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List of works by Sara Teresinha Olalla Saad

(-)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1

scientific article published on 27 April 2021

3D Scaffolds to Model the Hematopoietic Stem Cell Niche: Applications and Perspectives

scientific article published on 26 January 2021

51Cr-EDTA measurements of the glomerular filtration rate in patients with sickle cell anaemia and minor renal damage.

scientific article published in December 2006

A novel beta-globin variant: Hb Poços de Caldas [beta 61(E5)Lys-->Gln].

scientific article

ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells

scientific article published on 15 December 2014

ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells

scientific article published on 12 April 2014

ANKHD1, ankyrin repeat and KH domain containing 1, is overexpressed in acute leukemias and is associated with SHP2 in K562 cells

scientific article

ARHGAP10, a novel human gene coding for a potentially cytoskeletal Rho-GTPase activating protein

scientific article

ARHGAP21 associates with FAK and PKCzeta and is redistributed after cardiac pressure overload

scientific article

ARHGAP21 protein, a new partner of α-tubulin involved in cell-cell adhesion formation and essential for epithelial-mesenchymal transition

scientific article

Abnormal Hedgehog pathway in myelodysplastic syndrome and its impact on patients' outcome.

scientific article published on 20 August 2015

Altered red cell and platelet adhesion in hemolytic diseases: Hereditary spherocytosis, paroxysmal nocturnal hemoglobinuria and sickle cell disease.

scientific article published on 21 September 2013

An efficient protocol for the generation of monocyte derived dendritic cells using serum-free media for clinical applications in post remission AML patients.

scientific article published in January 2014

An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

article

An update on arginine in sickle cell disease

scientific article published on 20 March 2019

Apoptosis-regulating proteins and prognosis in diffuse large B cell non-Hodgkin's lymphomas

scientific article published on 01 January 2002

Artemisinin-type drugs for the treatment of hematological malignancies

scientific article published on 03 November 2020

Association of the G-463A myeloperoxidase polymorphism with infection in sickle cell anemia

scientific article published on 01 July 2005

BCR-ABL binds to IRS-1 and IRS-1 phosphorylation is inhibited by imatinib in K562 cells

scientific article published on January 2003

BNIP3L in myelodysplastic syndromes and acute myeloid leukemia: impact on disease outcome and cellular response to decitabine

scientific article published on 21 July 2016

BRD4 Inhibition Enhances Azacitidine Efficacy in Acute Myeloid Leukemia and Myelodysplastic Syndromes

scientific article published on 29 January 2019

Band 3Tambaú: a de novo mutation in the AE1 gene associated with hereditary spherocytosis. Implications for anion exchange and insertion into the red blood cell membrane

scientific article published in May 2005

Bone marrow progenitor cells from chemically exposed workers display an intrinsic ability for autonomous proliferation

scientific article published on 01 January 2005

Both interleukin-3 and interleukin-6 are necessary for better ex vivo expansion of CD133+ cells from umbilical cord blood

scientific article published on 01 March 2010

CATS (FAM64A) abnormal expression reduces clonogenicity of hematopoietic cells

scientific article published on 31 August 2016

CXCR4hi effector neutrophils in sickle cell anemia: potential role for elevated circulating serotonin (5-HT) in CXCR4hi neutrophil polarization

scientific article published on 31 August 2020

CXCR7 is highly expressed in acute lymphoblastic leukemia and potentiates CXCR4 response to CXCL12.

scientific article published on 31 January 2014

CXCR7 participates in CXCL12-mediated migration and homing of leukemic and normal hematopoietic cells

scientific article published on 12 February 2018

Causes of incidental neutropenia in adulthood.

