List of works by David C Linch

A Megakaryocytic Thrombocytopenia Associated with an Excess of Leu 2a+ Suppressor Cells

scientific article published on March 1, 1982

A case of EBV-associated lymphoproliferative disease following high-dose therapy and CD34-purified autologous peripheral blood progenitor cell transplantation

scientific article published on 01 August 1998

A chronic myeloproliferative disorder associated with monosomy 7 in the bone marrow cells; normal karyotype in acute transformation

scientific article published on 01 July 1982

A clinically applicable method for the ex vivo generation of antigen-presenting cells from CD34+ progenitors

scientific article published on 01 January 2000

A comparison of the outcome of ABMT in first remission acute myeloid and lymphoblastic leukemia in a single centre

scientific article published on July 1990

A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy

scientific article published on 26 June 2014

A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications

scientific article published on 01 January 1999

A phase III trial comparing CHOP to PMitCEBO with or without G-CSF in patients aged 60 plus with aggressive non-Hodgkin's lymphoma

scientific article published on March 2006

A randomised comparison of a third-generation regimen (PACEBOM) with a standard regimen (CHOP) in patients with histologically aggressive non-Hodgkin's lymphoma: a British National Lymphoma Investigation report

scientific article

A randomized British National Lymphoma Investigation trial of CHOP vs. a weekly multi-agent regimen (PACEBOM) in patients with histologically aggressive non-Hodgkin's lymphoma

scientific article published in 2000

A response-adjusted PET-based transplantation strategy in primary resistant and relapsed Hodgkin Lymphoma.

scientific article published on 8 November 2012

A retrospective comparison of toxicity and initial efficacy of two autologous stem cell transplant conditioning regimens for relapsed lymphoma: LEAM and BEAM

scientific article published on 23 May 2016

A review of gene therapy for haematological disorders

scientific article

A rise in the percentage of large unstained cells in the peripheral blood determined by the Hemalog D90 automated differential counter is a feature of impending myeloid engraftment following bone marrow transplantation

scientific article published on 01 January 1986

A second autologous transplant may be efficacious in selected patients with Hodgkin's lymphoma relapsing after a previous autograft

scientific article published on 01 May 2007

A study to determine whether trisomy 8, deleted 9q and trisomy 22 are markers of cryptic rearrangements of PML/RARalpha, AML1/ETO and CBFB/MYH11 respectively in acute myeloid leukaemia. MRC Adult Leukaemia Working Party. Medical Research Council

scientific article published in May 1998

A truncated isoform of the human beta chain common to the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 with increased mRNA expression in some patients with acute leukemia

scientific article published on 01 January 1998

ASXL1 mutations are infrequent in young patients with primary acute myeloid leukemia and their detection has a limited role in therapeutic risk stratification

scientific article published on 9 October 2013

Abnormalities of T-cell subsets in patients with neutropenia and an excess of lymphocytes in the bone marrow

scientific article published on 01 May 1981

Accessory cells do not contribute to G-CSF or IL-6 production nor to rapid haematological recovery following peripheral blood stem cell transplantation

scientific article published on 01 November 1995

Acquired pure red-cell aplasia associated with an increase of T cells bearing receptors for the Fc of IgG

scientific article published on 01 January 1981

Acquired skewing of X-chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age.

scientific article

Activating point mutations in the betaC chain of the GM-CSF, IL-3 and IL-5 receptors are not a major contributory factor in the pathogenesis of acute myeloid leukaemia

scientific article published on 01 October 1998

Activation and priming of neutrophil nicotinamide adenine dinucleotide phosphate oxidase and phospholipase A(2) are dissociated by inhibitors of the kinases p42(ERK2) and p38(SAPK) and by methyl arachidonyl fluorophosphonate, the dual inhibitor of c

scientific article published in April 2001

Activation of human monocytes occurs on cross-linking monocytic antigens to an Fc receptor

scientific article published on 01 April 1989

Activation of monocytic cells by monoclonal antibodies to the CD11a/18 (LFA-1) complex: mediation by Fc receptor

scientific article published on April 1990

Activation of phospholipase A2 during differentiation of human haemopoietic progenitor cells

scientific article published on 01 August 1998

Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia.

scientific article published on 7 March 2017

Acute hepatitis C infection in patients undergoing therapy for haematological malignancies: a clinical and virological study

scientific article published in March 1993

Acute myeloid leukaemia blast cells with a tyrosine kinase domain mutation of FLT3 are less sensitive to lestaurtinib than those with a FLT3 internal tandem duplication

scientific article

Acute myeloid leukaemia.

scientific article published on 10 March 2016

Acute-phase response in patients given rhIL-3 after chemotherapy

article published in 1992

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

scientific article published on 10 December 2011

Allo-HSCT in transplant-naïve patients with Hodgkin lymphoma: a single-arm, multicenter study

scientific article published on 01 December 2019

Allogeneic transplantation for hepatosplenic alphabeta T-cell lymphoma

scientific article published on 01 May 2005

Amplification of mitochondrial DNA in acute myeloid leukaemia

scientific article published on 01 November 1996

An activating mutation in the transmembrane domain of the granulocyte colony-stimulating factor receptor in patients with acute myeloid leukemia

scientific article

An intracellular 50-kDa Fc gamma-binding protein is induced in human cells by alpha-IFN

scientific article published on 01 March 1991

Analysis of granulocyte colony stimulating factor receptor isoforms, polymorphisms and mutations in normal haemopoietic cells and acute myeloid leukaemia blasts

scientific article published on 01 June 1996

Analysis of mutations in the GM-CSF receptor alpha coding sequence in patients with acute myeloid leukaemia and haematologically normal individuals by RT-PCR-SSCP

scientific article published on 01 September 1994

Analysis of the clinical impact of NPM1 mutant allele burden in a large cohort of younger adult patients with acute myeloid leukaemia

scientific article published on 08 October 2019

Analysis of the coding sequence for the GM-CSF receptor alpha and beta chains in patients with juvenile chronic myeloid leukemia (JCML).

scientific article

Another look at follicular lymphoma: immunophenotypic and molecular analyses identify distinct follicular lymphoma subgroups

scientific article published on 20 March 2013

Assessment of Minimal Residual Disease in Standard-Risk AML.

