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List of works by Thomas W. Chittenden

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells

scientific article published on 01 April 2018

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

scientific article

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

scientific article published on October 1999

A novel anti-CD37 antibody-drug conjugate with multiple anti-tumor mechanisms for the treatment of B-cell malignancies

scientific article published on 3 September 2013

Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

scientific article published on 14 February 2018

Aging and neurodegeneration are associated with increased mutations in single human neurons.

scientific article published on 7 December 2017

An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation

scientific article published in August 2003

Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen

scientific article

Automated migration analysis based on cell texture: method & reliability

scientific article

BH3 domains: intracellular death-ligands critical for initiating apoptosis

scientific article

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases

scientific article published on 01 May 1999

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

scientific article

Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins

scientific article

Cell types differ in global coordination of splicing and proportion of highly expressed genes

scientific article published on 31 August 2016

Characterization of synectin expression and promoter activity

scientific article

Chronic mTOR activation induces a degradative smooth muscle cell phenotype

scientific article published on 01 March 2020

Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium

scientific article published on 13 June 2019

Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis

scientific article published on 26 August 2019

Enhancing Retrosynthetic Reaction Prediction with Deep Learning Using Multiscale Reaction Classification

scientific article published on 01 February 2019

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

scientific article

FGF-dependent metabolic control of vascular development

scientific article published on 3 May 2017

Functional classification analysis of somatically mutated genes in human breast and colorectal cancers

scientific article published on 22 April 2008

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

scientific article

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

scientific article

IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors

scientific article published on 22 April 2015

In silico phenotype projection of endothelial ERK1/2 signaling

scientific article published on 12 June 2020

Induction of apoptosis by the Bcl-2 homologue Bak

scientific article

Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment

scientific article published on 01 July 2018

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

scientific article

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways ⬇️

scientific article (publication date: October 2003)

Resilience, disease and the age of single cell science

scientific article published on 10 February 2020

SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies

scientific article

Science and technology consortia in U.S. biomedical research: A paradigm shift in response to unsustainable academic growth

scientific article published on 12 November 2014

Selective regulation of arterial branching morphogenesis by synectin

scientific article published in June 2006

Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

scientific article published on 15 December 2017

Smooth Muscle Cell Reprogramming in Aortic Aneurysms

scientific article published on 01 April 2020

Somatic mutation in single human neurons tracks developmental and transcriptional history

scientific article

Synectin-dependent gene expression in endothelial cells.

scientific article published on 29 August 2006

Synectin/syndecan-4 regulate coronary arteriolar growth during development

scientific article published in July 2007

Therapeutic implications of GIPC1 silencing in cancer

scientific article

Transcriptional Profiling in Coronary Artery Disease

scholarly article by Thomas W. Chittenden et al published 24 October 2006 in Circulation

Unique cardiopulmonary exercise test responses in overweight middle-aged adults with obstructive sleep apnea

scientific article published in February 2007

ei24, a p53 response gene involved in growth suppression and apoptosis

scientific article

nEASE: a method for gene ontology subclassification of high-throughput gene expression data.

scientific article

p53 has a direct apoptogenic role at the mitochondria

scientific article

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