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List of works by John Zalcberg

5-fluorouracil: a pharmacological paradigm in the use of cytotoxics

scientific article published on 01 November 1998

A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer

scientific article published on 4 January 2013

A novel combination of cisplatin, irinotecan, and capecitabine in patients with advanced cancer

scientific article

A phase I dose-escalation study of docetaxel with granulocyte colony-stimulating factor support in patients with solid tumours ⬇️

scientific article published on May 1, 2003

A phase I trial of Capecitabine+Gemcitabine with radical radiation for locally advanced pancreatic cancer

scientific article published on 16 December 2008

A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer

scientific article published on September 2004

A phase I/II trial of celecoxib with chemotherapy and radiotherapy in the treatment of patients with locally advanced oesophageal cancer

scientific article published on 20 October 2006

A phase II study of the heparanase inhibitor PI-88 in patients with advanced melanoma

scientific article

Accepting risk in the acceleration of drug development for rare cancers

scientific article published on April 2015

Addition of gabapentin to a modified FOLFOX regimen does not reduce oxaliplatin-induced neurotoxicity

scientific article published on 01 July 2006

Adjuvant therapy of colorectal cancer: an overview.

scientific article published on January 1991

Advances in Molecular Pathology and Treatment of Periampullary Cancers

scientific article published on 04 September 2015

Age does not influence efficacy of ramucirumab in advanced gastric cancer: Subgroup analyses of REGARD and RAINBOW.

scientific article

Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance.

scientific article

An International Collaborative Standardizing a Comprehensive Patient-Centered Outcomes Measurement Set for Colorectal Cancer

scientific article published on 6 April 2017

An appraisal of analytical tools used in predicting clinical outcomes following radiation therapy treatment of men with prostate cancer: a systematic review

scientific article published on 21 March 2017

An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin

scientific article

An overview of experimental and investigational multikinase inhibitors for the treatment of metastatic colorectal cancer.

scientific article published on 27 July 2015

Antitumor effect of somatostatin analogs in neuroendocrine tumors.

scientific article published on 14 December 2009

Applications of positron emission tomography in the development of molecular targeted cancer therapeutics

scientific article published on January 2003

Association of hypomagnesemia with inferior survival in a phase III, randomized study of cetuximab plus best supportive care versus best supportive care alone: NCIC CTG/AGITG CO.17

scientific article published on 08 November 2012

Australian multicentre phase II trial of paclitaxel in women with metastatic breast cancer and prior chemotherapy

scientific article published on 01 May 1997

Barriers and enablers to the implementation of protocol-based imaging in pancreatic cancer: A qualitative study using the theoretical domains framework

scientific article published on 17 December 2020

Beyond 5-fluorouracil: new horizons in systemic therapy for advanced colorectal cancer

scientific article

Biosimilars are coming: ready or not

scientific article published on 01 September 2018

Broken doctor–patient relationships: why won't they listen?

scientific article published on 01 September 2014

CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

scientific article published on 17 July 2020

Cancer history and risk factors in healthy older people enrolling in the ASPREE clinical trial

scientific article published on 30 July 2020

Capecitabine, bevacizumab, and mitomycin in first-line treatment of metastatic colorectal cancer: results of the Australasian Gastrointestinal Trials Group Randomized Phase III MAX Study

scientific article

Cell graph neural networks enable the precise prediction of patient survival in gastric cancer

scientific article published in 2022

Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line.

scientific article published on May 1994

Cetuximab for the treatment of colorectal cancer.

scientific article

Challenges of international oncology trial collaboration-a call to action

scientific article published on 05 August 2019

Chemotherapy for advanced colorectal cancer

scientific article published on September 2000

Circumvention of doxorubicin resistance in multi-drug resistant human leukaemia and lung cancer cells by the pure antioestrogen ICI 164384.

scientific article published on January 1991

Circumvention of tamoxifen resistance by the pure anti-estrogen ICI 182,780.

scientific article published on November 1993

Clinical application of a rapid, functional assay for multidrug resistance based on accumulation of the fluorescent dye, fluo-3.

