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List of works by Edward D Levin

Acute and chronic interactive treatments of serotonin 5HT2C and dopamine D1 receptor systems for decreasing nicotine self-administration in female rats

scientific article published on 27 August 2019

Acute oral 18-methoxycoronaridine (18-MC) decreases both alcohol intake and IV nicotine self-administration in rats.

scientific article published on 29 October 2016

Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature

scientific article published in August 2004

Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates

scientific article

Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models

scientific article

Adolescent-onset nicotine self-administration modeled in female rats

scientific article published on 23 May 2003

Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish

scientific article published on 03 January 2020

Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors

scientific article published on 17 April 2015

Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats

scientific article published on 19 June 2015

Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats

scientific article published on 03 March 2020

Anxiolytic effects of nicotine in zebrafish

scientific article published on 13 October 2006

Are adolescents more vulnerable to drug addiction than adults? Evidence from animal models

scientific article

Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats ⬇️

scientific article published on July 1, 2012

Assessment of pregnenolone effects on alcohol intake and preference in male alcohol preferring (P) rats

scientific article published on 10 July 2014

Attention-modulating effects of cognitive enhancers ⬇️

scientific article published on February 18, 2011

Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats

scientific article published on 17 November 2008

Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation

scientific article published in January 2004

Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease

scientific article published on 28 February 2020

Branched-chain amino acids alter neurobehavioral function in rats

scientific article published on 18 December 2012

Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes

scientific article published on 7 August 2012

Bupropion-varenicline interactions and nicotine self-administration behavior in rats

scientific article

Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety

scientific article published on 28 July 2009

Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats.

scientific article published on 30 April 2009

Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats

scientific article published on April 2013

Chlorpyrifos exposure of developing zebrafish: effects on survival and long-term effects on response latency and spatial discrimination

scientific article published in January 2003

Chronic memantine decreases nicotine self-administration in rats

scientific article published on 14 August 2019

Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats

scientific article

Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding

scientific article published in April 2005

Chronic nicotine interactions with clozapine and risperidone and attentional function in rats

scientific article published on 28 November 2005

Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.

scientific article

Chronic underactivity of medial frontal cortical beta2-containing nicotinic receptors increases clozapine-induced working memory impairment in female rats

scientific article published on 24 December 2008

Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response

scientific article

Cognitive and Behavioral Impairments Evoked by Low-Level Exposure to Tobacco Smoke Components: Comparison with Nicotine Alone

scientific article published on 26 February 2016

Combined Agonist-Antagonist Treatment for Nicotine and Other Drug Dependencies

Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity

scientific article

Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions

scientific article published on 03 February 2009

Corrigendum to "The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]pyrene: Effects on Cholinergic and Serotonergic Systems"

scientific article published on 01 March 2019

Critical developmental periods for effects of low-level tobacco smoke exposure on behavioral performance

scientific article published on 20 July 2018

Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity.

scientific article published on 2 July 2011

D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response ⬇️

scientific article published on December 28, 2010

Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands.

scientific article

Developmental Exposure to Low Concentrations of Organophosphate Flame Retardants Causes Life-Long Behavioral Alterations in Zebrafish

scientific article published on 01 October 2018

Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine

scientific article

Developmental chlorpyrifos effects on hatchling zebrafish swimming behavior

scientific article published in November 2004

Developmental diazinon neurotoxicity in rats: later effects on emotional response

scientific article

Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression

scientific article

Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function

scientific article published on 27 May 2020

Developmental exposure to an organophosphate flame retardant alters later behavioral responses to dopamine antagonism in zebrafish larvae

scientific article published on 17 March 2018

Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish

scientific article

Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood

scientific article published on 12 November 2007

Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood

scientific article

Dextromethorphan and bupropion reduces high level remifentanil self-administration in rats

scientific article published on 01 April 2020

Dextromethorphan interactions with histaminergic and serotonergic treatments to reduce nicotine self-administration in rats

scientific article published on 15 December 2015

Different Lines of Rats Selectively-Bred for High Alcohol-Drinking Demonstrate Disparate Preferences for Nicotine Self-Administration

scientific article published in 2016

Differential acetylcholinesterase inhibition of chlorpyrifos, diazinon and parathion in larval zebrafish ⬇️

scientific article published on October 19, 2011

Differential effects of non-nicotine tobacco constituent compounds on nicotine self-administration in rats

scientific article published on 21 February 2014

Differential effects of the antidepressant mirtazapine on amphetamine- and dizocilpine-induced PPI deficits ⬇️

scientific article published on March 25, 2012

Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats.

