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List of works by Richard Koche

2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation

scientific article published on 10 June 2019

A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1

scientific article published on 08 May 2019

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

scientific article published in February 2018

A gene–environment-induced epigenetic program initiates tumorigenesis

scientific article published on 03 February 2021

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer

scientific article published on 13 January 2020

Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance

scientific article published on 3 November 2017

Arid1a restrains Kras-dependent changes in acinar cell identity.

scientific article published on 17 July 2018

Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

scientific article published on 05 September 2019

DICER1 Is Essential for Self-Renewal of Human Embryonic Stem Cells

scientific article published on 23 August 2018

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

scientific article

Developmental chromatin programs determine oncogenic competence in melanoma

scientific article published in 2021

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.

scientific article published in December 2017

Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma

scientific article published on 16 November 2020

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

scientific article published on 11 May 2023

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma

scientific article published on 16 December 2019

FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST).

scientific article published on 21 November 2017

Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation

scientific article published on 20 May 2019

HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

scientific article published on 27 September 2018

Inhibition of MEK and ATR is effective in a B-cell acute lymphoblastic leukemia model driven by and activated

scientific article published on 01 October 2018

L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer

scientific article published on 13 January 2020

PGBD5 promotes site-specific oncogenic mutations in human tumors

scientific article published on 15 May 2017

PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression

article

Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer

scientific article published in 2024

Peptidomimetic blockade of MYB in acute myeloid leukemia

scientific article published on 9 January 2018

Publisher Correction: Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma

scientific article published on 01 April 2020

Reprogramming Factor Expression Initiates Widespread Targeted Chromatin Remodeling ⬇️

scientific article published on January 7, 2011

SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia.

scientific article

Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition

scientific article

Targeting the CALR interactome in myeloproliferative neoplasms

scientific article published on 15 November 2018

α-Ketoglutarate links p53 to cell fate during tumour suppression

scientific article published on 18 September 2019

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