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List of works by Bernd Jilma

"Protocol for a phase 2, randomized, double-blind, placebo-controlled, safety and efficacy study of dutogliptin in combination with filgrastim in early recovery post-myocardial infarction": study protocol for a randomized controlled trial

scientific article published on 26 August 2020

A Novel Diagnostic and Prognostic Score for Abdominal Aortic Aneurysms Based on D-Dimer and a Comprehensive Analysis of Myeloid Cell Parameters

scientific article published on 01 March 2019

A Randomized, First-in-Human, Healthy Volunteer Trial of sutimlimab, a Humanized Antibody for the Specific Inhibition of the Classical Complement Pathway

scientific article published on 13 July 2018

A dose ranging phase I/II trial of the von Willebrand factor inhibiting aptamer ARC1779 in patients with congenital thrombotic thrombocytopenic purpura

scientific article

A model comparing how rapidly transfusion of solvent detergent plasma restores clotting factors versus infusion of albumin-saline

scientific article published on 29 July 2015

A phase III randomized, multicentre, double blind, active controlled trial to compare the efficacy and safety of two different anagrelide formulations in patients with essential thrombocythaemia - the TEAM-ET 2·0 trial

scientific article published on 28 March 2019

A proinflammatory state is detectable in obese children and is accompanied by functional and morphological vascular changes

scientific article published on 14 September 2006

A randomised pilot trial of the anti-von Willebrand factor aptamer ARC1779 in patients with type 2b von Willebrand disease

scientific article

A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity

scientific article published in July 2006

A randomized, double-blind, parallel, single-site pilot trial to compare two different starting doses of methotrexate in methotrexate-naïve adult patients with rheumatoid arthritis

scientific article published on 18 April 2012

A randomized, placebo-controlled phase I study assessing the safety and immunogenicity of a Pseudomonas aeruginosa hybrid outer membrane protein OprF/I vaccine (IC43) in healthy volunteers

scientific article

A short-chain methotrexate polyglutamate as outcome parameter in rheumatoid arthritis patients receiving methotrexate.

scientific article published in March 2012

ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion

scientific article

Abciximab as a bridging strategy to overcome morphine-prasugrel interaction in STEMI patients

scientific article published on July 2016

Absorption kinetics of low-dose chewable aspirin--implications for acute coronary syndromes

scientific article published on 01 January 2015

Acenocoumarol decreases tissue factor-dependent coagulation during systemic inflammation in humans

scientific article

Acetylsalicylic acid in critically ill patients: a cross-sectional and a randomized trial.

scientific article

Acquired von Willebrand factor deficiency caused by LVAD is ADAMTS-13 and platelet dependent

scientific article

Activation of calcium-dependent calmodulin by calcium(II)3(3,5-diisopropylsalicylate)6(H2O)6 decreases thrombin receptor activating peptide-induced P-selectin expression

scientific article published on February 2003

Acute effects of hyperglycaemia on plasma concentration of soluble P-selectin and von Willebrand factor in healthy volunteers -a prospective randomised double blind controlled study

scientific article published on 15 August 2008

Additive effects between platelet concentrates and desmopressin in antagonizing the platelet glycoprotein IIb/IIIa inhibitor eptifibatide

scientific article (publication date: March 2005)

Aerosolized lancovutide in adolescents (≥12 years) and adults with cystic fibrosis - a randomized trial

scientific article published on 01 September 2020

Altered platelet plug formation in hyperthyroidism and hypothyroidism

scientific article published on 08 May 2007

An experimental model to study isolated effects of thrombin in vivo

scientific article

Androgen deprivation decreases prostate specific antigen in the absence of tumor: implications for interpretation of PSA results

scientific article published on 01 March 2014

Angiotensin II for the treatment of vasodilatory shock: enough data to consider angiotensin II safe?

scientific article published on 16 April 2018

Angiotensin receptor blockade decreases markers of vascular inflammation

scientific article published in September 2004

Anti-cardiolipin antibodies and overall survival in a large cohort: preliminary report

scientific article published on 30 March 2006

Anti-von Willebrand factor aptamer ARC1779 for refractory thrombotic thrombocytopenic purpura

scientific article

Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration

scientific article published on 05 September 2020

Asphyxia by Drowning Induces Massive Bleeding Due To Hyperfibrinolytic Disseminated Intravascular Coagulation.

scientific article

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups

scientific article published on 04 November 2019

Assessing the influence of diurnal variations and selective Xa inhibition on whole blood aggregometry.

scientific article published on 7 July 2015

Assessment of platelets and the endothelium in patients presenting with acute coronary syndromes--is there a future?

scientific article published on 01 December 2009

Association between the rs342293 polymorphism and adverse cardiac events in patients undergoing percutaneous coronary intervention

