List of works by Todd M Allen

A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais

scientific article

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells

scientific article

Adaptation of HIV-1 to human leukocyte antigen class I

scientific article published on 25 February 2009

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

scientific article (publication date: 6 May 2008)

Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells

scientific article published on 25 November 2016

Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

scientific article published on October 2016

Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes

scientific article

CD8 Epitope Escape and Reversion in Acute HCV Infection

scientific article

Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus

scientific article

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes

scientific article published on 20 December 2005

Coordinate linkage of HIV evolution reveals regions of immunological vulnerability

scientific article

Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells

scientific article published on 14 June 2013

De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection

scientific article

Definition of the viral targets of protective HIV-1-specific T cell responses

scientific article published on 7 December 2011

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus

scientific article

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians

scientific article published in May 2004

Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes

scientific article published on 21 January 2009

Differential regulation of toll-like receptor pathways in acute and chronic HIV-1 infection

scientific article published on March 2012

Differentiation of exhausted CD8<sup>+</sup> T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

scientific article published on 26 July 2021

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

scientific article published in December 2004

Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo

scientific article published on 31 August 2020

Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection

scientific article

Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

scientific article

Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

scientific article

Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome

scientific article published on January 2009

Epigenetic scars of CD8<sup>+</sup> T cell exhaustion persist after cure of chronic infection in humans

scientific article published on 26 July 2021

Erratum: addendum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

scientific article published in Nature

Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.

scientific article

Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells

scientific article published on March 2004

Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire

scientific article published on December 2005

Frequent and strong antibody-mediated natural killer cell activation in response to HIV-1 Env in individuals with chronic HIV-1 infection

scientific article

Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy

scientific article

Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes

scientific article published on 18 June 2008

Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein

scientific article published on 11 May 2020

HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity

scientific article

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

scientific article published in November 2002

HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.

scientific article published in June 2005

HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha

scientific article published in April 2004

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

scientific article

HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering

scientific article published on 25 February 2009

HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition

scientific article published on 30 December 2008

HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load

scientific article

HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1.

scientific article published on 29 October 2008

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

scientific article

High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection

scientific article published on September 2004

Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non genotype 1 infection

scientific article (publication date: September 2007)

Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection.

scientific article published on 15 August 2006

Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection

scientific article

Increased detection of HIV-specific T cell responses by combination of central sequences with comparable immunogenicity

article

Increased sequence diversity coverage improves detection of HIV-specific T cell responses

scientific article published in November 2007

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection

scientific article published in December 2003

Limited sequence evolution within persistently targeted CD8 epitopes in chronic human immunodeficiency virus type 1 infection

scientific article

Loss of HIV-1-specific T-cell responses associated with very rapid HIV-1 disease progression

scientific article published in April 2007

Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection

scientific article published on 9 July 2008

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes

scientific article published on 22 November 2006

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients

scientific article (publication date: December 2008)

PriSM: a primer selection and matching tool for amplification and sequencing of viral genomes ⬇️

scientific article published on November 9, 2010

Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.

scientific article

Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers

scientific article published on February 2011

Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control

scientific article

STI and beyond: the prospects of boosting anti-HIV immune responses

scientific article

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

scientific article

Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection

scientific article published on 7 February 2007

Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution

scientific article

Sensitive population profiling and genome assembly of HIV and Flaviviruses using ultra-deep sequencing technologies.

scientific article published on 11 October 2010

Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes

scientific article

Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid

scientific article published on 2 April 2008

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

scientific article published on 10 June 2012

Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection

scientific article

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

scientific article

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

scientific article

Transmission and long-term stability of compensated CD8 escape mutations

scientific article published on 17 December 2008

Use of a novel GFP reporter cell line to examine replication capacity of CXCR4- and CCR5-tropic HIV-1 by flow cytometry

scientific article

Viral Evolution and Escape during Acute HIV‐1 Infection ⬇️

scientific article published on October 15, 2010

Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

scientific article published on 8 March 2012

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