List of works by M Gordon Joyce

A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

scientific article (preprint)

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

scientific article (publication date: 2015)

A SARS-CoV-2 vaccine candidate would likely match all currently circulating strains

scientific article published on 28 April 2020

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants

scientific article published on 31 August 2020

A rational approach to heavy-atom derivative screening

scientific article

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

scientific article published on 12 March 2004

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

scientific article published on 26 October 2017

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 01 June 2019

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

scientific article

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

scientific article published on 3 June 2015

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

scientific article published on September 2017

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

scientific article published in October 2014

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

article

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

scientific article

Computational prediction of N-linked glycosylation incorporating structural properties and patterns

scientific article

Conformational Mobility in the Active Site of a Heme Peroxidase

scientific article published in Journal of Biological Chemistry

Correction: Trinh, H.V., et al. Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort. Cells 2019, 8, 365

scientific article published on 06 June 2019

CprK crystal structures reveal mechanism for transcriptional control of halorespiration

scientific article

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

scientific article published on 11 December 2019

Crystal structure of human natural cytotoxicity receptor NKp30 and identification of its ligand binding site

scientific article

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

scientific article

DC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cells

scientific article

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages

scientific article published on 26 February 2019

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

scientific article

Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.

scientific article

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

scientific article published on 13 August 2014

Evaluation of candidate vaccine approaches for MERS-CoV.

scientific article published on 28 July 2015

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

scientific article

Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.

scientific article published on 12 March 2004

Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer

scientific article published on 22 September 2010

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

scientific article

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

article

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

scientific article published on 30 January 2020

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

scientific article

Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort.

scientific article published on 19 April 2019

Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

scientific article published on 01 September 2020

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

scientific article published on November 2016

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells

scientific article published on 09 April 2019

Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on MERS-CoV Spike to avoid neutralization escape

scientific article published on 7 March 2018

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

scientific article published on September 2016

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis

scientific article published on 12 September 2019

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

scientific article published on 29 October 2021

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

scientific article

Maturation Pathways for the Broad and Potent Antibody 10E8 Using a Combination of Next Generation Sequencing, Bioinformatics and Functional Analysis

scientific article published in October 2014

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

scientific article

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

scientific article published on March 2017

Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

scientific article

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

scientific article

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 11 February 2019

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

scientific article

Need for Speed: From Human SARS-CoV-2 Samples to Protective and Efficacious Antibodies in Weeks

scientific article published on 01 July 2020

Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous andvirion-associated SERINC5

scientific article published on 01 January 2020

Optimization of a Clade A Env Outer Domain for Enhanced Binding to Germlines of Diverse VRC01 Class Antibodies

Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04

scientific article

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

scientific article published on 03 February 2020

Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans

scientific article published on July 2017

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

scientific article

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine

scientific article published on 01 April 2019

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

scientific article published on March 2017

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

scientific article published on April 2017

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

scientific article published on 12 August 2015

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies

scientific article

Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

scientific article

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

scientific article published on 4 March 2015

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

scientific article published in December 2017

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

scientific article

Strategies to guide the antibody affinity maturation process

scientific article published on 24 April 2015

Structural Determinants of Integrin Binding to the Talin Rod

scientific article

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

scientific article

Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

scientific article published on 04 June 2021

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

scientific article

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

scientific article

Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)

article

Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain)

article

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

scientific article

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

scientific article published on 8 March 2017

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

scientific article

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

scientific article

Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection

scientific article published on 18 March 2015

The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors

scientific article

The structural basis of ligand recognition by natural killer cell receptors

scientific article

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

scientific article

Towards a rational approach for heavy-atom derivative screening in protein crystallography.

scientific article

Transient Protein Expression Facilitates X-ray Structural Studies of HIV-1.

scientific article

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

scientific article

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

scientific article published in October 2014

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

scientific article published in December 2017

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

scientific article

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

scientific article published on May 2017

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