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List of works by Takashi Kohno

A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network

scientific article published on 07 July 2018

A Two-Gene Prognostic Classifier for Early-Stage Lung Squamous Cell Carcinoma in Multiple Large-Scale and Geographically Diverse Cohorts.

scientific article published on 6 September 2016

A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene.

scientific article

A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing.

scientific article published on 7 June 2018

A gene-alteration profile of human lung cancer cell lines.

scientific article

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population ⬇️

scientific article published on July 15, 2012

A mouse model of KIF5B-RET fusion-dependent lung tumorigenesis.

scientific article published on 26 July 2014

A secondary RET mutation in the activation loop conferring resistance to vandetanib.

scientific article published on 12 February 2018

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

scientific article

A three-microRNA signature predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma.

scientific article published on 20 August 2014

ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation

scientific article published on 16 November 2020

Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines

scientific article

Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples

scientific article

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers

scientific article published in July 2015

An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation-Negative Pancreatic Ductal Adenocarcinoma

scientific article published on 6 February 2017

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

scientific article published on 26 December 2016

Association of CYP19A1 polymorphisms with risks for atypical adenomatous hyperplasia and bronchioloalveolar carcinoma in the lungs ⬇️

scientific article published on August 5, 2010

Association of DNA Repair Gene Polymorphisms With Response to Platinum-Based Doublet Chemotherapy in Patients With Non–Small-Cell Lung Cancer ⬇️

scientific article published on October 12, 2010

Association of KRAS polymorphisms with risk for lung adenocarcinoma accompanied by atypical adenomatous hyperplasias

Association of amino acid substitution polymorphisms in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk.

scientific article published in May 2005

Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples

scientific article

Association of p16 homozygous deletions with clinicopathologic characteristics and EGFR/KRAS/p53 mutations in lung adenocarcinoma

scientific article

Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk.

scientific article

Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk

scientific article published on 23 June 2006

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma

scientific article published on 09 August 2016

BRAF V600E mutation is a potential therapeutic target for a small subset of synovial sarcoma

scientific article published on 01 April 2020

Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium

scientific article published on 01 June 2019

Bright-Field Dual-Color Chromogenic In Situ Hybridization for Diagnosing Echinoderm Microtubule-Associated Protein-Like 4-Anaplastic Lymphoma Kinase-Positive Lung Adenocarcinomas ⬇️

scientific article published on October 1, 2011

C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe.

scientific article published on 17 April 2014

CBP and p300 Histone Acetyltransferases Contribute to Homologous Recombination by Transcriptionally Activating the BRCA1 and RAD51 Genes ⬇️

scientific article published on December 20, 2012

CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma

scientific article

Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein

scientific article

Carbon-ion beam irradiation kills X-ray-resistant p53-null cancer cells by inducing mitotic catastrophe

scientific article

Characterization of cancer omics and drug perturbations in panels of lung cancer cells

scientific article published on 20 December 2019

Chromatin-regulating proteins as targets for cancer therapy

scientific article

Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression.

scientific article

Circulating exosomal microRNAs as biomarkers of colon cancer.

scientific article

Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)

scientific article published on 29 November 2020

Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer

scientific article

Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities

scientific article published on 3 March 2017

Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma

scientific article published on 01 July 2002

Clonal Hematopoiesis From Next Generation Sequencing of Plasma From a Patient With Lung Adenocarcinoma: A Case Report

scientific article published on 13 February 2020

Clonal and parallel evolution of primary lung cancers and their metastases revealed by molecular dissection of cancer cells.

scientific article published in January 2007

Clonality and heterogeneity of pulmonary blastoma from the viewpoint of genetic alterations: a case report

scientific article published on 9 March 2007

Combination of protein coding and noncoding gene expression as a robust prognostic classifier in stage I lung adenocarcinoma.