Association of ABO blood group with bleeding severity in patients with bleeding of unknown cause

scientific article published on 01 October 2020

Blockade of GPIIb/IIIa by eptifibatide and tirofiban does not alter tissue factor induced thrombin generation in human endotoxemia

scientific article published on 01 December 2003

Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera from Subjects Dosed with the Anti-C1s Monoclonal Antibody TNT009 - Results from a Randomized First-in-Human Phase 1 Trial.

scientific article

Bridging the Missing Link with Emicizumab: A Bispecific Antibody for Treatment of Hemophilia A

scientific article published on 27 July 2020

Calcium channel blockers reduce the antiplatelet effect of clopidogrel

Calcium-channel blockers reduce the antiplatelet effect of clopidogrel

scientific article

Can Sequential Coagulation Monitoring Predict Major Haemorrhage in Extremely Low Birth Weight Infants?

scientific article published on 04 June 2018

Changes in ADAMTS13 (von-Willebrand-factor-cleaving protease) activity after induced release of von Willebrand factor during acute systemic inflammation

scientific article published on 01 March 2005

Changes in thrombopoiesis and platelet reactivity in extremely low birth weight infants undergoing erythropoietin therapy for treatment of anaemia of prematurity

scientific article published on 01 January 2005

Characterization of recombinant human diamine oxidase (rhDAO) produced in Chinese Hamster Ovary (CHO) cells.

scientific article published on 7 April 2016

Chikungunya vaccines in development

scientific article

Clazakizumab in late antibody-mediated rejection: study protocol of a randomized controlled pilot trial

scientific article published on 11 January 2019

Clinical Experience With Numeta in Preterm Infants: Impact on Nutrient Intake and Costs

scientific article

Clopidogrel in Critically Ill Patients

scientific article published on 15 September 2017

Coagulation interventions in experimental human endotoxemia

scientific article published on November 2006

Colistin dampens fibrinolysis and endothelial activation during endotoxaemia. A randomised, double blind trial.

scientific article published on 10 August 2017

Combined integrated protocol/basket trial design for a first-in-human trial

scientific article published on 04 October 2016

Comparison of a new ELISA-based with the flow cytometric assay for vasodilator-associated stimulated phosphoprotein (VASP) phosphorylation to assess P2Y12 -inhibition after ticagrelor intake

scientific article

Comparison of a new ELISA-based with the flow cytometric assay for vasodilator-associated stimulated phosphoprotein phosphorylation to assess P2Y12 -inhibition after ticagrelor intake

scientific article published on 26 August 2013

Condensation of delta-1-piperideine-6-carboxylate with ortho-aminobenzaldehyde allows its simple, fast, and inexpensive quantification in the urine of patients with antiquitin deficiency

scientific article published on 13 January 2020

Continuous thrombin infusion leads to a bleeding phenotype in sheep

scientific article published on 30 January 2012

Correction: Does Visceral Osteopathic Treatment Accelerate Meconium Passage in Very Low Birth Weight Infants?- A Prospective Randomized Controlled Trial.

scientific article published on 2 November 2017

Corrigendum to "Characterization of recombinant human diamine oxidase (rhDAO) produced in Chinese Hamster Ovary (CHO) cells" [J. Biotechnol. 227 (2016) 120-130].

scientific article published on 4 June 2016

Cross validation of aspirin effect in healthy individuals by Impact-R and PFA-100: a double blind randomized placebo controlled trial

scientific article published on May 2009

Cross validation of the Multiple Electrode Aggregometry. A prospective trial in healthy volunteers

scientific article published in August 2009

Crushed sublingual versus oral ticagrelor administration strategies in patients with unstable angina. A pharmacokinetic/pharmacodynamic study

scientific article published on 16 February 2017

D-dimer and histamine in early stage bacteremia: A prospective controlled cohort study

scientific article published on 13 November 2015

Defibrotide enhances fibrinolysis in human endotoxemia - a randomized, double blind, crossover trial in healthy volunteers

scientific article published on 31 July 2019

Desmopressin antagonizes the in vitro platelet dysfunction induced by GPIIb/IIIa inhibitors and aspirin

scientific article (publication date: 15 December 2003)

Detecting aspirin resistance with the Platelet Function Analyzer (PFA-100) ⬇️

scientific article (publication date: December 2001)

Dexamethasone down-regulates the expression of L-selectin on the surface of neutrophils and lymphocytes in humans*

scientific article published on 01 November 1997

Different Heparin Contents in Prothrombin Complex Concentrates May Impair Blood Clotting in Outpatients With Ventricular Assist Devices Receiving Phenprocoumon.

scientific article

Different Types of Coagulase Are Associated With 28-Day Mortality in Patients With Staphylococcus aureus Bloodstream Infections

scientific article published on 19 May 2020

Differential Osteoprotegerin Kinetics after Stimulation with Desmopressin and Lipopolysaccharides In Vivo

scientific article published on 29 May 2020

Differential induction of P‐selectin expression on platelets by two cell separators during plateletpheresis and the effect of gender on the release of soluble P‐selectin ⬇️

scientific article published on January 1, 1998

Differential regulation of human thrombospondin-1 upon systemic desmopressin versus endotoxin challenge

scholarly article published in May 2024

Direct evidence for an increase in thrombopoiesis after liver transplantation ⬇️

scientific article published on September 1, 1998

Disseminated Intravascular Coagulation score predicts mortality in patients with liver disease and low fibrinogen level.