scientific article

Clinical utility of ramucirumab in advanced gastric cancer

scientific article

Comment on: 'Hospital lung surgery volume and patient outcomes'

scientific article published on 03 January 2020

Comparative effectiveness research — a proposal for a new NHMRC funding stream ⬇️

scientific article published on January 16, 2012

Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group

scientific article published on 22 June 2018

Controversies in the management of gastrointestinal stromal tumors

scientific article published on 27 March 2014

Correction to: Short-term outcome of emergency colorectal cancer surgery: results from Bi-National Colorectal Cancer Audit

scientific article published on 01 February 2019

Current and emerging strategies for the management of imatinib-refractory advanced gastrointestinal stromal tumors ⬇️

scientific article published on September 1, 2012

Cyclosporin A and PSC 833 prevent up-regulation of MDR1 expression by anthracyclines in a human multidrug-resistant cell line.

scientific article

Delivering affordable cancer care in high-income countries

article

Development and validation of prognostic nomograms for metastatic gastrointestinal stromal tumour treated with imatinib

scientific article published on 19 March 2015

Development of South Australian-Victorian Prostate Cancer Health Outcomes Research Dataset.

scientific article

Development of a binational thyroid cancer clinical quality registry: a protocol paper

article

Differential effects of estrogen, tamoxifen and the pure antiestrogen ICI 182,780 in human drug-resistant leukemia cell lines.

scientific article published on January 1993

Discussing Expensive Anticancer Drugs

scientific article published on 15 December 2008

Do all services provided as part of a clinical trial require research ethics and governance review?

scientific article published in October 2017

Dose optimization of tyrosine kinase inhibitors to improve outcomes in GIST ⬇️

scientific article published on February 20, 2012

Effect of aspirin on cancer incidence and mortality in older adults

scientific article published on 11 August 2020

Enhancement of platelet recovery after myelosuppressive chemotherapy by recombinant human megakaryocyte growth and development factor in patients with advanced cancer

scientific article

Enough is enough … a call to action to improve ethical and governance review processes in Australia

scientific article

Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

scientific article published on December 2005

Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer

scientific article published on 12 December 2013

Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer

scientific article published on 04 September 2019

Evaluation of efficacy and safety markers in a phase II study of metastatic colorectal cancer treated with aflibercept in the first-line setting

scientific article

Expanded low allele frequency RAS and BRAF V600E testing in metastatic colorectal cancer as predictive biomarkers for cetuximab in the randomized CO.17 trial

scientific article published on 21 October 2020

Exploring patient-reported outcomes following percutaneous coronary intervention: A qualitative study

scientific article published on 12 November 2017

Expression of mdr1 and mrp in the normal B-cell homologue of B-cell chronic lymphocytic leukaemia

scientific article published on 01 March 1997

FDG-PET follow up of Non-Small Cell Lung Cancer: Not dead yet

scientific article published on 06 July 2019

Fc-γ Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.

scientific article

Feasibility of 5-fluorouracil pharmacokinetic monitoring using the My-5FU PCM™ system in a quaternary oncology centre

scientific article published on 03 September 2018

Final results of a randomised trial comparing 'Tomudex' (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer

scientific article published in November 1996

Gastric cancer: past progress and present challenges

scientific article published on 26 October 2014

Health-related quality of life in patients with advanced colorectal cancer treated with cetuximab: overall and KRAS-specific results of the NCIC CTG and AGITG CO.17 Trial

scientific article published on 9 March 2009

Highlights of the EORTC St. Gallen International Expert Consensus on the primary therapy of gastric, gastroesophageal and oesophageal cancer - differential treatment strategies for subtypes of early gastroesophageal cancer.

scientific article published on 23 August 2012

Individual patient data analysis of progression-free survival versus overall survival as a first-line end point for metastatic colorectal cancer in modern randomized trials: findings from the analysis and research in cancers of the digestive system d

scientific article published in January 2015

Intrigue: Phase III study of ripretinib versus sunitinib in advanced gastrointestinal stromal tumor after imatinib

scientific article published on 22 November 2019

Is improving local control sufficient indication for radiotherapy in the management of rectal cancer? A response

scientific article published on 01 August 2003

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

scientific article

KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

scientific article

Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17.

scientific article published on 12 May 2015

Medical education in palliative care ⬇️

scientific article published on 01 January 1990

Medical paternalism and expensive unsubsidised drugs

scientific article

Modification of leucovorin dose within a simplified FOLFOX regimen improves tolerability without compromising efficacy

scientific article published on 01 July 2007

Modulation of the function of human MDR1 P-glycoprotein by the antimalarial drug mefloquine.

scientific article published on November 1996

Monitoring quality of care for patients with pancreatic cancer: a modified Delphi consensus

scientific article published on 11 October 2018

NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines.

