Search filters

List of works by Emiel F M Wouters

A Call for High-Quality Advance Care Planning in Outpatients With Severe COPD or Chronic Heart Failure

scientific article published on 09 September 2010

A Comparative Study of Lung Host Defense in Murine Obesity Models. Insights into Neutrophil Function

scientific article

A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.

scientific article

A dosage of opioids should never exceed what is necessary to relieve symptoms

scientific article published on 01 December 2008

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.

scientific article published on 11 November 2011

A new perspective on COPD exacerbations: monitoring impact by measuring physical, psychological and social resilience

scientific article published in April 2016

A patient-centred interdisciplinary palliative care programme for end-stage chronic respiratory diseases

scientific article published on 01 April 2010

A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. A retrospective 18F-FDG-PET/CT pilot study

scientific article published on 13 April 2014

A qualitative assessment of COPD patients' experiences of pulmonary rehabilitation and guidance by healthcare professionals.

scientific article published on 13 November 2013

A randomised controlled trial on the efficacy of advance care planning on the quality of end-of-life care and communication in patients with COPD: the research protocol

scientific article published on 02 January 2014

A randomized clinical trial investigating the efficacy of targeted nutrition as adjunct to exercise training in COPD.

scientific article published on 12 June 2017

A role for anabolic steroids in the rehabilitation of patients with COPD? A double-blind, placebo-controlled, randomized trial

scientific article published in November 2003

A systems medicine clinical platform for understanding and managing non- communicable diseases.

scientific article published on January 2014

Abdominal fat mass contributes to the systemic inflammation in chronic obstructive pulmonary disease

scientific article published on 02 June 2010

Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice

scientific article published on April 2016

Ablation of the Thiol Transferase Glutaredoxin-1 Augments Protein S-Glutathionylation and Modulates Type 2 Inflammatory Responses and IL-17 in a House Dust Mite Model of Allergic Airway Disease in Mice

scientific article published on March 2016

Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling

scientific article

Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease

scientific article published on 29 June 2016

Age-graded reductions in quadriceps muscle strength and peak aerobic capacity in COPD

scientific article published on 01 March 2012

Aggravation of Allergic Airway Inflammation by Cigarette Smoke in Mice Is CD44-Dependent

scientific article

Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease

scientific article published on 19 June 2008

Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells

scientific article published on 16 April 2016

Altered antioxidant status in peripheral skeletal muscle of patients with COPD.

scientific article published in January 2005

Altered cigarette smoke-induced lung inflammation due to ablation of Grx1

scientific article

Altered interorgan response to feeding in patients with chronic obstructive pulmonary disease

scientific article

American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation

scientific article

An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabilitation

scientific article published on 01 October 2013

An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease

scientific article published on April 2015

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.

scientific article published on April 2015

An official European Respiratory Society statement on physical activity in COPD.

scientific article published on 30 October 2014

Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity

scientific article published on 12 January 2017

Anemia is Associated with Bone Mineral Density in Chronic Obstructive Pulmonary Disease

scientific article published on December 28, 2012

Antagonistic implications of sarcopenia and abdominal obesity on physical performance in COPD.

scientific article published on 16 April 2015

Arm mechanical efficiency and arm exercise capacity are relatively preserved in chronic obstructive pulmonary disease

scientific article published on October 2002

Arterial stiffness in patients with COPD: the role of systemic inflammation and the effects of pulmonary rehabilitation.

scientific article

Association of glutathione-S-transferase omega haplotypes with susceptibility to chronic obstructive pulmonary disease.

scientific article

Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD.

scientific article published on 25 February 2014

Associations between COPD related manifestations: a cross-sectional study

scientific article

Bacterial infections in patients requiring admission for an acute exacerbation of COPD; a 1-year prospective study

scientific article published on July 2003

Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial

scientific article published on 7 April 2016

Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.

scientific article

Bone attenuation on routine chest CT correlates with bone mineral density on DXA in patients with COPD.