scientific article published in 2022

Disseminated intravascular coagulation in heat stroke: a hot topic

scientific article published on 01 April 2012

Dissociation between systemic and pulmonary anti-inflammatory effects of dexamethasone in humans

scientific article published on 9 December 2015

Does Phosphodiesterase III Inhibition Reverse the Cardiodepressive Effects of Propofol? ⬇️

scientific article published on October 1, 1997

Does acute alcohol intoxication cause transaminase elevations in children and adolescents?

scientific article published on 30 January 2016

Does visceral osteopathic treatment accelerate meconium passage in very low birth weight infants?- A prospective randomized controlled trial

scientific article

Dual non-responsiveness to antiplatelet treatment is a stronger predictor of cardiac adverse events than isolated non-responsiveness to clopidogrel or aspirin

scientific article published on 2 February 2012

Duffy antigen modifies the chemokine response in human endotoxemia

scientific article published in January 2008

Dynamic assessment of venous thromboembolism risk in patients with cancer by longitudinal D-Dimer analysis: A prospective study

scientific article published on 19 February 2020

ELBW infants receive inadvertent sodium load above the recommended intake

scientific article published on 09 April 2020

Editorial on low-dose acetylsalicylic acid treatment and impact on short-term mortality in Staphylococcus aureus bloodstream infection: a propensity score-matched cohort study

scientific article published on May 2016

Effect of factor X inhibition on coagulation activation and cytokine induction in human systemic inflammation

scientific article published on 08 October 2002

Effect of fortifiers and additional protein on the osmolarity of human milk: is it still safe for the premature infant?

scientific article

Effect of interleukin-6 blockade on tissue factor-induced coagulation in human endotoxemia

scientific article published in May 2004

Effect of pre-existing anti-tick-borne encephalitis virus immunity on neutralising antibody response to the Vero cell-derived, inactivated Japanese encephalitis virus vaccine candidate IC51.

scientific article published on 17 September 2008

Effect of preanalytical time-delay on platelet function as measured by multiplate, PFA-100 and VerifyNow

scientific article

Effects of Indomethacin on the l‐selectin Expression in Humans ⬇️

scientific article published on 01 November 2001

Effects of SGLT2 Inhibitors on Ion Homeostasis and Oxidative Stress associated Mechanisms in Heart Failure

scientific article published in November 2021

Effects of a combined therapy of erythropoietin, iron, folate, and vitamin B12 on the transfusion requirements of extremely low birth weight infants

scientific article published in November 2006

Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia.

scientific article published on January 2010

Effects of carbon monoxide inhalation during experimental endotoxemia in humans

scientific article published on 19 November 2004

Effects of enalapril on disseminated intravascular thrombin formation during systemic inflammation

scientific article published in October 2003

Effects of endothelin-1 (ET-1) on ocular hemodynamics ⬇️

scientific article published on 01 July 1997

Effects of endothelin-1 and phenylephrine on plasma levels of von Willebrand factor and protein S.

scientific article published on 3 September 2009

Effects of endothelin‐1 on circulating adhesion molecules in man ⬇️

scientific article published on October 1, 1997

Effects of exercise on circulating vascular adhesion molecules in healthy men ⬇️

scientific article published on 01 November 1997

Effects of granulocyte colony stimulating factor on retinal leukocyte and erythrocyte flux in the human retina

scientific article

Effects of histamine and nitric oxide synthase inhibition on plasma levels of von Willebrand factor antigen ⬇️

scientific article published on 01 February 1998

Effects of nitroglycerin and sodium nitroprusside on endexpiratory concentrations of nitric oxide in healthy humans ⬇️

scientific article published on 01 January 1998

Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

scientific article

Effects of prasugrel on platelet inhibition during systemic endotoxaemia: a randomized controlled trial.

scientific article published in November 2012

Effects of testosterone suppression on serum levels of hepatitis B surface antigen and HBV‐DNA in men ⬇️

scientific article published on June 1, 1998

Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia.

scientific article published in April 2008

Elevated numbers of reticulated platelets in hyperthyroidism: direct evidence for an increase of thrombopoiesis ⬇️

scientific article published on June 1, 1998

Elevated serum transaminases in patients with acute coronary syndromes: Do we need a revision of exclusion criteria for clinical trials?

