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List of works by Hassan Fahmi

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

scientific article published on 9 September 2008

ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis

scientific article

Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.

scientific article published on 15 March 2004

Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study

scientific article published on January 2007

Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype

scientific article published on 30 January 2013

Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal

scientific article published on January 2006

An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis

scientific article published on 26 April 2017

Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model

scientific article

Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo

scientific article

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

scientific article published on 20 March 2014

Cartilage-specific deletion of prar-gamma in mice results in early endochondral ossification defects and accelerated aging-dependent development of osteoarthritis

scientific article published on 9 February 2012

Cellular Aging, Senescence and Autophagy Processes in Osteoarthritis

scientific article published on 27 July 2015

Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study

scientific article

Contribution of H3K4 methylation by SET‐1A to interleukin‐1–induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes ⬇️

scientific article published on January 1, 2011

Corrigendum: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis

scientific article published in December 2017

Cyclooxygenase-2 and prostaglandins in articular tissues

scientific article published on December 2003

Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors

scientific article published on 26 April 2008

Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade

scientific article

Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes ⬇️

scientific article published on March 28, 2012

Egr-1 mediates the suppressive effect of IL-1 on PPARg expression in human OA chondrocytes

scientific article published on 9 February 2012

Egr-1 mediates the suppressive effect of IL-1 on PPARγ expression in human OA chondrocytes

scientific article published on 28 November 2012

Elucidating the Role of Protandim and 6-Gingerol in Protection Against Osteoarthritis

scientific article published on 27 July 2016

Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis.

scientific article

Empowering the immune fate of bone marrow mesenchymal stromal cells: gene and protein changes

scientific article published on 14 November 2018

Exacerbation of Aging-Associated and Instability-Induced Murine Osteoarthritis With Deletion of D Prostanoid Receptor 1, a Prostaglandin D2 Receptor

scientific article published on 23 May 2017

Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

scientific article published in May 2005

Expression of PPARα, β, and γ in the Hartley guinea pig model of primary osteoarthritis.

scientific article published on 28 November 2012

Expression of Peroxisome Proliferator-activated Receptors α, β, γ, and H- and L-Prostaglandin D Synthase During Osteoarthritis in the Spontaneous Hartley Guinea Pig and Experimental Dog Models ⬇️

scientific article published on April 1, 2013

Glucosamine Sulfate Reduces Prostaglandin E2Production in Osteoarthritic Chondrocytes Through Inhibition of Microsomal PGE Synthase-1 ⬇️

scientific article published on November 15, 2011

HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity

scientific article

High in vivo levels of adipsin lead to increased knee tissue degradation in osteoarthritis: data from humans and animal models

scientific article published on 01 October 2018

Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis

scientific article published on 18 March 2009

In vitro and in vivo assessment of the proresolutive and antiresorptive actions of resolvin D1: relevance to arthritis

In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.

scientific article

In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis ⬇️

scientific article published on 11 January 2018

In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice

scientific article published on 01 February 2020

Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage

scientific article published on 18 December 2008

Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes

scientific article published on 01 July 2012

Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism

scientific article published in January 2005

Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2.

scientific article published in November 2008

Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes

scientific article

Mesenchymal Stem/Stromal Cells in Immunity and Disease: A Better Understanding for an Improved Use

scientific article published on 18 May 2020

Mesenchymal Stromal Cell-Based Therapy: New Perspectives and Challenges.

scientific article published on 8 May 2019

NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis

scientific article

New evidence implicating 4-hydroxynonenal in the pathogenesis of osteoarthritis in vivo

scientific article published on 01 September 2014

New insights into prostaglandin biology

scientific article published on 01 January 2004

New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets

scientific article

Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism

scientific article

Nuclear receptor retinoid-related orphan receptor α1 modulates the metabolic activity of human osteoblasts ⬇️

scientific article published on August 1, 2011

PPARgamma ligands as modulators of inflammatory and catabolic responses in arthritis. An overview.

scientific article

PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage

scientific article published on 8 January 2015

Peroxisome proliferator-activated receptor gamma in osteoarthritis ⬇️

scientific article published on 04 September 2010

Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes

scientific article published on January 2007

Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis

scientific article published on 26 October 2010

Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis ⬇️

scientific article published on October 18, 2012

Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes

scientific article

Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids

scientific article published in December 2004

Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' - authors' reply ⬇️

scientific article published on April 3, 2013

Role of Lipocalin-type prostaglandin D synthase in experimental osteoarthritis

scientific article published on 26 April 2020

Role of TL1A in the pathogenesis of rheumatoid arthritis

scientific article published on 28 September 2009

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis ⬇️

scientific article published on November 30, 2010

Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes

scientific article published on 25 May 2014

Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium

scientific article published on 13 October 2012

Systematic review of the association between chronic social stress and telomere length: A life course perspective.

scientific article

The Impact of Cell-Expansion and Inflammation on The Immune-Biology of Human Adipose Tissue-Derived Mesenchymal Stromal Cells

scientific article published on 04 March 2020

The Therapeutic Potential of Mesenchymal Stromal Cells for Regenerative Medicine: Current Knowledge and Future Understandings ⬇️

journal article from 'Frontiers in Cell and Developmental Biology' published in 2021

The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice.

scientific article published on 29 November 2014

The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and ca

scientific article published on 01 July 2007

The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis.

scientific article

The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target

scientific article published on 19 July 2016

Therapeutic Mesenchymal Stem/Stromal Cells: Value, Challenges and Optimization

scientific article

Valproic acid suppresses interleukin-1ß-induced microsomal prostaglandin E2 synthase-1 expression in chondrocytes through upregulation of NAB1

scientific article published on 15 January 2011

mPGES-1 as a novel target for arthritis

scientific article published in September 2004

mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis ⬇️

scientific article published on January 25, 2011

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