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List of works by Douglas T Golenbock

100 NF-κB Activation by Mal/Tirap is Regulated by Caspase-1

scholarly article by Sinead M. Miggin et al published July 2007 in Cytokine

3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1β interferes with mature IL-1β signaling

scientific article

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.

scientific article published on February 2016

A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection.

scientific article published on 22 June 2016

A Leptospira interrogans enzyme with similarity to yeast Ste14p that methylates the 1-phosphate group of lipid A.

scientific article

A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae

scientific article published on 15 January 2016

A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling

scientific article

A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2.

scientific article

A guiding map for inflammation

scientific article published on July 2017

A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia

scientific article published on 01 July 2006

A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization

scientific article published on 30 September 2002

Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii

scientific article

Activation of the NLRP3 inflammasome by group B streptococci

scientific article published on 16 January 2012

Activation of the NLRP3 inflammasome in microglia: The role of ceramide

scientific article published on 23 September 2017

Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation

scientific article published in February 2005

Adjuvants and their signaling pathways: beyond TLRs

scientific article published on 01 December 2003

Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist

scientific article published on 25 October 2009

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.

scientific article published in June 2012

Analysis of the activity to induce toll-like receptor (TLR)2- and TLR4-mediated stimulation of supragingival plaque

scientific article published on 01 May 2008

Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens

scientific article

Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress

scientific article

Author Correction: A guiding map for inflammation

scientific article published on 07 December 2020

Author Correction: Caspase-8 mediates inflammation and disease in rodent malaria

scientific article published on 03 November 2020

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

scientific article published on January 12, 2011

Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs

scientific article published on February 2008

Biological activities of Bacteroides forsythus lipoproteins and their possible pathological roles in periodontal disease.

scientific article published on March 2004

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

scientific journal article

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

scientific article

CXCR3 chemokine receptor contributes to specific CD8+ T cell activation by pDC during infection with intracellular pathogens

scientific article published on 23 June 2020

Caspase-8 mediates inflammation and disease in rodent malaria

scientific article published on 14 September 2020

Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis

scientific article published in February 2008

Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs

scientific article published on January 1, 2003

Cell activation by Toll-like receptors: role of LBP and CD14.

scientific article

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

scientific article published on 01 October 2002

Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll Like Receptor 9 Signaling

scientific article published on 22 August 2020

Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.

scholarly article

Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice

scientific article published on 3 January 2013

Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection

scientific article published on December 2005

Control of the innate immune response by the mevalonate pathway.

scientific article published on 06 June 2016

Cutting Edge: Plasmodium falciparum Induces Trained Innate Immunity.

scientific article published on 12 January 2018

Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.

scientific article published on February 2002

Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4

scientific article published on 01 June 2002

Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.

scientific article published on 6 December 2017

DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.

scientific article

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

scientific article

Defective pro-IL-1β responses in macrophages from aged mice

scientific article published on December 11, 2012

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.

scientific article published on 21 September 2017

Dried Whole Plant Artemisia annua as an Antimalarial Therapy

scientific article published on December 20, 2012

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria

scientific article

Dual role of TLR2 and myeloid differentiation factor 88 in a mouse model of invasive group B streptococcal disease

scientific article published in May 2004

Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells

scientific article (publication date: November 2002)

Endotoxin recognition and signal transduction by the TLR4/MD2-complex

scientific article

Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome.

scientific article

Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi

scientific article published in November 2004

Failure of TLR4-driven NF-kappa B activation to stimulate virus replication in models of HIV type 1 activation

scientific article published on November 2007

Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition

scientific article published on November 2006

Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions

scientific article

Gingipains inactivate a cell surface ligand on Porphyromonas gingivalis that induces TLR2-and TLR4-independent signaling

scientific article published on January 2006

Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production

scientific article published on July 2016

HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

scientific article published on August 2006

Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity

scientific article published on February 2004

Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent

scientific article

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.