scientific article published on 2 August 2021

Enalapril does not alter adhesion molecule levels in human endotoxemia

scientific article published in May 2003

Endotoxaemia modulates Toll-like receptors on leucocytes in humans

scientific article published on 01 May 2003

Endotoxemia enhances expression of the signaling receptor (GP130) on protein and molecular level

scientific article published on 01 March 2005

Endotoxin down-modulates P-selectin glycoprotein ligand-1 (PSGL-1, CD162) on neutrophils in humans

scientific article published in January 2004

Enhanced Blood Coagulation and Enhanced Fibrinolysis during Hemodialysis with Prostacyclin ⬇️

scientific article published on 01 November 1997

Ethnic differences in plasma levels of interleukin-8 (IL-8) and granulocyte colony stimulating factor (G-CSF)

scientific article published on 01 January 2007

Evaluation of antiinflammatory and antiadhesive effects of heparins in human endotoxemia

scientific article published on 01 April 2003

Evaluation of bedside prothrombin time and activated partial thromboplastin time measurement by coagulation analyzer CoaguCheck Plus in various clinical settings ⬇️

scientific article published on 01 September 1997

Evaluation of between-, within- and day-to-day variation of coagulation measured by rotational thrombelastometry (ROTEM).

scientific article

Evaluation of coagulation markers for early diagnosis of acute coronary syndromes in the emergency room

scientific article published on 01 November 2002

Evidence Against an Effect of Endothelin-1 on Blood Coagulation, Fibrinolysis, and Endothelial Cell Integrity in Healthy Men ⬇️

scientific article published on 01 November 1997

Ex vivo properties of plasma clot formation and lysis in patients with cancer at risk for venous thromboembolism, arterial thrombosis, and death

scientific article published on 29 August 2019

False-positive pregnancy test after transfusion of solvent/detergent-treated plasma

scientific article published on 14 September 2017

Female gender, menstrual cycle and estradiol affect plasma levels of monocyte chemotactic protein-1 (MCP-1) in humans

scientific article

Fosinopril decreases levels of soluble vascular cell adhesion molecule-1 in Type II diabetic patients suffering from microalbuminuria ⬇️

scientific article published on 01 August 1998

Function of platelets in apheresis platelet concentrates and in patient blood after transfusion as assessed by Impact-R.

scientific article

Functional capillary impairment in patients with ventricular assist devices

scientific article published on 11 April 2019

Genetic variations and their influence on risk and treatment of venous thrombosis

scientific article published on April 2008

Glucocorticoids Dose-Dependently Increase Plasma Levels of Granulocyte Colony Stimulating Factor in Man ⬇️

scientific article published on 01 March 1998

Glycoprotein Ib polymorphisms influence platelet plug formation under high shear rates

scientific article published in February 2003

Granulocyte colony-stimulating factor (G-CSF) increases histone-complexed DNA plasma levels in healthy volunteers.

scientific article

Growth, Feeding Tolerance and Metabolism in Extreme Preterm Infants under an Exclusive Human Milk Diet

scientific article published on 26 June 2019

Hemostasis in cardiac arrest patients treated with mild hypothermia initiated by cold fluids

scientific article published on 29 April 2009

High Platelet Reactivity after Transition from Cangrelor to Ticagrelor in Hypothermic Cardiac Arrest Survivors with ST-Segment Elevation Myocardial Infarction

scientific article published on 21 February 2020

High Titer Persistent Neutralizing Antibodies Induced by TSST-1 Variant Vaccine Against Toxic Shock Cytokine Storm

scientific article published on 02 October 2020

High dose dexamethasone increases circulating P-selectin and von Willebrand factor levels in healthy men

scientific article published on 01 October 2005

Homozygosity in the single nucleotide polymorphism Ser128Arg in the E-selectin gene associated with recurrent venous thromboembolism

scientific article published on 01 August 2006

Human Milk Analyser shows that the lactation period affects protein levels in preterm breastmilk

scientific article published on 6 March 2016

Human diamine oxidase cellular binding and internalization in vitro and rapid clearance in vivo are not mediated by N-glycans but by heparan sulfate proteoglycan interactions

scientific article published on 26 September 2020

Human diamine oxidase is readily released from activated neutrophils ex vivo and in vivo but is rarely elevated in bacteremic patients

scientific article published on 01 January 2020

Hydroxychloroquine versus lopinavir/ritonavir in severe COVID-19 patients : Results from a real-life patient cohort

scientific article published on 10 August 2020

Hypertensive emergencies are associated with elevated markers of inflammation, coagulation, platelet activation and fibrinolysis ⬇️

scientific article published on December 20, 2012

Immunogenicity and safety of different injection routes and schedules of IC41, a Hepatitis C virus (HCV) peptide vaccine.

scientific article published on 9 January 2010

Immunogenicity and safety of the inactivated Japanese encephalitis vaccine IXIARO® in elderly subjects: Open-label, uncontrolled, multi-center, phase 4 study

scientific article published on 23 July 2016

Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial

scientific article

Immunomodulatory effects of fosfomycin in an endotoxin model in human blood

scientific article published on 16 November 2006

Impact of clopidogrel loading dose on clinical outcome in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis

scientific article published on 23 August 2010

Impact of morphine on antiplatelet effects of oral P2Y12 receptor inhibitors

scientific article

In Vivo Study of the Effect of Exogenous Estradiol on α-Adrenoceptor Responsiveness of Human Veins ⬇️

scientific article published on June 1, 1994

In vitro platelet function of platelet concentrates prepared using three different apheresis devices determined by impedance and optical aggregometry

scientific article published on 01 August 2009

In vivo profile of the human leukocyte microRNA response to endotoxemia.

