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List of works by Mark T Heise

A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge ⬇️

scientific article published on September 21, 2011

A Protective Role for Complement C3 Protein during Pandemic 2009 H1N1 and H5N1 Influenza A Virus Infection ⬇️

scientific article published on March 9, 2011

A Reverse Genetics Platform That Spans the Zika Virus Family Tree

scientific article (publication date: 7 March 2017)

A Universal Next-Generation Sequencing Protocol To Generate Noninfectious Barcoded cDNA Libraries from High-Containment RNA Viruses

scientific article

A determinant of Sindbis virus neurovirulence enables efficient disruption of Jak/STAT signaling.

scientific article published on 25 August 2010

A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner

scientific article

A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant

scientific article

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

scientific article

A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence

scientific article

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

scientific article

A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilization

scientific article

Abstract SY04-02: Dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner

Acute and chronic B cell depletion disrupts CD4+ and CD8+ T cell homeostasis and expansion during acute viral infection in mice

scientific article

An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivo

scientific article published on 17 October 2012

An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis

scientific article

Animal Models of Chikungunya Virus Infection and Disease.

scientific article

Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts

scientific article

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

scientific article published on 21 September 2020

CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection

scientific article published on 02 March 2016

Characterization of Ross River virus tropism and virus-induced inflammation in a mouse model of viral arthritis and myositis

scientific article

Chemokines and viruses: friends or foes?

scientific article

Chikungunya Virus: Current Perspectives on a Reemerging Virus.

scientific article published on June 2016

Chikungunya virus transmission--more than meets the eye.

scientific article published on 15 June 2012

Chikungunya: a re-emerging virus

scientific article

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

article

Complement contributes to inflammatory tissue destruction in a mouse model of Ross River virus-induced disease

scientific article

Complement receptor 3 promotes severe ross river virus-induced disease

scientific article published on 10 September 2008

Complete Genome Sequences of 15 Chikungunya Virus Isolates from Puerto Rico

scientific article published on 6 July 2017

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

scientific article published on 01 April 2020

Coronavirus Host Range Expansion and Middle East Respiratory Syndrome Coronavirus Emergence: Biochemical Mechanisms and Evolutionary Perspectives

scientific article published on 7 August 2015

Correction: Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants.

scientific article published on 27 February 2007

Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice

scientific article published on 13 March 2013

Development and characterization of a Rift Valley fever virus cell-cell fusion assay using alphavirus replicon vectors

scientific article published on 30 August 2006

Development of a Broadly Accessible Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine Platform

scientific article published on 14 March 2018

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus

scientific article (publication date: 2013)

Diallel analysis reveals Mx1-dependent and Mx1-independent effects on response to influenza A virus in mice

Differential Induction of Type I Interferon Responses in Myeloid Dendritic Cells by Mosquito and Mammalian-Cell-Derived Alphaviruses

scientific article

Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

scientific article published on 14 November 2017

Editorial overview: viral pathogenesis: dealing with complexity in virus-induced disease

scientific article published on 2 June 2014

Emerging Alphaviruses are Sensitive to Cellular States Induced by a Novel Small Molecule Agonist of the STING Pathway

scientific article published on 20 December 2017

Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice

scientific article published on February 2012

Genetic analysis of complex traits in the emerging Collaborative Cross

scientific article

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

scientific article published on 9 October 2015

Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression

scientific article

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection

scientific article published on 4 February 2015

High rates of o'nyong nyong and Chikungunya virus transmission in coastal Kenya

scientific article

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

scientific article

Identification of adult mouse neurovirulence determinants of the Sindbis virus strain AR86.

scientific article

Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model

scientific article (publication date: December 2016)

Immune Predictors of Mortality After Ribonucleic Acid Virus Infection

scientific article published on 01 March 2020

Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection

scientific article published on 15 November 2011

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

scientific article published in July 2015

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

scientific article published in 2015

Mannose binding lectin is required for alphavirus-induced arthritis/myositis

scientific article

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross

scientific article (publication date: February 2013)

Modulation of cellular tropism and innate antiviral response by viral glycans

scientific article published on 25 June 2009

Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein

scientific article

Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection

scientific article

Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

scientific article

Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model

scientific article

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

scientific article

Myd88-dependent toll-like receptor 7 signaling mediates protection from severe Ross River virus-induced disease in mice

scientific article

NLRX1 is a regulator of mitochondrial antiviral immunity

scientific article

Natural resistance-associated macrophage protein is a cellular receptor for sindbis virus in both insect and mammalian hosts

scientific article

Of mice and men: the host response to influenza virus infection

scientific article published on 15 June 2018

Permissivity of Dipeptidyl Peptidase 4 Orthologs to Middle East Respiratory Syndrome Coronavirus Is Governed by Glycosylation and Other Complex Determinants

scientific article

Protective and Pathogenic Responses to Chikungunya Virus Infection

scientific article published on March 2015

Quantitative genetics in the study of virus-induced disease

scientific article published on January 2014

Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.

scientific article

Regulatory B Cell (B10 Cell) Expansion during Listeria Infection Governs Innate and Cellular Immune Responses in Mice ⬇️

scientific article published on December 28, 2012

Residue 82 of the Chikungunya virus E2 attachment protein modulates viral dissemination and arthritis in mice

scientific article

Ross River virus envelope glycans contribute to disease through activation of the host complement system.

scientific article published on 8 January 2018

Ross River virus envelope glycans contribute to type I interferon production in myeloid dendritic cells

scientific article published on 15 October 2008

Ross River virus: molecular and cellular aspects of disease pathogenesis

scientific article

SARS coronavirus accessory ORFs encode luxury functions

scientific article published on January 2006

SARS coronavirus and innate immunity

scientific article published on 23 April 2007

SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism

scientific article

Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane

scientific article published on 27 June 2007

Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs.

scientific article

Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus

scientific article

Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice

scientific article published on 16 May 2007

The Decision to Publish Gutierrez-Alvarez et al., "Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice"

scientific article published on 03 November 2020

The Viral Interferon Regulatory Factors of Kaposi's Sarcoma-Associated Herpesvirus Differ in Their Inhibition of Interferon Activation Mediated by Toll-Like Receptor 3 ⬇️

scientific article published on October 31, 2012

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

scientific article published on 26 May 2015

Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population

scientific article published on 14 October 2016

Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling

scientific article

Vaccination with DNA plasmids expressing Gn coupled to C3d or alphavirus replicons expressing gn protects mice against Rift Valley fever virus

scientific article

Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants

scientific article (publication date: December 2006)

Venezuelan equine encephalitis virus disrupts STAT1 signaling by distinct mechanisms independent of host shutoff.

scientific article published on 5 August 2009

Zika virus infection in Collaborative Cross mice

scientific article published on 08 July 2019

γδ T Cells Play a Protective Role in Chikungunya Virus-Induced Disease

scientific article

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