scientific article

Assessment of X-chromosome inactivation patterns using the hypervariable probe M27 beta in normal hemopoietic cells and acute myeloid leukemic blasts

scientific article published on 01 July 1992

Attempted bone-marrow transplantation in a 17-week fetus

scientific article

Autologous Bone-Marrow Transplantation in Acute Lymphoblastic Leukaemia: 1980-89

scientific article published on 01 January 1990

Autologous bone marrow transplantation

scientific article published on 01 September 1984

Autologous bone marrow transplantation following high dose chemotherapy for the treatment of adult patients with acute myeloid leukaemia

scientific article published on 01 November 1986

Autologous bone marrow transplantation for acute leukaemia in remission

scientific article published on 01 October 1986

Autologous bone marrow transplantation for patients with acute myeloid leukaemia and acute lymphoblastic leukaemia--a comparison

scientific article published on 01 February 1987

Autologous bone marrow transplantation in acute leukaemia

scientific article

Autologous stem cell transplantation for follicular lymphoma is of most benefit early in the disease course and can result in durable remissions, irrespective of prior rituximab exposure

scientific article published on 18 January 2014

Autologous stem cell transplantation outcomes in elderly patients with B cell Non-Hodgkin Lymphoma.

scientific article published on 26 June 2015

Autologous stem cell transplantation remains beneficial for patients relapsing after R-CHOP chemotherapy and who respond to salvage chemotherapy

scientific article published on 16 August 2011

BEAM chemotherapy and autologous bone marrow transplantation for patients with relapsed or refractory non-Hodgkin's lymphoma.

scientific article published in March 1995

BRAF V600E mutation-specific antibody, a sensitive diagnostic marker revealing minimal residual disease in hairy cell leukaemia

scientific article published on 13 July 2013

BRAF(V600E) mutations are found in Richter syndrome and may allow targeted therapy in a subset of patients.

scientific article published on 10 March 2015

Back-up bone marrow is frequently ineffective in patients with poor peripheral-blood stem-cell mobilization

scientific article published on 01 April 1998

Binding of monoclonal antibody to CD16 causes calcium mobilization in large granular lymphocytes but inhibits NK killing

scientific article published on 01 March 1989

Bone marrow T cell colony-forming cells: studies of their origin and use in monitoring T cell-depleted bone marrow grafts

scientific article published on 01 December 1985

Breast cancer risk after supradiaphragmatic radiotherapy for Hodgkin's lymphoma in England and Wales: a National Cohort Study

scientific article published on 25 June 2012

Breast cancer risk following Hodgkin lymphoma radiotherapy in relation to menstrual and reproductive factors

scientific article published on 07 May 2013

Burkitt lymphoma in adults

scientific article published on 19 September 2011

CD2 and CD3 antigens mobilize Ca2+ independently

scientific article published on 01 May 1986

Caution in the Use of Immunohistochemistry for Determination of Cell of Origin in Diffuse Large B-Cell Lymphoma.

scientific article

Cell cycle status in AML blast cells from peripheral blood, bone marrow aspirates and trephines and implications for biological studies and treatment.

scientific article published on 8 April 2016

Central nervous system chemoprophylaxis in non-Hodgkin lymphoma: current practice in the UK.

scientific article

Central nervous system relapse of diffuse large B-cell lymphoma in the rituximab era: results of the UK NCRI R-CHOP-14 versus 21 trial.

scientific article published in October 2017

Changes in signal transduction downstream from the granulocyte-macrophage colony-stimulating factor receptor during differentiation of primary hemopoietic cells

scientific article published on 01 June 1999

Characterization of cell cycle status and E2F complexes in mobilized CD34+ cells before and after cytokine stimulation

scientific article published on 01 July 1997

ChlVPP alternating with PABlOE is superior to PABlOE alone in the initial treatment of advanced Hodgkin's disease: results of a British National Lymphoma Investigation/Central Lymphoma Group randomized controlled trial

scientific article

Chlorambucil versus observation after anti-Helicobacter therapy in gastric MALT lymphomas: results of the international randomised LY03 trial

scientific article

Chronic T cell lymphocytosis: a review of 21 cases.

scientific article

Clinical Applications of Haemopoietic Growth Factors

scientific article published on January 1, 1992

Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation

scientific article published in June 2005

Clinical significance of the haemopoietic growth factors

scientific article published in January 1989

Clinical stage 1 non-Hodgkin's lymphoma: long-term follow-up of patients treated by the British National Lymphoma Investigation with radiotherapy alone as initial therapy

scientific article

Clinical studies of ABMT in acute myeloid leukaemia

scientific article

Clonality studies in acute myeloid leukemia

scientific article published on February 1998

Comparison of CHOP versus CIOP in good prognosis younger patients with histologically aggressive non-Hodgkin lymphoma

scientific article published in August 2005

Comparison of PET/MRI With PET/CT in the Evaluation of Disease Status in Lymphoma

scientific article published on 7 September 2016

Comparison of the sensitivity of normal and leukaemic myeloid progenitors to in-vitro incubation with cytotoxic drugs: a study of pharmacological purging

scientific article published on 01 January 1987

Conflicting data on the prognostic significance of FLT3/TKD mutations in acute myeloid leukemia might be related to the incidence of biallelic disease

scientific article published in July 2008

Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia

scientific article

Conventional second-line salvage chemotherapy regimens are not warranted in patients with malignant lymphomas who have progressive disease after first-line salvage therapy regimens

scientific article published on 01 August 2005

Cord blood progenitor cells have greater transendothelial migratory activity and increased responses to SDF-1 and MIP-3beta compared with mobilized adult progenitor cells

scientific article published on 01 November 1999

Crossover study of the haematological effects and pharmacokinetics of glycosylated and non‐glycosylated G‐CSF in healthy volunteers

scientific article published on 01 August 1997

Cyclin C is a haploinsufficient tumour suppressor

scientific article

Cytopenia and T cell proliferation

scientific article published on 01 July 1982

De novo treatment of diffuse large B-cell lymphoma with rituximab, cyclophosphamide, vincristine, gemcitabine, and prednisolone in patients with cardiac comorbidity: a United Kingdom National Cancer Research Institute trial.

scientific article published on 12 November 2013

Debate on the conservative and aggressive treatment options for the optimal management of indolent non-Hodgkinʼs lymphoma

scientific article published on November 1, 2002

Delayed neutrophil recovery after BEAM chemotherapy and autologous bone marrow transplantation for lymphoma is not associated with increased mortality from infection

scientific article published on 01 February 1995

Demonstration of developing myelodysplasia/acute myeloid leukaemia in haematologically normal patients after high-dose chemotherapy and autologous bone marrow transplantation using X-chromosome inactivation patterns

scientific article published on 01 April 1996

Desirability and problems of early diagnosis of essential thrombocythaemia

scientific article published on 01 March 1998

Detection and significance of bone marrow infiltration at the time of autologous bone marrow transplantation in Hodgkin's disease

scientific article published on 01 July 1994

Detection and significance of pulmonary Hodgkin's disease at autologous bone marrow transplantation

scientific article published on 01 February 1994

Detection of leukemia-associated mutations in peripheral blood DNA of hematologically normal elderly individuals

scientific article published on 28 January 2015

Development of a simplified single-apheresis approach for peripheral-blood progenitor-cell transplantation in previously treated patients with lymphoma

scientific article published on 01 August 1994

Development of antibodies to unprotected glycosylation sites on recombinant human GM-CSF