scientific article published in November 2012

Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease

article

Burden of COPD in patients treated in different care settings in the Netherlands

scientific article

COPD as a lung disease with systemic consequences--clinical impact, mechanisms, and potential for early intervention

scientific article published on August 2008

COPD health-care delivery: a holistic and dynamic approach is needed

scientific article published on 01 June 2016

COPD management: need for more consensus

scientific article

COPD: the patient perspective

scientific article

COgnitive-pulmonary disease

scientific article published on 16 March 2014

CT-measured bone attenuation in patients with chronic obstructive pulmonary disease: Relation to clinical features and outcomes

scientific article published on June 1, 2013

Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations

scientific article published on 25 July 2006

Care dependency independently predicts two-year survival in outpatients with advanced chronic organ failure

scientific article published on 07 November 2012

Casein protein results in higher prandial and exercise induced whole body protein anabolism than whey protein in chronic obstructive pulmonary disease

scientific article

Catalase overexpression fails to attenuate allergic airways disease in the mouse

scientific article

Cellular protein breakdown and systemic inflammation are unaffected by pulmonary rehabilitation in COPD.

scientific article

Changes in Forced Expiratory Volume in 1 Second over Time in COPD

scientific article published on September 26, 2011

Changes in physical activity and all-cause mortality in COPD.

scientific article published on 25 July 2014

Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD.

scientific article published on 31 March 2017

Characterisation of COPD heterogeneity in the ECLIPSE cohort

scientific article published on September 10, 2010

Characteristics and determinants of endurance cycle ergometry and six-minute walk distance in patients with COPD.

scientific article

Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort

scientific article

Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers

scientific article

Chronic obstructive pulmonary disease

scientific article published on 03 December 2015

Chronic obstructive pulmonary disease phenotypes: the future of COPD.

scientific article published on 3 June 2010

Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants

scientific article published on 27 March 2017

Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition.

scientific article

Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death.

scientific article published on 31 March 2011

Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD.

scientific article published on 23 March 2016

Clinical and prognostic heterogeneity of C and D GOLD groups

scientific article published in July 2015

Clusters of Comorbidities Based on Validated Objective Measurements and Systemic Inflammation in Patients with Chronic Obstructive Pulmonary Disease

scientific article published on April 1, 2013

Cognitive functioning in obstructive lung disease: results from the United Kingdom biobank

scientific article published in March 2014

Cognitive impairment and clinical characteristics in patients with chronic obstructive pulmonary disease.

scientific article

Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease

scientific article

Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort

scientific article published on June 19, 2013

Comprehensive Lung Function Assessment Does not Allow to Infer Response to Pulmonary Rehabilitation in Patients with COPD

Contribution of individual COPD assessment test (CAT) items to CAT total score and effects of pulmonary rehabilitation on CAT scores

scientific article published on 30 October 2018

Coping styles in patients with COPD before and after pulmonary rehabilitation

scientific article published on March 29, 2013

Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality

scientific article published on 28 January 2014

Correlates of osteoporosis in chronic obstructive pulmonary disease: An underestimated systemic component

scientific article published on 01 August 2009

Correlations between disease-specific and generic health status questionnaires in patients with advanced COPD: a one-year observational study

scientific article

Critical view on diagnosing muscle wasting by single-frequency bio-electrical impedance in COPD.

scientific article published on 30 July 2009

Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells

scientific article published on 16 April 2018

De novo glutamine synthesis induced by corticosteroids in vivo in rats is secondary to weight loss

scientific article published in October 2004

Decreased plasma sRAGE levels in COPD: influence of oxygen therapy

scientific article published on 31 January 2012

Decreased whole-body and splanchnic glutamate metabolism in healthy elderly men and patients with chronic obstructive pulmonary disease in the postabsorptive state and in response to feeding

scientific article published in September 2005

Definitions of exacerbations: does it really matter in clinical trials on COPD?