scientific article

In-vivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model.

scientific article

Increased Citrullinated Histone H3 Levels in the Early Post-Resuscitative Period Are Associated with Poor Neurologic Function in Cardiac Arrest Survivors-A Prospective Observational Study

scientific article published on 01 October 2019

Increased Fibrinolysis as a Specific Marker of Poor Outcome After Cardiac Arrest

scientific article published on 01 October 2018

Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration

scientific article published on 08 February 2011

Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia.

scientific article published on 26 February 2004

Influence of METHoxyflurane on ANtiplatelet Effect of ticagrelor in patients with unstable angina pectoris: Rationale and a protocol of a randomized clinical METHANE-SIRIO 4 study

scientific article published on 7 April 2022

Influence of proton pump inhibitors andVKORC1mutations on CYP2C9-mediated dose requirements of vitamin K antagonist therapy: a pilot study

scientific article published on 21 August 2014

Inhibition of Protease-Activated Receptor (PAR1) Reduces Activation of the Endothelium, Coagulation, Fibrinolysis and Inflammation during Human Endotoxemia

scientific article published on 04 June 2018

Inhibition of complement C1s improves severe hemolytic anemia in cold agglutinin disease: a first-in-human trial

scientific article published on 17 December 2018

Inhibition of complement C1s in patients with cold agglutinin disease: lessons learned from a named patient program

scientific article published on 01 March 2020

Inhibition of tissue factor pathway inhibitor (TFPI) by ARC19499 improves clotting of hemophiliac blood.

scientific article published on 16 November 2010

Inhibition of von Willebrand factor by ARC1779 in patients with acute thrombotic thrombocytopenic purpura

scientific article

Interdependence between osteoprotegerin and active von Willebrand factor in long-term cardiovascular mortality prediction in patients undergoing percutaneous coronary intervention.

scientific article published on 20 July 2017

Interference in specialized coagulation assays affecting the protein C pathway: Effects of marked haemolysis, hyperbilirubinaemia and lipaemia on chromogenic and clotting tests on two coagulation platforms

scientific article published on 12 March 2019

Interleukin-6 level is a powerful predictor of long-term cardiovascular mortality in patients with acute coronary syndrome

scientific article published on 07 October 2020

Interplay between genetic and clinical variables affecting platelet reactivity and cardiac adverse events in patients undergoing percutaneous coronary intervention

scientific article

Interspecies differences in coagulation profile

Interspecies differences in coagulation profile

LPS-induced microvascular leukocytosis can be assessed by blue-field entoptic phenomenon

scientific article published on 11 March 2004

LUBAC and ABIN-1 Modulate TRAIL-Based NF-κB Induction in Human Embryonic Kidney 293 Cells.

scientific article

Levels of adhesion molecules do not decrease after 3 months of statin therapy in moderate hypercholesterolaemia

scientific article

Limitations of a calibrated, quantitative APC-R assay under routine conditions

scientific article published on 01 November 2020

Long term immunity following a booster dose of the inactivated Japanese Encephalitis vaccine IXIARO®, IC51

scientific article published in 2011

Low PCSK-9 levels Are Associated with Favorable Neurologic Function after Resuscitation from out of Hospital Cardiac Arrest

scientific article published on 11 August 2020

Low-dose ticagrelor with or without acetylsalicylic acid in patients with acute coronary syndrome: Rationale and design of the ELECTRA-SIRIO 2 trial

scientific article published in 2022

MMP-8 genotypes influence the inflammatory response in human endotoxemia.

scientific article

Massive release of the histamine-degrading enzyme diamine oxidase during severe anaphylaxis in mastocytosis patients

scientific article published on 01 January 2019

Measurement of the levels of reticulated platelets after plateletpheresis to monitor activity of thrombopoiesis ⬇️

scientific article published on 01 May 1998

Mechanism of action of drotrecogin alfa activated (rhAPC).

scientific article published in May 2004

Menstrual cycle-associated changes in blood levels of interleukin-6, α1 acid glycoprotein, and C-reactive protein ⬇️

scientific article published on July 1, 1997

Microarray-based Detection of Allergen-Reactive IgE in Patients with Mastocytosis

scientific article published on 26 April 2020

Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells

scientific article published on 08 May 2019

Morphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy Volunteers

scientific article published on 14 March 2018

Morphine decreases clopidogrel concentrations and effects: a randomized, double-blind, placebo-controlled trial

scientific article

Morphine decreases ticagrelor concentrations but not its antiplatelet effects: a randomized trial in healthy volunteers

scientific article published on 23 November 2015

Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial

scientific article

Morphine interaction with prasugrel: a double-blind, cross-over trial in healthy volunteers

scientific article published on 22 October 2015

Neutrophil-Mediated Proteolysis of Thrombospondin-1 Promotes Platelet Adhesion and String Formation

scientific article published on 12 November 2018

Oligomannosidic glycans at Asn110 are essential for secretion of human diamine oxidase.

