Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Gianpietro Dotti

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

scientific article published on 10 August 2018

A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

scientific article published on 23 June 2005

Activation of Wnt signaling arrests effector differentiation in human peripheral and cord blood-derived T lymphocytes

scientific article published on 19 October 2011

Adoptive T-cell immunotherapy of chronic lymphocytic leukaemia

scientific article published on September 2008

Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience

scientific article

Allorestricted cytotoxic T cells specific for human CD45 show potent antileukemic activity

scientific article published on 12 September 2002

An inducible caspase 9 safety switch for T-cell therapy

scientific article published on 22 February 2005

An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies

scientific article published on June 2010

Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma

scientific article published on 23 July 2020

Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis

scientific article published on 12 October 2020

Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

scientific article published on 7 October 2011

Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor

scientific article

Bortezomib sensitizes non-small cell lung cancer to mesenchymal stromal cell-delivered inducible caspase-9-mediated cytotoxicity

scientific article

Bystander Transfer of Functional Human CD40 Ligand from Gene-Modified Fibroblasts to B-Chronic Lymphocytic Leukemia Cells ⬇️

scientific article published on April 10, 2003

CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma

scientific article published on 8 June 2017

CARs on track in the clinic

scientific article

CD19-CAR trials

scientific article published on March 2014

CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients

scientific article

Cellular immunity to Epstein-Barr virus in liver transplant recipients treated with rituximab for post-transplant lymphoproliferative disease

scientific article

Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes

scientific article published on 14 August 2017

Clinical responses with T lymphocytes targeting malignancy-associated κ light chains

scientific article published on 06 June 2016

Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch

scientific article

Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

scientific article

Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes.

scientific article

Comparison of two CD40-ligand/interleukin-2 vaccines in patients with chronic lymphocytic leukemia ⬇️

scientific article published on July 12, 2011

Cryo-shocked cancer cells for targeted drug delivery and vaccination

scientific article published on 09 December 2020

Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia

scientific article

Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation

scientific article

Design and development of therapies using chimeric antigen receptor-expressing T cells

scientific article published on January 2014

Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis

scientific article published on 13 May 2021

Early transduction produces highly functional chimeric antigen receptor-modified virus-specific T-cells with central memory markers: a Production Assistant for Cell Therapy (PACT) translational application

scientific article

Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma

scientific article published on 23 September 2020

Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease

scientific article

Ex vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2Rγ(null) mice.

scientific article

Fibrin gel enhances the antitumor effects of chimeric antigen receptor T cells in glioblastoma

scientific article published on 06 October 2021

Fifteen years of gene therapy based on chimeric antigen receptors: "are we nearly there yet?".

scientific article

Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment

scientific article

Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes

scientific article published on 14 May 2009

GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade

scientific article published on 29 March 2016

Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)

scientific article published on 16 September 2009

Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7.

scientific article published on 3 March 2009

HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial

scientific article published on 20 April 2017

High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells

scientific article

Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma

scientific article published on 23 March 2015

Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis.

scientific article published on 15 February 2005

Immunotherapy of human cancers using gene modified T lymphocytes

scientific article

Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells

scientific article published on 8 September 2009

In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas

scientific article published on 13 September 2018

Inducible apoptosis as a safety switch for adoptive cell therapy

scientific article (publication date: 3 November 2011)

Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation

scientific article published on 29 May 2007

Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation

scientific article published on 14 May 2015

Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes

scientific article

Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study

scientific article published on 12 September 2013

Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets

scientific article published on 26 April 2021

Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: implications for adoptive T cell-based therapies for lymphoma

scientific article published on 13 November 2012

Interleukin-23 engineering improves CAR T cell function in solid tumors

scientific article published on 03 February 2020

Interleukin-7 Mediates Selective Expansion of Tumor-redirected Cytotoxic T Lymphocytes (CTLs) without Enhancement of Regulatory T-cell Inhibition ⬇️

scientific article published on October 4, 2013

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

scientific article

Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers.

scientific article published on 18 June 2015

Molecular transfer of CD40 and OX40 ligands to leukemic human B cells induces expansion of autologous tumor-reactive cytotoxic T lymphocytes

scientific article published on 9 November 2004

Noninvasive bioluminescent imaging demonstrates long-term multilineage engraftment of ex vivo-expanded CD34-selected umbilical cord blood cells

scientific article published on August 2009

Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells

scientific article published on 3 July 2003

Regression of experimental medulloblastoma following transfer of HER2-specific T cells

scientific article published in June 2007

Repetitive noninvasive monitoring of HSV1-tk-expressing T cells intravenously infused into nonhuman primates using positron emission tomography and computed tomography with 18F-FEAU

scientific article

Responses to human CD40 ligand/human interleukin-2 autologous cell vaccine in patients with B-cell chronic lymphocytic leukemia

scientific article published on October 2005

Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease

scientific article published on 14 December 2012

Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression

scientific article published on 18 November 2009

Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation

scientific article published on 28 December 2015

Survivin-specific T cell receptor targets tumor but not T cells

scientific article

T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.

scientific article published on 17 April 2009

T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells

scientific article published on 22 August 2006

T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor-Expressing T Cells

scientific article published on 26 September 2019

Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

scientific article published on 18 July 2016

Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

scientific article published on 02 July 2019

Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration

scientific article published on 20 April 2022

Transgenic expression of CD40 ligand produces an in vivo antitumor immune response against both CD40(+) and CD40(-) plasmacytoma cells

scientific article

Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs

scientific article published on 4 May 2015

Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma

scientific article published on 15 July 2020

Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma

scientific article published on 9 January 2018

Paulina is supported by:

About Paulina

Help