scientific article published on 01 February 1990

Developments in the management of Hodgkin's lymphoma

scientific article published on 18 February 2010

Developments over the last 60 years in diffuse large B-cell lymphomas

scientific article published on 01 November 2020

Different levels of p38 MAP kinase activity mediate distinct biological effects in primary human erythroid progenitors

scientific article

Different pathways of human T-cell activation revealed by PHA-P and PHA-M

scientific article published on 01 January 1986

Differential effects of granulocyte‐ and granulocyte‐macrophage colony‐stimulating factors (G‐ and GM‐CSF) on neutrophil adhesion in vitro and in vivo

scientific article published on 01 November 1992

Differential phthalocyanine photosensitization of acute myeloblastic leukaemia progenitor cells: a potential purging technique for autologous bone marrow transplantation

scientific article published on 01 April 1988

Differentiation-linked activation of the respiratory burst in a monocytic cell line (U937) via Fc gamma RII. A study of activation pathways and their regulation

scientific article published on November 1, 1991

Differentiation-linked changes in granulocyte-macrophage colony-stimulating factor receptor mediated signalling in the HL-60 promyelocytic cell line

scientific article published on April 1998

Differentiation-linked changes in tyrosine phosphorylation, functional activity, and gene expression downstream from the granulocyte-macrophage colony-stimulating factor receptor

scientific article published on August 1994

Does BCR/ABL1 positive acute myeloid leukaemia exist?

scientific article published on 25 March 2013

Donor lymphocyte infusions modulate relapse risk in mixed chimeras and induce durable salvage in relapsed patients after T-cell-depleted allogeneic transplantation for Hodgkin's lymphoma.

scientific article

Dose intensification of etoposide in the BEAM ABMT protocol for malignant lymphoma

scientific article published on 01 April 1995

Dose intensification with autologous bone-marrow transplantation in relapsed and resistant Hodgkin's disease: results of a BNLI randomised trial

scientific article

Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: toxicity, chimerism, and disease responses.

scientific article published on 23 October 2003

Double autografting in first remission acute myeloid leukaemia

scientific article published on 01 January 1989

Double autologous bone marrow transplantation in acute myeloid leukaemia

scientific article published on 01 January 1989

Down-regulation of human protein kinase C alpha is associated with terminal neutrophil differentiation

scientific article published on July 1, 1992

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia

scientific article published on 24 March 2015

Dynamic modulation of the cell surface expression of the granulocyte-macrophage colony-stimulating factor receptor

scientific article published on September 1993

Dynamics of telomere shortening in neutrophils and T lymphocytes during ageing and the relationship to skewed X chromosome inactivation patterns

scientific article published on 01 May 2000

ESHAP and G-CSF is a superior blood stem cell mobilizing regimen compared to cyclophosphamide 1.5 g m(-2) and G-CSF for pre-treated lymphoma patients: a matched pairs analysis of 78 patients

scientific article published on January 2000

EVI1 expression in acute myeloid leukaemia

scientific article published on 01 January 2001

EZH2 deficient T-cell acute lymphoblastic leukemia is sensitized to CHK1 inhibition through enhanced replication stress

scientific article published on 29 April 2020

Economic analysis of a randomized clinical trial to compare filgrastim-mobilized peripheral-blood progenitor-cell transplantation and autologous bone marrow transplantation in patients with Hodgkin's and non-Hodgkin's lymphoma

scientific article published in January 1997

Effect of changes in expression of the amphotropic retroviral receptor PiT-2 on transduction efficiency and viral titer: implications for gene therapy

scientific article published on March 2000

Effectiveness of high-dose combination chemotherapy and autologous bone marrow transplantation for patients with non-Hodgkin's lymphomas who are still responsive to conventional-dose therapy

scientific article published on 01 November 1989

Efficacy of delayed granulocyte colony-stimulating factor after autologous BMT

scientific article published on 01 June 1993

Electrophoretic and cytochemical characterization of alpha-naphthyl acetate esterases in acute myeloid leukemia: relationships with membrane receptor and monocyte-specific antigen expression

scientific article published on March 1, 1984

Engraftment defect of cytokine-cultured adult human mobilized CD34(+) cells is related to reduced adhesion to bone marrow niche elements

scientific article

Enhanced fluorescence in indirect immunophenotyping by the use of fluorescent liposomes

scientific article published on 01 July 1989

Evaluation of clinical scale CD34+ cell purification: experience of 71 immunoaffinity column procedures

scientific article published on 01 July 1997

Excessive T cell depletion of peripheral blood stem cells has an adverse effect upon outcome following allogeneic stem cell transplantation

scientific article published on 01 November 2001

Expression and dynamic modulation of the human granulocyte colony-stimulating factor receptor in immature and differentiated myeloid cells

scientific article published on October 1993

Expression of two alternatively spliced forms of the 5' untranslated region of the GM-CSF receptor alpha chain mRNA

scientific article published on 01 May 1996

Extended routine polymerase chain reaction surveillance and pre-emptive antiviral therapy for cytomegalovirus after allogeneic transplantation

scientific article published on 01 December 2000

FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia

scientific article published on 24 April 2007

Factors affecting survival in patients aged 60 and over with diffuse large B cell lymphoma failing first-line therapy

scientific article

Failure of IMVP-16 as second-line treatment for relapsed or refractory high grade non-Hodgkin's lymphoma

scientific article published on March 1, 1992

Failure of embryonic mouse cells to engraft in immunocompetent allogeneic recipients

scientific article published on 01 April 1990

Favorable long-term survival after reduced-intensity allogeneic transplantation for multiple-relapse aggressive non-Hodgkin's lymphoma

scientific article published on 8 December 2008

Favourable Outcomes for High-Risk Diffuse Large B-Cell Lymphoma (IPI 3-5) Treated with Front-Line R-CODOX-M/R-IVAC Chemotherapy: Results of a Phase 2 UK NCRI Trial

scientific article published on 25 May 2020

Fc gamma RII, but not erythropoietin or GM-CSF, mediates calcium mobilization in fetal hemopoietic blast cells

scientific article published on March 1, 1992

Fc gamma RII-mediated superoxide production by phagocytes is augmented by GM-CSF without a change in Fc gamma RII expression.

scientific article published in September 1990

Feasibility of multidrug resistance (MDR-1) gene transfer in patients undergoing high-dose therapy and peripheral blood stem cell transplantation for lymphoma

scientific article published in March 1998

Fetal haemopoietic cells display enhanced migration across endothelium

scientific article published on 01 February 2002

Final analysis of the UKLG LY02 trial comparing 6-8 cycles of CHOP with 3 cycles of CHOP followed by a BEAM autograft in patients <65 years with poor prognosis histologically aggressive NHL.