scientific article published on September 2009

Determinants of 1-year changes in disease-specific health status in patients with advanced chronic obstructive pulmonary disease: A 1-year observational study

scientific article

Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort

scientific article published in October 2010

Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study

scientific article

Determinants of functional, peak and endurance exercise capacity in people with chronic obstructive pulmonary disease

scientific article published on 29 March 2018

Determinants of polypharmacy and compliance with GOLD guidelines in patients with chronic obstructive pulmonary disease

scientific article published on 26 September 2011

Diet and vitamin D as risk factors for lung impairment and COPD

scientific article published on May 17, 2013

Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells

scientific article published in October 2007

Differences in content and organisational aspects of pulmonary rehabilitation programmes.

scientific article published on 12 December 2013

Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

scientific article

Differences in walking pattern during 6-min walk test between patients with COPD and healthy subjects

scientific article

Differential response to pulmonary rehabilitation in COPD: multidimensional profiling

scientific article

Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging.

scientific article published on 14 April 2019

Dynamic Preferences for Site of Death Among Patients With Advanced Chronic Obstructive Pulmonary Disease, Chronic Heart Failure, or Chronic Renal Failure

scientific article published on April 6, 2013

Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

scientific article

Dysregulated adipokine metabolism in chronic obstructive pulmonary disease

scientific article published on June 15, 2012

Early body weight loss during concurrent chemo-radiotherapy for non-small cell lung cancer

scientific article

Echocardiographic abnormalities and their impact on health status in patients with COPD referred for pulmonary rehabilitation

scientific article published on 21 December 2016

Effect of glutamate ingestion on whole-body glutamate turnover in healthy elderly and patients with chronic obstructive pulmonary disease

scientific article published on 13 March 2006

Effect of infliximab on local and systemic inflammation in chronic obstructive pulmonary disease: a pilot study

scientific article published on 15 February 2008

Effect of ‘activity monitor-based’ counseling on physical activity and health-related outcomes in patients with chronic diseases: A systematic review and meta-analysis

scientific article published on 03 July 2013

Effects of body mass index on task-related oxygen uptake and dyspnea during activities of daily life in COPD

scientific article

Effects of neuromuscular electrical stimulation of muscles of ambulation in patients with chronic heart failure or COPD: a systematic review of the English-language literature

scientific article published on 10 April 2009

Effects of obesity on weight-bearing versus weight-supported exercise testing in patients with COPD.

scientific article published on 9 December 2015

Effects of whole-body exercise training on body composition and functional capacity in normal-weight patients with COPD.

scientific article published in June 2004

Efficacy of advance care planning: a systematic review and meta-analysis

scientific article published on 02 March 2014

Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: response from the authors

scientific article published on 13 June 2014

Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: results from the DICES trial

scientific article published on 07 January 2014

Efficacy of nutritional supplementation therapy in depleted patients with chronic obstructive pulmonary disease

scientific article published in February 2003

Efficacy of walking aids on self-paced outdoor walking in individuals with COPD: A randomized cross-over trial

scientific article published on 5 July 2015

Emphysema and extrapulmonary tissue loss in COPD: a multi-organ loss of tissue phenotype

scientific article published on 7 February 2018

Energy balance in depleted ambulatory patients with chronic obstructive pulmonary disease: the effect of physical activity and oral nutritional supplementation

scientific article published on 01 May 2003

Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice

scientific article published on 12 August 2009

Enhanced myogenic differentiation by extracellular matrix is regulated at the early stages of myogenesis

scientific article published on March 1, 2003

Eosinophilia, Frequent Exacerbations, and Steroid Response in Chronic Obstructive Pulmonary Disease

scientific article

Erratum to: Impaired health status and care dependency in patients with advanced COPD or chronic heart failure

scientific article published on 3 April 2012

Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale

scientific article

Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study

scientific article published on 9 March 2006

Exercise training restores uncoupling protein-3 content in limb muscles of patients with chronic obstructive pulmonary disease

scientific article

Exercise-induced oxygen desaturation in COPD patients without resting hypoxemia

scientific article published on 9 October 2013

Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease

scientific article published on 15 January 2016

Extra-pulmonary features in COPD patients entering rehabilitation after stratification for MRC dyspnea grade

scientific article published on 31 August 2007

Extrapulmonary Manifestations of Chronic Obstructive Pulmonary Disease in a Mouse Model of Chronic Cigarette Smoke Exposure

