List of works - Leigh Anne Eller

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

scientific article

Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors

scientific article published on 20 May 2021

B Cell Depletion in HIV-1 Subtype A Infected Ugandan Adults: Relationship to CD4 T Cell Count, Viral Load and Humoral Immune Responses ⬇️

scientific article published on August 23, 2011

Biomarkers of Inflammation Correlate With Clinical Scoring Indices in Human Immunodeficiency Virus-Infected Kenyans

scientific article published on 01 January 2019

Chikungunya and O'nyong-nyong Viruses in Uganda: Implications for Diagnostics

scientific article published on 03 January 2019

Combining Viral Genetics and Statistical Modeling to Improve HIV-1 Time-of-infection Estimation towards Enhanced Vaccine Efficacy Assessment

scientific article published on 03 July 2019

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 14 September 2017

Correlation of immunogenicities and in vitro expression levels of recombinant modified vaccinia virus Ankara HIV vaccines

scientific article

Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines

scientific article published on 03 August 2009

Differential loss of invariant natural killer T cells and FoxP3⁺ regulatory T cells in HIV-1 subtype A and subtype D infections

scientific article published on July 2013

Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir size

scientific article

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

scientific article published on 14 January 2020

Effect of human immunodeficiency virus Type 1 (HIV-1) subtype on disease progression in persons from Rakai, Uganda, with incident HIV-1 infection

scientific article published on March 2008

Elevated natural killer cell activity despite altered functional and phenotypic profile in Ugandans with HIV-1 clade A or clade D infection

scientific article published on August 2009

Evolution of HIV-1 within untreated individuals and at the population scale in Uganda

article

Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection

scientific article published on 3 February 2016

Expansion of Stem Cell-Like CD4+ Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease Progression

scientific article published on 28 June 2019

Factors influencing estimates of HIV-1 infection timing using BEAST

scientific article published on 01 February 2021

Global variability of the human IgG glycome ⬇️

scientific article published on 12 August 2020

HIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels

scientific article published on 17 November 2014

HIV prevalence and risk behavior among male and female adults screened for enrolment into a vaccine preparedness study in Maputo, Mozambique

scientific article published on 17 September 2019

HIV virologic failure and its predictors among HIV-infected adults on antiretroviral therapy in the African Cohort Study

scientific article published in PLoS ONE

HIV-1 viral subtype differences in the rate of CD4+ T-cell decline among HIV seroincident antiretroviral naive persons in Rakai district, Uganda

scientific article

High-throughput high-resolution class I HLA genotyping in East Africa

scientific article

Higher HIV-1 incidence and genetic complexity along main roads in Rakai District, Uganda

scientific article published on December 2006

Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge

scholarly article

Human immunodeficiency virus type 1 infection is associated with increased NK cell polyfunctionality and higher levels of KIR3DL1+ NK cells in ugandans carrying the HLA-B Bw4 motif

scientific article

Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort.

scientific article published on 19 April 2019

Identification of Acute HIV-1 Infection by Hologic Aptima HIV-1 RNA Qualitative Assay

scientific article

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

scientific article published on March 2004

Impact of early ART initiation on performance of cross sectional incidence assays

scientific article published on 16 April 2020

Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge

scientific article published on 9 January 2012

Induction of HIV-specific functional immune responses by a multiclade HIV-1 DNA vaccine candidate in healthy Ugandans

scientific article published on 17 September 2007

Innate and adaptive immune responses both contribute to pathological CD4 T cell activation in HIV-1 infected Ugandans

scientific article

Large-scale human immunodeficiency virus rapid test evaluation in a low-prevalence ugandan blood bank population

scientific article

Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization Breadth

scientific article published on 10 August 2021

Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study

scientific article

Markers of Cirrhosis and Inflammation in HIV/HBV Co-infection in a Ugandan Cohort

article

Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand

scientific article published on 06 February 2020

Monocyte activation, HIV, and cognitive performance in East Africa

scientific article published on 29 August 2019

Nautilus: A Bioinformatics Package for the Analysis of HIV Type 1 Targeted Deep Sequencing Data ⬇️

scientific article published on August 2, 2013

Novel application of Locked Nucleic Acid chemistry for a Taqman assay for measuring diverse human immunodeficiency virus type 1 subtypes ⬇️

scientific article published on September 21, 2010

Prospective Study of Acute HIV-1 Infection in Adults in East Africa and Thailand

scientific article

Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys ⬇️

scientific article published on 24 October 2013

Quality monitoring of HIV-1-infected and uninfected peripheral blood mononuclear cell samples in a resource-limited setting

scientific article

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 31 July 2017

Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate

scientific article

Reference intervals in healthy adult Ugandan blood donors and their impact on conducting international vaccine trials

scientific article

Relatively low HIV infection rates in rural Uganda, but with high potential for a rise: a cohort study in Kayunga District, Uganda

scientific article

Safety and Immunogenicity of PENNVAX®-G DNA Prime Administered by Biojector® 2000 or CELLECTRA® Electroporation Device with Modified Vaccinia Ankara-CMDR Boost

scientific article published on 2 September 2017

Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial

scientific article

Sex and Urbanicity Contribute to Variation in Lymphocyte Distribution across Ugandan Populations