scientific article published on 2 May 2013

Combinatory use of distinct single-cell RNA-seq analytical platforms reveals the heterogeneous transcriptome response.

scientific article published on 22 February 2018

Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium

scientific article published on 3 October 2017

Comparisons between Mouse and Human Studies Will Help the Prevention, Diagnosis, and Treatment of the Deadliest Type of Lung Cancer

scientific article published on 01 April 2015

Comprehensive genomic profiles of small cell lung cancer

scientific article published on 13 July 2015

Comprehensive histologic analysis of ALK-rearranged lung carcinomas

scientific article

Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials

scientific article published on 16 November 2016

Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma.

scientific article published on 3 February 2012

Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese

scientific article

Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility.

scientific article published in August 2002

Contribution of the TP53, OGG1, CHRNA3, and HLA-DQA1 Genes to the Risk for Lung Squamous Cell Carcinoma ⬇️

scientific article published on April 1, 2011

Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cells

scientific article published on June 2004

Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor

scientific article published on 3 July 2013

DNA hypermethylation of the ZNF132 gene participates in the clinicopathological aggressiveness of "pan-negative"-type lung adenocarcinomas

scientific article published on 06 November 2020

DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma

scientific article published on 27 March 2013

Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrations

scientific journal article

Detectability of druggable gene fusions by amplicon-based next generation sequencing in LC-SCRUM-Japan

scientific article

Development of lung adenocarcinomas with exclusive dependence on oncogene fusions.

scientific article

Development of nationwide genomic screening project (LC-SCRUM-Japan) contributing to the establishment of precision medicine in Japan

Development of targeted therapy and immunotherapy for treatment of small cell lung cancer.

scientific article

Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo

scientific article published on 8 April 2004

Down-regulation of TCF8 is involved in the leukemogenesis of adult T-cell leukemia/lymphoma

scientific article published on 8 May 2008

Druggable oncogene fusions in invasive mucinous lung adenocarcinoma.

scientific article published on 11 April 2014

Efficacy of glutathione inhibitors for the treatment of ARID1A-deficient diffuse-type gastric cancers

scientific article published on 22 November 2019

Electronic microarray technique for detection of nine base substitutions including single-nucleotide polymorphisms in the human OGG1 gene.

scientific article published on August 2004

Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer

scientific article published on 11 September 2019

Endometrial cancer arising after complete remission of uterine malignant lymphoma: A case report and mutation analysis

scientific article published on 27 February 2019

Epidermal growth factor receptor mutation is associated with longer local control after definitive chemoradiotherapy in patients with stage III nonsquamous non-small-cell lung cancer.

scientific article published on 13 October 2014

Epidermal growth factor receptor tyrosine kinase defines critical prognostic genes of stage I lung adenocarcinoma

scientific article

Epigenetic clustering of lung adenocarcinomas based on DNA methylation profiles in adjacent lung tissue: Its correlation with smoking history and chronic obstructive pulmonary disease

scientific article

Essential Factors for Incompatible DNA End Joining at Chromosomal DNA Double Strand Breaks In Vivo ⬇️

scientific article published on December 14, 2011

Evaluating Clinical Genome Sequence Analysis by Watson for Genomics

scientific article published on 09 November 2018

Evaluation and application of RNA-Seq by MinION

scientific article published on 01 February 2019

Evaluation of a whole-genome amplification method based on adaptor-ligation PCR of randomly sheared genomic DNA.

scientific article published on October 2003

Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing

scientific article published on 11 April 2015

Feasibility and utility of a panel testing for 114 cancer-associated genes in a clinical setting: A hospital-based study

article

Frequent BRAF or EGFR Mutations in Ciliated Muconodular Papillary Tumors of the Lung

scientific article published on 22 December 2015

Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines

scientific article

Frequent EGFR mutations in brain metastases of lung adenocarcinoma

scientific article published in September 2006

Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma

scientific article published in May 2006

Frequent amplification of receptor tyrosine kinase genes in welldifferentiated/ dedifferentiated liposarcoma

scientific article published on 14 January 2017

Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas

scientific article published on March 2002

GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.