article

Family Caregiving in Advanced Chronic Organ Failure

scientific article published on May 31, 2011

Family caregiving during 1-year follow-up in individuals with advanced chronic organ failure

scientific article published on 4 February 2015

Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression

scientific article

Frequency and Relevance of Ischemic Electrocardiographic Findings in Patients With Chronic Obstructive Pulmonary Disease

scientific article published on 01 December 2011

Gender differences in the adipose secretome system in chronic obstructive pulmonary disease (COPD): A pivotal role of leptin

scientific article published on 01 March 2011

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease

scientific article

Greater whole-body myofibrillar protein breakdown in cachectic patients with chronic obstructive pulmonary disease

scientific article published on 01 April 2006

Heterogeneity in clinical characteristics and co-morbidities in dyspneic individuals with COPD GOLD D: Findings of the DICES trial

scientific article published on May 22, 2013

Highly elevated C-reactive protein levels in obese patients with COPD: a fat chance?

scientific article published on 18 June 2009

Hyperleptinemia is associated with impaired pulmonary host defense.

scientific article published on June 2016

IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study

scientific article

Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis

scientific article published on March 2015

Identifying Physical Activity Profiles in COPD Patients Using Topic Models

scientific article published on 12 May 2015

Identifying causes of perceptual differences in problematic activities of daily life between patients with COPD and proxies: A qualitative study

scholarly article by Nienke Nakken et al published 29 August 2018 in Australian Occupational Therapy Journal

Impact of exacerbations on adherence and outcomes of pulmonary rehabilitation in patients with COPD.

scientific article published on 31 January 2017

Impact of symptoms of anxiety and depression on COPD Assessment Test scores

scientific article published on 10 October 2013

Impaired health status and care dependency in patients with advanced COPD or chronic heart failure

scientific article published on 27 March 2011

In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization.

scientific article published on 20 February 2006

Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD.

scientific article published in December 2004

Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics.

scientific article published on February 2013

Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease

scientific article published on 30 November 2006

Increased postabsorptive and exercise-induced whole-body glucose production in patients with chronic obstructive pulmonary disease

scientific article published on 05 November 2010

Increased systemic inflammation is a risk factor for COPD exacerbations

scientific article

Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells

scientific article

Inflammatory Biomarkers Improve Clinical Prediction of Mortality in Chronic Obstructive Pulmonary Disease

article

Inhalation therapy in the next decade: Determinants of adherence to treatment in asthma and COPD

scientific article published on 02 February 2018

Inhibition of LPS-induced pulmonary inflammation by specific flavonoids

scientific article

Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine

scientific article published on 4 December 2009

Inhibition of glycogen synthase kinase-3beta activity is sufficient to stimulate myogenic differentiation

scientific article published on 14 September 2005

Insight into advance care planning for patients on dialysis.

scientific article published on 26 July 2012

Instability of Willingness to Accept Life-Sustaining Treatments in Patients With Advanced Chronic Organ Failure During 1 Year

scientific article published on 19 December 2016

Integrating the care of the complex COPD patient.

scientific article published on 18 May 2017

Integration of pulmonary rehabilitation in COPD

scientific article published on 01 January 2008

Involvement of c-Jun N-Terminal Kinase in TNF-α-Driven Remodeling

scientific article published on 22 November 2016

It's more than low BMI: prevalence of cachexia and associated mortality in COPD

scholarly article by Merry-Lynn N McDonald et al published 22 May 2019 in Respiratory Research

Knowledge gaps in patients with COPD and their proxies

scientific article published on 30 October 2017

Left ventricular volume and wall stress are linked to lung function impairment in COPD.

scientific article published in June 2018

Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice

scientific article published on 19 May 2010

Lessons from ECLIPSE: a review of COPD biomarkers

scientific article published on 05 December 2013

Limb muscle dysfunction in COPD: effects of muscle wasting and exercise training

scientific article published in January 2005

Long-Term Intratracheal Lipopolysaccharide Exposure in Mice Results in Chronic Lung Inflammation and Persistent Pathology

scientific article published on 01 January 2002

Longitudinal follow-up of systemic inflammation after acute exacerbations of COPD

scientific article published on 20 July 2007

Lung function changes over time following withdrawal of inhaled corticosteroids in patients with severe COPD.