scientific article published on 18 January 2012

Hemolysis-induced lethality involves inflammasome activation by heme

scientific article

Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation

scientific article

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

scientific article

Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent

scientific article published on 01 August 2005

Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.

scientific article

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

scientific article published on 09 April 2020

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

scientific article

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

scientific article

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

scientific article (publication date: May 2003)

IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients

scientific article

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

scientific article

Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

scientific article published on 04 June 2020

Immunology. The shape of things to come

scientific article published on 01 June 2007

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling

scientific article

Increased survival in B-cell-deficient mice during experimental cerebral malaria suggests a role for circulating immune complexes.

scientific article

Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14

scientific article published on 01 May 2002

Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice

scientific article published on 02 February 2009

Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice

scientific article published on 20 August 2018

Inflammasomes: too big to miss

scientific article

Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins

scientific article published on 4 January 2013

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1

article

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1.

scientific article published on January 2005

Innate immune recognition of Yersinia pseudotuberculosis type III secretion

scientific article

Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome

scientific article

Innate immune recognition of lipopolysaccharide by endothelial cells

scientific article

Innate immune responses to Rhodococcus equi

scientific article published in August 2004

Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

scientific article published on January 2007

Innate immunity in Alzheimer's disease

scientific article

Innate sensing of malaria parasites

scientific article

Interferon-γ and Granulocyte/Monocyte Colony-stimulating Factor Production by Natural Killer Cells Involves Different Signaling Pathways and the Adaptor Stimulator of Interferon Genes (STING)

scientific article published on February 26, 2013

Introduction: Toll receptors come of age.

scientific article published in December 2004

Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin

scientific article published on 21 November 2014

Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers

scientific article published on 27 June 2002

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

scientific article

LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia

scientific article published on 27 September 2004

LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux

scientific article published on 27 October 2015

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

scientific article published on 17 June 2007

Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice

scientific article published on December 2003

Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection

scientific article published on 01 August 2005

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

scientific article (publication date: 6 December 2002)

Lipopolysaccharides from Periodontopathic BacteriaPorphyromonas gingivalisandCapnocytophaga ochraceaAre Antagonists for Human Toll-Like Receptor 4

scientific article published on January 1, 2002

Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis.

scientific article published in May 2008

Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor

scientific article

Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses.

scientific article published in February 2008

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction

scientific article (publication date: 28 November 2003)

MD-2 expression is not required for cell surface targeting of Toll-like receptor 4 (TLR4).

scientific article published on 31 August 2006

MD-2 residues tyrosine 42, arginine 69, aspartic acid 122, and leucine 125 provide species specificity for lipid IVA.

scientific article

MD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation

scientific article

MD-2.

scientific article published on 18 July 2006

MUC1 mucin is a negative regulator of toll-like receptor signaling

scientific article published on 13 December 2007

Macrophages recognize streptococci through bacterial single‐stranded RNA

scientific article published on December 17, 2010

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization

scientific article

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

scholarly article

Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.

scholarly article

Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.

scientific article published on 16 January 2014

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide

scientific article

Mechanisms of TLR9 activation

scientific article

Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation

scientific article published in June 2002

Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling

scientific journal article

Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production

scientific article

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease

scientific article published in December 2017

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway

scientific article

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

scientific article published on 10 July 2009

MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3.

scientific article published on 28 August 2009

MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection

scientific article

MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

scientific article

MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.

scientific article published on 21 March 2007

NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

scholarly article

NLRP3 inflammasome activation drives tau pathology

scientific article published on 20 November 2019

NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

scientific article published on August 29, 2012

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

scientific article published on December 19, 2012

NO is a macrophage autonomous modifier of the cytokine response to streptococcal single-stranded RNA

scientific article published on 19 December 2011

Natural Loss-of-function Mutation of Myeloid Differentiation Protein 88 Disrupts Its Ability to Form Myddosomes

scientific article published on February 16, 2011

Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

scientific article

Neuroinflammation in Alzheimer's disease

scientific article (publication date: April 2015)