scientific article published on 17 November 2016

Garcinol, a Histone Acetyltransferase Inhibitor, Radiosensitizes Cancer Cells by Inhibiting Non-Homologous End Joining ⬇️

scientific article published on March 13, 2012

Gene aberration profile of tumors of adolescent and young adult females.

scientific article published on 29 December 2017

Gene aberrations for precision medicine against lung adenocarcinoma

scientific article

Gene expression classifier for prognosis of early-stage squamous cell carcinoma of the lung

scientific article published in February 2016

Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: a single-institutional methylome analysis using 1007 tissue specimens

scientific article published on 09 January 2017

Genetic alterations responsible for metastatic phenotypes of lung cancer cells

scientific article published on January 1, 2003

Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer

scientific article

Genetic basis for susceptibility to lung cancer: Recent progress and future directions

scientific article published on January 2010

Genetic determinants of lung cancer prognosis in never smokers: A pooled analysis in the International Lung Cancer Consortium

scientific article published on 22 July 2020

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia

scientific article published on 29 December 2014

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

scientific journal article

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer

scientific article published on 28 May 2013

Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer.

scientific article published on 12 September 2016

Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patients

scientific article published on 19 November 2019

Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2

scientific article published on 01 March 2018

Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation

scientific article published on 18 April 2016

HER2 gene mutations in non-small cell lung carcinomas: concurrence with Her2 gene amplification and Her2 protein expression and phosphorylation

scientific article

Heterogeneity of ARID1A expression in gastric cancer may affect patient survival and therapeutic efficacy

scientific article published on 06 May 2020

High-grade glioneuronal tumor with an ARHGEF2-NTRK1 fusion gene

scientific article published on 22 April 2019

Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer.

scientific article

Homozygous deletion scanning of the lung cancer genome at a 100-kb resolution

scientific article published on November 2007

Identification of D19S246 as a novel lung adenocarcinoma susceptibility locus by genome survey with 10-cM resolution microsatellite markers ⬇️

scientific article published on April 1, 2003

Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer

scientific article

Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo

scientific article published on 12 May 2013

Identification of a novel KLC1-ROS1 fusion in a case of pediatric low-grade localized glioma

scientific article published on 22 October 2018

Identification of a novel therapeutic target in driver-negative non-small cell lung cancer

Identification of candidate responders for anti-PD-L1/PD-1 immunotherapy, Rova-T therapy, or EZH2 inhibitory therapy in small-cell lung cancer

scientific article published on 12 December 2017

Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer

scientific article

Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas

scientific article published on 11 November 2011

Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo

scientific article

Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines

scientific article published on 21 March 2018

Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers.

scientific article

Impact of KRAS mutation on response and outcome of patients with stage III non-squamous non-small cell lung cancer

scientific article

Implementation of "Clinical Sequencing" in Cancer Genome Medicine in Japan

scientific article published on 29 December 2017

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Inactivating mutations in SWI/SNF chromatin remodeling genes in human cancer

scientific article published on 30 July 2013

Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes.

scientific article published on 8 January 2010

Infrequent mutations of the activating transcription factor-2 gene in human lung cancer, neuroblastoma and breast cancer.

scientific article

Involvement of Ku80 in microhomology-mediated end joining for DNA double-strand breaks in vivo

scientific article published on 22 January 2007

Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells

scientific article

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

scientific article published on 24 July 2015

KIF5B-RET fusions in lung adenocarcinoma.

scientific article published on 12 February 2012

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

scientific article published on 08 June 2020

Localization of a human lung adenocarcinoma susceptibility locus, possibly syntenic to the mouse Pas1 locus, in the vicinity of the D12S1034 locus on chromosome 12p11.2-p12.1.