scientific article published on 29 June 2006

Characterisation of a new splice variant of MASK-BP3(ARF) and MASK human genes, and their expression patterns during haematopoietic cell differentiation

scientific article

Characterization of a novel decellularized bone marrow scaffold as an inductive environment for hematopoietic stem cells

scientific article published on 01 March 2019

Chronic liver abnormalities in sickle cell disease: a clinicopathological study in 70 living patients

scientific article published on 03 September 2007

Coinheritance of Hb Bristol-Alesha [β67(E11)Val→Met; HBB: c.202G>A] and the α212 Patchwork Allele in a Brazilian Child with Severe Congenital Hemolytic Anemia

scientific article published on 01 May 2017

Consensus statement for diagnosis and treatment of paroxysmal nocturnal haemoglobinuria

scientific article published on 06 July 2020

Cytokine polymorphisms in sickle cell disease and the relationship with cytokine expression

scientific article

DNA-based typing of blood groups for the management of multiply-transfused sickle cell disease patients

scientific article published on 01 February 2002

DNAase I hypersensitive site 3' to the beta-globin gene cluster containing two TAA insertions and a G-->A polymorphism is predominantly associated with the beta+-thalassemia IVS-I-6 (T-->C) mutation

scientific article published on 01 January 2005

DNAase I hypersensitive site 3' to the beta-globin gene cluster contains a TAA insertion specific for beta(S)-Benin haplotype

scientific article published on 01 March 2002

Deferasirox associated with liver failure and death in a sickle cell anemia patient homozygous for the -1774delG polymorphism in the Abcc2 gene

scientific article published on 15 June 2017

Detection and possible prognostic relevance of p53 gene mutations in diffuse large B-cell lymphoma. An analysis of 51 cases and review of the literature.

scientific article published in October 2004

Determinants of change in paternal smoking trends during pregnancy in Lebanon

scientific article published on 01 January 2010

Differences in heme and hemopexin content in lipoproteins from patients with sickle cell disease

scientific article published on 14 August 2018

Differential profile of CDKN1A and TP53 expressions in bone marrow mesenchymal stromal cells from myeloid neoplasms.

scientific article published on 6 August 2016

Differential profile of PIP4K2A expression in hematological malignancies.

scientific article published on 30 June 2015

Differentiation of C2C12 myoblasts is critically regulated by FAK signaling.

scientific article

Diskitis in toddlers revisited

scientific article published in March 2010

Distinct expression profiles of MSI2 and NUMB genes in myelodysplastic syndromes and acute myeloid leukemia patients.

scientific article

Downregulation of IRS2 in myelodysplastic syndrome: A possible role in impaired hematopoietic cell differentiation ⬇️

scientific article published on March 31, 2012

Echocardiografic abnormalities in patients with sickle cell/β-thalassemia do not depend on the β-thalassemia phenotype

scientific article published on 31 December 2018

Effect of cytokines and chemokines on sickle neutrophil adhesion to fibronectin.

scientific article published on January 2005

Effectiveness of a home-based therapeutic exercise program on lower back pain and functionality in Sickle Cell Disease (SCD) patients

scientific article published on 25 June 2020

Effects of RhoA and RhoC upon the sensitivity of prostate cancer cells to glutamine deprivation

scientific article published on 18 November 2018

Effects of home-based inspiratory muscle training on sickle cell disease (SCD) patients

scientific article published on 14 September 2020

Elevated plasma levels and platelet-associated expression of the pro-thrombotic and pro-inflammatory protein, TNFSF14 (LIGHT), in sickle cell disease.

scientific article published on 6 July 2012

Enalapril therapy and cardiac remodelling in sickle cell disease patients

scientific article published in October 2008

Exosomes in the serum of Acute Myeloid Leukemia patients induce dendritic cell tolerance: Implications for immunotherapy

scientific article published on 10 February 2019

Expression of alpha-hemoglobin stabilizing protein gene during human erythropoiesis

scientific article published in February 2004

Expression of new red cell-related genes in erythroid differentiation

scientific article

FMNL1 promotes proliferation and migration of leukemia cells

scientific article published on 25 June 2013

Follow-up of sickle cell disease patients with priapism treated by hydroxyurea

scientific article

Gene expression analysis of the Brazilian type of hereditary persistence of fetal hemoglobin: identification of genes that could be related to γ-globin activation.

scientific article published on 19 August 2013

Granulocytic adhesive interactions and their role in sickle cell vaso-occlusion

scientific article

Guidelines on neonatal screening and painful vaso-occlusive crisis in sickle cell disease: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular: Project guidelines: Associação Médica Brasileira - 2016.

scientific article published on 08 April 2016

Guidelines on the treatment of anemia of chronic renal failure using recombinant human erythropoietin: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Guidelines Project: Associação Médica Brasileira - 2014.

