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List of works by Jason G Kettle

Covalent inhibitors of the GTPase KRASG12C: a review of the patent literature

scientific article published on 08 January 2020

Discovery and pharmacological characterization of AZD3229, a potent KIT/PDGFRα inhibitor for treatment of gastrointestinal stromal tumors

scientific article published on 01 April 2020

Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

scientific article published on 24 September 2018

Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C

scientific article published on 13 February 2020

The pharmacokinetic-pharmacodynamic (PKPD) relationships of AZD3229, a novel and selective inhibitor of cKIT, in a range of mouse xenograft models of GIST

scientific article published on 27 March 2020

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