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List of works by Paul S. Gaynon

"The Second Time is Sweeter After All".

scientific article published in February 2017

A Phase I Study of Quizartinib Combined with Chemotherapy in Relapsed Childhood Leukemia: A Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study

scientific article published on 26 February 2016

A computer-based system for management of clinical and laboratory data of a comprehensive sickle cell center.

scientific article published on October 1974

A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia

scientific article published on 10 September 2009

A neoplasm with FIP1L1-PDGFRA fusion presenting as pediatric T-cell lymphoblastic leukemia/lymphoma without eosinophilia.

scientific article published on 3 August 2017

A pharmacoeconomic analysis of pegaspargase versus native Escherichia coli L-asparaginase for the treatment of children with standard-risk, acute lymphoblastic leukemia: the Children's Cancer Group study (CCG-1962)

scientific article published on 01 March 2002

A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from TACL consortium

scientific article published on 16 January 2018

A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childho

scientific article

A phase I study of carboplatin in children with acute leukemia in bone marrow relapse. A report from the Childrens Cancer Group

scientific article published on 01 August 1993

A phase II study of carboplatin as a treatment for children with acute leukemia recurring in bone marrow: a report of the Children's Cancer Group

scientific article published on 01 July 1997

A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study

scientific article published in March 2002

A remembrance: James B. Nachman 1948–2011 ⬇️

scientific article published on October 1, 2011

A retrieval system for a library of pathology reports, slides and kodachromes

scientific article published on July 1972

ABT-751 in Relapsed Childhood Acute Lymphoblastic Leukemia ⬇️

scientific article published on 01 October 2012

ALL and osteonecrosis

scientific article published in October 2015

Abnormalities of chromosome bands 13q12 to 13q14 in childhood acute lymphoblastic leukemia

scientific article published on 01 November 2000

Abnormalities of chromosome bands 15q13-15 in childhood acute lymphoblastic leukemia

scientific article published on 01 February 2002

Acute leukemia in children.

scientific article published on July 1995

Allergic reactions and antiasparaginase antibodies in children with high-risk acute lymphoblastic leukemia: A children's oncology group report

scientific article published on 26 August 2015

Altered patterns of T cell cytokine production induced by relapsed pre-B ALL cells.

scientific article published in December 2003

An adjustment for patient heterogeneity in the design of two-stage phase II trials

scientific article published in September 2009

An automated parsing routine for diagnostic statements of surgical pathology reports

scientific article published on 01 July 1971

Anaphylactic reaction to etoposide phosphate ⬇️

scientific article published on April 22, 2012

Asparaginase antibody and asparaginase activity in children with higher-risk acute lymphoblastic leukemia: Children's Cancer Group Study CCG-1961.

scientific article published in April 2004

Asparagine depletion after pegylated E. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: a Children's Oncology Group study (CCG-1941).

scientific article

Association of delivered drug dose and outcome for children with acute lymphoblastic leukemia and unfavorable presenting features

scientific article published on 01 January 1991

Augmented Berlin-Frankfurt-Munster therapy abrogates the adverse prognostic significance of slow early response to induction chemotherapy for children and adolescents with acute lymphoblastic leukemia and unfavorable presenting features: a report fr

scientific article

Bone marrow leukemic progenitor cell content in pediatric T-lineage acute lymphoblastic leukemia patients with an isolated extramedullary first relapse

scientific article published on 01 January 2001

Bone marrow transplantation versus prolonged intensive chemotherapy for children with acute lymphoblastic leukemia and an initial bone marrow relapse within 12 months of the completion of primary therapy: Children's Oncology Group study CCG-1941.

scientific article

Bortezomib with chemotherapy is highly active in advanced B-precursor acute lymphoblastic leukemia: Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study ⬇️

scientific article published on May 31, 2012

Bortezomib, Dexamethasone, Mitoxantrone, and Vinorelbine (BDMV): An Active Reinduction Regimen for Children With Relapsed Acute Lymphoblastic Leukemia and Asparaginase Intolerance

scientific article published on July 2016

CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells

scientific article

CD22 Exon 12 deletion is a characteristic genetic defect of therapy‐refractory clones in paediatric acute lymphoblastic leukaemia ⬇️

scientific article published on October 21, 2011

CNS-Directed Therapy for Childhood Acute Lymphoblastic Leukemia: Childhood ALL Collaborative Group Overview of 43 Randomized Trials ⬇️

scientific article published on May 1, 2003

Changes of amino acid serum levels in pediatric patients with higher-risk acute lymphoblastic leukemia (CCG-1961).