scientific article published on 19 November 2015

Lung inflammation is associated with reduced pulmonary nucleotide excision repair in vivo

scientific article

Lungs, Bone Marrow, and Adipose Tissue. A Network Approach to the Pathobiology of Chronic Obstructive Pulmonary Disease

scientific article published on 01 December 2013

Management of chronic obstructive pulmonary disease beyond the lungs

scientific article

Metabolic and functional effects of glutamate intake in patients with chronic obstructive pulmonary disease (COPD).

scientific article published on 22 April 2008

Metabolic and structural changes in lower-limb skeletal muscle following neuromuscular electrical stimulation: a systematic review

scientific article

Metabolic effects of glutamine and glutamate ingestion in healthy subjects and in persons with chronic obstructive pulmonary disease

scientific article published in January 2006

Metabolic load during strength training or NMES in individuals with COPD: results from the DICES trial

scientific article

Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease

scientific article published on 15 September 2006

Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD.

scientific article published in August 2003

Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms?

scientific article published on 22 June 2013

Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene

scientific article

Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease

scientific article published on 01 July 2002

Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis

scientific article published on 25 May 2007

Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation

scientific article published on 22 June 2006

Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production

scientific article published on 01 June 2009

Myogenic differentiation during regrowth of atrophied skeletal muscle is associated with inactivation of GSK-3beta

scientific article published on 13 December 2006

NF-κB activation is required for the transition of pulmonary inflammation to muscle atrophy

scientific article published on 26 April 2012

New Normative Values for Handgrip Strength: Results From the UK Biobank

scientific article published on August 16, 2013

New insights in chronic obstructive pulmonary disease and comorbidity

scientific article published on 01 May 2015

New reference values for body composition by bioelectrical impedance analysis in the general population: results from the UK Biobank

scientific article published on 20 April 2014

Nitric oxide and redox signaling in allergic airway inflammation

scientific article

Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation

scholarly article

Normal Weight but Low Muscle Mass and Abdominally Obese: Implications for the Cardiometabolic Risk Profile in Chronic Obstructive Pulmonary Disease

scientific article published on 21 February 2017

Objectively identified comorbidities in COPD: impact on pulmonary rehabilitation outcomes

scientific article

One-year change in health status and subsequent outcomes in COPD.

scientific article published on 17 March 2015

One-year stability of care dependency in patients with advanced chronic organ failure

scientific article published on 4 December 2013

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

scientific article

Optimizing oral nutritional drink supplementation in patients with chronic obstructive pulmonary disease

scientific article

Osteoporosis in COPD outpatients based on bone mineral density and vertebral fractures

scientific article published on 01 March 2011

Osteoporosis in chronic obstructive pulmonary disease

scientific article published on 16 August 2013

Oxygen Uptake, Ventilation, and Symptoms During Low-Frequency Versus High-Frequency NMES in COPD: A Pilot Study

scholarly article by Maurice J. H. Sillen et al published 16 November 2010 in Lung

Patient-Clinician Communication About End-of-Life Care in Patients With Advanced Chronic Organ Failure During One Year

scientific article published on 24 January 2015

Peripheral Artery Disease and Its Clinical Relevance in Patients with Chronic Obstructive Pulmonary Disease in the COPD and Systemic Consequences-Comorbidities Network Study

scientific article published on 17 August 2016

Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype

scientific article published on May 18, 2012

Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort.

scientific article published on 7 August 2014

Personalised pulmonary rehabilitation in COPD.

scientific article published on 28 March 2018

Physical activity monitoring in COPD: compliance and associations with clinical characteristics in a multicenter study

scientific article published on 25 November 2011

Plasma advanced glycation end-products and skin autofluorescence are increased in COPD.

scientific article published on 3 May 2013

Poly (ADP-ribose) polymerase-1-inhibiting flavonoids attenuate cytokine release in blood from male patients with chronic obstructive pulmonary disease or type 2 diabetes.