scientific article published on 01 July 2002

Long-read sequencing for non-small-cell lung cancer genomes

scientific article published on 04 September 2020

Long-term expansion of alveolar stem cells derived from human iPS cells in organoids.

scientific article published on 2 October 2017

Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d

scientific article published on 17 December 2020

Lung cancer genomics and its application to prevention, diagnosis and treatment of lung cancer

scientific article published on 01 August 2010

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1

scientific article

MYC amplification as a prognostic marker of early-stage lung adenocarcinoma identified by whole genome copy number analysis.

scientific article

MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells

scientific article published on 14 October 2016

MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer

scientific article

Medical treatment involving investigational drugs and genetic profile of thymic carcinoma.

scientific article

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

scientific article

Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin.

scientific article published on 16 January 2017

Molecular Process Producing Oncogene Fusion in Lung Cancer Cells by Illegitimate Repair of DNA Double-Strand Breaks

scientific article

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare mutations

scientific article published on 01 May 2019

Molecular footprints of human lung cancer progression

scientific article published on March 2004

Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma.

scientific article published in May 2014

Molecular processes of chromosome 9p21 deletions causing inactivation of the p16 tumor suppressor gene in human cancer: deduction from structural analysis of breakpoints for deletions

scientific article published on 22 August 2006

Molecular processes of chromosome 9p21 deletions in human cancers

scientific article

Mouse Model for ROS1-Rearranged Lung Cancer ⬇️

scientific article published on February 13, 2013

Multiplex Diagnosis of Oncogenic Fusion and MET Exon Skipping by Molecular Counting Using Formalin-Fixed Paraffin Embedded Lung Adenocarcinoma Tissues.

scientific article published on 19 December 2015

Mutations and deletions of the CBP gene in human lung cancer.

scientific article published on January 2005

N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells ⬇️

scientific article published on August 8, 2011

NEK9-dependent proliferation of cancer cells lacking functional p53

scientific article

Nationwide genomic screening network for the development of novel targeted therapies in advanced non-small cell lung cancer (LC-SCRUM-Japan)

Nationwide genomic screening network for the development of targeted therapies in NSCLC (LC-SCRUM-Japan)

scientific article

Next-Generation Sequencer Analysis of Pulmonary Pleomorphic Carcinoma With a CD74-ROS1 Fusion Successfully Treated With Crizotinib

scientific article published on 01 May 2019

Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell-like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit.

scientific article published on 2 February 2016

Pathogenetic and biologic significance of TP14ARF alterations in nonsmall cell lung carcinoma

scientific article published on February 2003

Phasing analysis of lung cancer genomes using a long read sequencer

scientific article published in 2022

Picoliter-Droplet Digital Polymerase Chain Reaction-Based Analysis of Cell-Free Plasma DNA to Assess EGFR Mutations in Lung Adenocarcinoma That Confer Resistance to Tyrosine-Kinase Inhibitors

scientific article published on 14 January 2016

Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system

scientific article

Precision medicine for ovarian clear cell carcinoma based on gene alterations

scientific article published on 04 February 2020

Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma

scientific article published on 19 May 2010

Prevalent involvement of illegitimate V(D)J recombination in chromosome 9p21 deletions in lymphoid leukemia

scientific article published on 12 September 2002

Primary adenocarcinoma of the trachea revealing a mucinous bronchial gland cell origin

scientific article published on 06 March 2018

Probing the chromosome 9p21 region susceptible to DNA double-strand breaks in human cells in vivo by restriction enzyme transfer.

scientific article published in September 2005

Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing

scientific article

Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer.

scientific article

Proposal for a synthetic lethality therapy using the paralog dependence of cancer cells--response

scientific article published on 18 August 2014

RET fusion gene: translation to personalized lung cancer therapy

scientific article

REToma: a cancer subtype with a shared driver oncogene

scientific article published on 11 November 2019

ROS1-rearranged lung cancer: a clinicopathologic and molecular study of 15 surgical cases

scientific article published in April 2013

Radiopathologic correlation of collision lung cancer with ground-glass opacity

scientific article published on 11 November 2018

Rapid assessment of two major repair activities against DNA double-strand breaks in vertebrate cells

scientific article published on 17 November 2005

Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer

scientific article

Reduced levels of ATF-2 predispose mice to mammary tumors.