scientific article published on 5 January 2016

Short Communication: Colony-Forming Hematopoietic Progenitor Cells Are Not Preferentially Infected by HIV Type 1 Subtypes A and Din Vivo ⬇️

scientific article published on February 2, 2012

Single-cell level response of HIV-specific and cytomegalovirus-specific CD4 T cells correlate with viral control in chronic HIV-1 subtype A infection

scientific article published in September 2012

Targeted deep sequencing of HIV-1 using the IonTorrentPGM platform

scientific article

Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection

scientific article

Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity

scientific article published on 13 September 2019

Viral kinetics in untreated versus treated acute HIV infection in prospective cohort studies in Thailand

scientific article

List of works by Leigh Anne Eller

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors

B Cell Depletion in HIV-1 Subtype A Infected Ugandan Adults: Relationship to CD4 T Cell Count, Viral Load and Humoral Immune Responses ⬇️

Biomarkers of Inflammation Correlate With Clinical Scoring Indices in Human Immunodeficiency Virus-Infected Kenyans

Chikungunya and O'nyong-nyong Viruses in Uganda: Implications for Diagnostics

Combining Viral Genetics and Statistical Modeling to Improve HIV-1 Time-of-infection Estimation towards Enhanced Vaccine Efficacy Assessment

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

Correlation of immunogenicities and in vitro expression levels of recombinant modified vaccinia virus Ankara HIV vaccines

Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines

Differential loss of invariant natural killer T cells and FoxP3⁺ regulatory T cells in HIV-1 subtype A and subtype D infections

Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir size

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

Effect of human immunodeficiency virus Type 1 (HIV-1) subtype on disease progression in persons from Rakai, Uganda, with incident HIV-1 infection

Elevated natural killer cell activity despite altered functional and phenotypic profile in Ugandans with HIV-1 clade A or clade D infection

Evolution of HIV-1 within untreated individuals and at the population scale in Uganda

Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection

Expansion of Stem Cell-Like CD4+ Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease Progression

Factors influencing estimates of HIV-1 infection timing using BEAST

Global variability of the human IgG glycome ⬇️

HIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels

HIV prevalence and risk behavior among male and female adults screened for enrolment into a vaccine preparedness study in Maputo, Mozambique

HIV virologic failure and its predictors among HIV-infected adults on antiretroviral therapy in the African Cohort Study

HIV-1 viral subtype differences in the rate of CD4+ T-cell decline among HIV seroincident antiretroviral naive persons in Rakai district, Uganda

High-throughput high-resolution class I HLA genotyping in East Africa

Higher HIV-1 incidence and genetic complexity along main roads in Rakai District, Uganda

Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge

Human immunodeficiency virus type 1 infection is associated with increased NK cell polyfunctionality and higher levels of KIR3DL1+ NK cells in ugandans carrying the HLA-B Bw4 motif

Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort.

Identification of Acute HIV-1 Infection by Hologic Aptima HIV-1 RNA Qualitative Assay

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

Impact of early ART initiation on performance of cross sectional incidence assays

Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge

Induction of HIV-specific functional immune responses by a multiclade HIV-1 DNA vaccine candidate in healthy Ugandans

Innate and adaptive immune responses both contribute to pathological CD4 T cell activation in HIV-1 infected Ugandans

Large-scale human immunodeficiency virus rapid test evaluation in a low-prevalence ugandan blood bank population

Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization Breadth

Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study

Markers of Cirrhosis and Inflammation in HIV/HBV Co-infection in a Ugandan Cohort

Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand

Monocyte activation, HIV, and cognitive performance in East Africa

Nautilus: A Bioinformatics Package for the Analysis of HIV Type 1 Targeted Deep Sequencing Data ⬇️

Novel application of Locked Nucleic Acid chemistry for a Taqman assay for measuring diverse human immunodeficiency virus type 1 subtypes ⬇️

Prospective Study of Acute HIV-1 Infection in Adults in East Africa and Thailand

Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys ⬇️

Quality monitoring of HIV-1-infected and uninfected peripheral blood mononuclear cell samples in a resource-limited setting

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate

Reference intervals in healthy adult Ugandan blood donors and their impact on conducting international vaccine trials

Relatively low HIV infection rates in rural Uganda, but with high potential for a rise: a cohort study in Kayunga District, Uganda

Safety and Immunogenicity of PENNVAX®-G DNA Prime Administered by Biojector® 2000 or CELLECTRA® Electroporation Device with Modified Vaccinia Ankara-CMDR Boost

Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial

Sex and Urbanicity Contribute to Variation in Lymphocyte Distribution across Ugandan Populations

Short Communication: Colony-Forming Hematopoietic Progenitor Cells Are Not Preferentially Infected by HIV Type 1 Subtypes A and Din Vivo ⬇️

Single-cell level response of HIV-specific and cytomegalovirus-specific CD4 T cells correlate with viral control in chronic HIV-1 subtype A infection

Targeted deep sequencing of HIV-1 using the IonTorrentPGM platform

Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection

Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity

Viral kinetics in untreated versus treated acute HIV infection in prospective cohort studies in Thailand