scientific article published on October 2014

Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.

scientific article published on 10 November 2016

Hematopoietic defects in response to reduced Arhgap21.

scientific article published on 23 November 2017

High expression of FMNL1 protein in T non-Hodgkin's lymphomas

scientific article published on 21 February 2006

High expression of apoptosis-regulating proteins in Burkitt's lymphomas

scientific article published on 01 March 2002

High levels of human gamma-globin are expressed in adult mice carrying a transgene of the Brazilian type of hereditary persistence of fetal hemoglobin ((A)gamma -195)

scientific article published on 01 January 2009

Highlight article: Whole-exome sequencing indicates FLG2 variant associated with leg ulcers in Brazilian sickle cell anemia patients

scientific article published on 12 May 2019

Human leukocyte formin: a novel protein expressed in lymphoid malignancies and associated with Akt.

scientific article

Hypocholesterolemia and dysregulated production of angiopoietin-like proteins in sickle cell anemia patients

scientific article published on 01 May 2019

IL10 inversely correlates with the percentage of CD8⁺ cells in MDS patients

scientific article published on 28 February 2013

IL32 expression in peripheral blood CD3+ cells from myelodysplastic syndromes patients

IL4 and IFNalpha generation of dendritic cells reveals great migratory potential and NFkB and cJun expression in IL4DCs

scientific article published on 11 July 2013

IRAK1 expression in bone marrow cells does not impact patient outcomes in myelodysplastic syndromes.

scientific article published on 28 November 2017

Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster

scientific article

Immunophenotyping in myelodysplastic syndromes can add prognostic information to well-established and new clinical scores

scientific article

Impaired red cell deformability in iron deficient subjects

scientific article

In vitro microfluidic model for the study of vaso-occlusive processes

scientific article published on 11 November 2014

Increased adhesive properties of eosinophils in sickle cell disease

scientific article

Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation

scientific article published on 6 March 2008

Increased adhesive properties of platelets in sickle cell disease: roles for alphaIIb beta3-mediated ligand binding, diminished cAMP signalling and increased phosphodiesterase 3A activity

scientific article published on 5 February 2010

Increased levels of soluble ICAM-1 in the plasma of sickle cell patients are reversed by hydroxyurea

scientific article

Increased soluble guanylate cyclase activity in the red blood cells of sickle cell patients

scientific article published in February 2004

Inhibition of caspase-dependent spontaneous apoptosis via a cAMP-protein kinase A dependent pathway in neutrophils from sickle cell disease patients

scientific article published on 17 August 2007

Inhibition of phosphodiesterase 9A reduces cytokine-stimulated in vitro adhesion of neutrophils from sickle cell anemia individuals.

scientific article published on 20 February 2011

LEF1-AS1, long non-coding RNA, inhibits proliferation in myeloid malignancy

scientific article published on 15 February 2019

Lack of Arg972 polymorphism in the IRS1 gene in Parakanã Brazilian Indians

scientific article

Lithium, a classic drug in psychiatry, improves nilotinib-mediated antileukemic effects.

scientific article published on 12 January 2018

Liver transplantation in a patient with S(beta)o-thalassemia

scientific article published on 01 September 2002

Low Ten-eleven-translocation 2 (TET2) transcript level is independent of TET2 mutation in patients with myeloid neoplasms.

scientific article published on 16 March 2016

Low expression of tissue inhibitor of metalloproteinase-2 may be associated with high-risk myelodysplastic syndrome

scientific article published on 28 September 2012

MDR-1 and GST polymorphisms are involved in myelodysplasia progression.

scientific article published on 17 May 2013

Maturation-associated immunophenotypic abnormalities in bone marrow B-lymphocytes in myelodysplastic syndromes

scientific article published on 7 July 2005

Mesenchymal stromal cells from adipose tissue attached to suture material enhance the closure of enterocutaneous fistulas in a rat model

scientific article published on 11 October 2014

Mild hemolysis in a girl with G6PD Sumaré (class I variant) associated with G6PD A− ⬇️

scientific article published on May 1, 2003

Molecular characterization of hemoglobin alpha-D chains from Geochelone carbonaria and Geochelone denticulata land turtles

scientific article published on 01 February 2003

Molecular effects of the phosphatidylinositol-3-kinase inhibitor NVP-BKM120 on T and B-cell acute lymphoblastic leukaemia.

