List of works - Florian Klein

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

scientific article published on 30 October 2015

A mouse model for HIV-1 entry

scientific article

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

scientific article published on 27 April 2016

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

scientific article

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

scientific article

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

scientific article

Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice

scientific article

Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity

scientific article published on 03 February 2020

Combination therapy with anti-HIV-1 antibodies maintains viral suppression

scientific article published in Nature

Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues

scientific article

Corrigendum: Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

scientific article published on 23 March 2016

Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia

scientific article published on 18 September 2020

Early antibody therapy can induce long-lasting immunity to SHIV

scientific article

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

scientific article

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

scientific article

HIV-1 integration landscape during latent and active infection

scientific article

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

scientific article published on 16 September 2013

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

scientific article

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

scientific article

Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection

scientific article

Lactobacilli Expressing Broadly Neutralizing Nanobodies against HIV-1 as Potential Vectors for HIV-1 Prophylaxis?

scientific article published on 13 December 2020

Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site

scientific article

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

scientific article

Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV

scientific article published on 07 October 2019

RETRACTED: Silencing of B cell receptor signals in human naive B cells

retracted scientific article

RNAemia Corresponds to Disease Severity and Antibody Response in Hospitalized COVID-19 Patients

scientific article published on 18 September 2020

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

scientific article

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody

scientific article published on 30 January 2020

Retraction

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

scientific article

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

scientific article

T lymphoid differentiation in human bone marrow ⬇️

scientific article published on May 8, 2003

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

scientific article

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

scientific article published on 08 April 2015

List of works by Florian Klein

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

A mouse model for HIV-1 entry

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice

Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity

Combination therapy with anti-HIV-1 antibodies maintains viral suppression

Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues

Corrigendum: Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia

Early antibody therapy can induce long-lasting immunity to SHIV

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

HIV-1 integration landscape during latent and active infection

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection

Lactobacilli Expressing Broadly Neutralizing Nanobodies against HIV-1 as Potential Vectors for HIV-1 Prophylaxis?

Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV

RETRACTED: Silencing of B cell receptor signals in human naive B cells

RNAemia Corresponds to Disease Severity and Antibody Response in Hospitalized COVID-19 Patients

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody

Retraction

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

T lymphoid differentiation in human bone marrow ⬇️

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.