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List of works by Yu Toyoda

Are human ATP-binding cassette transporter C11 and earwax associated with the incidence of cholesteatoma?

scientific article published on 24 February 2018

Association Between Earwax-Determinant Genotypes and Acquired Middle Ear Cholesteatoma in a Japanese Population

scientific article

Clinical and Molecular Evidence of ABCC11 Protein Expression in Axillary Apocrine Glands of Patients with Axillary Osmidrosis

scientific article published on 15 February 2017

Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence

scientific article

Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2

scientific article

Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis

scientific journal article

Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

scientific article published on 28 November 2019

Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?

scientific article

Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2

scientific article published on 28 October 2019

Febuxostat inhibited axillary osmidrosis risk factor ATP-binding cassette transporter C11 in vitro

scientific article published on 24 July 2020

Functional Characterization of Clinically-Relevant Rare Variants in ABCG2 Identified in a Gout and Hyperuricemia Cohort

scientific article published on 18 April 2019

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

scientific article published on 29 November 2016

Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis

scientific article published on 18 April 2016

Identification of ABCG2 as an Exporter of Uremic Toxin Indoxyl Sulfate in Mice and as a Crucial Factor Influencing CKD Progression

scientific article published on 24 July 2018

Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations

scientific article published on 27 December 2016

Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice

scientific article published on 20 July 2020

Identification of a dysfunctional splicing mutation in the SLC22A12/URAT1 gene causing renal hypouricaemia type 1: a report on two families

scientific article published on 04 October 2020

Identification of an exporter that regulates vitamin C supply from blood to the brain

scientific article published on 13 January 2022

Identification of hepatic NPC1L1 as an NAFLD risk factor evidenced by ezetimibe-mediated steatosis prevention and recovery

scientific article published on 13 February 2019

Inhibitors of Human ABCG2: From Technical Background to Recent Updates With Clinical Implications

article published in 2019

Inhibitory effect of Citrus flavonoids on the in vitro transport activity of human urate transporter 1 (URAT1/SLC22A12), a renal re-absorber of urate

scientific article published on 05 February 2020

Investigation of the transport of xanthine dehydrogenase inhibitors by the urate transporter ABCG2.

scientific article published on 22 November 2017

Multiple common and rare variants of ABCG2 cause gout

scientific article published on 29 August 2017

NPC1L1 is a key regulator of intestinal vitamin K absorption and a modulator of warfarin therapy

scientific article published on February 2015

Novel dysfunctional variant in ABCG2 as a cause of severe tophaceous gout: biochemical, molecular genetics and functional analysis

scientific article published on 30 September 2015

Omega-3 Polyunsaturated Fatty Acids Inhibit the Function of Human URAT1, a Renal Urate Re-Absorber

scientific article published on 29 May 2020

Organic cation transporter/solute carrier family 22a is involved in drug transfer into milk in mice

scientific article published on 29 August 2014

Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet

scientific article published on 28 December 2019

Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretion

scientific article published in 2012

Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure

scientific article published on October 1, 2010

Pharmacogenomics of Human ABC Transporters: Detection of Clinically Important SNPs by SmartAmp2 Method

scientific article published on April 1, 2011

Prediction of Drug Transfer into Milk Considering Breast Cancer Resistance Protein (BCRP)-Mediated Transport

scientific article published on 19 February 2015

Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flp recombinase system

scientific article published on January 2010

Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose Condition

scientific article

Soy Isoflavone Genistein Inhibits an Axillary Osmidrosis Risk Factor ABCC11: In Vitro Screening and Fractional Approach for ABCC11-Inhibitory Activities in Plant Extracts and Dietary Flavonoids

scientific article published on 14 August 2020

Spontaneous Production of Glutathione-Conjugated Forms of 1,2-Dichloropropane: Comparative Study on Metabolic Activation Processes of Dihaloalkanes Associated with Occupational Cholangiocarcinoma

scientific article published on 7 May 2017

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients

scientific article published on 1 April 2020

Ubiquitin-Mediated Proteasomal Degradation of ABC Transporters: a New Aspect of Genetic Polymorphisms and Clinical Impacts

scientific article published on May 12, 2011