scientific article published in March 2004

Childhood acute lymphoblastic leukaemia and relapse

scientific article

Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study

scientific article published on 18 August 2005

Clinical features and treatment outcome of childhood T-lineage acute lymphoblastic leukemia according to the apparent maturational stage of T-lineage leukemic blasts: a Children's Cancer Group study

scientific article published on 01 June 1997

Clinical significance of deletions of chromosome arm 6q in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group

scientific article published on 01 February 2000

Clinical significance of translocation t(1;19) in childhood acute lymphoblastic leukemia in the context of contemporary therapies: a report from the Children's Cancer Group ⬇️

scientific article published on 01 February 1998

Comparative Toxicity by Sex Among Children Treated for Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group

scientific article

Constitutive function of the Ikaros transcription factor in primary leukemia cells from pediatric newly diagnosed high-risk and relapsed B-precursor ALL patients

scientific article

Continuous Infusion of 5-Azacytidine as Induction for Acute Nonlymphocytic Leukemia in Patients with Previous Exposure to 5-Azacytidine ⬇️

scientific article published on 01 January 1983

Craniospinal irradiation for acute lymphoblastic leukemia with central nervous system disease at diagnosis: a report from the Children's Cancer Group

scientific article published on 01 August 1996

Cytoreduction and prognosis in acute lymphoblastic leukemia--the importance of early marrow response: report from the Childrens Cancer Group

scientific article published on 01 February 1996

Deamination of glutamine is a prerequisite for optimal asparagine deamination by asparaginases in vivo (CCG-1961).

scientific article

Deletion of 7p or monosomy 7 in pediatric acute lymphoblastic leukemia is an adverse prognostic factor: a report from the Children's Cancer Group

scientific article published in May 2004

Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group

scientific article published on 16 January 2003

Duration of hospitalization as a measure of cost on Children's Cancer Group acute lymphoblastic leukemia studies

scientific article published on 01 April 2001

Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group

scientific article

Effect of alternate-week versus continuous dexamethasone scheduling on the risk of osteonecrosis in paediatric patients with acute lymphoblastic leukaemia: results from the CCG-1961 randomised cohort trial ⬇️

scientific article published on August 15, 2012

End of induction minimal residual disease alone is not a useful determinant for risk stratified therapy in pediatric T-cell acute lymphoblastic leukemia

scientific article

Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group

scientific article

Expression of BCR-ABL, E2A-PBX1, and MLL-AF4 Fusion Transcripts in Newly Diagnosed Children with Acute Lymphoblastic Leukemia: A Children's Cancer Group Initiative ⬇️

scientific article published on 01 June 1997

Expression of TEL-AML1 Fusion Transcripts and Response to Induction Therapy in Standard Risk Acute Lymphoblastic Leukemia

scientific article published on 01 June 2001

Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia

scientific article (publication date: December 1999)

Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study

scientific article

Feasibility Study of a Novel Experimental Induction Protocol Combining B43-PAP (Anti-CD19) Immunotoxin With Standard Induction Chemotherapy in Children and Adolescents With Relapsed B-Lineage ALL: A Report From the Children's Oncology Group

scientific article

First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases.

scientific article

Frequency and clinical significance of cytogenetic abnormalities in pediatric T-lineage acute lymphoblastic leukemia: a report from the Children's Cancer Group ⬇️

scientific article published on April 1, 1998

From where do clinical trials come?

scientific article published in March 2002

Glucocorticosteroid therapy in childhood acute lymphoblastic leukemia

scientific article

Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia

scientific article

High-resolution melting curve analysis, a rapid and affordable method for mutation analysis in childhood acute myeloid leukemia

scientific article

Historical Controls?

scientific article published on 28 February 2017

Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group.

scientific article published on 31 March 2014

Importance of the day 7 bone marrow biopsy as a prognostic measure of the outcome in children with acute lymphoblastic leukemia

scientific article published on 01 July 1997

Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group ⬇️

scientific article published on March 12, 2012

Improved clinical outcome for children with T-lineage acute lymphoblastic leukemia after contemporary chemotherapy: a Children's Cancer Group Study

scientific article published on 01 December 1996

Improved disease-free survival of children with acute lymphoblastic leukemia at high risk for early relapse with the New York regimen--a new intensive therapy protocol: a report from the Childrens Cancer Study Group

scientific article published on May 1986

Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study

scientific article published on 05 October 2009

Improved therapy for children with acute lymphoblastic leukemia and unfavorable presenting features: a follow-up report of the Childrens Cancer Group Study CCG-106