scientific article

Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes

scientific article published on 2 November 2016

Dopamine D1 and D2 receptor antagonism during development alters later behavior in zebrafish

scientific article published on 30 August 2018

Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging

scientific article

Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats

scientific article

Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats ⬇️

scientific article published on April 20, 2012

Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats

scientific article published on 01 January 2007

Effects of caffeine on alcohol consumption and nicotine self-administration in rats

scientific article published on 23 April 2013

Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats ⬇️

scientific article published on October 26, 2012

Effects of ethanol, Δ9-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats ⬇️

scientific article published on August 29, 2012

Effects of nicotine and mecamylamine on choice accuracy in an operant visual signal detection task in female rats

scientific article published on 20 September 2002

Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats

scientific article published on 10 June 2010

Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats ⬇️

scientific article published on February 24, 2012

Effects of sub-chronic methylphenidate on risk-taking and sociability in zebrafish (Danio rerio)

scientific article published on 06 February 2020

Effects of the sazetidine-a family of compounds on the body temperature in wildtype, nicotinic receptor β2-/- and α7-/- mice.

scientific article published on 12 September 2013

Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats

scientific article

Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene

scientific article

Evaluation of the Association between Maternal Smoking, Childhood Obesity, and Metabolic Disorders: A National Toxicology Program Workshop Review ⬇️

scientific article published on December 11, 2012

Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood

scientific article

Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood

scientific article

Exposure to 1,2-Propanediol Impacts Early Development of Zebrafish (Danio rerio) and Induces Hyperactivity

scientific article

Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development

scientific article published on 22 June 2016

From molecular mechanisms to functional impact: Developing integrated analyses in neurotoxicology - The 16 biennial meeting International Neurotoxicology Association and 8 meeting of the NeuroToxicity Society

article

Gene-environment interactions: neurodegeneration in non-mammals and mammals

scientific article (publication date: September 2010)

Genetic aspects of behavioral neurotoxicology

scientific article

Gestational and perinatal exposure to diazinon causes long-lasting neurobehavioral consequences in the rat

scientific article published on 05 November 2019

Gestational dexamethasone treatment elicits sex-dependent alterations in locomotor activity, reward-based memory and hippocampal cholinergic function in adolescent and adult rats

scientific article published in September 2005

Gestational exposure to nicotine and/or benzo[a]pyrene causes long-lasting neurobehavioral consequences

scientific article published on 31 July 2019

Guidelines on nicotine dose selection for in vivo research.

scientific article published on 9 August 2006

Heterogeneity across brain regions and neurotransmitter interactions with nicotinic effects on memory function

scientific article published on January 2015

Heterogeneity of toxicant response: sources of human variability

scientific article

Histamine H1 antagonist treatment with pyrilamine reduces nicotine self-administration in rats ⬇️

scientific article published on October 15, 2010

Histamine H1 receptor involvement in prepulse inhibition and memory function: relevance for the antipsychotic actions of clozapine

scientific article

Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine

scientific article published on 27 March 2008

Improvement of attentional function with antagonism of nicotinic receptors in female rats ⬇️

scientific article published on February 8, 2013

Increased nicotine self-administration following prenatal exposure in female rats

scientific article published on November 2006

Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task

scientific article

Is There a Critical Period for the Developmental Neurotoxicity of Low-Level Tobacco Smoke Exposure?

scientific article

JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.