scientific article published on 29 November 2017

Oral NAloxone to overcome the moRphine effect in acute COronary syndrome patients treated with TICagrelor - NARCOTIC trial

scientific article published on 24 March 2020

Patients with severe aortic valve stenosis and impaired platelet function benefit from preoperative desmopressin infusion

scientific article published on 24 March 2011

Personalized antiplatelet treatment after percutaneous coronary intervention: The MADONNA study

Pharmacodynamics of active site-inhibited factor VIIa in endotoxin-induced coagulation in humans

scientific article published on October 2002

Pharmacokinetic Modeling of Morphine's Effect on Plasma Concentrations of Ticagrelor and Its Metabolite in Healthy Volunteers

scientific article published in 2021

Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases

scientific article

Pharmacokinetics (PK) of S/D treated anti-D immunoglobulin after intramuscular injection in healthy volunteers: gender differences in PK

scientific article published on 01 October 2005

Pharmacokinetics of Lopinavir and Ritonavir in Patients Hospitalized With Coronavirus Disease 2019 (COVID-19)

scientific article published on 12 May 2020

Pharmacokinetics of a Novel Anagrelide Extended-Release Formulation in Healthy Subjects: Food Intake and Comparison With a Reference Product.

scientific article published on 16 March 2017

Plasmatic tissue factor pathway inhibitor is a major determinant of clotting in factor VIII inhibited plasma or blood

scientific article published on 24 January 2013

Plasminogen activator inhibitor-1 4G/5G genotype and residual venous occlusion following acute unprovoked deep vein thrombosis of the lower limb: A prospective cohort study

scientific article published on 16 March 2017

Platelet activation at the onset of human endotoxemia is undetectable in vivo

scientific article

Platelet dysfunction in outpatients with left ventricular assist devices

scientific article published in January 2009

Platelet function in mitochondriopathy with stroke and stroke-like episodes

scientific article published in March 2004

Platelet function predicts myocardial damage in patients with acute myocardial infarction

scientific article (publication date: 14 September 2004)

Platelet function under high-shear conditions from platelet concentrates

scientific article published on 24 September 2007

Platelet glycoprotein Ibα polymorphisms and function evaluated by the platelet function analyzer PFA-100 in patients with lupus anticoagulant: the association with thromboembolic disease

scientific article published on 19 July 2007

Platelet hyperfunction is decreased by additional aspirin loading in patients presenting with myocardial infarction on daily aspirin therapy.

scientific article published in June 2010

Platelet inhibition with standard vs. lower maintenance dose of ticagrelor early after myocardial infarction (ELECTRA): a randomized, open-label, active-controlled pharmacodynamic and pharmacokinetic study

scientific article published on 01 July 2019

Point of care measurement of lepirudin and heparin anticoagulation during systemic inflammation

scientific article

Potent and rapid reversal of the von Willebrand Factor Inhibitor Aptamer BT200

scientific article published on 10 April 2020

Potent irreversible P2Y12 inhibition does not reduce LPS-induced coagulation activation in a randomized, double-blind, placebo-controlled trial

scientific article

Prasugrel in critically ill patients

scientific article published on 06 July 2017

Pregnancy-associated diamine oxidase originates from extravillous trophoblasts and is decreased in early-onset preeclampsia

scientific article published on 20 April 2018

Prevalence and Clinical Impact of Reduced Coagulation Factor XII Activity in Patients Receiving Extracorporeal Membrane Oxygenation

scientific article published in 2021

Procoagulant extracellular vesicles in amniotic fluid

scientific article

Product review on the JE vaccine IXIARO

scientific article

Prognosis of overt disseminated intravascular coagulation in patients admitted to a medical emergency department

scientific article published on 23 December 2015

Prolonged Activated Partial Thromboplastin Time after Successful Resuscitation from Cardiac Arrest is Associated with Unfavorable Neurologic Outcome

scientific article published on 13 November 2020

Prolonged antithrombotic therapy in patients after acute coronary syndrome: A critical appraisal of current European Society of Cardiology guidelines

scientific article published on 19 October 2020

Prolonged antithrombotic therapy in patients after acute coronary syndrome: A critical appraisal of current European Society of Cardiology guidelines

Pronounced platelet hyperfunction in patients with cardiac arrest achieving restoration of spontaneous circulation

scientific article

Protease-Activated Receptors 1 and 3 are Differentially Expressed on Human Monocyte Subsets and are Upregulated by Lipopolysaccharide Ex Vivo and In Vivo

scientific article published on 10 July 2019

Putative Role of Adhesion Molecules in Metabolic Disorders ⬇️

scientific article published on December 1, 1997

Quality Criteria for Real-world Data in Pharmaceutical Research and Health Care Decision-making: Austrian Expert Consensus

scientific article published in 2022

Quantification of human diamine oxidase.