scientific article published on 25 March 2009

Poor agreement between chart-based and objectively identified comorbidities of COPD.

scientific article published on 4 September 2015

Predicting changes in preferences for life-sustaining treatment among patients with advanced chronic organ failure

scientific article published on 20 October 2011

Prediction and course of symptoms and lung function around an exacerbation in chronic obstructive pulmonary disease

scientific article published on June 6, 2012

Preliminary study on the assessment of visceral adipose tissue using dual-energy x-ray absorptiometry in chronic obstructive pulmonary disease

scientific article published on 04 October 2016

Prevalence of metabolic syndrome in COPD patients and its consequences

scientific article

Problematic activities of daily life are weakly associated with clinical characteristics in COPD.

scientific article published on 17 February 2011

Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study

scientific article

Progression of osteoporosis in patients with COPD: A 3-year follow up study

scientific article published on February 26, 2012

Proposal for a multidimensional staging system for chronic obstructive pulmonary disease

scientific article published in December 2005

Psychosocial consequences of living with breathlessness due to advanced disease

scientific article published on 26 June 2015

Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD

scientific article published on January 16, 2011

Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study

scientific article

Rehabilitation and palliative care in lung fibrosis

scientific article published on August 2009

Rehabilitation decreases exercise-induced oxidative stress in chronic obstructive pulmonary disease

scientific article published on 22 July 2005

Reliability, construct validity and determinants of 6-minute walk test performance in patients with chronic heart failure

scientific article published on 28 February 2017

Reply: minimal or maximal clinically important difference: using death to define MCID.

scientific article

Reproducibility and Validity of the 6-Minute Walk Test Using the Gait Real-Time Analysis Interactive Lab in Patients with COPD and Healthy Elderly

scientific article

Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis.

scientific article published on 22 November 2017

Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results

scientific article published on April 11, 2011

Response of whole-body protein and urea turnover to exercise differs between patients with chronic obstructive pulmonary disease with and without emphysema

scientific article published in April 2003

Responsiveness and MCID Estimates for CAT, CCQ, and HADS in Patients With COPD Undergoing Pulmonary Rehabilitation: A Prospective Analysis

scientific article

Risk factors for osteoporosis in Caucasian patients with moderate chronic obstructive pulmonary disease: A case control study

scientific article published on 09 March 2012

Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease

scientific article published on 5 May 2016

Self-perceived symptoms and care needs of patients with severe to very severe chronic obstructive pulmonary disease, congestive heart failure or chronic renal failure and its consequences for their closest relatives: the research protocol

scientific article

Severity of nocturnal hypoxia and daytime hypercapnia predicts CPAP failure in patients with COPD and obstructive sleep apnea overlap syndrome

scientific article published on 6 May 2016

Sex-related differences in respiratory symptoms: results from the BOLD Study.

scientific article published on September 2013

Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team

scientific article published in May 2014

Silica induces NLRP3 inflammasome activation in human lung epithelial cells

scientific article published on 12 February 2013

Similar matrix alterations in alveolar and small airway walls of COPD patients

scientific article

Six-minute walk distance in patients with chronic obstructive pulmonary disease: Which reference equations should we use?

scientific article published on 9 March 2015

Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization

scientific article published on 21 December 2012

Sleep quality disturbances and cognitive functioning in elderly patients with COPD

scientific article

Spatiotemporal gait characteristics in patients with COPD during the Gait Real-time Analysis Interactive Lab-based 6-minute walk test

scientific article published on 28 December 2017

Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM trial

Striking Similarities in Systemic Factors Contributing to Decreased Exercise Capacity in Patients With Severe Chronic Heart Failure or COPD

scientific article published on 01 May 2003

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

scientific article published on 6 August 2015

Supplementation of soy protein with branched-chain amino acids alters protein metabolism in healthy elderly and even more in patients with chronic obstructive pulmonary disease

scientific article published on 01 February 2007

Survival and physical activity in COPD: a giant leap forward!

