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List of works by Simon O'Carroll

A Macroscopic Diffusion-Based Gradient Generator to Establish Concentration Gradients of Soluble Molecules Within Hydrogel Scaffolds for Cell Culture

scientific article published on 18 September 2019

A key role for connexin hemichannels in spreading ischemic brain injury

scientific article published on January 2013

A model for ex vivo spinal cord segment culture--a tool for analysis of injury repair strategies

scientific article published on 21 July 2010

Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers.

scientific article published on 27 October 2017

Analysis of Melanoma Secretome for Factors That Directly Disrupt the Barrier Integrity of Brain Endothelial Cells

scientific article published on 01 November 2020

Application of xCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time.

scientific article

Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury

scientific article published on 08 April 2019

Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury

scientific article published on 07 February 2020

Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice

scientific article

Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products

scientific article published on 21 September 2017

Bradykinin receptor-1 activation induces inflammation and increases the permeability of human brain microvascular endothelial cells

scientific article published on 09 September 2019

CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons

scientific article published on 10 May 2022

Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats.

scientific article published on 19 July 2017

Characterizing the mode of action of extracellular Connexin43 channel blocking mimetic peptides in an in vitro ischemia injury model.

scientific article published on 2 November 2016

Connexin 43 mimetic peptides reduce swelling, astrogliosis, and neuronal cell death after spinal cord injury.

scientific article published in May 2008

Connexin hemichannel blockade improves outcomes in a model of fetal ischemia

scientific article published on January 2012

Connexin hemichannel induced vascular leak suggests a new paradigm for cancer therapy

scientific article published on 15 February 2014

Connexin43 Expression and Associated Chronic Inflammation Presages the Development of Cerebral Radiation Necrosis

scientific article published on 24 May 2020

Connexin43 Mimetic Peptide Improves Retinal Function and Reduces Inflammation in a Light-Damaged Albino Rat Model

scientific article published on August 2016

Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury.

scientific article published on 8 February 2013

Connexin43 mimetic peptide reduces vascular leak and retinal ganglion cell death following retinal ischaemia

scientific article published in February 2012

Connexins and Pannexins in cerebral ischemia

scientific article published on 24 March 2017

Determining Neurotrophin Gradients in Vitro To Direct Axonal Outgrowth Following Spinal Cord Injury

scientific article published on 26 December 2019

Dose-dependent protective effect of connexin43 mimetic peptide against neurodegeneration in an ex vivo model of epileptiform lesion.

scientific article

ECIS technology reveals that monocytes isolated by CD14+ve selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1β activated endothelium in comparison to TNFα.

scientific article published on 21 July 2017

Extracellular signal-regulated kinase involvement in human astrocyte migration.

scientific article

Gap junction proteins and their role in spinal cord injury

scientific article

Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta.

scientific article

IL-6 stimulates a concentration-dependent increase in MCP-1 in immortalised human brain endothelial cells

scientific article published on 3 March 2016

Image-based high-throughput quantification of cellular fat accumulation.

scientific article published on October 2007

In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology

scientific article published on 11 October 2018

Make it simple: long-term stable gradient generation in a microfluidic microdevice

scientific article published on 26 July 2019

Non-invasive neuromodulation for bowel, bladder and sexual restoration following spinal cord injury: A systematic review

scientific article published on 12 April 2020

Nuclear PLCbeta1 is required for 3T3-L1 adipocyte differentiation and regulates expression of the cyclin D3-cdk4 complex

scientific journal article

Nuclear prostaglandin receptors: role in pregnancy and parturition?

scientific article published on February 2004

Optimisation of glutathione conjugation to liposomes quantified with a validated HPLC assay

scientific article published on 20 June 2019

Optimised techniques for high-throughput screening of differentiated SH-SY5Y cells and application for neurite outgrowth assays

scientific article published on 14 December 2021

Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells.

scientific article published on 8 July 2015

Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology

scientific article published on 15 April 2019

Receptor for Advanced Glycation End Products (RAGE) is Expressed Predominantly in Medium Spiny Neurons of tgHD Rat Striatum.

scientific article published on 3 April 2018

Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors

scientific article published on 27 January 2016

Spatiotemporal changes in Cx30 and Cx43 expression during neuronal differentiation of P19 EC and NT2/D1 cells.

scientific article published on 30 August 2013

Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier

scientific article

Stretchable Electronics Based on Laser Structured, Vapor Phase Polymerized PEDOT/Tosylate

scientific article published on 25 July 2020

Systemic Administration of Connexin43 Mimetic Peptide Improves Functional Recovery after Traumatic Spinal Cord Injury in Adult Rats

scientific article

The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier

scientific article published on 04 July 2018

The functional and inflammatory response of brain endothelial cells to Toll-Like Receptor agonists.

scientific article published on 4 July 2018

The involvement of extracellular vesicles in the transcytosis of nanoliposomes through brain endothelial cells, and the impact of liposomal pH-sensitivity

scientific article published on 01 January 2022

The role of nuclear lipid signalling in adipocyte differentiation

2005 doctoral thesis by Simon Joseph O'Carroll at University of Auckland

The role of receptor for advanced glycation end products (RAGE) in neuronal differentiation

scientific article

The use of connexin-based therapeutic approaches to target inflammatory diseases.

scientific article published on January 2013

Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels.

scientific article published on 30 May 2017

Unique and shared inflammatory profiles of human brain endothelia and pericytes.

scientific article

Upregulation of pannexin-1 hemichannels explains the apparent death of the syncytiotrophoblast during human placental explant culture

scientific article published on 04 March 2020

Vascular degeneration in Parkinson's disease.

scientific article published on 13 September 2012

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