scientific article published on 29 December 2016

Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Study of the Penetration of a Monoclonal Antibody Combination (ASN100) Targeting Staphylococcus aureus Cytotoxins in the Lung Epithelial Lining Fluid of Healthy Volunteers

scientific article published on 25 July 2019

Rapid down modulation of P-selectin glycoprotein ligand-1 (PSGL-1, CD162) by G-CSF in humans.

scientific article published in March 2002

Rationale and Design of the Effectiveness of LowEr maintenanCe dose of TicagRelor early After myocardial infarction (ELECTRA) pilot study

scientific article published on 10 October 2017

Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia

scientific article published on 15 May 2003

Recombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia

scientific article published in January 2006

Recombinant human diamine oxidase activity is not inhibited by ethanol, acetaldehyde, disulfiram, diethyldithiocarbamate or cyanamide

scientific article published on 29 June 2016

Recovery, safety, and tolerability of a solvent/detergent-treated and prion-safeguarded transfusion plasma in a randomized, crossover, clinical trial in healthy volunteers

scientific article published on 16 January 2013

Regional cortical development in very low birth weight infants with normal neurodevelopmental outcome assessed by 3D-ultrasound ⬇️

scientific article published on December 20, 2012

Regulation of Fas (APO-1, CD95) and Fas ligand expression in leukocytes during systemic inflammation in humans.

scientific article

Regulation of histamine and diamine oxidase in patients undergoing orthotopic liver transplantation

scientific article published on 21 January 2020

Regulation of protease-activated receptor 1 (PAR1) on platelets and responsiveness to thrombin receptor activating peptide (TRAP) during systemic inflammation in humans

scientific article published on 01 November 2003

Reproducibility and standardized reporting of the vasodilator-stimulated phosphoprotein phosphorylation assay

scientific article published in November 2008

Response to Letter by Tho

Response to Letter by van Werkum: Proton pump inhibitors and clopidogrel: a difficult dilemma

Response to vWF-coated beads and soluble p-selectin to characterize apheresis platelets: a comparison of three cell separators

scientific article published on 01 March 2002

Reversal strategy in antagonizing the P2Y12 -inhibitor ticagrelor.

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Risk factors cannot explain the higher prevalence rates of precancerous colorectal lesions in men.

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Risk of venous thromboembolism in patients with COVID-19: A systematic review and meta-analysis

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Routine haematological parameters in COVID-19 prognosis

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Safety analysis of a Vero-cell culture derived Japanese encephalitis vaccine, IXIARO (IC51), in 6 months of follow-up

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Safety of a universal, virus-inactivated and prion-depleted, pharmaceutical-quality plasma: a randomized, double-blind, clinical trial in healthy volunteers

scientific article published on 18 February 2011

Safety, immunogenicity and dose response of VLA84, a new vaccine candidate against Clostridium difficile, in healthy volunteers

scientific article published on 11 April 2016

Safety, tolerability, and immunogenicity of a recombinant toxic shock syndrome toxin (rTSST)-1 variant vaccine: a randomised, double-blind, adjuvant-controlled, dose escalation first-in-man trial

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Safety, tolerability, pharmacokinetics and pharmacodynamics of parenterally administered dutogliptin: A prospective dose-escalating trial

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Selective glucocorticoid receptor modulation inhibits cytokine responses in a canine model of mild endotoxemia

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Serum and Lung Pharmacokinetics of ASN100, a Monoclonal Antibody Combination for the Prevention and Treatment of Staphylococcus aureus Pneumonia

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Short-chain methotrexate polyglutamate MTXPG2 as outcome parameter in rheumatoid arthritis.

scientific article published on 16 November 2010

Simple, sensitive and specific quantification of diamine oxidase activity in complex matrices using newly discovered fluorophores derived from natural substrates

scientific article published on 01 June 2020

Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by isocratic high-pressure liquid chromatography with post-column hydrolysis and fluorescence detection

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Simvastatin and rosuvastatin mobilize Endothelial Progenitor Cells but do not prevent their acute decrease during systemic inflammation.

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Single dose granulocyte colony-stimulating factor markedly enhances shear-dependent platelet function in humans.