scientific article published in March 2010

Flt3 mutations and leukaemia

scientific article

Fludarabine, adriamycin and dexamethasone (FAD) in newly diagnosed advanced follicular lymphoma: a phase II study by the British National Lymphoma Investigation (BNLI)

scientific article published on August 2004

Frequency of CBF beta/MYH11 fusion transcripts in patients entered into the U.K. MRC AML trials. The MRC Adult Leukaemia Working Party

scientific article published on 01 March 1997

Frequency of clonal remission in acute myeloid leukaemia

scientific article published on 01 January 1993

G-CSF after peripheral blood stem cell transplantation in lymphoma patients significantly accelerated neutrophil recovery and shortened time in hospital: results of a randomized BNLI trial

scientific article published on 01 December 1997

G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction

scientific article

GATA2 mutations in sporadic and familial acute myeloid leukaemia patients with CEBPA mutations

scientific article published on 5 April 2013

GM-CSF accelerates neutrophil recovery after autologous bone marrow transplantation for Hodgkin's disease

scientific article published on 01 January 1989

Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients

scientific article published on 04 January 2019

Germ cell damage and Leydig cell insufficiency in recipients of nonmyeloablative transplantation for haematological malignancies

scientific article published on January 2003

Glutathione S-transferase theta 1 (GSTT1) gene defect in myelodysplasia and acute myeloid leukaemia

scientific article published on 01 May 1997

Granulocyte macrophage colony stimulating factor induced changes in cellular adhesion molecule expression and adhesion to endothelium: in-vitro and in-vivo studies in man

scientific article published on 01 March 1989

Granulocyte-macrophage colony stimulating factor receptor alpha and beta chain complexes can form both high and intermediate affinity functional receptors.

scientific article published on September 1997

Granulocyte-macrophage colony-stimulating factor may inhibit neutrophil migration in vivo

scientific article published on 01 May 1989

Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.

scientific article published in September 2001

Guideline on the management of primary resistant and relapsed classical Hodgkin lymphoma

scientific article published on 01 October 2013

Guidelines for the first line management of classical Hodgkin lymphoma

scientific article published on 09 April 2014

Gynaecomastia with hypergonadotrophic hypogonadism and Leydig cell insufficiency in recipients of high-dose chemotherapy or chemo-radiotherapy

scientific article published in December 2001

Gö6976 is a potent inhibitor of the JAK 2 and FLT3 tyrosine kinases with significant activity in primary acute myeloid leukaemia cells

scientific article published on 4 September 2006

HLA-mismatched unrelated donors are a viable alternate graft source for allogeneic transplantation following alemtuzumab-based reduced-intensity conditioning

scientific article published on 6 April 2010

High Response Rate to Donor Lymphocyte Infusion after Allogeneic Stem Cell Transplantation for Indolent Non-Hodgkin Lymphoma

scientific article published on 01 January 2008

High incidence of Notch-1 mutations in adult patients with T-cell acute lymphoblastic leukemia

scientific article published on 01 March 2006

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution

scientific article published on 01 June 2002

High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.

scientific article published on October 1999

High-dose chemotherapy and autologous bone marrow transplantation in acute myeloid leukemia

scientific article published on 01 August 1990

High-dose cyclophosphamide with autologous marrow transplantation as initial treatment of small cell carcinoma of the bronchus

scientific article published on 01 January 1982

High-dose cyclophosphamide with autologous marrow transplantation for small cell carcinoma of the bronchus

scientific article published on 01 January 1983

High-dose therapy and autologous stem-cell transplantation for adult patients with Hodgkin's disease who do not enter remission after induction chemotherapy: results in 175 patients reported to the European Group for Blood and Marrow Transplantation

scientific article published on 01 October 1999

High-dose therapy for Hodgkin's disease

scientific article

Hodgkin's Lymphoma: Choice of Therapy and Late Complications.

scientific article

Hodgkin's lymphoma

scientific article published on 01 March 2003

Hodgkin's lymphoma in adults

scientific article

Hodgkin-cell leukaemia of B-cell origin

scientific article published on 01 January 1985

Homozygous HAX1 mutations in severe congenital neutropenia patients with sporadic disease: a novel mutation in two unrelated British kindreds

scientific article published on 22 November 2008

Human Leucocyte antigens

scientific article published on 01 January 1981

Hybrid LOPP/EVA is not better than LOPP alternating with EVAP: a prematurely terminated British National Lymphoma Investigation randomized trial.

scientific article published on January 1994

Identification of the t(15;17) in AML FAB types other than M3: evaluation of the role of molecular screening for the PML/RARalpha rearrangement in newly diagnosed AML. The Medical Research Council (MRC) Adult Leukaemia Working Party

scientific article

Immune guided missiles

scientific article published on September 1982

Immunophenotypic analysis of cell cycle status in acute myeloid leukaemia: relationship to cytogenetics, genotype and clinical outcome.

scientific article published on 20 April 2018

Impact of FLT3(ITD) mutant allele level on relapse risk in intermediate-risk acute myeloid leukemia.

scientific article

Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial.

scientific article published on 3 July 2012

Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial

scientific article

Impact of high-dose salvage therapy (BEAM) on overall survival in younger patients with advanced large-cell lymphomas entered into BNLI trials

scientific article published on 01 January 1997

Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model.

scientific article published on 20 November 2003

Improved intensive care unit survival for critically ill allogeneic haematopoietic stem cell transplant recipients following reduced intensity conditioning

scientific article

In essential thrombocythemia, multiple JAK2-V617F clones are present in most mutant-positive patients: a new disease paradigm.

scientific article published on 18 June 2009

In trans early mosaic mutational escape and novel phenotypic features of germline SAMD9 mutation

scientific article published on 03 January 2020

In vivo CAMPATH-1H prevents GvHD following nonmyeloablative stem-cell transplantation

scientific article published in January 2001

In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation

scientific article published on 01 October 2000

In vivo effects of macrophage colony-stimulating factor on human monocyte function

scientific article published on 01 January 1991

Incidence and clinical importance of bone marrow eosinophilia in Hodgkin's disease (BNLI Report No 29). British National Lymphoma Investigation

scientific article

Incidence and outcome of adenovirus disease in transplant recipients after reduced-intensity conditioning with alemtuzumab

scientific article published in March 2004

Incidence and prognostic significance of C-MPL expression in acute myeloid leukemia

scientific article published on 01 September 2003

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials. MRC Adult Leukaemia Working Party

scientific article published on 01 December 1997

Influence of cell cycling and cell division on transendothelial migration of CD34+ cells.

