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List of works by Kristian W Pajtler

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Author Correction: The landscape of genomic alterations across childhood cancers

scientific article published in Nature

Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience

scientific article published on 22 April 2019

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

scientific article

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology

scientific article published on 7 February 2017

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment

scientific article published on 01 November 2018

Diagnostics of Paediatric Supratentorial RELA Ependymomas: Integration of information from Histopathology, Genetics, DNA Methylation and Imaging

article

EP-03MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS.

scientific article published on 21 April 2015

EPEN-04. CXorf67 MIMICS ONCOGENIC HISTONE H3 K27M MUTATIONS AND FUNCTIONS AS INTRINSIC INHIBITOR OF PRC2 FUNCTION IN AGGRESSIVE POSTERIOR FOSSA EPENDYMOMA

scientific article published on 23 April 2019

EPEN-05. CXorf67 EXPRESSION IS A PUTATIVE DRIVER OF PFA EPENDYMOMA

EPEN-06. YAP1 SUBGROUP SUPRATENTORIAL EPENDYMOMA REQUIRES TEAD AND NUCLEAR FACTOR I-MEDIATED TRANSCRIPTIONAL PROGRAMS FOR TUMORIGENESIS

scientific article published on 23 April 2019

EPEN-07. OVEREXPRESSION AND MUTATIONS OF CXORF67 IN ‘INFANT-TYPE’ POSTERIOR FOSSA TYPE-A (PFA) EPENDYMOMAS

article published in 2018

EPEN-10. ROLE OF DNA METHYLATION ANALYSIS IN RECURRENT PAEDIATRIC EPENDYMOMA.

scientific article published on 22 June 2018

EPEN-23. MOLECULAR HETEROGENEITY AMONG PEDIATRIC POSTERIOR FOSSA EPENDYMOMA

EPEN-24. YAP1 FUSION PROTEINS MEDIATE ONCOGENIC ACTIVITY IN EPENDYMOMA VIA INTERACTION WITH TEAD TRANSCRIPTION FACTORS.

scientific article published on 22 June 2018

EPEN-28. HETEROGENEITY WITHIN THE PFB EPENDYMOMA SUBGROUP.

scientific article published on 22 June 2018

EPN-07IMPACT OF CHROMOSOMAL ABERRATIONS AND MOLECULAR SUBTYPE ON TELOMERASE ACTIVATION IN PEDIATRIC EPENDYMOMA.

scientific article published on 30 May 2016

EPN-12PEDIATRIC SUPRATENTORIAL EPENDYMOMA: COMPARISON BETWEEN IMMUNOHISTOCHEMISTRY, FISH AND DNA METHYLATION ANALYSIS FOR RELA REARRANGEMENT AND HISTOLOGICAL CORRELATION.

scientific article published on 30 May 2016

EPN-30YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE.

scientific article published on 30 May 2016

EPN-31MOLECULAR REFINEMENT OF PEDIATRIC POSTERIOR FOSSA EPENDYMOMA.

scientific article published on 30 May 2016

EPN-34EPIGENOMIC ANALYSIS OF EPENDYMAL TUMORS IDENTIFIES SUBGROUP SPECIFIC ENHANCERS CONTROLLING DISTINCT REGULATORY CIRCUITRIES.

scientific article published on 30 May 2016

EPND-01. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS.

scientific article published on 31 May 2017

EPND-02. GENOMIC COPY NUMBER ALTERATIONS IN EPENDYOMOMA.

scientific article

EPND-07. MOLECULAR HETEROGENEITY AMONG PEDIATRIC POSTERIOR FOSSA EPENDYMOMA.

scientific article published on 31 May 2017

EPND-13. YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE.

scientific article

EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma

scientific article published on 01 July 2019

Ependymoma

scientific article published on 01 February 2018

Epidemiology, molecular classification and WHO grading of ependymoma

scientific article published on 8 September 2017

Evaluation of Storage Tubes for Combined Analysis of Circulating Nucleic Acids in Liquid Biopsies ⬇️

scientific article published on 06 February 2019

Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cells.

scientific article published on 16 March 2013

FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.

scientific article

GENE-02. CHROMOSOME CONFORMATION ANALYSIS OF EPENDYMOMA IDENTIFIES PUTATIVE TUMOR DEPENDENCY GENES ACTIVATED BY DISTAL ONCOGENIC ENHANCERS

scientific article published on 23 April 2019

GENE-12. ANAPLASTIC NEUROEPITHELIAL TUMOR WITH CONDENSED NUCLEI (ANTCON): A NOVEL BRAIN TUMOR ENTITY WITH RECURRENT NTRK FUSION

Genetic confirmation that ependymoma can arise as part of multiple endocrine neoplasia type 1 (MEN1) syndrome.

scientific article published on 25 February 2017

Germline Elongator mutations in Sonic Hedgehog medulloblastoma

scientific article published on 01 April 2020

Heterogeneity within the PF-EPN-B ependymoma subgroup

article

INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies

scientific article published on 05 June 2020

Intraventricular etoposide safety and toxicity profile in children and young adults with refractory or recurrent malignant brain tumors

scientific article published on 4 May 2016

Limitations of current models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymoma

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

scientific article published on 20 August 2016

MPTH-26MOLECULAR REFINEMENT OF PEDIATRIC POSTERIOR FOSSA EPENDYMOMA.

scientific article

MYCN amplification drives an aggressive form of spinal ependymoma

scientific article published on 14 August 2019

MiR-34a deficiency accelerates medulloblastoma formation in vivo

scientific article

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

scientific article

Molecular characterization of histopathological ependymoma variants

scientific article published on 02 November 2019

Molecular dissection of ependymomas

scientific article published on 20 August 2015

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas

scientific article published on 16 June 2018

Molecular mechanisms and therapeutic targets in pediatric brain tumors.

scientific article published on 14 March 2017

Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood

scientific article published on July 2017

Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells. ⬇️

scientific article

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series

scientific article published on 08 March 2019

PATH-32. MOLECULAR HETEROGENEITY AMONG PEDIATRIC POSTERIOR FOSSA EPENDYMOMA

PCLN-06. NOVEL TUMOR-DERIVED MODELS OF CNS HGNET-BCOR PROVIDE INSIGHTS INTO UNDERLYING MOLECULAR MECHANISMS AND INNOVATIVE THERAPEUTIC OPTIONS

PDTM-23. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity

scientific article

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

scientific article

Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk

scientific article published on June 2017

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

scientific article published on 05 August 2021

Response to trametinib treatment in progressive pediatric low-grade glioma patients

scientific article published on 07 October 2020

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

scientific article published on 01 July 2020

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

scientific article

Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies

scientific article published on 16 October 2021

Targeting fibroblast growth factor receptors to combat aggressive ependymoma

scientific article published on 27 May 2021

Telomerase activation in posterior fossa group A ependymomas is associated with dismal prognosis and chromosome 1q gain

scientific article

Telomere dysfunction and chromothripsis

scientific article published on 9 February 2016

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.

scientific article published on 27 December 2016

The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma

scientific article published on 29 May 2013

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants

scientific article

The landscape of genomic alterations across childhood cancers

scientific article published on 28 February 2018

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis

scientific article published on 06 June 2016

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

scientific article published on 20 December 2017

Toward an integrated histomolecular diagnosis of supratentorial ependymoma

scientific article published on 3 April 2016

Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker

scientific article published on 28 November 2019

Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q

scientific article published on 01 August 2021

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

scientific article published on 02 September 2019

YAP1-fusions in pediatric NF2-wildtype meningioma

scientific article published on 16 November 2019

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