scientific article published on 01 August 2011

Symptom Distress in Advanced Chronic Organ Failure: Disagreement among Patients and Family Caregivers

scientific article published on 04 April 2012

Symptoms of anxiety and depression in COPD patients entering pulmonary rehabilitation

scientific article published on August 1, 2010

Symptoms, Comorbidities, and Health Care in Advanced Chronic Obstructive Pulmonary Disease or Chronic Heart Failure

scientific article published on April 21, 2011

Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection?

scientific article published on December 2009

Systemic effects of smoking

scientific article published on May 2007

Systemic inflammation in COPD: is genetic susceptibility a key factor?

scientific article published on March 2006

Systemic inflammation in chronic obstructive pulmonary disease: the role of exacerbations

scientific article published on December 2007

Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients

scientific article

Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease

scientific article published in October 2013

Systems medicine and integrated care to combat chronic noncommunicable diseases

scientific article

Task-related oxygen uptake and symptoms during activities of daily life in CHF patients and healthy subjects

scientific article

The COgnitive-Pulmonary Disease (COgnitive-PD) study: protocol of a longitudinal observational comparative study on neuropsychological functioning of patients with COPD

scientific article

The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline

scientific article

The Impact of Cognitive Impairment on Efficacy of Pulmonary Rehabilitation in Patients With COPD.

scientific article published on 17 January 2017

The Relationship between Cerebral Small Vessel Disease, Hippocampal Volume and Cognitive Functioning in Patients with COPD: An MRI Study

scientific article published on 30 March 2017

The effects of dexamethasone and oxygen in ventilated adult sheep with early phase acute respiratory distress syndrome

scientific article published on 13 December 2014

The last wish of a patient with end stage chronic obstructive pulmonary disease

scientific article

The metabolic response during resistance training and neuromuscular electrical stimulation (NMES) in patients with COPD, a pilot study

scientific article published on 21 February 2008

The physical, mental, and social impact of COPD in a population-based sample: results from the Longitudinal Aging Study Amsterdam

scholarly article by Frits M E Franssen et al published 10 August 2018 in NPJ primary care respiratory medicine

The prevalence of chronic obstructive pulmonary disease in Maastricht, the Netherlands

scientific article published on February 19, 2012

The relationship between coping styles and clinical outcomes in patients with COPD entering pulmonary rehabilitation

scientific article published on June 2013

The respiratory physiome: Clustering based on a comprehensive lung function assessment in patients with COPD

scientific article published in PLoS ONE

The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury.

scientific article published on February 2014

The superexacerbator phenotype in patients with COPD: a descriptive analysis.

scientific article

Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells

scientific article published on 2 November 2005

Thiol redox chemistry: role of protein cysteine oxidation and altered redox homeostasis in allergic inflammation and asthma

scientific article

Transcutaneous carbon-dioxide partial pressure trends during six-minute walk test in patients with very severe COPD.

scientific article published on 11 August 2016

Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort

scientific article published on 13 January 2017

Treating the Systemic Effects of Chronic Obstructive Pulmonary Disease

scientific article published on August 1, 2011

Tumor necrosis factor-alpha +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease

scientific article

Tumor necrosis factor-alpha inhibits myogenesis through redox-dependent and -independent pathways

scientific article published on September 2002

Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization

scientific article published on February 2004

Validation of the oxycon mobile metabolic system in healthy subjects

scientific article published on March 2012

Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD.

scientific article

Viral-bacterial interactions in the respiratory tract

scientific article published on 18 October 2016

Vitamin D status is associated with bone mineral density and functional exercise capacity in patients with chronic obstructive pulmonary disease

scientific article published on 2 April 2012

Vitamin D, vitamin D binding protein, lung function and structure in COPD.

scientific article published in July 2013

Vitamin K deficiency: the linking pin between COPD and cardiovascular diseases?

scientific article

Volatile organic compounds discriminate between eosinophilic and neutrophilic inflammation in vitro

scientific article published on February 2016

Whole-Body versus Local DXA-Scan for the Diagnosis of Osteoporosis in COPD Patients

scientific article published on February 7, 2010

α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts

scientific article