2016

Are infectious diseases risk factors for sarcoidosis or a result of reverse causation? Findings from a population-based nested case-control study

scientific article published on 11 February 2020

Assessing recent smoking status by measuring exhaled carbon monoxide levels

scientific article

Association between number and type of different ACPA fine specificities with lung abnormalities in early, untreated rheumatoid arthritis

scientific article published on 01 September 2020

Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure

scientific article

Autoimmune T cell responses to antigenic peptides presented by bronchoalveolar lavage cell HLA-DR molecules in sarcoidosis

scientific article published on 27 September 2009

Bronchoalveolar lavage results are independent of season, age, gender and collection site

scientific article

CD4+ T cells in sarcoidosis: targets and tools

scientific article published on 01 November 2006

CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope

scientific article published on 4 October 2021

Cell recovery in bronchoalveolar lavage fluid in smokers is dependent on cumulative smoking history

scientific article (publication date: 2012)

Coeliac disease and risk of sarcoidosis

scientific article published in September 2007

Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis.

scientific article published on 17 July 2017

Correspondence for "Clinical epidemiology of familial sarcoidosis: A systematic literature review"

scientific article published on 13 May 2019

Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients

scientific article

Differential regulation of neurotrophin expression in human bronchial smooth muscle cells

scientific article

Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function

scientific article

Distribution of T-cell subsets in BAL fluid of patients with mild to moderate COPD depends on current smoking status and not airway obstruction

scientific article published on 01 April 2014

Effects of examination stress on psychological responses, sleep and allergic symptoms in atopic and non-atopic students

scientific article published in January 2009

Effects of neurotrophins on human bronchial smooth muscle cell migration and matrix metalloproteinase-9 secretion.

scientific article published on 29 May 2007

Elevated exhaled nitric oxide in allergen-provoked asthma is associated with airway epithelial iNOS.

scientific article

Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients

scientific article published on 4 June 2016

Enhanced CD8(+) cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease

scientific article published on 13 October 2017

Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype

scientific article published on 26 May 2016

Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis

scientific article

Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals.

scientific article published on 20 April 2018

Familial aggregation and heritability of sarcoidosis: a Swedish nested case−control study

scholarly article by Marios Rossides et al published 25 June 2018 in European Respiratory Journal

Gender differences in the T-cell profiles of the airways in COPD patients associated with clinical phenotypes

scientific article published on 20 December 2016

Gene expression analysis of membrane transporters and drug-metabolizing enzymes in the lung of healthy and COPD subjects

scientific article published on 12 June 2014

Genetics of sarcoidosis

scientific article published on 01 June 2014

Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis

scientific journal article

HLA-DQ associations and T-cell receptor V-gene usage in peripheral blood of Swedish myasthenia gravis patients ⬇️

scientific article published on 01 June 1997

Health effects of a subway environment in mild asthmatic volunteers

scientific article published on 12 October 2011

High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.

scientific article published on 10 December 2015

High-intensity resistance training in newly diagnosed sarcoidosis- an exploratory study of effects on lung function, muscle strength, fatigue, dyspnea, health-related quality of life and lung immune cells

scientific article published on 21 February 2020

Higher monocyte expression of TLR2 and TLR4, and enhanced pro-inflammatory synergy of TLR2 with NOD2 stimulation in sarcoidosis

scientific article published on 05 September 2008

Human leukocyte antigen class I alleles and the disease course in sarcoidosis patients

scientific article (publication date: 15 March 2004)

Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren's syndrome using high-content peptide microarrays

scientific article published on 31 January 2017

Hypoxia but not cigarette smoke modulates VEGF secretion from human T cells

scientific article published on 01 December 2009

Identification of HLA-DR-bound peptides presented by human bronchoalveolar lavage cells in sarcoidosis

scientific article

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk

scientific article

Immune cell activation and cytokine release after stimulation of whole blood with pneumococcal C-polysaccharide and capsular polysaccharides

scientific article published on 16 July 2016

Immunogenetics of Disease-Causing Inflammation in Sarcoidosis

scientific article published on August 2015

In Situ Humoral Immunity to Vimentin in HLA-DRB1*03+ Patients With Pulmonary Sarcoidosis

scientific article published on 09 July 2018

In the eye of the beholder: does the master see the SameSpots as the novice?

scientific article published in March 2010

Increased pulmonary Wnt (wingless/integrated)-signaling in patients with sarcoidosis.

scientific article

Infection risk in sarcoidosis patients treated with methotrexate compared to azathioprine: A retrospective 'target trial' emulated with Swedish real-world data

scientific article published on 04 January 2021

Limited airway effects in mild asthmatics after exposure to air pollution in a road tunnel

scientific article published on 10 July 2010

Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD.

scientific article published on 8 March 2018

Long-term treatment with interferon-alpha can induce sarcoidosis. The connection can be stronger than earlier believed

scientific article published in June 2006

Looking into the future of sarcoidosis: what is next for treatment?

scientific article published on 09 July 2020

Löfgren's Syndrome: Diagnosis, Management, and Disease Pathogenesis.

