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List of works by Matthias Rottmann

Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures

scientific article

Cell Penetration, Herbicidal Activity, and in-vivo-Toxicity of Oligo-Arginine Derivatives and of Novel Guanidinium-Rich Compounds Derived from the Biopolymer Cyanophycin

scientific article published on 01 October 2018

Deorphaning pyrrolopyrazines as potent multi-target antimalarial agents

scientific article published on 4 June 2014

Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

scientific article published on 27 February 2020

Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development

scientific article published on 10 March 2020

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection

scientific article published on 13 September 2019

Imidazolopiperazines: hit to lead optimization of new antimalarial agents.

scientific article published on 23 June 2011

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

scientific article published on 20 March 2019

Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model

scientific article

Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs.

scientific article

Potent Inhibitors of Malarial Aspartic Proteases, the Plasmepsins, by Hydroformylation of Substituted 7‐Azanorbornenes

scientific article published on November 19, 2012

Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold

scientific article published on 14 April 2018

Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor

scientific article published on 24 March 2020

Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD

scientific article

Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria.

scientific article published on July 2010

The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector

scientific article published on April 16, 2012