scientific article published in November 2002

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

scientific article published on September 2008

Interactions between prostacyclin analogue ZK 36374 and heparin in their effects upon platelet function

scientific article published on 01 March 1987

Interactions of granulocyte-macrophage colony-stimulating factor (CSF), granulocyte CSF, and tumor necrosis factor alpha in the priming of the neutrophil respiratory burst

scientific article published on 01 February 1992

Interleukin-3 administration enhances human monocyte function in vivo

scientific article published on 01 November 1994

Interpretation of X-chromosome inactivation patterns

scientific article published on 01 October 1994

Investigation of early T cell activation: analysis of the effect of specific antigen, interleukin 2 and monoclonal antibodies on intracellular free calcium concentration

scientific article published on 01 January 1985

Investigation of methylation at Hha I sites using the hypervariable probe M27 beta allows improved clonal analysis in myeloid leukaemia and demonstrates differences in methylation between leukaemic and remission samples

scientific article published on 01 January 1994

Isolation of human haematopoietic progenitor cells using monoclonal antibodies

scientific article published in Nature

Isoquinolinesulfonamide protein kinase inhibitors H7 and H8 enhance the effects of granulocyte-macrophage colony-stimulating factor (GM-CSE) on neutrophil function and inhibit GM-CSF receptor internalization

scientific article published on 01 September 1990

KIR gene haplotype: an independent predictor of clinical outcome in MDS patients

scientific article published on 19 October 2016

LOPP alternating with EVAP is superior to LOPP alone in the initial treatment of advanced Hodgkin's disease: results of a British National Lymphoma Investigation trial

scientific article published on 01 August 1992

Lack of effect of granulocyte-macrophage and granulocyte colony-stimulating factors on cultured human endothelial cells

scientific article published on April 15, 1991

Lack of effect of the human GM-CSF analog E21R on the survival of primary human acute myeloid leukemia cells

scientific article published on 30 December 2003

Lack of pathogenic mutations in the 5'-untranslated region of the thrombopoietin gene in patients with non-familial essential thrombocythaemia

scientific article published on 01 October 2001

Late mortality in young BNLI patients cured of Hodgkin's disease

scientific article published on January 1994

Leukaemia complicating treatment for Hodgkin's disease: the experience of the British National Lymphoma Investigation

scientific article

Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen

scientific article published in February 2002

Lineage involvement in chronic myeloproliferative disorders

scientific article published on 01 August 1994

Liposomal amphotericin B in the treatment of fungal infections in neutropenic patients: a single-centre experience of 133 episodes in 116 patients

scientific article published on 01 April 1994

Long term outcome in adolescents with Hodgkin's lymphoma: poor results using regimens designed for adults.

scientific article published in August 2004

Long-term effect of a watch and wait policy versus immediate systemic treatment for asymptomatic advanced-stage non-Hodgkin lymphoma: a randomised controlled trial

scientific article published in August 2003

Long-term follow-up of granulocyte colony-stimulating factor receptor mutations in patients with severe congenital neutropenia: implications for leukaemogenesis and therapy.

scientific article

Long-term follow-up of patients treated with radiotherapy alone for early-stage histologically aggressive non-Hodgkin's lymphoma

scientific article published on March 2004

Long-term results of a randomised trial of involved field radiotherapy vs extended field radiotherapy in stage I and II Hodgkin lymphoma

scientific article published on 01 February 2005

Long-term serial analysis of X-chromosome inactivation patterns and JAK2 V617F mutant levels in patients with essential thrombocythemia show that minor mutant-positive clones can remain stable for many years

scientific article published on 05 October 2006

Low-dose lenograstim is as effective as standard dose in shortening neutrophil engraftment time following myeloablative chemotherapy and peripheral blood progenitor cell rescue.

scientific article published on 13 April 2007

Lung cancer after Hodgkin's disease: a nested case-control study of the relation to treatment

scientific article published in March 2001

Lymphocytosis: is it leukaemia and when to treat

scientific article published on January 1988

Management of erectile dysfunction by combination therapy with testosterone and sildenafil in recipients of high-dose therapy for haematological malignancies

scientific article published in April 2002

Mechanism of human monocyte activation via the 40-kDa Fc receptor for IgG

scientific article published on 01 December 1988

Membrane Fc-IgG and C3b receptors on myeloid leukaemia cells: a comparison with cytoplasmic acid naphthyl acetate esterase cytochemistry

scientific article published on May 1, 1983

Microarray analysis of tumour antigen expression in presentation acute myeloid leukaemia

scientific article published on August 2005

Mini-BEAM followed by BEAM and ABMT for very poor risk Hodgkin's disease.

scientific article

Mini-BEAM is effective as a bridge to transplantation in patients with refractory or relapsed Hodgkin lymphoma who have failed to respond to previous lines of salvage chemotherapy but not in patients with salvage-refractory DLBCL

scientific article published on 20 March 2012

Mitoxantrone is superior to doxorubicin in a multiagent weekly regimen for patients older than 60 with high-grade lymphoma: results of a BNLI randomized trial of PAdriaCEBO versus PMitCEBO.

scientific article published in May 2001

Monoclonal antibodies differentiating between monocytic and nonmonocytic variants of AML.

scientific article

Monocyte-derived dendritic cells do not proliferate and are not susceptible to retroviral transduction

scientific article published on 01 March 2000

Most acute myeloid leukaemia patients with intermediate mutant FLT3/ITD levels do not have detectable bi-allelic disease, indicating that heterozygous disease alone is associated with an adverse outcome

scientific article published on 3 June 2008

Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party

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Mutations in the ELA2 gene encoding neutrophil elastase are present in most patients with sporadic severe congenital neutropenia but only in some patients with the familial form of the disease

scientific article published on 01 November 2001

Mutations of the AML1 gene in acute myeloid leukemia of FAB types M0 and M7.

scientific article published in May 2002

Mutations of the granulocyte-colony stimulating factor receptor in patients with severe congenital neutropenia are not required for transformation to acute myeloid leukaemia and may be a bystander phenomenon

scientific article published on 01 April 1998

Myocardial Infarction Mortality Risk After Treatment for Hodgkin Disease: A Collaborative British Cohort Study

scientific article published on 7 February 2007

Neurological complications following alemtuzumab-based reduced-intensity allogeneic transplantation

scientific article published in July 2004

Neutrophil elastase mutations in congenital neutropenia

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Next-generation sequencing identifies a novel ELAVL1-TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208.

scientific article published on 17 May 2016

No evidence that CD33 splicing SNP impacts the response to GO in younger adults with AML treated on UK MRC/NCRI trials

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No evidence that FLT3 status should be considered as an indicator for transplantation in acute myeloid leukemia (AML): an analysis of 1135 patients, excluding acute promyelocytic leukemia, from the UK MRC AML10 and 12 trials.