scientific article published on 22 December 2006

Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels.

scientific article published on 09 April 2013

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability

scientific article (publication date: May 2014)

Sequencing and phasing cancer mutations in lung cancers using a long-read portable sequencer

scientific article published on 27 June 2017

Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors

scientific article published on 04 December 2018

Significantly mutated genes and regulatory pathways in SCLC-a meta-analysis

scientific article

Simple prediction model for homologous recombination deficiency in breast cancers in adolescents and young adults

scientific article published on 03 June 2020

Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment

scientific article published on 3 April 2015

Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry-A Meta-Analysis of Chromosome 15q25

article

Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.

scientific article

Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.

scientific article

Subependymal giant cell astrocytoma harboring a PRRC2B-ALK fusion: A case report

scientific article published on 10 September 2019

Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo

scientific article

TSPAN12 is a critical factor for cancer-fibroblast cell contact-mediated cancer invasion

scientific article

TSPAN2 is involved in cell invasion and motility during lung cancer progression.

scientific article published on 13 April 2014

Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression

scientific article published on 24 November 2015

Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers

scientific article published on 24 January 2019

The ACF1 Complex Is Required for DNA Double-Strand Break Repair in Human Cells ⬇️

scientific article published on December 22, 2010

The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt

scientific article

The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells

scientific article published on 11 June 2015

The Lung Cancer Genomic Screening Project for Individualized Medicine in Japan (LC-SCRUM-Japan): Screening for RET and ROS1 fusions in advanced EGFR mutation-negative nonsquamous lung cancer and development of molecular targeted therapy

The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: a retrospective analysis of three cohorts.

scientific article

The expression of four genes as a prognostic classifier for stage I lung adenocarcinoma in 12 independent cohorts

scientific article

The first case of SMARCB1 (INI1) - deficient squamous cell carcinoma of the pleura: a case report

scientific article published on 7 April 2018

The genomic and epigenomic landscape in thymic carcinoma

scientific article published on 01 October 2017

The intratumoral distribution influences the prognostic impact of CD68- and CD204-positive macrophages in non-small cell lung cancer

The low expression of miR-451 predicts a worse prognosis in non-small cell lung cancer cases

scientific article

The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients

scientific article published on 04 December 2020

The usefulness of mutation-specific antibodies in detecting epidermal growth factor receptor mutations and in predicting response to tyrosine kinase inhibitor therapy in lung adenocarcinoma ⬇️

scientific article published on December 3, 2010

Therapeutic preferability of gemcitabine for ARID1A-deficient ovarian clear cell carcinoma

scientific article published on 08 October 2019

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis

scientific article

Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy

scientific article published on 9 March 2017

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

scientific article published on 12 July 2019

Utility of Assessing the Number of Mutated KRAS, CDKN2A, TP53, and SMAD4 Genes Using a Targeted Deep Sequencing Assay as a Prognostic Biomarker for Pancreatic Cancer.

scientific article

Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants

scientific article published on 01 January 2021

Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial

scientific article published on 4 November 2016

Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas

scientific article published on 3 February 2009

Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease

scientific article published on 04 October 2019

[Challenge of gene-based personalized lung cancer medicine]

scientific article published on 01 August 2015

[Genetic factors involved in cancer susceptibility]

scientific article published on 01 July 2002

[Wnt signaling abnormalities in human lung cancer]

scientific article published on 01 May 2002

c-MET/Phospho-MET Protein Expression and MET Gene Copy Number in Non-small Cell Lung Carcinomas ⬇️

scientific article published on February 1, 2012

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