List of works - Xu G Yu

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

scientific article published on 29 January 2018

A cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllers

scientific article

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells

scientific article

Association between HIV Type 1-specific T cell responses and CD4+ T cell counts or CD4+:CD8+ T cell ratios in HIV Type 1 subtype B infection in China

scientific article published on August 2006

CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21

scientific article

CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

scientific article

Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth

scientific article

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

scientific article published on 19 June 2017

Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection

scientific article

De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection

scientific article

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians

scientific article published in May 2004

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

scientific article published on 26 August 2020

Early antiretroviral therapy in neonates with HIV-1 infection restricts viral reservoir size and induces a distinct innate immune profile

scientific article published on 01 November 2019

Elite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors

scientific article published on 12 July 2016

Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

scientific article

Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells

scientific article

Erratum: addendum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

scientific article published in Nature

Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection

scientific article

HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity

scientific article

HIV-1 persistence in CD4+ T cells with stem cell-like properties

scientific article published on 12 January 2014

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

scientific article published in November 2002

HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.

scientific article published in June 2005

HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha

scientific article published in April 2004

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

scientific article

High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level.

scientific article published in September 2005

Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC)

scientific article

Identification of HLA-A11-restricted HIV-1-specific cytotoxic T-lymphocyte epitopes in China

scientific article published on January 2007

Impact of HLA class I functional divergence on HIV control

scientific article published on 19 January 2024

Impact of intrapeptide epitope location on CD8 T cell recognition

Important contribution of p15 Gag-specific responses to the total Gag-specific CTL responses

scientific article published on February 2002

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection

scientific article published in December 2003

Inter-clade cross-reactivity of HIV-1-specific T cell responses in human immunodeficiency virus type 1 infection in China

scientific article published on March 2007

LILRB2 interaction with HLA class I correlates with control of HIV-1 infection

scientific article

Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers

scientific article

Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells

scientific article

Metabolic pathway activation distinguish transcriptional signatures of CD8+ T cells from HIV-1 elite controllers

article

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes

scientific article published on 22 November 2006

Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers

scientific article published on 11 June 2015

Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China

scientific article

Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties

scientific article published on 20 May 2015

Random T-cell receptor recruitment in human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells from genetically identical twins infected with the same HIV-1 strain

scientific article published on 5 September 2007

Relative dominance of Env-gp41-specific cytotoxic T lymphocytes responses in HIV-1 advanced infection

scientific article published in May 2008

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

scientific article

Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection

scientific article published on 7 February 2007

Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers

scientific article published on 15 December 2021

Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid

scientific article published on 2 April 2008

T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily

article

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

scientific article published on 10 June 2012

Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors

scientific article published on 26 August 2008

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

scientific article

Unravelling the mechanisms of durable control of HIV-1.

scientific article published on July 2013

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

scientific article

Virus detection using nanoparticles and deep neural network-enabled smartphone system

scientific article published on 16 December 2020

List of works by Xu G Yu

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

A cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllers

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells

Association between HIV Type 1-specific T cell responses and CD4+ T cell counts or CD4+:CD8+ T cell ratios in HIV Type 1 subtype B infection in China

CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21

CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection

De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

Early antiretroviral therapy in neonates with HIV-1 infection restricts viral reservoir size and induces a distinct innate immune profile

Elite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors

Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells

Erratum: addendum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection

HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity

HIV-1 persistence in CD4+ T cells with stem cell-like properties

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.

HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level.

Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC)

Identification of HLA-A11-restricted HIV-1-specific cytotoxic T-lymphocyte epitopes in China

Impact of HLA class I functional divergence on HIV control

Impact of intrapeptide epitope location on CD8 T cell recognition

Important contribution of p15 Gag-specific responses to the total Gag-specific CTL responses

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection

Inter-clade cross-reactivity of HIV-1-specific T cell responses in human immunodeficiency virus type 1 infection in China

LILRB2 interaction with HLA class I correlates with control of HIV-1 infection

Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers

Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells

Metabolic pathway activation distinguish transcriptional signatures of CD8+ T cells from HIV-1 elite controllers

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes

Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers

Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China

Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties

Random T-cell receptor recruitment in human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells from genetically identical twins infected with the same HIV-1 strain

Relative dominance of Env-gp41-specific cytotoxic T lymphocytes responses in HIV-1 advanced infection

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection

Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers

Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid

T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

Unravelling the mechanisms of durable control of HIV-1.

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

Virus detection using nanoparticles and deep neural network-enabled smartphone system