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice

scientific article published in October 2002

Non–Mannose-capped Lipoarabinomannan Induces Lung Inflammation via Toll-like Receptor 2

scientific article published on 24 September 2004

Of mice and man: TLR11 (finally) finds profilin

scientific article

Peptidoglycan recognition by the Drosophila Imd pathway

scientific article published in January 2005

Peptidoglycan recognition by the Drosophila Imd pathway

Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling

scientific article published on 18 January 2008

Phagocytosis, innate immunity, and host-pathogen specificity

scientific article published on January 2004

Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

scientific article published on November 2005

Plasmodium falciparum infection causes proinflammatory priming of human TLR responses

scientific article published in July 2007

Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR

scientific article published on 26 September 2019

Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling

scientific article

Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo

scientific article published on March 2006

RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages.

scientific article

Receptor “cross talk” in innate immunity

scientific article published on October 1, 2003

Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2.

scientific article published on 30 March 2007

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

scholarly article

Recombinant Ov-ASP-1, a Th1-biased protein adjuvant derived from the helminth Onchocerca volvulus, can directly bind and activate antigen-presenting cells

scientific article published in April 2009

Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.

scientific article

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

scientific article published on 14 March 2004

Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6

scientific journal article

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response

scientific article

Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi

scientific article

Role of lipoteichoic acid in the phagocyte response to group B streptococcus.

scientific article

Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus

scientific article published on 30 March 2009

SS4-6 MAL/TIRAP negatively regulates Toll-like receptor 3-mediated IFN-β production

Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.

scientific article

Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome

scientific article published on 30 July 2019

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway

scientific article

TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.

scientific article published on December 2008

TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

scientific article published on 11 April 2009

TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia

scientific article (publication date: 9 April 2010)

TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like

scientific article published on 19 October 2010

TLR9 and the recognition of self and non-self nucleic acids

scientific article published on 01 October 2006

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

scientific article published on 11 January 2004

TRIF signaling is essential for TLR4-driven IgE class switching

scientific article

Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria

article published in the Proceedings of the National Academy of Sciences of the United States of America

The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus.

scientific article

The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria

scientific article

The LPS receptor generates inflammatory signals from the cell surface

scientific article published on January 2003

The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses

scientific article published on 20 February 2019

The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2

scientific article published on 18 March 2019

The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism

scientific article published on 14 July 2003

The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease

scientific article

The differential impact of disulfide bonds and N-linked glycosylation on the stability and function of CD14.

scientific article published on 5 December 2007

The genome of Anopheles darlingi, the main neotropical malaria vector

scientific article published on 12 June 2013

The history of Toll-like receptors - redefining innate immunity.

scientific article published on 17 May 2013

The immunology of Plasmodium vivax malaria

scientific article published on 23 October 2019

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

scientific article published on 14 September 2004

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling

scientific article

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

scientific article

The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice

scientific journal article

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

scientific article

Toll-Like Receptors Participate in Macrophage Activation and Intracellular Control of Leishmania (Viannia) panamensis

scientific article published on April 25, 2011

Toll-like Receptor (TLR) 2 Mediates Inflammatory Responses to Oligomerized RrgA Pneumococcal Pilus Type 1 Protein

scientific article published on December 11, 2012

Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus

scientific article published on 8 August 2002

Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.

scientific article published on 4 October 2005

Toll-like receptor 2 mediates persistent chemokine release by Chlamydia pneumoniae-infected vascular smooth muscle cells

scientific article published on 22 September 2005

Toll-like receptor-dependent discrimination of streptococci

scientific article published on January 2006

Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling

scientific journal article

Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance

scientific article

Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.

scientific article

UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major

scientific article published on 16 January 2013

UNC93B1 mediates host resistance to infection with Toxoplasma gondii

scientific article

Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule

scientific article published on 27 August 2010

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction

scientific article

c-Jun kinase is a critical signaling molecule in a neonatal model of group B streptococcal sepsis

scientific article published on March 2006

miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).

scientific article published on 16 February 2017