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List of works by Mark R Middleton

A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumours

scientific article

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors ⬇️

scientific article published on September 28, 2011

Diagnosis and treatment of Merkel Cell Carcinoma. European consensus-based interdisciplinary guideline.

scientific article published on 06 August 2015

Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guideline

scientific article

Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8<sup>+</sup> T cell clone size and cytotoxicity

scientific article published on 01 October 2021

Intratumoural immunotherapies for unresectable and metastatic melanoma: current status and future perspectives

scientific article published on 27 July 2020

Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma

scientific article published on 10 February 2020

Single cell RNA-seq reveals profound transcriptional similarity between Barrett's oesophagus and oesophageal submucosal glands

scientific article published in Nature Communications

Tebentafusp, a TCR/anti-CD3 bispecific fusion protein targeting gp100, potently activated anti-tumor immune responses in patients with metastatic melanoma

scientific article published on 18 August 2020

The Circulating Transcriptome as a Source of Biomarkers for Melanoma

scientific article published on 10 January 2019

Tumour gene expression signature in primary melanoma predicts long-term outcomes

scientific article published on 18 February 2021

VCAM-1 targeted magnetic resonance imaging enables detection of brain micrometastases from different primary tumours

scientific article published on 02 November 2018

ctDNA monitoring using patient-specific sequencing and integration of variant reads

scientific article published on 01 June 2020

sFRP2 Supersedes VEGF as an Age-related Driver of Angiogenesis in Melanoma, Affecting Response to Anti-VEGF Therapy in Older Patients

scientific article published on 23 October 2020

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