scientific article published on 31 July 2015

Molecular heterogeneity of G6PD deficiency in an Amazonian population and description of four new variants

scientific article published in May 2002

Molecular matching for Rh and K reduces red blood cell alloimmunisation in patients with myelodysplastic syndrome.

scientific article

Motivating medical students to learn basic science concepts using chronic myeloid leukemia as an integration theme

scientific article published on 16 December 2014

Multitarget effects of quercetin in leukemia.

scientific article published on 7 October 2014

Myelodysplastic syndrome with synchronous gastric cancer: when the symptoms suggest something else

scientific article published on 17 July 2014

Natural Type II Collagen Hydrogel, Fibrin Sealant, and Adipose-Derived Stem Cells as a Promising Combination for Articular Cartilage Repair

scientific article published on 29 November 2016

Neuroprotection and immunomodulation by xenografted human mesenchymal stem cells following spinal cord ventral root avulsion

scientific article

Novel mutations associated with pyruvate kinase deficiency in Brazil

scientific article published on 26 November 2017

Obesity and inflammation and the effect on the hematopoietic system

scientific article published on March 2014

Overexpression and Characterization of The C-Terminal Domain of Human Siva1, A Proapoptotic Factor and Cytoskeleton Binding Protein.

scientific article published on 26 October 2015

PIP4KIIA and beta-globin: transcripts differentially expressed in reticulocytes and associated with high levels of Hb H in two siblings with Hb H disease

scientific article published on 27 July 2009

PIPKIIα is widely expressed in hematopoietic-derived cells and may play a role in the expression of alpha- and gamma-globins in K562 cells.

scientific article

PTK2 and PTPN11 expression in myelodysplastic syndromes.

scientific article published on October 2013

Pancytopenia in untreated patients with Graves' disease

scientific article published on 01 April 2006

Phylogenetic analysis of RhoGAP domain-containing proteins

scientific article published on August 2006

Pilot randomized controlled trial to evaluate the effect of aquatic and land physical therapy on musculoskeletal dysfunction of sickle cell disease patients.

scientific article

Platelet associated IgG may be related with thrombocytopenia in patients with myelodysplastic syndromes

scientific article

Polymorphisms of interleukin-1 gene complex, IL6 and tumour necrosis factor genes in chronic idiopathic neutropenia of adults.

scientific article

Practical approach to the child presenting with back pain

scientific article published on 22 May 2010

Prevalence of Bartonella spp. Infection in Patients with Sickle Cell Disease

scientific article published on 03 February 2020

Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice.

scientific article

Progesterone upregulates GATA-1 on erythroid progenitors cells in liquid culture

scientific article published on September 2002

Quelação oral de ferro na Beta-Talassemia

Rabbit antithymocyte globulin dose does not affect response or survival as first-line therapy for acquired aplastic anemia: a multicenter retrospective study

scientific article published on 05 July 2018

Reactive oxygen species production triggers green tea-induced anti-leukaemic effects on acute promyelocytic leukaemia model

scientific article

Recombinant erythropoietin as alternative to red cell transfusion in sickle cell disease

scientific article published on 29 January 2019

Red blood cells microparticles are associated with hemolysis markers and may contribute to clinical events among sickle cell disease patients

scientific article published on 06 September 2019

Reduced expression of FLIP SHORT in bone marrow of low risk myelodysplastic syndrome.

scientific article

Reduced expression of NR4A1 activates glycolytic pathway in acute promyelocytic leukemia cells.

scientific article

Reduced rate of sickle-related complications in Brazilian patients carrying HbF-promoting alleles at the BCL11A and HMIP-2 loci.