scientific article published on 01 November 1993

Improving access to novel agents for childhood leukemia

scientific article published on 11 February 2015

Increased post-induction intensification improves outcome in children and adolescents with a markedly elevated white blood cell count (≥200 × 10(9) /l) with T cell acute lymphoblastic leukaemia but not B cell disease: a report from the Children's On

scientific article

Intensification of Therapy for Children With Lower-Risk Acute Lymphoblastic Leukemia: Long-Term Follow-Up of Patients Treated on Children’s Cancer Group Trial 1881 ⬇️

scientific article published on 01 May 2003

Intensive therapy for children with acute lymphoblastic leukaemia and unfavourable presenting features. Early conclusions of study CCG-106 by the Childrens Cancer Study Group

scientific article published in October 1988

Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic l

scientific article published on 11 April 2006

James B. Nachman, 1948 to 2011: a remembrance

scientific article published in August 2011

Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group study AALL0031.

scientific article

Long-term results of large prospective trials in childhood acute lymphoblastic leukemia

scientific article published on 01 December 2000

Long-term results of the children's cancer group studies for childhood acute lymphoblastic leukemia 1983-2002: a Children's Oncology Group Report

scientific article

Low incidence of second neoplasms among children diagnosed with acute lymphoblastic leukemia after 1983.

scientific article published in June 2002

Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952

scientific article published on 01 January 2005

Mercaptopurine in childhood acute lymphoblastic leukaemia

scientific article

Myeloid lineage switch following chimeric antigen receptor T-cell therapy in a patient with TCF3-ZNF384 fusion-positive B-lymphoblastic leukemia

scientific article published on 24 May 2018

Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia ⬇️

scientific article published on April 8, 2013

No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities

scientific article published on 01 April 2005

Obesity and outcome in pediatric acute lymphoblastic leukemia

scientific article published in May 2007

Oligoclonality and new agent evaluation in acute lymphoblastic leukaemia

scientific article published on 25 May 2016

Once upon a time--a personal view on episodes in leukemia research in Germany, and beyond ⬇️

scientific article published on May 22, 2013

Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial

scientific article

Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952.

scientific article published in December 2007

Outcome for children treated for relapsed or refractory acute myelogenous leukemia (rAML): a Therapeutic Advances in Childhood Leukemia (TACL) Consortium study

scientific article published on September 2010

Outcome of Children with Standard-Risk T-Lineage Acute Lymphoblastic Leukemia--Comparison among Different Treatment Strategies

scientific article

Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium study

scientific article

Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region

scientific article published on 01 June 2002

Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia

scientific article published on 01 April 2000

Outcomes after induction failure in childhood acute lymphoblastic leukemia

scientific article

POLARS: A pathology on-line logging and reporting system ⬇️

scientific article published on 01 February 1974

Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia ⬇️

scientific article published on 03 October 2011

Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia (TACL) consortium

scientific article published in August 2010

Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia

scientific article published on 01 April 2006

Phase II study of clofarabine in pediatric patients with refractory or relapsed acute myeloid leukemia

scientific article published on 03 August 2009

Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group

scientific article published in May 2005

Philadelphia chromosome-negative very high-risk acute lymphoblastic leukemia in children and adolescents: results from Children's Oncology Group Study AALL0031

scientific article

Ponte di Legno Working Group: statement on the right of children with leukemia to have full access to essential treatment and report on the Sixth International Childhood Acute Lymphoblastic Leukemia Workshop

scientific article published on 01 June 2004

Poor treatment outcome of Philadelphia chromosome-positive pediatric acute lymphoblastic leukemia despite intensive chemotherapy

scientific article published on 01 March 1999

Population pharmacokinetics of clofarabine and its metabolite 6-ketoclofarabine in adult and pediatric patients with cancer

scientific article published on 26 June 2010

Population pharmacokinetics of clofarabine, a second-generation nucleoside analog, in pediatric patients with acute leukemia

scientific article published in November 2004

Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group ⬇️

scientific article published on December 30, 2010

Preponderant mitotic activity of nonleukemic cells plays an important role in failures to detect abnormal clone in childhood acute lymphoblastic leukemia

scientific article published in July 2003

Profile of a dictionary compiled from scanning over one million words of surgical pathology narrative text

scientific article published on 01 August 1980

Prognostic Significance of B-Lineage Leukemic Cell Growth in SCID Mice: A Children's Cancer Group Study ⬇️

scientific article published on 01 August 1998

Prognostic impact of trisomies of chromosomes 10, 17, and 5 among children with acute lymphoblastic leukemia and high hyperdiploidy (> 50 chromosomes)

scientific article published on 01 May 2000

Prospective monitoring for invasive aspergillosis using galactomannan and polymerase chain reaction in high risk pediatric patients

scientific article

RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia.