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Single, very low rituximab doses in healthy volunteers - a pilot and a randomized trial: implications for dosing and biosimilarity testing

scientific article published on 9 January 2018

Small volume enemas do not accelerate meconium evacuation in very low birth weight infants

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Specific Inhibition of the Classical Complement Pathway Prevents C3 Deposition along the Dermal-Epidermal Junction in Bullous Pemphigoid

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Starting enteral nutrition with preterm single donor milk instead of formula affects time to full enteral feeding in very low birthweight infants.

scientific article published on 12 May 2017

Sublingual functional capillary rarefaction in chronic heart failure

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Sublingual microvasculature in diabetic patients

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Surface cooling for induction of mild hypothermia in conscious healthy volunteers - a feasibility trial ⬇️

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Targeting von Willebrand Factor in Ischaemic Stroke: Focus on Clinical Evidence

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Targeting von Willebrand factor and platelet glycoprotein Ib receptor

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Tecarfarin: A Novel Vitamin K Antagonist

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The C-reactive protein (+)1444C/T alteration modulates the inflammation and coagulation response in human endotoxemia

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The EGF A61G Polymorphism Is Associated with Disease-Free Period and Survival in Malignant Melanoma

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The ISTH DIC score predicts outcome in non-septic patients admitted to a cardiovascular intensive care unit

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The Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms influence the late inflammatory response in human endotoxemia

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The anti-von Willebrand factor aptamer ARC1779 increases von Willebrand factor levels and platelet counts in patients with type 2B von Willebrand disease

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The aptamer ARC1779 blocks von Willebrand factor-dependent platelet function in patients with thrombotic thrombocytopenic purpura ex vivo

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The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor mediated ex vivo platelet function in acute myocardial infarction.

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The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor-mediated platelet function in ST-elevation and non-ST-elevation acute myocardial infarction

The aptamer BT200 effectively inhibits von Willebrand factor (VWF) dependent platelet function after stimulated VWF release by desmopressin or endotoxin

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The development and characterization of a long acting anti-thrombotic von Willebrand factor (VWF) aptamer

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The effect of an osmotic contrast agent on complete meconium evacuation in preterm infants.

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The effect of antiplatelet drugs clopidogrel and aspirin is less immediately after stent implantation

scientific article published on 9 January 2009

The effect of erythropoietin on platelet and endothelial activation markers: a prospective trial in healthy volunteers

scientific article published on 18 November 2011

The effect of plasma removal from apheresis platelet concentrates on platelet function

scientific article published on September 16, 2011

The effects of supra-normal protein C levels on markers of coagulation, fibrinolysis and inflammation in a human model of endotoxemia

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The fibrinogen -148 C/T polymorphism influences inflammatory response in experimental endotoxemia in vivo

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The inflammatory response is influenced by FXIII VAL 34 LEU polymorphism in a human LPS model

scientific article published on 01 January 2009

The influence of methotrexate on the gene expression of the pro-inflammatory cytokine IL-12A in the therapy of rheumatoid arthritis

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The interleukin-6 G(-174)C promoter polymorphism does not determine plasma interleukin-6 concentrations in experimental endotoxemia in humans

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The net clinical benefit of personalized antiplatelet therapy in patients undergoing percutaneous coronary intervention

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The pharmacokinetics of subcutaneously injected Bimosiamose disodium in healthy male volunteers

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The single nucleotide polymorphism Ser128Arg in the E-selectin gene is associated with enhanced coagulation during human endotoxemia

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The tumor necrosis factor alpha -308 G/A polymorphism does not influence inflammation and coagulation response in human endotoxemia

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The use of frozen plasma samples in thromboelastometry

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Therapeutic approaches in the management of oral cyclosporine A intoxication

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Thrombin as a multi-functional enzyme

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Thrombopoiesis Is Increased in Hyperthyroidisme ⬇️

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Ticagrelor and prasugrel are independent predictors of improved long-term survival in ACS patients

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Ticagrelor: From Discovery to Phase III Clinical Trial ⬇️

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Tolerability and pharmacokinetics of inhaled bimosiamose disodium in healthy males.

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Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial

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Top‐down proteomic analysis by MALDI‐TOF profiling: Concentration‐independent biomarkers ⬇️

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Torque Teno Virus Control by the Classical Pathway of Complement Activation—A Retrospective Analysis From a First‐in‐Human Trial Utilizing Sutimlimab

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Towards the development of specific antidotes: Idarucizumab for reversal of dabigatran effects

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Tranexamic acid and fibrinogen restore clotting in vitro and in vivo in cardiac thrombus associated hyperfibrinolysis with overt bleedings

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Upregulation of cytokine mRNA in circulating leukocytes during human endotoxemia

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VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP.

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Validation of a novel tissue factor assay in experimental human endotoxemia

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Variable inhibition of high-shear-induced platelet plug formation by eptifibatide and tirofiban under conditions of platelet activation and high von Willebrand release: a randomized, placebo-controlled, clinical trial

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Von Willebrand factor antigen levels predict major adverse cardiovascular events in patients with carotid stenosis of the ICARAS study

scientific article published on 17 September 2019

Why have studies of tailored anti-platelet therapy failed so far? ⬇️

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[Consensus statement: Stroke prevention in nonvalvular atrial fibrillation in special consideration of the new direct oral anticoagulants]

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profile of the human leukocyte microRNA response to endotoxemia

von Willebrand Factor Predicts Mortality in ACS Patients Treated with Potent P2Y12 Antagonists and is Inhibited by Aptamer BT200 Ex Vivo

scientific article published on 17 July 2020

von Willebrand factor in cardiovascular disease: focus on acute coronary syndromes.

scientific article published on March 2008

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