scientific article published on 16 February 2016

Reduction of AHSP synthesis in hemin-induced K562 cells and EPO-induced CD34(+) cells leads to alpha-globin precipitation, impairment of normal hemoglobin production, and increased cell death

scientific article published on 7 January 2008

Regulation of chondrogenesis by transforming growth factor-beta 3 and insulin-like growth factor-1 from human mesenchymal umbilical cord blood cells

scientific article published on 15 May 2010

Regulation of the GATA3 promoter by human T-cell lymphotropic virus type I Tax protein

scientific article published on December 2004

Risk factors for conjunctival and retinal vessel alterations in sickle cell disease

scientific article published on 01 April 2006

Role for cAMP-protein kinase A signalling in augmented neutrophil adhesion and chemotaxis in sickle cell disease

scientific article

S100A8 acts as an autocrine priming signal for heme-induced human Mϕ pro-inflammatory responses in hemolytic inflammation

scientific article published on 15 May 2019

SEMA3A partially reverses VEGF effects through binding to neuropilin-1.

scientific article

Serine peptidase inhibitor Kunitz type 2 (SPINT2) in cancer development and progression.

scientific article published on 26 February 2018

Serine protease inhibitor kunitz-type 2 is downregulated in myelodysplastic syndromes and modulates cell-cell adhesion

scientific article

Sickle cell disease serum induces NADPH enzyme subunit expression and oxidant production in leukocytes

scientific article published on December 2010

Sickle cell/β-thalassemia: Comparison of Sβ0 and Sβ+ Brazilian patients followed at a single institution

scientific article published on 28 May 2016

Simple fluorescent PCR method for detection of large deletions in the beta-globin gene cluster

scientific article published in March 2003

Small Particles, Big Effects: The Interplay Between Exosomes and Dendritic Cells in Antitumor Immunity and Immunotherapy

scientific article published on 16 December 2019

Stathmin 1 expression in plasma cell neoplasms

scientific article published on 11 March 2017

Stathmin 1 in normal and malignant hematopoiesis.

scientific article published on December 2014

Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2V617F cells

scientific article published on 24 August 2015

Stathmin 1 is involved in the highly proliferative phenotype of high-risk myelodysplastic syndromes and acute leukemia cells.

scientific article

TET2 is upregulated during erythroid differentiation of CD34+ cells from healthy donors and myelodysplastic syndrome patients

Technetium-99m-dimercaptosuccinic acid renal scintigraphy and single photon emission computed tomography/computed tomography in patients with sickle cell disease

scientific article published on 01 November 2019

Ten-eleven-translocation 2 (TET2) is downregulated in myelodysplastic syndromes

scientific article published on 01 October 2014

The CALM and CALM/AF10 interactor CATS is a marker for proliferation

scientific article published on 4 September 2008

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

scientific article

The Cratylia mollis seed lectin induces membrane permeability transition in isolated rat liver mitochondria and a cyclosporine a-insensitive permeability transition in Trypanosoma cruzi mitochondria

scientific article published in July 2014

The Gly972Arg polymorphism in insulin receptor substrate-1 is associated with decreased birth weight in a population-based sample of Brazilian newborns

scientific article published in March 2002

The U2AF homology motif kinase 1 (UHMK1) is upregulated upon hematopoietic cell differentiation

scientific article published on 4 January 2018

The challenges of handling deferasirox in sickle cell disease patients older than 40 years

scientific article published on 01 December 2019

The effects of exchange transfusion for prevention of complications during pregnancy of sickle hemoglobin C disease patients.

scientific article published on 3 September 2015

The polyphenol quercetin induces cell death in leukemia by targeting epigenetic regulators of pro-apoptotic genes

article

Therapy with hydroxyurea is associated with reduced adhesion molecule gene and protein expression in sickle red cells with a concomitant reduction in adhesive properties.

scientific article

Transfusion service management of sickle-cell disease patients

scientific article

Up-regulation of NADPH oxidase components and increased production of interferon-gamma by leukocytes from sickle cell disease patients

article

Up-regulation of SPINT2/HAI-2 by Azacytidine in bone marrow mesenchymal stromal cells affects leukemic stem cell survival and adhesion

scientific article published on 28 November 2018

Useful properties of undifferentiated mesenchymal stromal cells and adipose tissue as the source in liver-regenerative therapy studied in an animal model of severe acute fulminant hepatitis

scientific article

Viability of umbilical cord blood mononuclear cell subsets until 96 hours after collection

scientific article published on 16 January 2013

YAP1 expression in myelodysplastic syndromes and acute leukemias.

scientific article published on 10 March 2014

alpha-cardiac actin (ACTC) binds to the band 3 (AE1) cardiac isoform

scientific journal article

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