scientific article published on 27 July 2017

Löfgren's syndrome: human leukocyte antigen strongly influences the disease course

scientific article

Mapping mononuclear phagocytes in blood, lungs, and lymph nodes of sarcoidosis patients

scientific article published on 11 February 2019

Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in Löfgren's Syndrome and Non-Löfgren's Syndrome Sarcoidosis

scientific article published on 12 September 2017

Maternal and infant outcomes in sarcoidosis pregnancy: a Swedish population-based cohort study of first births

scientific article published on 27 August 2020

Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking

scientific article published on 30 July 2020

Moving target: shifting the focus to pulmonary sarcoidosis as an autoimmune spectrum disorder

scientific article published on 11 July 2019

Neurotrophins and neurotrophin receptors in pulmonary sarcoidosis - granulomas as a source of expression

scientific article

No evidence of altered alveolar macrophage polarization, but reduced expression of TLR2, in bronchoalveolar lavage cells in sarcoidosis

scientific article

Proinflammatory Histidyl-Transfer RNA Synthetase-Specific CD4+ T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies

scientific article published on 26 November 2019

Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis

scientific article published on 29 September 2010

Proteomic Profiling Reveals Autoimmune Targets in Sarcoidosis

Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype.

scientific article published on 8 March 2018

Publisher Correction: Sarcoidosis

scientific article published on 16 July 2019

Pulmonary Extracellular Vesicles as Mediators of Local and Systemic Inflammation

scientific article

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules

scientific article

Quantitative intact proteomics investigations of alveolar macrophages in sarcoidosis

scientific article

Reduced expression of peroxisome proliferator-activated receptor alpha in BAL and blood T cells of non-löfgren's sarcoidosis patients

scientific article published on 9 April 2015

Restricted T cell receptor BV gene usage in the lungs and muscles of patients with idiopathic inflammatory myopathies

scientific article published on 01 January 2007

Review: Role of Genetics in Susceptibility and Outcome of Sarcoidosis ⬇️

scientific article published on July 27, 2010

Risk of first and recurrent serious infection in sarcoidosis: a Swedish register-based cohort study

scientific article published on 04 May 2020

Role of CD4+ T cells in sarcoidosis

scientific article published on August 2007

SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility-A Joint Analysis in Four European Populations

scientific article published on 19 April 2017

Sarcoidosis

Sarcoidosis diagnosis and treatment in Sweden: A register-based assessment of variations by region and calendar period

scientific article published on 26 November 2019

Sarcoidosis exosomes stimulate monocytes to produce pro-inflammatory cytokines and CCL2

scientific article published on 18 September 2020

Sarcoidosis incidence and prevalence: a nationwide register-based assessment in Sweden

scientific article published on 28 July 2016

Sarcoidosis mortality in Sweden: a population-based cohort study.

scientific article published on 21 February 2018

Serum protein pattern in sarcoidosis analysed by a proteomics approach

scientific article published on 01 October 2004

Sex-specific manifestations of Löfgren's syndrome

scientific article

Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.

scientific article published on 9 May 2014

Shared αβ TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome

scientific article published on 21 August 2017

Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis

scientific article published on 3 November 2015

Smoking, use of moist snuff, and risk of chronic inflammatory diseases

scientific article published on 4 March 2010

Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study

SpotLight Proteomics-A IgG-Enrichment Phenotype Profiling Approach with Clinical Implications ⬇️

scientific article published on 01 May 2019

Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers

scientific article published on 06 May 2020

Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis.

scientific article published in January 2014

Studies of T-lymphocytes in pursuit of sarcoidosis antigens

scientific article published in September 2002

T cell receptor (TCR) V gene usage in patients with systemic necrotizing vasculitis ⬇️

scientific article published on August 1, 1995

T cell receptor-Vβ repertoires in lung and blood CD4+ and CD8+ T cells of pulmonary sarcoidosis patients

scientific article

T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis

scientific article published on December 2008

T-cell activation and HLA-regulated response to smoking in the deep airways of patients with multiple sclerosis

scientific article published on 20 June 2016

T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.

scientific article published on 19 November 2015

T-lymphocyte activity in HLA-DR17 positive patients with active and clinically recovered sarcoidosis

scientific article

Th17-lineage cells in pulmonary sarcoidosis and Löfgren's syndrome: Friend or foe?

scientific article published on 5 January 2018

The lung microbiota in early rheumatoid arthritis and autoimmunity

scientific article

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells

scientific article published on 12 July 2019

T‐Cell Receptor Use in Sarcoidosisa ⬇️

scientific article published on 01 July 1995

Wheat flour exposure results in recruitment of inflammatory cells in the lungs of healthy individuals.

scientific article published in July 2003

Work ability before and after sarcoidosis diagnosis in Sweden

scientific article published on 05 October 2018

[Ankle joint arthritis in sarcoidosis--NSAID a good first choice medication]

scientific article published on 01 September 2004

[Patient with sarcoidosis and Lofgren syndrome: can the inflammatory reaction be physiologically favourable for healing?]

scientific article published on 01 October 2004

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