scientific article published on 18 November 2010

Ketamine Differentially Attenuates Alcohol Intake in Male Versus Female Alcohol Preferring (P) Rats

scientific article published on 28 July 2017

Ketanserin, a 5-HT2 receptor antagonist, decreases nicotine self-administration in rats

scientific article published on 17 October 2008

Learning impairment caused by a toxin produced by Pfiesteria piscicida infused into the hippocampus of rats

scientific article published in July 2003

Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice.

scientific article published on 18 March 2008

Long-term effects of chronic intermittent ethanol exposure in adolescent and adult rats: radial-arm maze performance and operant food reinforced responding

scientific article published on 13 May 2013

Lorcaserin, a 5-HT2C Agonist, Decreases Nicotine Self-Administration in Female Rats ⬇️

scientific article published on June 2, 2011

Lorcaserin, a selective 5-HT(2C) receptor agonist, decreases alcohol intake in female alcohol preferring rats

scientific article published on 7 August 2014

Maternal transfer of nanoplastics to offspring in zebrafish (Danio rerio): A case study with nanopolystyrene

scientific article published on 22 June 2018

Meclizine enhancement of sensorimotor gating in healthy male subjects with high startle responses and low prepulse inhibition

scientific article

Mercury-induced cognitive impairment in metallothionein-1/2 null mice

scientific article published on 15 December 2007

Metallothionein expression and neurocognitive function in mice

scientific article published on 23 January 2006

Metallothionein in the central nervous system: Roles in protection, regeneration and cognition

scientific article published on 19 January 2008

Mode of action: disruption of brain cell replication, second messenger, and neurotransmitter systems during development leading to cognitive dysfunction--developmental neurotoxicity of nicotine

scientific article

Mutually augmenting interactions of dextromethorphan and sazetidine-A for reducing nicotine self-administration in rats

scientific article

Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems

scientific article

Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits

scientific article

Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum

scientific article

Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood

scientific article

Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats

scientific article

Neurobehavioral effects of 1,2-propanediol in zebrafish (Danio rerio).

scientific article published on 9 February 2018

Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish

scientific article (publication date: 2015)

Nicotine and clozapine actions on pre-pulse inhibition deficits caused by N-methyl-D-aspartate (NMDA) glutamatergic receptor blockade

scientific article published in May 2005

Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats

scientific article published on 13 February 2007

Nicotine effects on learning in zebrafish: the role of dopaminergic systems

scientific article

Nicotine interactions with haloperidol, clozapine and risperidone and working memory function in rats

scientific article published in October 2002

Nicotine-alcohol interactions and attentional performance on an operant visual signal detection task in female rats

scientific article published in August 2003

Nicotine-alcohol interactions and cognitive function in rats

scientific article

Nicotine-antipsychotic drug interactions and attentional performance in female rats

scientific article published in February 2004

Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice

scientific article published on 11 September 2008

Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization

scientific article

Nicotinic involvement in memory function in zebrafish

scientific article published in November 2004

Nicotinic-glutamatergic interactions and attentional performance on an operant visual signal detection task in female rats

scientific article published in March 2003

Nicotinic-serotonergic drug interactions and attentional performance in rats

scientific article

Olanzapine interactions with nicotine and mecamylamine in rats: effects on memory function

scientific article published on 17 February 2005

Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats

scientific article

Oral sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, reduces nicotine self-administration in rats

scientific article published on 19 February 2019

Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition

scientific article

Outcomes of developmental exposure to total particulate matter from cigarette smoke in zebrafish (Danio rerio)

scientific article published on 17 July 2018

PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin ⬇️

scientific article published on September 2, 2010

Paternal THC exposure in rats causes long-lasting neurobehavioral effects in the offspring

scientific article published on 24 April 2019

Paternal factors in neurodevelopmental toxicology: THC exposure of male rats causes long-lasting neurobehavioral effects in their offspring

scientific article published on 08 February 2020

Paternal nicotine exposure in rats produces long-lasting neurobehavioral effects in the offspring

scientific article published on 16 May 2019

Paternal Δ9-Tetrahydrocannabinol Exposure Prior to Mating Elicits Deficits in Cholinergic Synaptic Function in the Offspring

scientific article published on 01 April 2020

Perinatal diazinon exposure compromises the development of acetylcholine and serotonin systems

