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List of works by Huy Ong

A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism

scientific article published in 2016

A Linear Fragment of Unacylated Ghrelin (UAG) Protects Against Myocardial Ischemia/Reperfusion Injury in Mice in a Growth Hormone Secretagogue Receptor-Independent Manner

A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages

scientific article

A growth hormone-releasing peptide promotes mitochondrial biogenesis and a fat burning-like phenotype through scavenger receptor CD36 in white adipocytes

scientific article published on 30 November 2006

A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor up-regulates sterol transporters and cholesterol efflux in macrophages through a peroxisome proliferator-activated receptor gamma-dependent pathway

scientific article published on 07 September 2006

Activation of CD36 inhibits and induces regression of inflammatory corneal neovascularization.

scientific article

Adiponectin has a pivotal role in the cardioprotective effect of CP-3(iv), a selective CD36 azapeptide ligand, after transient coronary artery occlusion in mice

scientific article published on 10 October 2017

Atheroprotective and atheroregressive potential of azapeptide derivatives of GHRP-6 as selective CD36 ligands in apolipoprotein E-deficient mice

scientific article published on 06 July 2020

Atheroregressive Potential of the Treatment with a Chimeric Monoclonal Antibody against Sulfated Glycosaminoglycans on Pre-existing Lesions in Apolipoprotein E-Deficient Mice.

scientific article published in November 2017

Azapeptide analogues of the growth hormone releasing peptide 6 as cluster of differentiation 36 receptor ligands with reduced affinity for the growth hormone secretagogue receptor 1a.

scientific article

Azasulfurylpeptide Modulation of CD36-Mediated Inflammation Without Effect on Neovascularization

scientific article published on 22 October 2018

CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice

scientific article published on 01 January 2019

CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents

scientific article (publication date: February 2008)

CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits.

scientific article published on December 2010

CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages

scientific article published on 17 April 2009

Cardiac and peripheral actions of growth hormone and its releasing peptides: relevance for the treatment of cardiomyopathies

scientific article

Diversity-Oriented Synthesis of Cyclic Azapeptides by A3 -Macrocyclization Provides High-Affinity CD36-Modulating Peptidomimetics.

scientific article published on 16 January 2017

Dynamic Chirality in the Mechanism of Action of Allosteric CD36 Modulators of Macrophage-Driven Inflammation

scientific article published on 13 December 2019

EP 80317, a CD36 selective ligand, promotes reverse cholesterol transport in apolipoprotein E-deficient mice ⬇️

scientific article published on June 14, 2013

EP 80317, a ligand of the CD36 scavenger receptor, protects apolipoprotein E-deficient mice from developing atherosclerotic lesions

scientific article published on 25 August 2005

EP 80317, a selective CD36 ligand, shows cardioprotective effects against post-ischaemic myocardial damage in mice.

scientific article

EP80317 Restrains Inflammation and Mortality Caused by Scorpion Envenomation in Mice

scientific article published on 01 March 2019

Effect of chronic treatment with bovine recombinant growth hormone on cardiac dysfunction and lesion progression in UM-X7.1 cardiomyopathic hamsters

scientific article

Exploring side-chain diversity by submonomer solid-phase aza-peptide synthesis

scientific article published on 01 August 2009

GPR103b functions in the peripheral regulation of adipogenesis.

scientific article

Genetic ablation of CD36 induces age-related corneal neovascularization

scientific article published on 01 October 2008

Ghrelin Modulates Physiologic and Pathologic Retinal Angiogenesis through GHSR-1a ⬇️

scientific article published on July 23, 2011

Identification of the growth hormone-releasing peptide binding site in CD36: a photoaffinity cross-linking study

scientific article published on September 2004

Immunometabolic modulation of retinal inflammation by CD36 ligand

scientific article published on 09 September 2019

Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity

scientific article published on 29 August 2007

Induction of anti-anti-idiotype antibodies against sulfated glycosaminoglycans reduces atherosclerosis in apolipoprotein E-deficient mice

scientific article published on 18 October 2012

Influences of Histidine-1 and Azaphenylalanine-4 on the Affinity, Anti-inflammatory, and Antiangiogenic Activities of Azapeptide Cluster of Differentiation 36 Receptor Modulators.

scientific article

Modified peptide monolayer binding His-tagged biomolecules for small ligand screening with SPR biosensors.

scientific article

Obestatin regulates adipocyte function and protects against diet-induced insulin resistance and inflammation.

scientific article published on 17 May 2012

PCSK9 Induces CD36 Degradation and Affects Long-Chain Fatty Acid Uptake and Triglyceride Metabolism in Adipocytes and in Mouse Liver

scientific article published on 22 October 2015

Positional scanning for peptide secondary structure by systematic solid-phase synthesis of amino lactam peptides

scientific article

Postnatal weight gain modifies severity and functional outcome of oxygen-induced proliferative retinopathy.

scientific article

Potential peptides in atherosclerosis therapy

scientific article

Propranolol Attenuates Proangiogenic Activity of Mononuclear Phagocytes: Implication in Choroidal Neovascularization

scientific article published on 01 November 2019

Pyroglutamylated RF-amide peptide (QRFP) gene is regulated by metabolic endotoxemia

scientific article

QRFP-43 inhibits lipolysis by preventing ligand-induced complex formation between perilipin A, caveolin-1, the catalytic subunit of protein kinase and hormone-sensitive lipase in 3T3-L1 adipocytes

scientific article published on 9 February 2015

RFamide peptides 43RFa and 26RFa both promote survival of pancreatic β-cells and human pancreatic islets but exert opposite effects on insulin secretion.

scientific article published on 12 March 2014

Recombinant bovine growth hormone-induced reduction of atrial natriuretic peptide is associated with improved left ventricular contractility and reverse remodeling in cardiomyopathic UM-X7.1 hamsters with congestive heart failure

scientific article published on 5 February 2007

Solid-Phase Azopeptide Diels-Alder Chemistry for Aza-pipecolyl Residue Synthesis To Study Peptide Conformation

scientific article published on 26 April 2019

Structure-activity analysis of the growth hormone secretagogue GHRP-6 by alpha- and beta-amino gamma-lactam positional scanning

scientific article published on 01 January 2010

Structure-activity relationships of GHRP-6 azapeptide ligands of the CD36 scavenger receptor by solid-phase submonomer azapeptide synthesis

scientific article published on 21 July 2011

Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36)

scientific article published on 23 July 2020

The CD36 Ligand-Promoted Autophagy Protects Retinal Pigment Epithelial Cells from Oxidative Stress

scientific article published on 28 March 2021

The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation

scientific article

Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration

scientific article published on 27 November 2005

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