scientific article published in April 2004

Racial and ethnic differences in survival of children with acute lymphoblastic leukemia

scientific article published on September 2002

Recent advances in acute lymphoblastic leukemia in children and adolescents: an expert panel discussion

scientific article published on December 2013

Redefining treatment failure for pediatric acute leukemia in the era of minimal residual disease testing

scientific article published on 30 November 2017

Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study

scientific article published in September 2003

Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected]

scientific article published on August 2008

Relapsed acute lymphoblastic leukemia: current status and future opportunities

scientific article

Remission is good - relapse is bad.

scientific article published in January 2018

Reply: T-Cell Acute Lymphoblastic Leukemia, Minimal Residual Disease, and Lymphocyte Recovery

scientific article

Response of children with high-risk acute lymphoblastic leukemia treated with and without cranial irradiation: a report from the Children's Cancer Group ⬇️

scientific article published on March 1, 1998

Response to Donadieu and Hill "Clinical trials in childhood acute lymphoblastic leukemia: a common prognostic classification and a common induction therapy are now warranted".

scientific article published in August 2002

Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG).

scientific article published on 26 September 2006

Role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of pediatric acute lymphoblastic leukemia: update of the 2005 evidence-based review

scientific article published on 29 December 2011

Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome

scientific article published on 01 April 2004

Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia

scientific article published in July 2007

Statement by members of the Ponte di Legno Group on the right of children to have full access to essential treatment for acute lymphoblastic leukemia

scientific article published on 01 August 2004

Statement by members of the Ponte di Legno group on the right of children with leukemia to have full access to essential treatment for acute lymphoblastic leukemia

scientific article published on 01 January 2005

Subcutaneous Panniculitis-like T-cell lymphoma in two pediatric patients: an HIV-positive adolescent and a 4-month-old infant

scientific article published on October 23, 2012

Survival after relapse in childhood acute lymphoblastic leukemia: impact of site and time to first relapse--the Children's Cancer Group Experience

scientific article published on 01 April 1998

Ten-year survival of children with acute lymphoblastic leukemia: a report from the Children's Oncology Group

scientific article published on 01 June 2008

The Role of Cytotoxic Therapy with Hematopoietic Stem Cell Transplantation in the Treatment of Pediatric Acute Lymphoblastic Leukemia: Update of the 2005 Evidence-Based Review ⬇️

scientific article published on 07 April 2012

The effect of initial management of hyperleukocytosis on early complications and outcome of children with acute lymphoblastic leukemia

scientific article published on September 1988

The principle and practice of reinduction therapy (in ALL): repetita iuvant! ⬇️

scientific article published on May 22, 2013

The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review.

scientific article

The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in children: an evidence-based review

scientific article

The role of radiation therapy in the treatment of acute lymphoblastic leukemia with lymphomatous presentation: a report from the Childrens Cancer Group

scientific article published on 01 December 1993

The use of glucocorticoids in acute lymphoblastic leukemia of childhood. Molecular, cellular, and clinical considerations.

scientific article published on February 1995

Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL): Overview and introduction to the proceedings of the 2016 TACL investigator meeting

scientific article published on 9 November 2017

Tibial stress fracture mimicking neuroblastoma metastasis in two young children ⬇️

scientific article published on 01 May 1995

Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference

scientific article

Treating refractory leukemias in childhood, role of clofarabine

scientific article

Treatment adherence and 6-mercaptopurine metabolites

scientific article

Treatment of Human B-Cell Precursor Leukemia in SCID Mice by Using a Combination of the Anti-CD19 Immunotoxin B43-PAP with the Standard Chemotherapeutic Drugs Vincristine, Methylprednisolone, and L-Asparaginase ⬇️

scientific article published on 01 September 1998

Treatment of pediatric acute lymphoblastic leukemia: progress achieved and challenges remaining

scientific article published on July 2007

Treatment outcome and prognostic factors for infants with acute lymphoblastic leukemia treated on two consecutive trials of the Children's Cancer Group

scientific article published on February 1999

Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia

scientific article published on January 1996

What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies

scientific article published on 23 May 2008

Young adults 16-21 years of age at diagnosis entered on Childrens Cancer Group acute lymphoblastic leukemia and acute myeloblastic leukemia protocols. Results of treatment

scientific article published on 01 May 1993

Young adults with acute lymphoblastic leukemia have an excellent outcome with chemotherapy alone and benefit from intensive postinduction treatment: a report from the children's oncology group

scientific article

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