List of works by Mario F Fraga

A DNA methylation fingerprint of 1628 human samples

scientific article

A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

scientific article

A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer

scientific article published on September 2006

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

scientific article

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2

article

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

scientific article

Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes.

scientific article published on 11 December 2017

Capillary electrophoresis-based method to quantitate DNA–protein interactions ⬇️

scientific article published on June 15, 2003

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

scientific article

Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.

scientific article published in September 2006

Combinatorial effects of splice variants modulate function of Aiolos

scientific article

DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers

scientific article published on 30 March 2015

DNA Methylomes and Epigenetic Age Acceleration Associations with Poor Metabolic Control in T1D

scientific article published on 24 December 2020

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer.

scientific article

DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E.

scientific article

DNA methylation reprogramming of human cancer cells by expression of a plant 5-methylcytosine DNA glycosylase.

scientific article published on 13 December 2017

DNA methylation signatures identify biologically distinct thyroid cancer subtypes.

scientific article published on 10 May 2013

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells

scientific article published on 12 December 2012

Epigenetic alterations in endocrine-related cancer.

scientific article

Epigenetic differences arise during the lifetime of monozygotic twins

scientific article

Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells

scientific article published on 13 March 2007

Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis

scientific article published on 01 July 2019

Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies

scientific article

Epigenetic regulation of the immune system in health and disease ⬇️

scientific article published on December 1, 2010

Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications.

scientific article

Genetic and non-genetic predictors of LINE-1 methylation in leukocyte DNA.

scientific article published on 3 April 2013

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells

scientific article

Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study

scientific article published on 12 March 2008

HERG1A potassium channel is the predominant isoform in head and neck squamous cell carcinomas: evidence for regulation by epigenetic mechanisms

scientific article published on 20 January 2016

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

scientific article published on 25 June 2004

Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors

scientific article published on May 2010

LINE-1 methylation in granulocyte DNA and trihalomethane exposure is associated with bladder cancer risk

scientific article

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

scientific article

Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.

scientific article

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

scientific article published on 02 March 2022

Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T Tumors.

scientific article

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

scientific article

No genome-wide DNA methylation changes found associated with medium-term reduced graphene oxide exposure in human lung epithelial cells

scientific article published on 18 September 2019

Promoter DNA hypermethylation and gene repression in undifferentiated Arabidopsis cells

scientific article

Release of Hypoacetylated and Trimethylated Histone H4 Is an Epigenetic Marker of Early Apoptosis

scientific article published in Journal of Biological Chemistry

Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas

scientific article

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

scientific article

The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion.

scientific article published on 15 January 2013

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA.

scientific article published on 06 March 2009

The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

scientific article published in 2023

The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.

scientific article published on 21 April 2007

The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

scientific article published in March 2003

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

scientific article published on 10 February 2009

The impact of MECP2 mutations in the expression patterns of Rett syndrome patients.

scientific article published on 11 November 2004

Paulina is supported by:

About Paulina

Help