scientific article published on July 2007

Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial

scientific article published on 31 January 2018

Not‐for‐resuscitation orders in cancer patients — principles of decision‐making ⬇️

scientific article published on August 20, 1990

Optimum Tools for Predicting Clinical Outcomes in Prostate Cancer Patients Undergoing Radical Prostatectomy: A Systematic Review of Prognostic Accuracy and Validity

scientific article published on 8 June 2017

Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg.

scientific article

PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer--results from NCIC CTG/AGITG CO.17.

scientific article

Palifermin reduces the incidence of oral mucositis in patients with metastatic colorectal cancer treated with fluorouracil-based chemotherapy

scientific article published on 30 October 2006

Palliative chemotherapy: a clinical oxymoron

scientific article

Patient-Reported Outcomes After Radiation Therapy in Men With Prostate Cancer: A Systematic Review of Prognostic Tool Accuracy and Validity

scientific article published on 21 February 2017

Patient-reported outcome measures (PROMs) in pancreatic cancer: a systematic review

scientific article published on 18 October 2019

Patients' beliefs about cancer management

scientific article published in March 1996

Peeling the Onion of Health Care Disparity in Lung Cancer

scientific article published on 01 August 2019

Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project

Phase I trial of docetaxel, cisplatin and concurrent radical radiotherapy in locally advanced oesophageal cancer

scientific article

Phase III randomized, placebo-controlled study of cetuximab plus brivanib alaninate versus cetuximab plus placebo in patients with metastatic, chemotherapy-refractory, wild-type K-RAS colorectal carcinoma: the NCIC Clinical Trials Group and AGITG CO

scientific article

Physical mapping of a tandem duplication on the long arm of chromosome 7 associated with a multidrug resistant phenotype.

scientific article published on April 1999

Pre- and Postoperative Capecitabine Without or With Oxaliplatin in Locally Advanced Rectal Cancer: PETACC 6 Trial by EORTC GITCG and ROG, AIO, AGITG, BGDO, and FFCD

scientific article published on 01 October 2020

Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

scientific article

Preoperative cisplatin, fluorouracil, and docetaxel with or without radiotherapy after poor early response to cisplatin and fluorouracil for resectable oesophageal adenocarcinoma (AGITG DOCTOR): results from a multicentre, randomised controlled phas

scientific article published on 23 December 2019

Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial

scientific article

Prospective cost-effectiveness analysis of cetuximab in metastatic colorectal cancer: evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 trial

scientific article published on 7 August 2009

Quality of life in patients with K-RAS wild-type colorectal cancer: the CO.20 phase 3 randomized trial

scientific article published on 11 October 2013

Randomized trial of coordinated psychosocial interventions based on patient self-assessments versus standard care to improve the psychosocial functioning of patients with cancer

scientific article

Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04.

scientific article

Rapid functional assay for multidrug resistance in human tumor cell lines using the fluorescent indicator fluo-3

scientific article published on 01 February 1991

Real-world data for health technology assessment for reimbursement decisions in Asia: current landscape and a way forward

scientific article published on 15 September 2020

Real-world treatment patterns, healthcare resource use and clinical outcomes of patients receiving second line therapy for advanced or metastatic gastric cancer

scientific article published on 05 May 2020

Recent Advances in the Systemic Therapy of Metastatic Colorectal Cancer

Recent developments in the systemic therapy of advanced gastroesophageal malignancies

scientific article

Rectal cancer in Victoria in 1994: Patterns of reported management

article

Reducing clinical trial monitoring resource allocation and costs through remote access to electronic medical records

scientific article published on January 2013

Registry of gastric cancer treatment evaluation (REGATE): I baseline disease characteristics

scientific article

Registry of gastric cancer treatment evaluation (REGATE): II treatment practice

scientific article published on 5 August 2013

Regorafenib for the Treatment of Advanced Gastric Cancer (INTEGRATE): A Multinational Placebo-Controlled Phase II Trial

scientific article published on 20 June 2016

Regorafenib in gastrointestinal stromal tumors: clinical evidence and place in therapy

scientific article

Regorafenib plus modified FOLFOX6 as first-line treatment of metastatic colorectal cancer: A phase II trial.

scientific article published on 25 March 2015

Regulation of MDR1 gene expression: emerging concepts.