scientific article published on 25 June 2019

Persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine D1 receptor antagonist SCH-23390 or the serotonin 5-HT2C agonist lorcaserin

scientific article published on 09 November 2018

Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion

scientific article

Persistent behavioral effects following early life exposure to retinoic acid or valproic acid in zebrafish

scientific article published on 3 October 2015

Persistent behavioral impairment caused by embryonic methylphenidate exposure in zebrafish ⬇️

scientific article published on July 7, 2011

Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon

scientific article

Persistent high alcohol consumption in alcohol-preferring (P) rats results from a lack of normal aversion to alcohol

scientific article published on 30 March 2010

Persistent neurobehavioral effects of early postnatal domoic acid exposure in rats

scientific article published on 24 August 2006

Persisting behavioral consequences of prenatal domoic acid exposure in rats

scientific article published on 27 July 2005

Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior

scientific article

Persisting neurobehavioral effects of developmental copper exposure in wildtype and metallothionein 1 and 2 knockout mice

scientific article

Pharmacological analyses of learning and memory in zebrafish (Danio rerio).

scientific article

Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations

scientific article published on November 2002

Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor

scientific article

Prenatal nicotine changes the response to postnatal chlorpyrifos: Interactions targeting serotonergic synaptic function and cognition

scientific article

Prolonging the Reduction of Nicotine Self-Administration in Rats by Coadministering Chronic Nicotine With Amitifadine, a Triple Monoamine Reuptake Inhibitor With CYP2B6 Inhibitory Actions

scientific article published on 01 February 2020

Reduction of nicotine self-administration by chronic nicotine infusion with H1 histamine blockade in female rats

scientific article published on 18 June 2016

Repeat exposure to ciguatoxin leads to enhanced and sustained thermoregulatory, pain threshold and motor activity responses in mice: relationship to blood ciguatoxin concentrations

scientific article

Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions

scientific article published in June 2005

Role of individual and developmental differences in voluntary cocaine intake in rats

scientific article

Role of insular cortex D₁ and D₂ dopamine receptors in nicotine self-administration in rats

scientific article published on 12 August 2013

Role of nicotinic receptors in the lateral habenula in the attenuation of amphetamine-induced prepulse inhibition deficits of the acoustic startle response in rats.

scientific article

Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats

scientific article published on 10 December 2009

Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague–Dawley rats ⬇️

scientific article published on January 28, 2011

Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes ⬇️

scientific article published on October 28, 2010

Sub-anesthetic doses of ketamine attenuate nicotine self-administration in rats

scientific article published on 12 January 2018

Teratogenic, bioenergetic, and behavioral effects of exposure to total particulate matter on early development of zebrafish (Danio rerio) are not mimicked by nicotine

scientific article published on 18 September 2015

The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]Pyrene: Effects on Cholinergic and Serotonergic Systems

scientific article published on 01 January 2019

The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety

scientific article

The use of zebrafish (Danio rerio) as a model system in neurobehavioral toxicology

scientific article published on 01 November 2004

The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats

scientific article published on 25 January 2017

The α2-adrenergic antagonist idazoxan counteracts prepulse inhibition deficits caused by amphetamine or dizocilpine in rats ⬇️

scientific article published on June 28, 2011

Threshold of adulthood for the onset of nicotine self-administration in male and female rats

scientific article

Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial

scientific article published on 15 September 2006

Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish (Danio rerio).

scientific article

Ventral hippocampal NMDA blockade and nicotinic effects on memory function

scientific article published in September 2003

WITHDRAWN: NBTS 2012 abstracts ⬇️

retracted scientific article published on 17 April 2012

Zebrafish Show Long-term Behavioral Impairments Resulting from Developmental Vitamin D Deficiency

scientific article published on 16 June 2020

Zebrafish model systems for developmental neurobehavioral toxicology

scientific article

Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits

scientific article

α4β2 Nicotinic receptor desensitizing compounds can decrease self-administration of cocaine and methamphetamine in rats

scientific article published on 07 December 2018

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