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No mutations in the GATA-1 gene detected in patients with acquired essential thrombocythemia

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Nonmyeloablative transplantation with or without alemtuzumab: comparison between 2 prospective studies in patients with lymphoproliferative disorders

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Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia

scientific article published on 01 December 2007

Novel markers in pediatric-type follicular lymphoma

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Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia

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Optimal timing for collection of PBPC after glycosylated G-CSF administration

scientific article published on 01 February 1998

Optimisation and quality control of cell processing for autologous stem cell transplantation

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Outcome of Elderly Patients with Diffuse Large B-cell Lymphoma Treated with R-CHOP: Results from the UK NCRI R-CHOP14v21 trial with combined analysis of molecular characteristics with the DSHNHL RICOVER-60 trial

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Outcome of major ABO-incompatible nonmyeloablative hematopoietic stem cell transplantation may be influenced by conditioning regimen

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Outcome of patients with relapsed diffuse large B-cell lymphoma who fail second-line salvage regimens in the International CORAL study.

scientific article published on 14 September 2015

Outcome of secondary myeloid malignancy in Hodgkin's disease: the BNLI experience

scientific article published on 01 August 1998

Outcomes after alemtuzumab-containing reduced-intensity allogeneic transplantation regimen for relapsed and refractory non-Hodgkin lymphoma

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Outcomes of diffuse large B-cell lymphoma patients relapsing after autologous stem cell transplantation: an analysis of patients included in the CORAL study

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PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways

scientific article published in April 2005

PIM and AKT kinase inhibitors show synergistic cytotoxicity in acute myeloid leukaemia that is associated with convergence on mTOR and MCL1 pathways

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Partial hypopituitarism following total body irradiation in adult patients with haematological malignancy.

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Paternal mosaicism proves the pathogenic nature of mutations in neutrophil elastase in severe congenital neutropenia

scientific article published on 01 July 2002

Pentoxifylline at clinically achievable levels inhibits FMLP-induced neutrophil responses, but not priming, upregulation of cell-adhesion molecules, or migration induced by GM-CSF

scientific article published on 01 January 1993

Peripheral blood progenitor cell transplantation: where do we stand? Chairman's Summary of the European School of Oncology Task Force meeting Peripheral Blood progenitor cell's held September 29-30, 1995.

scientific article published on January 1996

Peripheral blood stem cell support does not accelerate haemopoietic recovery from miniBEAM chemotherapy

scientific article published on 01 September 1996

Peripheral blood stem cell transplantation

scientific article published on 01 January 1997

Peripheral blood stem cell versus autologous bone marrow transplantation for Hodgkin's disease: equivalent survival outcome in a single-centre matched-pair analysis

scientific article published on 01 April 1999

Peripheral blood stem cell yield in 400 normal donors mobilised with granulocyte colony-stimulating factor (G-CSF): impact of age, sex, donor weight and type of G-CSF used

scientific article published in September 2006

Phenotypic analysis of fetal blood leucocytes: potential for prenatal diagnosis of immunodeficiency disorders

scientific article published on 01 July 1982

Phenotypic heterogeneity and evidence of a founder effect associated with G6PC3 mutations in patients with severe congenital neutropenia

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Phthalocyanine photosensitization for in vitro elimination of residual acute non-lymphoblastic leukaemia: preliminary evaluation

scientific article published on 01 November 1987

Placebo-controlled phase III trial of lenograstim in bone-marrow transplantation

scientific article published in March 1994

Plasma from patients with severe Lassa fever profoundly modulates f-met-leu-phe induced superoxide generation in neutrophils

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Platelet c-mpl expression is dysregulated in patients with essential thrombocythaemia but this is not of diagnostic value

scientific article published on 01 October 1999

Position paper on the therapeutic use of rituximab in CD20-positive diffuse large B-cell non-Hodgkin's lymphoma

scientific article published in April 2003

Preliminary results of autologous bone marrow transplantation in the management of resistant Hodgkin's disease: experience of the Bloomsbury Transplant Group at University College, London

scientific article published on 01 January 1989

Prenatal diagnosis for severe combined immunodeficiency

scientific article published on 01 January 1983

Prenatal diagnosis of severe combined immunodeficiency

scientific article published on 01 May 1982

Prenatal diagnosis of three cases of severe combined immunodeficiency: severe T cell deficiency during the first half of gestation in fetuses with adenosine deaminase deficiency

scientific article published on 01 May 1984

Priming of neutrophil function in the newborn

scientific article published on 01 June 2001

Primitive myeloid cells express high levels of phospholipase A(2) activity in the absence of leukotriene release: selective regulation by stem cell factor involving the MAP kinase pathway

scientific article published on 01 August 1999

Problems of mismatched bone marrow transplantation for severe combined immunodeficiency after soybean lectin fractionation

scientific article published on 01 January 1983

Progenitor cell yields are frequently poor in patients with histologically indolent lymphomas especially when mobilized within 6 months of previous chemotherapy

scientific article published on 01 June 1998

Progenitor-cell mobilization after low-dose cyclophosphamide and granulocyte colony-stimulating factor: an analysis of progenitor-cell quantity and quality and factors predicting for these parameters in 101 pretreated patients with malignant lymphom

scientific article published in February 1997

Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK Acute Lymphoblastic Leukemia 2003 trial

scientific article published on 08 March 2018

Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol

scientific article published on 27 July 2009

Prognostic implications of the presence of FLT3 mutations in patients with acute myeloid leukemia

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Prognostic indices in diffuse large B-cell lymphoma in the rituximab era: an analysis of the UK National Cancer Research Institute R-CHOP 14 versus 21 phase 3 trial

scientific article published on 20 May 2020

Prognostic role of PET scanning before and after reduced-intensity allogeneic stem cell transplantation for lymphoma

scientific article published on 02 February 2010

Prognostic significance of BCL-2 expression and bcl-2 major breakpoint region rearrangement in diffuse large cell non-Hodgkin's lymphoma: a British National Lymphoma Investigation Study

scientific article published in August 1996

Prognostic significance of CEBPA mutations in a large cohort of younger adult patients with acute myeloid leukemia: impact of double CEBPA mutations and the interaction with FLT3 and NPM1 mutations

scientific article published on 3 May 2010

Quantification of X-chromosome inactivation patterns in haematological samples using the DNA PCR-based HUMARA assay

scientific article published on 01 February 1996

Quantification of X-chromosome inactivation patterns using RT-PCR of the polymorphic iduronate-2-sulphatase gene and correlation of the results obtained with DNA-based techniques

scientific article published on 01 November 1998

RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years

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Raised neutrophil phospholipase A2 activity and defective priming of NADPH oxidase and phospholipase A2 in sickle cell disease

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Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients

scientific article published on 01 February 1996

Randomised vehicle-controlled dose-finding study of glycosylated recombinant human granulocyte colony-stimulating factor after bone marrow transplantation.

scientific article published on April 1993

Randomized comparison of the stanford V regimen and ABVD in the treatment of advanced Hodgkin's Lymphoma: United Kingdom National Cancer Research Institute Lymphoma Group Study ISRCTN 64141244.

