List of works - Tappei Takada

A common variant of organic anion transporter 4 (OAT4/SLC22A11) gene is associated with renal underexcretion type gout

scientific article

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

scientific article published on 20 January 2014

Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population

scientific article published in November 2009

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

scientific article published on January 2013

Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

scientific article published on 09 June 2014

Common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility

scientific article published on 29 August 2013

Common variant of PDZ domain containing 1 (PDZK1) gene is associated with gout susceptibility: A replication study and meta-analysis in Japanese population.

scientific article published on 30 July 2016

Common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility

scientific article

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

scientific article published on 29 November 2016

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

scientific article published on 2 February 2015

Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout

scientific article published on 8 July 2019

Identification of an exporter that regulates vitamin C supply from blood to the brain

scientific article published on 13 January 2022

Inhibitory effect of Citrus flavonoids on the in vitro transport activity of human urate transporter 1 (URAT1/SLC22A12), a renal re-absorber of urate

scientific article published on 05 February 2020

NPC1L1 Facilitates Sphingomyelin Absorption and Regulates Diet-Induced Production of VLDL/LDL-associated S1P

scientific article published on 30 August 2020

Novel function of Niemann-Pick C1-like 1 as a negative regulator of Niemann-Pick C2 protein ⬇️

scientific article published on January 30, 2012

Omega-3 Polyunsaturated Fatty Acids Inhibit the Function of Human URAT1, a Renal Urate Re-Absorber

scientific article published on 29 May 2020

Soy Isoflavone Genistein Inhibits an Axillary Osmidrosis Risk Factor ABCC11: In Vitro Screening and Fractional Approach for ABCC11-Inhibitory Activities in Plant Extracts and Dietary Flavonoids

scientific article published on 14 August 2020

Spontaneous Production of Glutathione-Conjugated Forms of 1,2-Dichloropropane: Comparative Study on Metabolic Activation Processes of Dihaloalkanes Associated with Occupational Cholangiocarcinoma

scientific article published on 7 May 2017

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients

scientific article published on 1 April 2020

The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression.

scientific article published on 29 January 2016

List of works by Tappei Takada