scientific article

Relationship of Hepatic Functional Imaging to Irinotecan Pharmacokinetics and Genetic Parameters of Drug Elimination

article

Ripretinib in patients with advanced gastrointestinal stromal tumours (INVICTUS): a double-blind, randomised, placebo-controlled, phase 3 trial

scientific article published on 05 June 2020

Role of palifermin in fluorouracil-based therapy for metastatic colorectal cancer

scientific article published in March 2008

Safety and tolerability of veliparib combined with capecitabine plus radiotherapy in patients with locally advanced rectal cancer: a phase 1b study

scientific article published on 27 March 2017

Sequential extraction of DNA and DNA-binding proteins from low cell numbers.

scientific article published on April 1997

Short-term outcome of emergency colorectal cancer surgery: results from Bi-National Colorectal Cancer Audit

scientific article published on 30 September 2018

Signal therapy of breast cancers by the HDAC inhibitor FK228 that blocks the activation of PAK1 and abrogates the tamoxifen-resistance

scientific article

Single-agent irinotecan or FOLFIRI as second-line chemotherapy for advanced colorectal cancer; results of a randomised phase II study (DaVINCI) and meta-analysis [corrected].

scientific article published on 12 June 2011

Soft tissue metastasis of carcinoid tumour: a rare manifestation

scientific article published on 01 March 2004

Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial.

scientific article published in September 2005

Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis.

scientific article

Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: a meta-analysis.

scientific article

Symptoms and feelings valued by patients after a percutaneous coronary intervention: a discrete-choice experiment to inform development of a new patient-reported outcome

scientific article published on 18 October 2018

TACTIC: a multicentre, open-label, single-arm phase II trial of panitumumab, cisplatin, and gemcitabine in biliary tract cancer

scientific article published on 22 June 2016

TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG.

scientific article published on 23 March 2017

TOPGEAR: a randomised phase III trial of perioperative ECF chemotherapy versus preoperative chemoradiation plus perioperative ECF chemotherapy for resectable gastric cancer (an international, intergroup trial of the AGITG/TROG/EORTC/NCIC CTG).

scientific article published on 21 July 2015

Telehealth

scientific article published on 25 January 2018

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointesti

scientific article published on 31 March 2017

The Victorian Lung Cancer Service Redesign Project: Impacts of a Quality Improvement collaborative on timeliness and management in lung cancer

scientific article published on 08 September 2020

The acceleration of ageing in older patients with cancer

scientific article published on 12 September 2020

The cost effectiveness of bevacizumab when added to capecitabine, with or without mitomycin-C, in first line treatment of metastatic colorectal cancer: results from the Australasian phase III MAX study

scientific article published on 8 November 2013

The impact on health-related quality of life in the first 12 months: A randomised comparison of preoperative short-course radiation versus long-course chemoradiation for T3 rectal cancer (Trans-Tasman Radiation Oncology Group Trial 01.04).

scientific article

The optimal 5-fluorouracil regimen for the adjuvant therapy of colon cancer: where to from here?

scientific article published on 01 August 2000

The pure antiestrogen ICI 182,780 binds to a high‐affinity site distinct from the estrogen receptor ⬇️

scientific article published on August 9, 1995

The relationship between rash, tumour KRAS mutation status and clinical and quality of life outcomes in patients with advanced colorectal cancer treated with cetuximab in the NCIC CTG/AGITG CO.17.

scientific article published on 5 February 2014

The role of 5-fluorouracil dose in the adjuvant therapy of colorectal cancer

scientific article published on 01 January 1996

Time to Definitive Failure to the First Tyrosine Kinase Inhibitor in Localized GI Stromal Tumors Treated With Imatinib As an Adjuvant: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Intergroup Randomi

scientific article published on 16 November 2015

To Tell or Not to Tell: The Community Wants to Know About Expensive Anticancer Drugs As a Potential Treatment Option

scientific article published on 28 September 2009

Tools for Predicting Clinical and Patient-reported Outcomes in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy: A Systematic Review of Prognostic Accuracy and Validity

scientific article

Towards a strategy for clinical quality registries in Australia

scientific article published on 8 February 2018

Understanding and Communicating Measures of Treatment Effect on Survival: Can We Do Better?

scientific article published on 01 March 2018

Views of Australian Medical Oncologists Regarding the Use of Mismatch Repair Status to Assist Adjuvant Chemotherapy Recommendations for Patients With Early-Stage Colon Cancer

scientific article

What constitutes a multidisciplinary team meeting?

scientific article

ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. Tomudex Colorectal Study Group

scientific article published in March 1996

‘Tomudex’ (ZD1694): Results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia

scientific article published in November 1995

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