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Rapid prenatal diagnosis of adenosine deaminase deficiency and other purine disorders using foetal blood

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Re-evaluation of progenitor thresholds and expectations for haematopoietic recovery based on an analysis of 810 autologous transplants: Implications for quality assurance

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Re-infused lymphocyte dose does not influence disease control following upfront autologous stem cell transplantation for multiple myeloma

scientific article published on 16 January 2012

Recombinant human granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for malignant lymphoma: a British National Lymphoma Investigation double-blind, placebo-controlled trial

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Red cell membrane protein anomalies in congenital dyserythropoietic anaemia, type II (HEMP AS)

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Red cell removal from donor bone marrow

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Reduced dose radiotherapy for local control in non-Hodgkin lymphoma: A randomised phase III trial

scientific article published on 12 June 2011

Reduced-intensity conditioning for allogeneic haematopoietic stem cell transplantation in relapsed and refractory Hodgkin lymphoma: impact of alemtuzumab and donor lymphocyte infusions on long-term outcomes.

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Reduced-intensity transplantation with in vivo T-cell depletion and adjuvant dose-escalating donor lymphocyte infusions for chemotherapy-sensitive myeloma: Limited efficacy of graft-versus-tumor activity

scientific article published on 01 April 2003

Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia

scientific article published on 16 August 2005

Remobilization of patients who fail to achieve minimal progenitor thresholds at the first attempt is clinically worthwhile

scientific article published on 01 October 2000

Reported cryptic rearrangements of CBFbeta-MYH11 in acute myeloid leukaemia are not due to false priming of contaminating DNA

scientific article published on 01 May 2000

Respiratory virus infections in transplant recipients after reduced-intensity conditioning with Campath-1H: high incidence but low mortality

scientific article published in December 2002

Risk of Second Malignancy After Non-Hodgkin's Lymphoma: A British Cohort Study

scientific article published on 06 March 2006

Risk of premature menopause after treatment for Hodgkin's lymphoma.

scientific article published on 19 August 2014

Risk of second malignancy after Hodgkin's disease in a collaborative British cohort: the relation to age at treatment

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Risk-adjusted prognostic models for Hodgkin's disease (HD) and grade II non-Hodgkin's lymphoma (NHL II): validation on 6728 British National Lymphoma Investigation patients.

scientific article published in January 2003

Rituximab in combination with CODOX-M/IVAC: a retrospective analysis of 23 cases of non-HIV related B-cell non-Hodgkin lymphoma with proliferation index >95%

scientific article published on 24 November 2010

Rituximab maintenance therapy after autologous stem-cell transplantation in patients with relapsed CD20(+) diffuse large B-cell lymphoma: final analysis of the collaborative trial in relapsed aggressive lymphoma

scientific article published on 22 October 2012

Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles

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Rituximab versus a watch-and-wait approach in patients with advanced-stage, asymptomatic, non-bulky follicular lymphoma: an open-label randomised phase 3 trial

scientific article published on 4 March 2014

Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) in the management of primary mediastinal B-cell lymphoma: a subgroup analysis of the UK NCRI R-CHOP 14 versus 21 trial

scientific article published in August 2016

Role of Nonmyeloablative Allogeneic Stem-Cell Transplantation After Failure of Autologous Transplantation in Patients With Lymphoproliferative Malignancies

scientific article published on 01 October 2002

Role of leucocyte integrins in phagocyte responses to granulocyte-macrophage colony stimulating factor (GM-CSF): in vitro and in vivo studies on leucocyte adhesion deficiency neutrophils

scientific article published on 01 February 1991

Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era

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Second cancer risk after chemotherapy for Hodgkin's lymphoma: a collaborative British cohort study

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Secretion of neutrophil secondary granules occurs during granulocyte-macrophage colony stimulating factor induced margination

scientific article published on 01 January 1990

Selective peripheral blood eosinophilia associated with survival advantage in Hodgkin's disease (BNLI Report No 31). British National Lymphoma Investigation

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Sequential high dose chemotherapy as initial treatment for aggressive sub-types of non-Hodgkin lymphoma: results of the international randomized phase III trial (MISTRAL).

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Simpson's Paradox and the Impact of Different DNMT3A Mutations on Outcome in Younger Adults With Acute Myeloid Leukemia.

scientific article published on 11 May 2015

Standards for PBSC mobilisation and collection

scientific article published on January 1996

Storage of PBSC at -80 degrees C

scientific article published on 01 January 1998

Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibit

scientific article published in October 2002

Studies of circulating hemopoietic progenitor cells in human fetal blood

scientific article published on 01 May 1982

Successful haploidentical mismatched bone marrow transplantation in severe combined immunodeficiency: T cell removal using CAMPATH-I monoclonal antibody and E-rosetting

scientific article published on 01 March 1986

Successful pregnancies in women following single autotransplant for acute myeloid leukemia with a chemotherapy ablation protocol

scientific article published on 01 April 1994

Successful response to intravenous immunoglobulin in autoimmune haemolytic anaemia

Successful treatment of refractory Hodgkin's disease by high-dose combination chemotherapy and autologous bone marrow transplantation

scientific article published on 01 January 1989

Superiority of reduced-intensity allogeneic transplantation over conventional treatment for relapse of Hodgkin's lymphoma following autologous stem cell transplantation

scientific article published on 14 January 2008

Survival and freedom from progression in autotransplant lymphoma patients is independent of stem cell source: further follow-up from the original randomised study to assess engraftment

scientific article published in March 2002

Survival of transfused adult cells in the fetus

scientific article published on 01 January 1986

T cell and monocyte requirements for erythropoiesis

scientific article published on 01 January 1982

T cell disorders in haematological diseases.

scientific article published on October 1982

T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia

scientific article published on 01 April 1986

T cell regeneration after allogeneic and autologous bone marrow transplantation

scientific article published on 01 March 1983

T-cell-depleted reduced-intensity transplantation followed by donor leukocyte infusions to promote graft-versus-lymphoma activity results in excellent long-term survival in patients with multiply relapsed follicular lymphoma

scientific article published on 6 July 2010

TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis

scientific article published on 3 July 2008

Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

scientific article published on 13 November 2017

The T-lineage-affiliated CD2 gene lies within an open chromatin environment in acute promyelocytic leukemia cells

scientific article published on 01 August 2002

The activating splice mutation in intron 3 of the thrombopoietin gene is not found in patients with non-familial essential thrombocythaemia

scientific article published on 01 September 1998

The addition of rituximab to fludarabine and cyclophosphamide chemotherapy results in a significant improvement in overall survival in patients with newly diagnosed mantle cell lymphoma: results of a randomized UK National Cancer Research Institute

scientific article published on 26 November 2015

The beta subunit common to the GM-CSF, IL-3 and IL-5 receptors is highly polymorphic but pathogenic point mutations in patients with acute myeloid leukaemia (AML) are rare.

