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List of works by Takashi Tokino

Aberrant methylation and histone deacetylation associated with silencing of SLC5A8 in gastric cancer

scientific article published on May 2004

Activation of the ribosomal protein L13 gene in human gastrointestinal cancer.

scientific article

Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2.

scientific article published in April 2003

CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation

scientific article published on 15 February 2012

CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion

scientific article published on 18 September 2012

Corrigendum to "Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer"

scientific article published on 07 August 2019

DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae

scientific article

DNA methyltransferase 1 is essential for initiation of the colon cancers

scientific article

DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling

scholarly article by Kazuya Ishiguro et al published January 2019 in Haematologica

Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment

scientific article published on 17 July 2018

Epigenetic inactivation of CHFR in human tumors

scientific article

Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells.

scientific article

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

scientific article published on 3 August 2007

Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo

scientific article published on 07 June 2021

Genetic analyses of mosaic neurofibromatosis type 1 with giant café-au-lait macule, plexiform neurofibroma and multiple melanocytic nevi

scientific article published on 04 April 2020

Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes

scientific article

Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models

scientific article

Histone deacetylation, but not hypermethylation, modifies class II transactivator and MHC class II gene expression in squamous cell carcinomas

scientific article published on May 2003

IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype

scientific article

Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer

scientific article published on January 2007

Identification of flotillin-2, a major protein on lipid rafts, as a novel target of p53 family members

scientific article

Identification of the osteopontin gene as a direct target of TP53.

scientific article published on March 2002

Induction of tenascin-C by tumor-specific EWS-ETS fusion genes

scientific article

Long non-coding RNA NEAT1 is a transcriptional target of p53 and modulates p53-induced transactivation and tumor-suppressor function.

scientific article published on 14 March 2017

Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.

scientific article published on 17 September 2012

Mutation profiling of uterine cervical cancer patients treated with definitive radiotherapy

scientific article published on 17 September 2020

Pathogenesis of multiple pancreatic cancers involves multicentric carcinogenesis and intrapancreatic metastasis

scientific article published on 15 January 2020

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.

scientific article published on 13 July 2016

Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer

scientific article published on 02 May 2019

Regulation of MHC class II expression in glioma cells by class II transactivator (CIITA).

scientific article published on March 2004

The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer

scientific article

The effect of forced expression of mutated K-RAS gene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy.

scientific article published on 17 June 2016

The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents

scientific article

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