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The c-myc oncogene is regulated independently of differentiation in myeloid cell lines

scientific article published in January 1989

The clinical impact of mutant DNMT3A R882 variant allele frequency in acute myeloid leukaemia

scientific article published on 31 January 2020

The clinical outcome of 65 cases of mantle cell lymphoma initially treated with non-intensive therapy by the British National Lymphoma Investigation Group

scientific article published on 01 December 1997

The cost-effectiveness of immediate treatment or watch and wait with deferred chemotherapy for advanced asymptomatic follicular lymphoma

scientific article published on 26 October 2017

The effect of inhibition of leukotriene synthesis on the activity of interleukin-8 and granulocyte-macrophage colony-stimulating factor.

scientific article published in January 1993

The effect of mitogenic lectins and monoclonal antibodies on intracellular free calcium concentration in human T-lymphocytes

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The effects of gestation on circulating progenitor cells

scientific article published on 01 July 1994

The effects of interleukin-8 on neutrophil fMetLeuPhe receptors, CD11b expression and metabolic activity, in comparison and combination with other cytokines

scientific article published on 01 August 1993

The effects of pertussis toxin on human T lymphocytes.

scientific article published in July 1988

The effects of recombinant human granulocyte-macrophage colony stimulating factor on the neutrophil respiratory burst in the term and preterm infant when studied in whole blood

scientific article published on 01 November 1994

The effects of recombinant human granulocyte-macrophage colony-stimulating factor on phagocyte kinetics in man

scientific article published on 01 August 1988

The effects of rhGM-CSF on the neutrophil respiratory burst when studied in whole blood

scientific article published on 01 June 1990

The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia

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The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: ...

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The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia

scientific article published on 20 June 2013

The morphology and cytochemistry of human T-cell subpopulations defined by monoclonal antibodies and Fc receptors

scientific article published on 01 August 1982

The outcome of haemopoietic stem cell transplantation in the treatment of lymphoplasmacytic lymphoma in the UK: a British Society Bone Marrow Transplantation study

scientific article published in April 2008

The phosphorylation state of the retinoblastoma (RB) protein in G0/G1 is dependent on growth status

scientific article published on February 1991

The place of high-dose BEAM therapy and autologous bone marrow transplantation in poor-risk Hodgkin's disease. A single-center eight-year study of 155 patients

scientific article published on 01 March 1993

The polymerase chain reaction in the demonstration of monoclonality in T cell lymphomas

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The predominant E2F complex in human primary haemopoietic cells and in AML blasts contains E2F-4, DP-1 and p130

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The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

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The production of JAK2 wild-type platelets is not downregulated in patients with JAK2 V617F mutant-positive essential thrombocythaemia.

scientific article published on 12 January 2009

The prognostic influence of mediastinal bulk in pathological stage IIA Hodgkin's disease treated initially with radiotherapy

scientific article published on 01 September 1989

The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status

scientific article published on 22 July 2010

The prognostic significance of IDH2 mutations in AML depends on the location of the mutation

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The regulation of neutrophil phospholipase A2 by granulocyte-macrophage colony-stimulating factor and its role in priming superoxide production

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The retinoblastoma gene (rb1) in acute myeloid leukaemia: analysis of gene rearrangements, protein expression and comparison of disease outcome.

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The role of allogeneic transplantation in non-Hodgkin's lymphoma

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The value of molecular stratification for CEBPA(DM) and NPM1(MUT) FLT3(WT) genotypes in older patients with acute myeloid leukaemia

scientific article published on 21 December 2015

The value of staging bone marrow trephine biopsy in Hodgkin's disease

scientific article published on 01 July 1987

Therapie einer Lymphknotentuberkulose

scientific article published on 01 August 2010

Tissue specificity of X-chromosome inactivation patterns

scientific article published on 01 May 1994

Toxicity of fludarabine and cyclophosphamide with or without rituximab as initial therapy for patients with previously untreated mantle cell lymphoma: results of a randomised phase II study

scientific article published in February 2009

Transcription-mediated amplification and hybridisation protection assay to determine BCR-ABL transcript levels in patients with chronic myeloid leukaemia

scientific article published in March 2002

Transient leucopenia induced by granulocyte-macrophage colony-stimulating factor

scientific article published on 01 December 1987

Transmigration of CD34+ cells across specialized and nonspecialized endothelium requires prior activation by growth factors and is mediated by PECAM-1 (CD31)

scientific article published on 01 February 1998

Transplant related septicaemia in patients undergoing autologous bone marrow transplantation for lymphoma and acute leukaemia

scientific article published on 01 January 1991

Treatment for lymph node tuberculosis

scientific article published in the British Medical Journal

Treatment of Hodgkin's lymphoma

scientific article published on August 8, 1992

Treatment of T cell proliferation with monoclonal antibody

scientific article published on 01 September 1981

Treatment of a low grade T cell proliferation with monoclonal antibody

scientific article published on 01 January 1983

Treatment of classical Hodgkin lymphoma in young adults aged 18-30 years with a modified paediatric Hodgkin lymphoma protocol. Results of a multicentre phase II clinical trial (CRUK/08/012)

scientific article published on 11 November 2019

Treatment of diffuse large B-cell lymphoma with secondary central nervous system involvement: encouraging efficacy using CNS-penetrating R-IDARAM chemotherapy

scientific article published on 18 December 2015

Treatment of the elderly patient with diffuse large B cell lymphoma

scientific article published on 16 January 2012

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

scientific article published on 27 June 2006

Unusual T cell proliferations and neutropenia in rheumatoid arthritis: comparison with classical Felty's syndrome

scientific article published on 01 October 1984

Unusual phenotype and function of an expanded subpopulation of T cells in patients with haemopoietic disorders

scientific article published on 01 March 1981

Use of 18F-FDG positron emission tomography following allogeneic transplantation to guide adoptive immunotherapy with donor lymphocyte infusions

scientific article published in March 2005

Use of the haemopoietic progenitor cell count of the Sysmex SE-9500 to refine apheresis timing of peripheral blood stem cells

scientific article published on 01 August 1999

Variable expression of p16 protein in patients with acute myeloid leukemia without gross rearrangements at the DNA level.

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Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment

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Variable product purity and functional capacity after CD34 selection: a direct comparison of the CliniMACS (v2.1) and Isolex 300i (v2.5) clinical scale devices

scientific article published in July 2002

Very high dose chemotherapy with autologous bone marrow rescue in adult patients with resistant relapsed lymphoma.

scientific article published in January 1986

WT1 mutations in T-ALL

scientific article published on 03 June 2009

X chromosome inactivation analysis reveals a difference in the biology of ET patients with JAK2 and CALR mutations

scientific article published on 19 August 2014

X-chromosome inactivation patterns using HPRT and PGK polymorphisms in haematologically normal and post-chemotherapy females.

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c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia

scientific article published on 01 June 1999